FR2953932B1 - Procede de separation et de detection d'un analyte - Google Patents

Procede de separation et de detection d'un analyte

Info

Publication number
FR2953932B1
FR2953932B1 FR1060289A FR1060289A FR2953932B1 FR 2953932 B1 FR2953932 B1 FR 2953932B1 FR 1060289 A FR1060289 A FR 1060289A FR 1060289 A FR1060289 A FR 1060289A FR 2953932 B1 FR2953932 B1 FR 2953932B1
Authority
FR
France
Prior art keywords
analyte
separating
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1060289A
Other languages
English (en)
French (fr)
Other versions
FR2953932A1 (fr
Inventor
Renato Belz
Andreas Gisler
Robert Huesler
Rolf Knobel
Christian Thalmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2953932A1 publication Critical patent/FR2953932A1/fr
Priority to FR1553101A priority Critical patent/FR3020140B1/fr
Application granted granted Critical
Publication of FR2953932B1 publication Critical patent/FR2953932B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00277—Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00326—Analysers with modular structure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Robotics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR1060289A 2009-12-10 2010-12-09 Procede de separation et de detection d'un analyte Active FR2953932B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR1553101A FR3020140B1 (fr) 2009-12-10 2015-04-10 Systeme analytique pour traiter un analyte

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09178713 2009-12-10
EP10158862 2010-03-31

Publications (2)

Publication Number Publication Date
FR2953932A1 FR2953932A1 (fr) 2011-06-17
FR2953932B1 true FR2953932B1 (fr) 2015-05-22

Family

ID=43718406

Family Applications (2)

Application Number Title Priority Date Filing Date
FR1060289A Active FR2953932B1 (fr) 2009-12-10 2010-12-09 Procede de separation et de detection d'un analyte
FR1553101A Active FR3020140B1 (fr) 2009-12-10 2015-04-10 Systeme analytique pour traiter un analyte

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR1553101A Active FR3020140B1 (fr) 2009-12-10 2015-04-10 Systeme analytique pour traiter un analyte

Country Status (7)

