FR2922103A1 - USE OF A COSMETIC COMPOSITION COMPRISING A CYCLIC SILICONE COPOLYMER FOR IMPROVING MAKE-UP FIXATION - Google Patents

Abstract

The present invention relates to the use of a cosmetic composition containing, in a cosmetically acceptable medium, at least one non-crosslinked cyclic silicone copolymer and at least one solvent selected from linear silicones, cyclic silicones, hydrocarbons and mixtures thereof, for to improve the fixing and / or holding of skin makeup compositions. It also relates to a make-up kit, comprising a cosmetic composition containing at least one non-crosslinked cyclic silicone copolymer; and at least one skin makeup composition.

Description

The present invention relates to the use of a cosmetic composition containing at least one uncrosslinked cyclic silicone copolymer for improving the fixing and / or the holding of a cosmetic composition. makeup composition of the skin. The invention also relates to a makeup kit comprising said cosmetic composition and at least one makeup composition for the skin.

The term "skin makeup composition" in the present invention means a cosmetic composition comprising, in a physiologically acceptable medium, at least one dyestuff in an amount sufficient to color the skin. There may be mentioned a foundation, a concealer, a concealer and a powder such as in particular a two-way cake.

The dyestuffs may be chosen from water-soluble or fat-soluble dyes, mineral pigments, pearlescent agents, lacquers and mixtures thereof. These dyestuffs may optionally be surface-treated with a hydrophobic agent such as silanes, silicones, fatty acid soaps, C 9-15 fluoroalcohol phosphates, acrylate / dimethicone copolymers, mixed copolymers C 9 -C 15 fluoroalcohol phosphates / silicones, lecithins, wax carnauba, polyethylene, chitosan and optionally acylated amino acids such as lauroyl lysine, disodium stearoyl glutamate and aluminum acyl glutamate.

Facial foundations are often recommended for people with skin problems such as acne, redness and scarring, as well as for those seeking a camouflaging, smoothing and tensing effect to hide surface irregularities such as wrinkles. and the fine lines of the face. More simply, foundations can be used to brighten, evenify, brighten or mattify the complexion.

The complexion correctors and concealer products are highly concentrated in color pigments and have a high covering power. They can be applied uniformly all over the face or locally on imperfections such as redness or unsightly pimples. The correctors can be applied below the foundation for a natural result.

Two-way cakes are cosmetic powders that are in the form of compacted products that can be taken either by dry applicator or dry sponge like conventional powders or by using water. a wet sponge and then serve as a foundation.

It has been observed that skin makeup compositions tend to have poor durability over time. This poor behavior over time can be characterized by a change in color by turning or paling, usually as a result of an interaction with sebum and / or sweat secreted by the skin. It then becomes necessary to renew the application. However, to date, users want to beautify their faces by spending as little time as possible.

Therefore, there remains the need to provide a means for improving the fixation and / or holding, both during the application and over time, a skin makeup composition.

However, the Applicant has now discovered that it is possible to use for this purpose at least one uncrosslinked cyclic silicone copolymer in a cosmetic composition.

The subject of the present invention is therefore the use of a cosmetic composition containing, in a cosmetically acceptable medium, at least one non-crosslinked cyclic silicone copolymer and at least one solvent chosen from linear silicones, cyclic silicones, hydrocarbons and their derivatives. mixtures, for improving the fixation and / or holding of skin makeup compositions.

Advantageously, said uncrosslinked cyclic silicone copolymer is represented by the formula (1): A (B-A) z B (1) in which z is an integer from 2 to 2000; A is a silicone polymer with disilanehydrogen ends of formula (2). Ak Ak Ak H-Si - (- O-Si---O-Si-H 1 1 X Ak Ak Ak wherein x is an integer of 0 at 5000 and Ak is a C1-C6 alkyl such as methyl, and

B is a silicone polymer with divinyl ends of formula (3). Ak Ak Ak

1 - (CH 2) -S 1- (O-Si -) - O-Si- (CH 2) -2 I y 2 Ak Ak Ak wherein

y is an integer from 0 to 5000 and Ak is a C1-C6 alkyl such as methyl. In a preferred embodiment, x has a value between 5 and 200, preferably between 10 and 100, and even more preferably between 10 and 50. In a preferred embodiment, there is a value between 5 and 200, of preferably between 10 and 100, and even more preferably between 10 and 50.

