FR2909293B1 - Micro-dispositif de traitement d'echantillons liquides - Google Patents
Micro-dispositif de traitement d'echantillons liquidesInfo
- Publication number
- FR2909293B1 FR2909293B1 FR0655327A FR0655327A FR2909293B1 FR 2909293 B1 FR2909293 B1 FR 2909293B1 FR 0655327 A FR0655327 A FR 0655327A FR 0655327 A FR0655327 A FR 0655327A FR 2909293 B1 FR2909293 B1 FR 2909293B1
- Authority
- FR
- France
- Prior art keywords
- micro
- processing liquid
- liquid samples
- samples
- processing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/302—Micromixers the materials to be mixed flowing in the form of droplets
- B01F33/3021—Micromixers the materials to be mixed flowing in the form of droplets the components to be mixed being combined in a single independent droplet, e.g. these droplets being divided by a non-miscible fluid or consisting of independent droplets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/40—Mixing liquids with liquids; Emulsifying
- B01F23/41—Emulsifying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B01F33/3031—Micromixers using electro-hydrodynamic [EHD] or electro-kinetic [EKI] phenomena to mix or move the fluids
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Fluid Mechanics (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Mechanical Engineering (AREA)
- Clinical Laboratory Science (AREA)
- Electrostatic Separation (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Micromachines (AREA)
- Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0655327A FR2909293B1 (fr) | 2006-12-05 | 2006-12-05 | Micro-dispositif de traitement d'echantillons liquides |
JP2009539723A JP5166436B2 (ja) | 2006-12-05 | 2007-12-03 | 液体サンプルを処理するためのマイクロデバイス |
US12/518,007 US8444836B2 (en) | 2006-12-05 | 2007-12-03 | Microdevice for treating liquid samples |
PCT/EP2007/063178 WO2008068229A1 (fr) | 2006-12-05 | 2007-12-03 | Micro-dispositif de traitement d'échantillons liquides. |
EP07847689A EP2097160B1 (fr) | 2006-12-05 | 2007-12-03 | Micro-dispositif et procédé de traitement d'échantillons liquides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0655327A FR2909293B1 (fr) | 2006-12-05 | 2006-12-05 | Micro-dispositif de traitement d'echantillons liquides |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2909293A1 FR2909293A1 (fr) | 2008-06-06 |
FR2909293B1 true FR2909293B1 (fr) | 2011-04-22 |
Family
ID=38198138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0655327A Expired - Fee Related FR2909293B1 (fr) | 2006-12-05 | 2006-12-05 | Micro-dispositif de traitement d'echantillons liquides |
Country Status (5)
Country | Link |
---|---|
US (1) | US8444836B2 (fr) |
EP (1) | EP2097160B1 (fr) |
JP (1) | JP5166436B2 (fr) |
FR (1) | FR2909293B1 (fr) |
WO (1) | WO2008068229A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109603939A (zh) * | 2019-01-04 | 2019-04-12 | 京东方科技集团股份有限公司 | 极板及微流控芯片 |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6911132B2 (en) | 2002-09-24 | 2005-06-28 | Duke University | Apparatus for manipulating droplets by electrowetting-based techniques |
US7329545B2 (en) * | 2002-09-24 | 2008-02-12 | Duke University | Methods for sampling a liquid flow |