Country Link
US (3) US8530229B2 (enExample)
EP (1) EP2333559B1 (enExample)
JP (1) JP5872765B2 (enExample)
CN (1) CN102141572B (enExample)
CA (1) CA2724132C (enExample)
DE (1) DE102010053913A1 (enExample)
FR (2) FR2953932B1 (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2724106C (en) * 2009-12-10 2018-04-17 F. Hoffmann-La Roche Ag Multiwell plate and lid
CA2724132C (en) * 2009-12-10 2018-03-06 F. Hoffmann-La Roche Ag Amplification system with spatial separation
JP5872786B2 (ja) * 2010-04-19 2016-03-01 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ マルチウェル・プレートを備えたカセット
EP2607904B1 (en) * 2011-12-21 2020-01-15 Roche Diagnostics GmbH Method for disposing of a liquid within an automated analytical system, tip rack assembly and analytical system
FR2999012B1 (fr) * 2012-11-30 2017-12-15 Primadiag S A S Module d'attraction magnetique, robot comprenant un tel module, et procede d'utilisation sur billes magnetiques d'un tel module ou d'un tel robot
EP2789389B1 (de) * 2013-04-12 2015-07-29 Eppendorf Ag Vorrichtung zum Bereitstellen von Pipettenspitzen
CH708139A2 (de) * 2013-06-06 2014-12-15 Tecan Trading Ag Pipettiervorrichtung.
CN104786028B (zh) * 2014-01-21 2017-09-22 林顺安 微孔板组装设备和组装方法
EP2929939A1 (en) * 2014-04-07 2015-10-14 Yantai AusBio Laboratories Co., Ltd. Microplate
WO2016130962A1 (en) 2015-02-13 2016-08-18 Abbott Laboratories Automated storage modules for diagnostic analyzer liquids and related systems and methods
CA3129007A1 (en) * 2015-04-06 2016-10-13 Eli N. Glezer High throughput system for performing assays using electrochemiluminescence including a consumable shaking apparatus
EP3088306A1 (en) * 2015-04-27 2016-11-02 Roche Diagniostics GmbH Recapper, laboratory automation system and method of recapping a sample container
EP3862755B1 (en) 2016-02-17 2025-01-15 Becton, Dickinson and Company Container shuttle transport assembly
CN105628687B (zh) * 2016-02-24 2018-08-07 南京诺尔曼生物技术有限公司 一种全自动化学发光测定仪
WO2017184244A1 (en) * 2016-04-22 2017-10-26 Becton. Dickinson And Company Automated diagnostic analyzer and method for its operation
US11199560B2 (en) 2016-04-22 2021-12-14 Becton Dickinson And Company Automated diagnostic analyzer and method for its operation
DE112017005675T5 (de) * 2016-11-11 2019-09-05 Brio Apps Alphasip, S.L. System zum Durchführen chemischer, biologischer und/oder medizinischer Prozesse
CN110914447A (zh) * 2017-01-26 2020-03-24 生物辐射实验室股份有限公司 包括水性样品稳定化的测定执行系统
CN106984066A (zh) * 2017-06-06 2017-07-28 利穗科技(苏州)有限公司 一种层析柱维护柱架
WO2019082436A1 (ja) * 2017-10-23 2019-05-02 株式会社島津製作所 サンプルプレート及びオートサンプラ
USD886321S1 (en) 2018-01-19 2020-06-02 Biotix, Inc. Pipette tip rack assembly
WO2019169347A1 (en) 2018-03-02 2019-09-06 10X Genomics, Inc. Systems and apparatus for holding plates
JP6694486B2 (ja) 2018-03-29 2020-05-13 バイオティクス， インコーポレイテッド 剛性を高められたピペットチップトレイ
USD888280S1 (en) * 2018-03-29 2020-06-23 Biotix, Inc. Pipette tip tray
USD923816S1 (en) 2019-03-20 2021-06-29 Biotix, Inc. Pipette tip tray
WO2020257672A1 (en) * 2019-06-19 2020-12-24 Life Technologies Corporation Reagent container and methods of use
DE102020126552A1 (de) * 2020-10-09 2022-04-14 Syntegon Technology Gmbh Nestausheber und Sterilkammer
US11878304B2 (en) * 2020-12-23 2024-01-23 Tecan Trading Ag Receiving frame for receiving a support plate for pipette tips
US11701663B2 (en) * 2021-06-28 2023-07-18 Xcaliber Sciences, Inc. Pipette tip system
US20240369587A1 (en) * 2021-09-07 2024-11-07 Becton, Dickinson And Company Apparatus and method for inventory handling in an automated diagnostic analyzer
USD1066739S1 (en) * 2021-09-28 2025-03-11 Xcaliber Sciences, Inc. Pipette tip storage assembly
CN114570450B (zh) * 2022-03-04 2025-11-11 莱杰生物科技(苏州)有限公司 一种叠装有吸头架的空心盒体
WO2024163768A2 (en) * 2023-02-03 2024-08-08 Somalogic Operating Co., Inc. Systems and methods for magnetically separating mixtures
USD1068109S1 (en) * 2023-07-11 2025-03-25 Xcaliber Sciences, Inc. Pipette tip storage assembly
USD1067463S1 (en) * 2023-07-11 2025-03-18 Xcaliber Sciences, Inc. Pipette tip storage assembly
DE102024101354A1 (de) * 2024-01-17 2025-07-17 Hamilton Bonaduz Ag Pipettier-Labormodul mit besonderer Beschickung der Pipettiervorrichtung des Pipettier-Labormoduls

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69841255D1 (de) 1997-11-14 2009-12-03 Gen Probe Inc Arbeitsgerät zur Analyse
DE10011555T1 (de) * 1998-05-01 2012-02-02 Gen-Probe Inc. Automatisches Diagnoseanalysegerät und Verfahren
CA2346268A1 (en) * 1998-10-16 2000-04-27 Intelligent Automation Systems Continuous processing automated workstation
US5984844A (en) * 1998-10-21 1999-11-16 Royer; Marc A. Portable exercise device
EP1257354A2 (en) * 2000-02-22 2002-11-20 Genospectra, Inc. Microarray fabrication techniques and apparatus
US6705242B2 (en) * 2002-01-08 2004-03-16 Ch2M Hill Constructors, Inc. Method and apparatus for hermetically sealing openings of an explosion containment chamber
GB0227765D0 (en) * 2002-11-28 2003-01-08 Secr Defence Apparatus for processing a fluid sample
WO2005009202A2 (en) * 2003-05-12 2005-02-03 Isis Pharmaceuticals, Inc. Automatic identification of bioagents
US20050226771A1 (en) 2003-09-19 2005-10-13 Lehto Dennis A High speed microplate transfer
JP4756835B2 (ja) 2004-07-14 2011-08-24 キヤノン株式会社 生化学反応カートリッジ
DE102004036063A1 (de) * 2004-07-24 2006-02-16 Krones Ag Vorrichtung und Verfahren zur Plasmabeschichtung/Sterilisation
US20060257999A1 (en) * 2005-03-22 2006-11-16 Chang Jim Y Compound profiling devices, systems, and related methods
US20070184463A1 (en) * 2005-09-30 2007-08-09 Caliper Life Sciences, Inc. Microfluidic device for purifying a biological component using magnetic beads
CN101370622B (zh) 2006-01-18 2013-07-31 阿戈斯治疗公司 用于处理封闭容器中的样品的系统和方法以及相关装置
JP2008170332A (ja) * 2007-01-12 2008-07-24 Anritsu Sanki System Co Ltd 分注装置
JP2009222634A (ja) * 2008-03-18 2009-10-01 Panasonic Corp マイクロプレートの処理装置
US20110009608A1 (en) * 2008-04-09 2011-01-13 Bioneer Corporation Automatic refining apparatus, multi-well plate kit and method for extracting hexane from biological samples
CA2724132C (en) * 2009-12-10 2018-03-06 F. Hoffmann-La Roche Ag Amplification system with spatial separation