The copolymers of formula (1) are known to be lipophilic gelling agents and are, for example, sold by the company JEEN under the trade name JEESILC ° PS (2) (3) 20 (including PS-VH, PS-VHLV, PS -CM, PSCMLV and PS-DMLV). It is preferred to use the INCI name product cyclopentasiloxane & bisvinyl dimethicone / dimethicone copolymer sold under the brand JEESILC PS-CM °.

Alternatively, the uncrosslinked cyclic silicone copolymers of formula (1) may be prepared according to a known method which consists in reacting a disilane-hydrogen end polymer of formula (2), in which x is defined as above, with a polymer with divinyl ends of formula (3), wherein y is defined as above, in a solvent selected from linear silicones, cyclic silicones, hydrocarbons and mixtures thereof. The reaction is generally carried out in the presence of a catalyst suitable for hydrosilylation such as choroplatinic acid and Karstedt catalyst.

Among the linear silicones, mention may in particular be made of volatile and non-volatile polydimethylsiloxanes and in particular those of formula:

(CH3) 3-Si-O- [Si (CH3) 2-O] n-Si- (CH3) 3 wherein n is an integer of 0 to 7, and preferably 0 to 5.

Among the cyclic silicones, mention may be made especially of those of the formula:

- (Si (CH 3) 2-O) n-25 wherein n is an integer of 3 to 6.

Linear and cyclic silicones are marketed by many companies such as Dow Corning Corporation, Shin-Etsu, Siltech Corp. and Momentive Performance Materials formerly GE Silicones. Mention may be made, in particular, of the silicones of the Dow Corning trade names 244 °, 245 °, 344 and 200 Fluids.

Among the hydrocarbons, mention may in particular be made of linear or branched hydrocarbons comprising from 5 to 40 carbon atoms, and preferably from 8 to 20 carbon atoms such as pentane, hexane, heptane, decane and dodecane. , tetradecane, tridecane and isoparaffins comprising 8 to 20 carbon atoms such as isododecane, isohexadecane and those described in patents US-3,439,088 and US-3,818,105.

The particularly preferred hydrocarbons have the following physicochemical properties: a molecular weight of between about 70 and about 225 g / mol, preferably between 160 and 190 g / mol, a boiling point of between about 30 ° C. and about 320 ° C, preferably from about 60 ° C to about 260 ° C, and a viscosity of from less than 10-5 m2 / s (10 centistokes) to 25 ° C.

For example, mention may be made of the hydrocarbons marketed under the trademark Isopars ° by the company Exxon Mobil, and the C12 isoparaffins marketed under the trade name Permethyl 99A by the company Permethyl Corporation.

Advantageously, it is preferred to use silicone solvents and in particular a cyclomethicone such as cyclopentasiloxane.

Advantageously, the ratio of the uncrosslinked cyclic silicone copolymer to the solvent is between about 2:98 and about 55:45 inclusive.

In a preferred embodiment, the polymer of formula (2) as described above is present in excess with respect to the polymer of formula (3) as previously described in the reaction medium.

In a particularly preferred embodiment, there is 10% by weight excess of polymer of formula (2) relative to the polymer of formula (3) in the reaction medium.

In a preferred embodiment, the silicone copolymers as described above are present in a cosmetic composition in an amount sufficient for said composition to form a film when it is applied to the skin.

The non-crosslinked cyclic silicone copolymers used according to the invention are present in the cosmetic composition at a concentration preferably of between approximately 0.1% and approximately 60% by weight relative to the total weight of the composition.

As described above, the silicone copolymers and the solvent (s) in which they are carried are in a cosmetically acceptable medium.

Cosmetically acceptable medium means a physiologically acceptable medium, that is to say compatible with the skin, and which does not produce feelings of discomfort (redness, tightness, tingling ...) unacceptable to the user after application on the skin.

The composition according to the invention may be in the form of an oil-in-water (O / W) emulsion, water-in-oil (W / O) such as a water-in-silicone emulsion (E / Si), or multiple (E / H / E, W / E / H, etc.). The composition according to the invention may also be anhydrous, that is to say that it contains no water or at most water naturally included in the ingredients it contains, that is to say say at most 3% by weight of water or even at most 1% by weight of water relative to the weight of the composition. It may, in particular, be in the form of a fluid product or in the form of a semisolid product such as a cream.

