FR2898046A1 - Topical composition useful for cleaning, as make up remover, care and/or make up of skin and to treat acne, comprises alpha hydroxy acids and beta hydroxy acids, and fatty alcohol, in the form of oil-in-water emulsion - Google Patents

Abstract

Topical composition comprises active acid such as alpha hydroxy acids and beta hydroxy acids, and a fatty alcohol such as 12-30 carbon alcohol and having a fusion point of >=45[deg]C, in the form of oil-in-water emulsion, an oil phase dispersed in an aqueous phase. ACTIVITY : Antiseborrheic; Dermatological. MECHANISM OF ACTION : None given. No biological data given.

Description

Emulsion containing hydroxy acids

  The invention relates to an oil-in-water emulsion (O / W) containing hydroxy acids, and to its use in the cosmetic or dermatological field, in particular for cleaning, removing make-up, care and / or makeup of materials. keratin, especially the skin and mucous membranes, and for the treatment of acne.

  It is known to use in cosmetic or dermatological compositions, acidic active agents such as α-hydroxy acids such as glycolic acid and lactic acid, and 3-hydroxy acids such as salicylic acid. These active ingredients are used especially for the care of the face and / or the body and more especially to give the face a luminous and radiant complexion and therefore a good appearance, a smooth and younger appearance, to treat the wrinkles and fine lines of the skin. , to depigment the skin and in particular to remove the spots that appear with aging, as well as to treat oily skin, and to eliminate comedones caused by acne. The properties of these active ingredients can also make it interesting to incorporate them into cleaning compositions.

  These active agents, which can be incorporated into various dosage forms such as emulsions, solutions, gels, are generally used in small amounts, for example less than 1% of the total weight of the composition. Their incorporation in small quantities does not usually pose too many problems. However, when it is desired to incorporate them in larger amounts, for example at 2% by weight or more, especially in O / W emulsions and for example in O / W emulsions thickened with partially or totally neutralized fatty acids, they cause a destabilization of the emulsion which is out of phase (separation of part of the oily phase), and this even in the presence of polymers usually used to gel emulsions.

  There remains therefore the need for a stable composition in the form of an oil-in-water emulsion, usable in particular in the cosmetic and / or dermatological fields, and allowing a sufficient incorporation of the acidic active agents generally used in these fields, while keeping a good stability.

  The Applicant has surprisingly found that the use of fatty alcohols having a melting point of greater than 45 ° C makes it possible to obtain thick and stable O / W emulsions in the presence of these acidic active agents, even in large quantities, and for example equal to or greater than 2% by weight.

  Thus, the subject of the invention is a composition for topical application, in the form of an oil-in-water emulsion, comprising an oily phase dispersed in an aqueous phase, characterized in that it comprises at least one acidic active agent chosen from the α-hydroxy acids and the 3-hydroxy acids, and at least one fatty alcohol chosen from alcohols containing from 12 to 30 carbon atoms and having a melting point equal to or greater than 45 ° C.

  Since the cosmetic composition is intended for topical application, it comprises a physiologically acceptable medium. In the present application, the term "physiologically acceptable medium" means a medium that is compatible with all keratin materials such as the skin, the nails, the mucous membranes, the eyes or any other cutaneous zone of the body. The composition may especially be a cosmetic or dermatological composition, more especially a composition for the skin.

  The composition according to the invention may, depending on the case, be rinsed or not rinsed.

  The composition of the invention is in the form of a cream, that is to say a flexible product as opposed to a solid product such as a stick. This cream can be more or less fluid. Thus, this composition can have a viscosity at 25 ° C ranging from about 10 to 220 poise (1 to 22 Pa. $) And preferably from about 15 to 200 poise (1.5 to 20 Pa. $), This viscosity being measured with a Rheomat 180 at 25 C with the appropriate mobiles.

  The composition according to the invention generally has a pH of less than 6, in particular equal to or less than 5, and in practice chosen in the range from 1 to 5, preferably from 2 to 5 and better still from 3 to 5.

  Owing to the presence of the fatty alcohol with a melting point of 45 ° C. or higher, the composition obtained is stable, even in the presence of at least 2% by weight of α-hydroxy acids and / or 3- hydroxy acids, even more, for example 3% by weight and even 4% of α-hydroxy acids and / or 13-hydroxy acids.

  The term "stable composition" is intended to mean a composition in which the aqueous and oily phases remain emulsified one inside the other, and do not phase out by separating.

  In the present application, fatty alcohol is understood to mean an alcohol comprising a fatty chain, that is to say a chain having from 12 to 30 carbon atoms.

  Acidic Acid The composition contains at least one acid active agent chosen from α-hydroxy acids and 3-hydroxy acids. The α-hydroxy acids that can be used in the composition of the invention are acids comprising at least one -C (OH) -COOH group, especially mono-acids, diacids or triacids. Ketoacids such as vitamin C are excluded from this definition. These α-hydroxy acids are compounds of formula (I): ## STR2 ## in which R 1 and R 2, independently of one another, can be chosen from H, CH 3, CHOHCOOH, CH 2 OOH, COOH, CH 2 OH ( CHOH) X where x is an integer from 1 to 6, C6H5.