Also Published As

Publication number Publication date
DE102010053913A1 (de) 2011-12-15
US9365895B2 (en) 2016-06-14
US20110306053A1 (en) 2011-12-15
CA2724132A1 (en) 2011-06-10
JP2011123067A (ja) 2011-06-23
FR3020140A1 (enExample) 2015-10-23
CN102141572A (zh) 2011-08-03
US8530229B2 (en) 2013-09-10
EP2333559A1 (en) 2011-06-15
US20130323826A1 (en) 2013-12-05
FR3020140B1 (fr) 2019-12-27
FR2953932A1 (fr) 2011-06-17
US20130323741A1 (en) 2013-12-05
JP5872765B2 (ja) 2016-03-01
CA2724132C (en) 2018-03-06
US8809039B2 (en) 2014-08-19
EP2333559B1 (en) 2021-01-27
CN102141572B (zh) 2015-11-25

Similar Documents

Publication Publication Date Title
FR2953932B1 (fr) Procede de separation et de detection d'un analyte
EP2683810A4 (en) METHOD AND SYSTEM FOR CELL DETECTION AND ANALYSIS
EP2372055A4 (en) DEVICE AND METHOD FOR DETECTING ANOMALITY OF A DOOR OPENER SWITCH
FR2931079B1 (fr) Dispositif et procede de separation d'une suspension
EP2058666A4 (en) MICROPLATE SEPARATION DEVICE AND MICROPLATE SEPARATION METHOD
EP2238680A4 (en) METHOD AND SYSTEM FOR MULTI-PHASE POWER DETECTION
GB2475742B (en) Sample collection and detection system
EP2443589A4 (en) METHOD AND SYSTEM FOR SEARCHING DUPLICATE PICTURES
EP1801757A4 (en) DETECTOR FOR ABNORME ACTION AND DETECTION METHOD FOR ABNORME ACTION
EP2407081A4 (en) POSITION RECOGNITION SYSTEM AND POSITION DETECTION METHOD
FR2963437B1 (fr) Procede de detection et d'exclusion de multi-pannes satellites
FR2973883B1 (fr) Procede et systeme de detection d'un court-circuit affectant un capteur
EP2404166A4 (en) SYSTEM AND METHOD FOR DETECTING THE CONDUCTIVITY
FR2932885B1 (fr) Procede et dispositif de detection de la fluorescence d'une biopuce
FR2942388B1 (fr) Systeme et procede de detection de marche d'une personne
FR2962222B1 (fr) Procede de detection d'interactions moleculaires
FR2945120B1 (fr) Systeme et procede de detection de rayonnement infrarouge
FR2928093B1 (fr) Dispositif de separation de molecules et procede de fabrication.
FR2963682B1 (fr) Procede de detection d'objet au moyen d'un capteur de proximite
EP2407960A4 (en) METHOD AND DEVICE FOR DETECTING AUDIO SIGNALS
FR2958298B1 (fr) Procede de detection d'amas de particules biologiques
FR2943901B1 (fr) Procede et systeme de detection d'anomalies oculomotrices.
FR2953292B1 (fr) Capteur d'hydrogene et procede de detection d'une concentration en hydrogene.
FR2950435B1 (fr) Dispositif et procede de detection d'un gaz
FR2968314B1 (fr) Procede de detection et de quantification de microorganismes

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 6

PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 10

PLFP Fee payment

Year of fee payment: 11

PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

PLFP Fee payment

Year of fee payment: 14

PLFP Fee payment

Year of fee payment: 15

PLFP Fee payment

Year of fee payment: 16