In addition to the uncrosslinked cyclic silicone copolymer, the composition used according to the invention may contain various adjuvants, such as at least one compound chosen from oils; waxes; lipophilic gelling agents; pasty compounds; film-forming polymers; emulsifiers; optical-effect compounds, including dyestuffs, such as fillers, optionally interferential pigments, water-soluble or fat-soluble dyes, lakes and nacres; tensors; antioxidants; UV filters; sequestering agents such as EDTA salts; pH adjusters; conservatives; perfumes ; and their mixtures, without this list being limiting.

In addition to the solvents described above, the oils may be chosen from (poly) esters and (poly) synthetic esters and in particular (poly) esters of C 6 -C 20 acids and of advantageously branched C 6 -C 20 alcohols, such as isononyl isononanoate or isostearyl neopentanoate, vegetable oils, branched and / or unsaturated fatty acids, branched and / or unsaturated fatty alcohols, fluorinated oils, and mixtures thereof.

It is understood that the composition according to the invention may comprise mixtures of the oils mentioned above.

The composition according to the invention may furthermore contain at least one polar wax chosen in particular from animal waxes, vegetable waxes, synthetic waxes containing polar groups such as esters and silicone waxes containing polar groups such as groups esters. Mention may thus be made of Carnauba, Candelilla, Bee (Cera alba), Chinese insect (Ericerus Pela), C8-C20 and Glycerin triesters such as glycerin tribehenate, acetylated glycol stearate marketed in particular by the company VEVY under the trade name CETACENE °, and mixtures thereof.

The composition according to the invention may also comprise apolar waxes such as, in particular, paraffin waxes, polymethylene waxes, polyethylene waxes or polybutene waxes, microcrystalline waxes, ozokerite, silicone waxes and mixtures thereof. It is preferred to use silicone waxes.

In addition, the composition according to the invention may contain at least one lipophilic gelling agent other than the uncrosslinked cyclic silicone copolymer of formula (1) described above. Examples of lipophilic gelling agents include silicone polymers and more particularly elastomers of organopolysiloxanes. Among these, mention may be made of at least partially crosslinked non-cyclic polymers resulting from the reaction of an organopolysiloxane bearing unsaturated groups, such as vinyl or allyl groups, located at the end or in the middle of the chain, preferably on a silicon atom, with another reactive silicone compound such as an organohydrogenpolysiloxane. These polymers are usually available in gel form in a volatile or nonvolatile silicone solvent or in a hydrocarbon solvent. Examples of such elastomers are in particular marketed by SHIN ETSU under the trade names KSG-6, KSG-16, KSG-31, KSG-32, KSG-41, KSG-420, KSG-43 and KSG-44, and by the company Dow Corning under the trade names DC 9040 and DC 9041. Another oily gelling agent consists of a silicone polymer obtained by self-polymerization of an organopolysiloxane functionalized with epoxy and hydrosilyl groups, in the presence of a catalyst, which is commercially available from the company General Electric under the trade name VELVESIL® 125. The lipophilic gelling agent may alternatively be a bentone or a sucrose ester such as that designated by the INCI name Sucrose tetrastearate triacetate.

The composition according to the invention may also contain one or more pasty compounds, that is to say lipophilic fatty substances which, like waxes, are capable of undergoing a reversible liquid / solid state change and have the solid state an anisotropic crystalline organization, but which differ from waxes in that they contain, at a temperature of 23 ° C, a liquid fraction and a solid fraction.