CN101146595B (zh) | 2005-01-28 | 2012-07-04 | 杜克大学 | 用于在印刷电路板上操作液滴的装置和方法 |
US8734003B2 (en) * | 2005-09-15 | 2014-05-27 | Alcatel Lucent | Micro-chemical mixing |
US20140193807A1 (en) | 2006-04-18 | 2014-07-10 | Advanced Liquid Logic, Inc. | Bead manipulation techniques |
US8637324B2 (en) | 2006-04-18 | 2014-01-28 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
US8658111B2 (en) | 2006-04-18 | 2014-02-25 | Advanced Liquid Logic, Inc. | Droplet actuators, modified fluids and methods |
WO2009140671A2 (fr) | 2008-05-16 | 2009-11-19 | Advanced Liquid Logic, Inc. | Dispositifs et procédés actionneurs de gouttelettes pour manipuler des billes |
US7439014B2 (en) | 2006-04-18 | 2008-10-21 | Advanced Liquid Logic, Inc. | Droplet-based surface modification and washing |
US10078078B2 (en) | 2006-04-18 | 2018-09-18 | Advanced Liquid Logic, Inc. | Bead incubation and washing on a droplet actuator |
US8809068B2 (en) | 2006-04-18 | 2014-08-19 | Advanced Liquid Logic, Inc. | Manipulation of beads in droplets and methods for manipulating droplets |
WO2007123908A2 (fr) | 2006-04-18 | 2007-11-01 | Advanced Liquid Logic, Inc. | Opérations en puits multiples à base de gouttelettes |
US8716015B2 (en) | 2006-04-18 | 2014-05-06 | Advanced Liquid Logic, Inc. | Manipulation of cells on a droplet actuator |
US9675972B2 (en) | 2006-05-09 | 2017-06-13 | Advanced Liquid Logic, Inc. | Method of concentrating beads in a droplet |
WO2008091848A2 (fr) * | 2007-01-22 | 2008-07-31 | Advanced Liquid Logic, Inc. | Chargement de fluide assisté en surface et distribution de gouttelette |
CA2712863C (fr) | 2007-02-09 | 2015-01-06 | Advanced Liquid Logic, Inc. | Dispositifs actionneurs de gouttelettes et procedes employant des perles magnetiques |
WO2008101194A2 (fr) | 2007-02-15 | 2008-08-21 | Advanced Liquid Logic, Inc. | Détection de capacité sur un actuateur goutte |
US8268246B2 (en) | 2007-08-09 | 2012-09-18 | Advanced Liquid Logic Inc | PCB droplet actuator fabrication |
WO2009032863A2 (fr) | 2007-09-04 | 2009-03-12 | Advanced Liquid Logic, Inc. | Actionneur de gouttelette avec substrat supérieur amélioré |
US20100236928A1 (en) * | 2007-10-17 | 2010-09-23 | Advanced Liquid Logic, Inc. | Multiplexed Detection Schemes for a Droplet Actuator |
WO2009052321A2 (fr) * | 2007-10-18 | 2009-04-23 | Advanced Liquid Logic, Inc. | Actionneurs de gouttelettes, systèmes et procédés |
MX2010007034A (es) * | 2007-12-23 | 2010-09-14 | Advanced Liquid Logic Inc | Configuraciones para eyector de gotas y metodos para realizar operaciones de gota. |
FR2930457B1 (fr) * | 2008-04-24 | 2010-06-25 | Commissariat Energie Atomique | Procede de fabrication de microcanaux reconfigurables |
WO2009137415A2 (fr) | 2008-05-03 | 2009-11-12 | Advanced Liquid Logic, Inc. | Réactif et préparation, charge et stockage d'échantillon |
FR2936167A1 (fr) * | 2008-09-23 | 2010-03-26 | Commissariat Energie Atomique | Micro-dispositif d'analyse d'echantillons liquides. |
US8877512B2 (en) | 2009-01-23 | 2014-11-04 | Advanced Liquid Logic, Inc. | Bubble formation techniques using physical or chemical features to retain a gas bubble within a droplet actuator |
