FR3030049B1 - SYSTEM OF ANALYSIS AND CELL CULTURE, METHOD OF ANALYSIS AND ASSOCIATED CELL CULTURE AND METHOD OF MANUFACTURING THE ASSOCIATED CHIP - Google Patents

SYSTEM OF ANALYSIS AND CELL CULTURE, METHOD OF ANALYSIS AND ASSOCIATED CELL CULTURE AND METHOD OF MANUFACTURING THE ASSOCIATED CHIP Download PDF

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Publication number
FR3030049B1
FR3030049B1 FR1462259A FR1462259A FR3030049B1 FR 3030049 B1 FR3030049 B1 FR 3030049B1 FR 1462259 A FR1462259 A FR 1462259A FR 1462259 A FR1462259 A FR 1462259A FR 3030049 B1 FR3030049 B1 FR 3030049B1
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France
Prior art keywords
analysis
cell culture
chip
manufacturing
duct
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FR1462259A
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French (fr)
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FR3030049A1 (en
Inventor
Andrew David Griffiths
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Individual
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Priority to FR1462259A priority Critical patent/FR3030049B1/en
Publication of FR3030049A1 publication Critical patent/FR3030049A1/en
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Publication of FR3030049B1 publication Critical patent/FR3030049B1/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements

Abstract

L'invention concerne un système d'analyse et de culture cellulaire (40) comprenant : - une source d'un premier fluide comprenant un premier réactif, - une puce (44) comprenant un conduit d'entrée comportant une première entrée (18) reliée à la source et une sortie, au moins un conduit de passage (12) du premier fluide, dans lequel débouche la sortie du conduit d'entrée. La puce (44) comprend en outre, pour chaque conduit de passage (12) un réservoir (14), débouchant dans le conduit de passage (12). Le réservoir (14) contient une solution pré-chargée, comprenant un deuxième réactif apte à réagir avec le premier réactif dans le conduit de passage (12).The invention relates to an analysis and cell culture system (40) comprising: - a source of a first fluid comprising a first reagent, - a chip (44) comprising an inlet duct comprising a first inlet (18) connected to the source and an outlet, at least one passage duct (12) of the first fluid, into which the outlet of the inlet duct opens. The chip (44) further comprises, for each passage duct (12), a reservoir (14), opening into the passage duct (12). The reservoir (14) contains a pre-loaded solution, comprising a second reagent capable of reacting with the first reagent in the passage duct (12).

FR1462259A 2014-12-11 2014-12-11 SYSTEM OF ANALYSIS AND CELL CULTURE, METHOD OF ANALYSIS AND ASSOCIATED CELL CULTURE AND METHOD OF MANUFACTURING THE ASSOCIATED CHIP Active FR3030049B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR1462259A FR3030049B1 (en) 2014-12-11 2014-12-11 SYSTEM OF ANALYSIS AND CELL CULTURE, METHOD OF ANALYSIS AND ASSOCIATED CELL CULTURE AND METHOD OF MANUFACTURING THE ASSOCIATED CHIP

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1462259A FR3030049B1 (en) 2014-12-11 2014-12-11 SYSTEM OF ANALYSIS AND CELL CULTURE, METHOD OF ANALYSIS AND ASSOCIATED CELL CULTURE AND METHOD OF MANUFACTURING THE ASSOCIATED CHIP

Publications (2)

Publication Number Publication Date
FR3030049A1 FR3030049A1 (en) 2016-06-17
FR3030049B1 true FR3030049B1 (en) 2020-11-13

Family

ID=52469172

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1462259A Active FR3030049B1 (en) 2014-12-11 2014-12-11 SYSTEM OF ANALYSIS AND CELL CULTURE, METHOD OF ANALYSIS AND ASSOCIATED CELL CULTURE AND METHOD OF MANUFACTURING THE ASSOCIATED CHIP

Country Status (1)

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FR (1) FR3030049B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023119434A (en) * 2022-02-16 2023-08-28 ウシオ電機株式会社 Microfluidic device and method of using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009061392A1 (en) * 2007-11-05 2009-05-14 President And Fellows Of Harvard College Forming gel structures using microfluidic channels
US8748180B2 (en) * 2009-07-29 2014-06-10 Cornell University Microfluidic device for pharmacokinetic-pharmacodynamic study of drugs and uses thereof
KR101307196B1 (en) * 2011-07-15 2013-09-12 국립대학법인 울산과학기술대학교 산학협력단 Cell culture device

Also Published As

Publication number Publication date
FR3030049A1 (en) 2016-06-17

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