It may further comprise at least one film-forming polymer capable of providing hold and / or non-transfer properties to the makeup imparted by the composition. It may especially be a cyclic silicone copolymer optionally modified urethane or fluorinated or acrylate such as silicones (meth) acrylates sold by SHIN-ETSU under the trade names KP-5450, KP-561 and KP-562 °, or the polymers marketed by Dow Corning under the trade names DC FA 4002 ID and DC FA 4001 CM. Other examples of film-forming polymers are silicone resins and in particular MQ resins such as trimethylsiloxysilicates and MT resins such as silsesquioxane derivatives and in particular polymethylsilsesquioxanes, marketed in particular by SHIN-ETSU, and polypropylsilsesquioxane. marketed by the company Dow Corning under the trade name DC 670 or phenylpropyl polysilsesquioxane marketed by WACKER under the trade name BELSIL ° SPR45VP. Another example consists of fluorosilicone polymers identified by the INCI name trifluoropropyldimethylsiloxy triethylsiloxysilicate such as that sold by General Electric under the trade name XS66-B8226 °. It is also possible to use, as film-forming polymers, bioadhesive polymers obtained for example by polycondensation of dimethiconol and silicate resin MQ in a solvent such as heptane, which are sold, for example, by Dow Corning under the trade names DC 7-4405 low tack and DC 7-4505 high tack. Other examples of film-forming polymers are cyclic polyolefins such as polycyclopentadiene, sold especially by the company KOBO under the trade name KOBOGUARD 5400, or else polydicyclopentadiene. Still other examples of film-forming agents are copolymers of vinylpyrrolidone (VP) and / or of linear olefins such as the VP / hexadecene and VP / eicosene copolymers, including ANTARON V216 and ANTARON V220 from ISP or else ethylene / vinyl acetate copolymers such as AC 400 from the company BAERLOCHER. Other film-forming polymers which may be used in this invention are polyacrylates such as poly (ethyl acrylate) marketed in particular by CREATIONS COULEURS under the trade name CREASIL® 7 ID.

In the case where it is in the form of an emulsion, it is understood that the composition according to the invention may also contain one or more water-in-oil emulsifiers preferably chosen from nonionic surfactants, such as polyethoxylated dipolyhydroxystearate. (30 0E) marketed in particular under the trade name ARLACEL P135 by the company UNIQEMA; or the polysiloxanes modified with polyethers, and / or one or more oil-in-water emulsifiers chosen from nonionic surfactants such as optionally polyethoxylated sorbitan esters, esters of fatty acids and of glycerol, esters of fatty acids and sucrose, polyethylene glycol fatty acid esters, polyether modified polysiloxanes such as PEG-10 dimethicone sold under the trademark KF 6017 by Shin-Etsu and polyether modified silicone elastomers, alcohol ethers fatty acids and polyethylene glycol, alkylpolyglycosides and hydrogenated lecithin.

By fillers, it is necessary to include colorless or white particles, mineral or synthetic, lamellar or non-lamellar, intended to give body or stiffness to the composition and / or softness, dullness and uniformity immediately to the application. As fillers, there may be mentioned talc, mica, silica, kaolin, nylon powders such as nylon-12 for example, sold under the trademark Orgasol '° by the company Atochem, polyethylene powders, polyurethane powders, polystyrene powders, polyester powders, composite powders such as mica powder coated with aluminum hydroxide sold under the trademark Excel Mica JP2 "by the company Miyoshi Kasei, and optionally starch modified silicone resin microbeads such as, for example, those sold by Toshiba under the name Tospear1 °, hydroxyapatite, and hollow silica microspheres, for example, sold under the trademark Silica Beads "by the Company Maprecos.

By pigments, it is necessary to understand white or colored particles, mineral or organic, insoluble in the medium, intended to color and / or opacify the composition, of usual size or nanoscale. Among the inorganic pigments, there may be mentioned dioxides of titanium, zirconium or cerium, as well as oxides of zinc, iron or chromium.

By lakes is meant water-soluble dyes adsorbed on an inert mineral support.

By nacres or interferential pigments, we must understand iridescent particles that reflect light. Among the nacres that can be envisaged, mention may be made of natural mother-of-pearl, mica coated with titanium oxide, with iron oxide, with natural pigment or with bismuth oxychloride, and with colored titanium mica.

The mass concentration of these fillers and / or pigments and / or nacres is generally from 0.1% to 20%, and preferably from 0.2% to 7% by weight relative to the total weight of the composition. By tensor agents, it is necessary to understand compounds which may have a tensor effect, that is to say, which may tend the skin and, by this tension effect, smooth the skin and reduce or even eliminate wrinkles immediately. and fine lines. As tensors, mention may be made of polymers of natural origin and synthetic polymers.