US20130146459A1 (en) * | 2009-06-16 | 2013-06-13 | Massachusetts Institute Of Technology | Multiphase non-linear electrokinetic devices |
US8926065B2 (en) | 2009-08-14 | 2015-01-06 | Advanced Liquid Logic, Inc. | Droplet actuator devices and methods |
WO2011057197A2 (fr) | 2009-11-06 | 2011-05-12 | Advanced Liquid Logic, Inc. | Actionneur de gouttelettes intégré pour électrophorèse sur gel et analyse moléculaire |
EP2516669B1 (fr) | 2009-12-21 | 2016-10-12 | Advanced Liquid Logic, Inc. | Analyses d'enzymes sur un diffuseur à gouttelettes |
WO2011126892A2 (fr) | 2010-03-30 | 2011-10-13 | Advanced Liquid Logic, Inc. | Plateforme pour opérations sur des gouttelettes |
EP2588322B1 (fr) | 2010-06-30 | 2015-06-17 | Advanced Liquid Logic, Inc. | Ensembles actionneurs à gouttelettes et leurs procédés de fabrication |
JP5822953B2 (ja) * | 2011-02-11 | 2015-11-25 | コミサリア ア レネルジィ アトミーク エ オ ゼネ ルジイ アルテアナティーフCommissariata L’Energie Atomique Et Aux Energies Alternatives | 液滴中に存在する検体を検出するための方法およびマイクロシステム |
TWI419738B (zh) * | 2011-03-18 | 2013-12-21 | Ind Tech Res Inst | 微粒子輸送器 |
EP2707131B1 (fr) | 2011-05-09 | 2019-04-24 | Advanced Liquid Logic, Inc. | Rétroaction microfluidique utilisant une détection d'impédance |
EP2707724A4 (fr) | 2011-05-10 | 2015-01-21 | Advanced Liquid Logic Inc | Concentration d'enzymes et dosages |
CA2840949A1 (fr) | 2011-07-06 | 2013-01-10 | Advanced Liquid Logic Inc | Stockage de reactifs sur un actionneur de manipulation de gouttelettes |
US8901043B2 (en) | 2011-07-06 | 2014-12-02 | Advanced Liquid Logic, Inc. | Systems for and methods of hybrid pyrosequencing |
WO2013009927A2 (fr) | 2011-07-11 | 2013-01-17 | Advanced Liquid Logic, Inc. | Actionneurs de gouttelettes et techniques pour dosages à base de gouttelettes |
US9446404B2 (en) | 2011-07-25 | 2016-09-20 | Advanced Liquid Logic, Inc. | Droplet actuator apparatus and system |
CA2854023A1 (fr) | 2011-11-07 | 2013-05-16 | Illumina, Inc. | Appareils de sequencage integre et procedes d'utilisation |
FR2982176B1 (fr) * | 2011-11-09 | 2014-01-10 | Commissariat Energie Atomique | Dispositif et procede de manipulation des gouttes |
US10731199B2 (en) | 2011-11-21 | 2020-08-04 | Advanced Liquid Logic, Inc. | Glucose-6-phosphate dehydrogenase assays |
RU2489202C1 (ru) * | 2012-04-27 | 2013-08-10 | Владимир Иванович Клешканов | Мелкодисперсная эмульсия на основе воды и водонерастворимых веществ и способ ее получения |
US9223317B2 (en) | 2012-06-14 | 2015-12-29 | Advanced Liquid Logic, Inc. | Droplet actuators that include molecular barrier coatings |
BR112014032727B1 (pt) | 2012-06-27 | 2021-12-14 | Illumina France | Método e sistema para realizar operações de gotícula em uma gotícula em um atuador de gotículas para redução da formação de bolhas |
US9863913B2 (en) | 2012-10-15 | 2018-01-09 | Advanced Liquid Logic, Inc. | Digital microfluidics cartridge and system for operating a flow cell |
CN105435664B (zh) * | 2014-09-12 | 2018-06-29 | 杭州华安生物技术有限公司 | 一种抗原乳化器 |
CN104275115A (zh) * | 2014-09-30 | 2015-01-14 | 博奥赛斯(天津)生物科技有限公司 | 一种免疫抗原预处理方法 |
