FR3011932B1 - Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillons - Google Patents
Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillonsInfo
- Publication number
- FR3011932B1 FR3011932B1 FR1359860A FR1359860A FR3011932B1 FR 3011932 B1 FR3011932 B1 FR 3011932B1 FR 1359860 A FR1359860 A FR 1359860A FR 1359860 A FR1359860 A FR 1359860A FR 3011932 B1 FR3011932 B1 FR 3011932B1
- Authority
- FR
- France
- Prior art keywords
- time
- measurement device
- fluorescence measurement
- resolved fluorescence
- speed sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6445—Measuring fluorescence polarisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
- G01N2021/035—Supports for sample drops
- G01N2021/0353—Conveyor of successive sample drops
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N2021/6417—Spectrofluorimetric devices
- G01N2021/6421—Measuring at two or more wavelengths
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
- G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6482—Sample cells, cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/05—Flow-through cuvettes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1359860A FR3011932B1 (fr) | 2013-10-10 | 2013-10-10 | Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillons |
EP14783629.0A EP3055675A1 (fr) | 2013-10-10 | 2014-10-10 | Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillons |
PCT/EP2014/071808 WO2015052331A1 (fr) | 2013-10-10 | 2014-10-10 | Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillons |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1359860A FR3011932B1 (fr) | 2013-10-10 | 2013-10-10 | Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillons |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3011932A1 FR3011932A1 (fr) | 2015-04-17 |
FR3011932B1 true FR3011932B1 (fr) | 2017-03-24 |
Family
ID=49817012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1359860A Expired - Fee Related FR3011932B1 (fr) | 2013-10-10 | 2013-10-10 | Dispositif et procede de mesure de fluorescence resolue en temps pour le criblage a haut debit d'echantillons |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP3055675A1 (fr) |
FR (1) | FR3011932B1 (fr) |
WO (1) | WO2015052331A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11086119B2 (en) * | 2018-02-16 | 2021-08-10 | Leica Microsystems Cms Gmbh | Fluorescence-lifetime imaging microscopy method having time-correlated single-photon counting |
US11726081B2 (en) | 2019-02-15 | 2023-08-15 | Regents Of The University Of Minnesota | Methods to identify modulators of tau protein structure |
US11656221B2 (en) | 2019-06-11 | 2023-05-23 | Regents Of The University Of Minnesota | Methods to identify modulators of actin-binding proteins |
US11969259B2 (en) | 2020-02-21 | 2024-04-30 | Hi Llc | Detector assemblies for a wearable module of an optical measurement system and including spring-loaded light-receiving members |
US11950879B2 (en) * | 2020-02-21 | 2024-04-09 | Hi Llc | Estimation of source-detector separation in an optical measurement system |
WO2023275738A1 (fr) * | 2021-06-28 | 2023-01-05 | Ecole Polytechnique Federale De Lausanne (Epfl) | Méthode et dispositif pour réaliser une spectroscopie trouverte |
CN114280025B (zh) * | 2021-12-28 | 2024-05-03 | 核工业北京地质研究院 | 一种溶液中铀含量测量装置及测量方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7193706B2 (en) * | 2000-08-02 | 2007-03-20 | Arizona Board Of Regents, Acting On Behalf Of Arizona State University | Computer interfaced scanning fluorescence lifetime microscope applied to directed evolution |
EP2530167A1 (fr) * | 2006-05-11 | 2012-12-05 | Raindance Technologies, Inc. | Dispositifs microfluidiques |
WO2011008233A1 (fr) * | 2009-05-07 | 2011-01-20 | President And Fellows Of Harvard College | Procédés et appareils de détection fluorimétrique employant des plaques à zone de fresnel |
-
2013
- 2013-10-10 FR FR1359860A patent/FR3011932B1/fr not_active Expired - Fee Related
-
2014
- 2014-10-10 EP EP14783629.0A patent/EP3055675A1/fr not_active Withdrawn
- 2014-10-10 WO PCT/EP2014/071808 patent/WO2015052331A1/fr active Application Filing
Also Published As
Publication number | Publication date |
---|---|
FR3011932A1 (fr) | 2015-04-17 |
EP3055675A1 (fr) | 2016-08-17 |
WO2015052331A1 (fr) | 2015-04-16 |
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