By polymer of natural origin, is meant in particular polymers of plant origin. These polymers are preferably hydrophilic. Plant-based polymers that may especially be mentioned include proteins and protein hydrolysates, and more particularly extracts of cereals, legumes and oleaginous plants, such as extracts of corn, rye, wheat, buckwheat, sesame, spelled, pea, bean, lentil, soy and lupine.

The synthetic polymers are generally in the form of a latex or a pseudolatex and may be of the polycondensate type or radical type. Mention may in particular be made of the copolymer of PVP / dimethykylacrylate and of hydrophilic polyurethane marketed for example under the trademark Aquamere S-2011 by the company Hydromer.

The composition used according to the invention may further contain at least one UV filter selected from organic and inorganic filters and mixtures thereof. As organic filters, there may be mentioned in particular dibenzoylmethane derivatives (including butyl methoxydibenzoylmethane), cinnamic acid derivatives (including ethylhexyl methoxycinnamate), salicylates, para-aminobenzoic acids, (3, (3'- diphénylacrylates, benzophenones, benzylidene camphor derivatives, phenylbenzimidazoles, triazines, phenylbenzotriazoles and anthranilic derivatives As inorganic filters, there may be mentioned mineral oxide based filters in the form of pigments or nanopigments, coated or no, and in particular based on titanium dioxide or zinc oxide.

The composition used according to the invention may further comprise cosmetic active agents and in particular at least one active agent chosen from: agents stimulating the production of growth factors; anti-glycation or deglycating agents; agents that increase collagen synthesis or prevent its degradation (anti-collagenase agents, in particular inhibitors of matrix metalloproteinases); agents that enhance elastin synthesis or prevent its degradation (anti-elastase agents); agents that enhance the synthesis of glycosaminoglycans or proteoglycans or prevent their degradation; agents that increase the proliferation or differentiation of keratinocytes; agents increasing the proliferation of fibloblasts; depigmenting, anti-pigmenting or propigmenting agents; anti-oxidant or anti-radical agents or anti-pollution agents; agents increasing the synthesis of epidermal lipids; agents stimulating the expression of MT-SP1 matriptase; lipolysis stimulating agents, inhibiting lipogenesis and / or inhibiting adipocyte differentiation; draining or detoxifying agents or improving microcirculation; actins stimulating the expression of fructosamine-3-kinase (FN3K) or its related protein (FN3K RP); active agents capable of stimulating the expression of tensin 1; and their mixtures, without this list being limiting.

Examples of such additional active ingredients include plant extracts and in particular Hamamelis extracts and soy protein hydrolysates.

Examples of such adjuvants are cited in particular in the CTFA Dictionary (International Cosmetic Ingredient Dictionary and Handbook published by The Cosmetic, Toiletry and Fragrance Association, Heme Edition, 2006).

The composition used according to the invention can be considered as a skin foundation which makes it possible to guarantee a good resistance of the makeup compositions of the skin brought into contact with it.

It is understood that the makeup compositions of the skin may comprise the same adjuvants as those mentioned above in the composition according to the invention. The makeup composition of the skin is in particular a foundation, a concealer, a concealer and a powder such as in particular a two-way cake. Preferably, the makeup composition of the skin is a silicone continuous phase composition.

Furthermore, as described above for the composition used according to the invention, the makeup composition of the skin can be anhydrous or be in the form of oil-in-water (O / W) emulsion, water-in-oil (E / H) or multiple (E / H / E, H / E / H, etc.).

Generally, a foundation is designed to possibly succeed the application of a day cream and precede the application of at least one makeup composition of the skin such as a foundation.

In a preferred embodiment, the foundation of the invention is directly applied to the skin, thus preceding the application of at least one makeup composition of the skin.

According to another embodiment, the foundation of the invention is applied over at least one makeup composition of the skin.

Another object of the invention is a makeup kit comprising a cosmetic composition containing at least one uncrosslinked cyclic silicone copolymer as defined above and at least one skin makeup composition, each of the compositions being packaged separately. in different compartments. These different compositions are advantageously accompanied by suitable application means such as brushes, brushes, sponges and / or foam tips. The invention will now be illustrated by the following non-limiting examples which are given for purposes of illustration only and are not intended to limit the scope of the invention, which is defined by the appended claims. EXAMPLE

Skin Foundation, Water-in-Silicone Emulsion A skin base having the composition shown in Table 1 below was made in which the proportions of the ingredients are expressed in percentages by weight.

