FR3035009B1 - Dispositif microfluidique de controle d'ecoulement d'un fluide - Google Patents

Dispositif microfluidique de controle d'ecoulement d'un fluide Download PDF

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Publication number
FR3035009B1
FR3035009B1 FR1553487A FR1553487A FR3035009B1 FR 3035009 B1 FR3035009 B1 FR 3035009B1 FR 1553487 A FR1553487 A FR 1553487A FR 1553487 A FR1553487 A FR 1553487A FR 3035009 B1 FR3035009 B1 FR 3035009B1
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FR
France
Prior art keywords
fluid
flow
controlling
microfluidic device
interest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1553487A
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English (en)
Other versions
FR3035009A1 (fr
Inventor
Remco Den Dulk
Yves Fouillet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR1553487A priority Critical patent/FR3035009B1/fr
Priority to EP16166022.0A priority patent/EP3085444B1/fr
Publication of FR3035009A1 publication Critical patent/FR3035009A1/fr
Application granted granted Critical
Publication of FR3035009B1 publication Critical patent/FR3035009B1/fr
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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)

Abstract

L'invention porte sur un dispositif microfluidique de contrôle d'écoulement d'au moins un fluide d'intérêt, comportant un réseau microfluidique (3) comprenant au moins une suite de chambres microfluidiques (5) reliées entre elles de manière séquentielle, chaque chambre microfluidique étant commutable entre un premier état fermé bloquant l'écoulement du fluide d'intérêt et un second état ouvert allouant un volume prédéterminé à ladite chambre tout en pompant le fluide d'intérêt dans ladite chambre.
FR1553487A 2015-04-20 2015-04-20 Dispositif microfluidique de controle d'ecoulement d'un fluide Active FR3035009B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1553487A FR3035009B1 (fr) 2015-04-20 2015-04-20 Dispositif microfluidique de controle d'ecoulement d'un fluide
EP16166022.0A EP3085444B1 (fr) 2015-04-20 2016-04-19 Dispositif microfluidique de contrôle d'écoulement d'un fluide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1553487 2015-04-20
FR1553487A FR3035009B1 (fr) 2015-04-20 2015-04-20 Dispositif microfluidique de controle d'ecoulement d'un fluide

Publications (2)

Publication Number Publication Date
FR3035009A1 FR3035009A1 (fr) 2016-10-21
FR3035009B1 true FR3035009B1 (fr) 2020-02-07

Family

ID=53274736

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1553487A Active FR3035009B1 (fr) 2015-04-20 2015-04-20 Dispositif microfluidique de controle d'ecoulement d'un fluide

Country Status (2)

Country Link
EP (1) EP3085444B1 (fr)
FR (1) FR3035009B1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3058995B1 (fr) 2016-11-18 2021-02-19 Commissariat Energie Atomique Procede et systeme de commande d'un dispositif microfluidique
FR3074069A1 (fr) * 2017-11-28 2019-05-31 Commissariat A L'energie Atomique Et Aux Energies Alternatives Dispositif d'injection d'un echantillon fluidique
FR3107901A1 (fr) 2020-03-09 2021-09-10 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procédé de perfusion micro-fluidique d'un sphéroïde et dispositif adapté pour mettre en œuvre ledit procédé
CN115078752B (zh) * 2022-08-16 2022-10-28 广州誉康医药有限公司 多通道取样及加样系统、方法以及包含该系统的检测仪
CN115078753B (zh) * 2022-08-18 2022-10-28 广州誉康医药有限公司 多通道取样、加样及清洗系统、方法和含该系统的检测仪
CN115970781B (zh) * 2023-03-21 2024-01-12 杭州霆科生物科技有限公司 一种定量加样结构及其浓度梯度微流控芯片和控制方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7832429B2 (en) * 2004-10-13 2010-11-16 Rheonix, Inc. Microfluidic pump and valve structures and fabrication methods
US7763453B2 (en) * 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US7976795B2 (en) * 2006-01-19 2011-07-12 Rheonix, Inc. Microfluidic systems
FR2897282B1 (fr) 2006-02-16 2008-05-30 Commissariat Energie Atomique Procede de controle de l'avancee d'un liquide dans un compos ant microfluidique
KR20120030130A (ko) * 2009-06-02 2012-03-27 인터젠엑스 인크. 다이아프램 밸브를 포함하는 유체 장치
WO2011094577A2 (fr) * 2010-01-29 2011-08-04 Micronics, Inc. Cartouche microfluidique « de l'échantillon au résultat »
CN103157523A (zh) * 2011-12-15 2013-06-19 三星电子株式会社 微流器件及其制造方法

Also Published As

Publication number Publication date
EP3085444A1 (fr) 2016-10-26
EP3085444B1 (fr) 2023-03-08
FR3035009A1 (fr) 2016-10-21

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