JP5825618B1 (ja) * | 2015-02-06 | 2015-12-02 | 秋田県 | 電界撹拌用電極及びこれを用いた電界撹拌方法 |
EP3093647A1 (fr) * | 2015-05-14 | 2016-11-16 | Consorci Centre de Recerca Matematica | Procédé, appareil et micro-rhéomètre permettant de mesurer les propriétés rhéologiques de fluides non newtoniens et newtoniens |
US11061015B2 (en) * | 2015-08-28 | 2021-07-13 | Sharp Life Science (Eu) Limited | Droplet microfluidic device and methods of sensing the results of an assay therein |
CN109126917B (zh) * | 2018-10-09 | 2020-04-10 | 京东方科技集团股份有限公司 | 微流控芯片及其驱动方法 |
US11460020B2 (en) * | 2019-02-19 | 2022-10-04 | MicroMED Co., Ltd. | Micro-delivery device |
CN111920395B (zh) * | 2020-07-22 | 2024-04-09 | 上海掌门科技有限公司 | 一种脉搏采集装置 |
CN116585756B (zh) * | 2023-07-19 | 2023-09-22 | 山东第一医科大学附属省立医院(山东省立医院) | 一种适用于单分子采样设备及样本存储装置 |
US12104989B1 (en) | 2024-01-11 | 2024-10-01 | Shandong Provincial Hospital | Sampling device and sample storage device suitable for single molecule |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6565727B1 (en) * | 1999-01-25 | 2003-05-20 | Nanolytics, Inc. | Actuators for microfluidics without moving parts |
FR2829576B1 (fr) | 2001-09-12 | 2003-10-31 | Bio Merieux | Procede et dispositif d'isolement et/ou determination d'un analyte |
US6545815B2 (en) * | 2001-09-13 | 2003-04-08 | Lucent Technologies Inc. | Tunable liquid microlens with lubrication assisted electrowetting |
FR2837401B1 (fr) | 2002-03-25 | 2004-12-03 | Commissariat Energie Atomique | Procede de concentration de macromolecules ou agglomerats de molecules ou particules |
US7147763B2 (en) * | 2002-04-01 | 2006-12-12 | Palo Alto Research Center Incorporated | Apparatus and method for using electrostatic force to cause fluid movement |
CN100478075C (zh) * | 2003-11-17 | 2009-04-15 | 皇家飞利浦电子股份有限公司 | 用于操纵流体实体的系统 |
US7267752B2 (en) * | 2004-07-28 | 2007-09-11 | University Of Rochester | Rapid flow fractionation of particles combining liquid and particulate dielectrophoresis |
US8685216B2 (en) * | 2004-12-21 | 2014-04-01 | Palo Alto Research Center Incorporated | Apparatus and method for improved electrostatic drop merging and mixing |
-
2006
- 2006-12-05 FR FR0655327A patent/FR2909293B1/fr not_active Expired - Fee Related
-
2007
- 2007-12-03 EP EP07847689A patent/EP2097160B1/fr active Active
- 2007-12-03 US US12/518,007 patent/US8444836B2/en active Active
- 2007-12-03 JP JP2009539723A patent/JP5166436B2/ja active Active
- 2007-12-03 WO PCT/EP2007/063178 patent/WO2008068229A1/fr active Application Filing
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109603939A (zh) * | 2019-01-04 | 2019-04-12 | 京东方科技集团股份有限公司 | 极板及微流控芯片 |
CN109603939B (zh) * | 2019-01-04 | 2021-08-31 | 京东方科技集团股份有限公司 | 极板及微流控芯片 |
Also Published As
Publication number | Publication date |
---|---|
JP2010511506A (ja) | 2010-04-15 |
US8444836B2 (en) | 2013-05-21 |
EP2097160A1 (fr) | 2009-09-09 |
US20100320088A1 (en) | 2010-12-23 |
FR2909293A1 (fr) | 2008-06-06 |
EP2097160B1 (fr) | 2013-04-03 |
WO2008068229A1 (fr) | 2008-06-12 |
JP5166436B2 (ja) | 2013-03-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20160831 |