Table 1 INCI NAME / chemical name / Reference Quantity commercial function (%) pigments 9,61 ............... CYCLOPENTASILOXANE 4,80 CYCLOPENTASILOXANE & BIS-VINYL JEESILC ° PS-CM 8, 00 DIMETHICONE / DIMETHICONE COPOLYMER .............................

.................................................. PEG-10 DIMETHICONE KF 6017 7.20 DIMETHICONE DIMETHICONE ° 5 7.00..DTD: ............................. ................................... CYCLOMETHICONE CYCLOMETHICONE 5 8,00..DTD: ..... .................................................. ......... TOCOPHERYL ACETATE ACETATE OF DL2 0,20 TOCOPHEROL ..DTD: ............................ .................................... ETHYLHEXYL METHOXYCINNAMATE PARSOL MCX 7.50 CYCLOPENTASILOXANE & BENTONE GEL 3.00 DISTEARDIMONIUM HECTORITE & SD ALCOHOL 40 SILICON.VS5 V 1.00 1.00 nacres LAUROYL LYSINE AMIHOPE LL 3.00 preservatives 3.00 BUTYLENE GLYCOL 1.3 BUTYLENE 5.00 GLYCERIN GLYCOL 6.00 GLYCERINE ° SODIUM CHLORIDE SODIUM CHLORIDE 1.00 water RECTAPUR 17.19 WATER DEMINERALIZED perfume 0.50. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROLYZED SOY PROTEIN & BIODERMINE ° 3.00 PROPYLENE GLYCOL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . WITCH HAZEL DISTILLATE WITCH HAZEL (14 5.00 ETH.) This composition was prepared in a conventional manner known to those skilled in the art ... FT: USE OF A COSMETIC COMPOSITION COMPRISING A CYCLIC SILICONE COPOLYMER TO IMPROVE THE FIXATION OF MAKE-UP

Claims (9)

1. Use of a cosmetic composition containing, in a cosmetically acceptable medium, at least one non-crosslinked cyclic silicone copolymer and at least one solvent chosen from linear silicones, cyclic silicones, hydrocarbons and mixtures thereof, for improving the fixing and / or holding skin makeup compositions. 2. Use according to claim 1, characterized in that said uncrosslinked cyclic silicone copolymer is represented by the formula (1): ## STR2 ## in which z is an integer from 2 to 2000; A is a silicone silicone polymer of formula (2). Wherein Ak is an integer from 0 to 5000 and Ak is a C1-C6 alkyl such as methyl. and B is a divinyl-terminated silicone polymer of the formula (3). (1) at the ends of the disilane- (2) Ak Ak Ak 1 - (CH 2) -Si- (O-Si -) - O-Si- (CH 2) Wherein y is an integer from 0 to 5000 and Ak is a C1-C6 alkyl such as methyl. 3. Use according to claim 2, characterized in that x has a value between 5 and 200, preferably between 10 and 100, and even more preferably between 10 and 50. 4. Use according to claim 2, characterized in that y has a value between 5 and 200, preferably between 10 and 100, and even more preferably between 10 and 50. 15 5. Use according to any one of claims 1 to 4, characterized in that the uncrosslinked cyclic silicone copolymer is a bis-vinyl dimethicone / dimethicone copolymer and the solvent is cyclopentasiloxane. 6. Use according to any one of claims 1 to 5, characterized in that the uncrosslinked cyclic silicone copolymer is present in said cosmetic composition at a concentration of between about 0.1% and about 60% by weight relative to total weight of the composition. 7. Use according to any one of Claims 1 to 6, characterized in that the (3) cosmetic composition containing said uncrosslinked cyclic silicone copolymer is applied directly to the skin, thus preceeding the application of at least one composition. make-up of the skin. 8. Use according to any one of claims 1 to 7, characterized in that the cosmetic composition containing said uncrosslinked cyclic silicone copolymer is applied between a day cream and said at least one makeup composition of the skin. 9. Makeup kit comprising a cosmetic composition containing at least one uncrosslinked cyclic silicone copolymer as defined in claims 2 to 5; and at least one skin makeup composition, each of the compositions being packaged separately in different compartments.