  According to a preferred embodiment of the invention, the α-hydroxy acids that can be used in the composition of the invention are chosen from citric acid, lactic acid, glycolic acid, gluconic acid and tartaric acid. , malic acid, and mixtures thereof, as well as plant extracts containing them, in particular fruit extracts.

  As 3-hydroxy-acids that can be used in the composition of the invention, mention may be made, for example, of salicylic acid and its derivatives, in particular its alkylated derivatives, that is to say its derivatives of formula (II): COOH in which: - R, represents a hydroxyl radical or an ester of formula:

20 -O-CO-R4

  in which R 4 is a saturated or unsaturated aliphatic radical comprising from 1 to 26 carbon atoms, and preferably from 1 to 18 carbon atoms, an amine or thiol functional group optionally substituted by an alkyl radical comprising from 1 to 18 atoms of carbon, and preferably 1 to 12 carbon atoms, - R2 and R3 independently of each other are in position 3, 4, 5 or 6 on the benzene ring and independently represent one of the other a hydrogen atom or a radical: ## STR2 ## wherein n and m, independently of each other, are each an integer of 0 or 1; with the proviso that R2 and R3 are not simultaneously hydrogen atoms; R 5 represents a hydrogen, a saturated aliphatic radical comprising from 1 to 18 carbon atoms, linear, branched or cyclized, an unsaturated radical comprising from 3 to 18 carbon atoms, bearing one to nine conjugated or non-conjugated double bonds, the radicals; which may be substituted by at least one substituent chosen from halogen atoms (fluorine, chlorine, bromine, iodine), trifluoromethyl radicals, hydroxyl in free form or esterified with an acid 40 comprising from 1 to 6 carbon atoms, or carboxyl free or esterified with a lower alcohol having 1 to 6 carbon atoms, an aromatic radical comprising 6 to 10 carbon atoms. The preferred salicylic acid derivatives of formula (II) are those in which R 1 represents a hydroxyl radical R2 represents a hydrogen atom, R3 is at the 5-position of the benzene ring and R5 represents a saturated aliphatic radical comprising from 3 to 15 carbon atoms.

  When the composition contains a salicylic acid derivative of formula (II), it may be in particular n-octanoyl-5-salicylic acid, n-decanoyl-5-salicylic acid, n-dodecanoyl-5-salicylic acid, n -octyl-5-salicylic, n-heptyloxy-5-salicylic, n-heptyloxy-4-salicylic, 5-tert-octylsalicylic, 3-tert-butyl-5-methylsalicylic, 3-tert-butyl-6-methylsalicylic, 3 , 5-diisopropylsalicylic, 5-butoxysalicylic, 5-octyloxysalicylic, 5-propanoyl-salicylic, n-hexadecanoyl-5-salicylic, 5-neryl-5-salicylic, 5-benzoyl salicylic, their monovalent and divalent salts and mixtures thereof. It is preferably n-octanoyl-5-salicylic acid (INCI name: Capryloyl Salicylic acid).

  According to a preferred embodiment of the invention, when the composition contains a p-hydroxy acid, it is preferably salicylic acid.

  The amount of α-hydroxy acids and 33-hydroxy acids may be less than 2% by weight, but the invention is particularly advantageous when the ahydroxy acids and the 3-hydroxy acids are present in an amount ranging for example from 2 to 20% by weight. preferably 2 to 10%, more preferably 3 to 10% by weight, more preferably 4 to 8% by weight and preferably 4 to 7% by weight relative to the total weight of the composition.

  Fatty alcohol having a melting point equal to or greater than 45 ° C. The fatty alcohol is chosen from alcohols containing from 12 to 30 carbon atoms and preferably from 14 to 24 carbon atoms, and which have an equal melting point. or higher (pF) at 45 C.

  The fatty alcohol may in particular be chosen from cetyl alcohol (pF = 475), stearyl alcohol (pF = 61 ° C.) and their mixtures such as cetearyl alcohol (pF = 48 ° C.).

  The composition may contain one or more fatty alcohols, and the amount of fatty alcohol (s) may range, for example, from 0.1 to 15% by weight, preferably from 0.5 to 10% by weight, more preferably 1 to 10% by weight, more preferably 1 to 8% by weight and more preferably 2 to 6% by weight relative to the total weight of the composition.

  Emulsifier The composition according to the invention preferably contains at least one emulsifier. All known emulsifiers for the preparation of O / W emulsions can be used in the composition of the invention. Preferably, the composition contains at least one nonionic emulsifier. Examples of nonionic emulsifiers that may be mentioned include oxyalkylenated fatty acid and polyol esters, more particularly oxyethylenated fatty acid and polyol esters comprising, for example, from 20 to 150 oxyethylenated units 50 (OE), and for example polyethylene glycol stearates such as PEG-100 stearate, PEG-50 stearate and PEG-40 stearate; esters of oxyalkylenated and especially oxyethylenated fatty acids and of sorbitan comprising, for example, from 20 to 100 OE, and for example Polysorbates (INCI name) such as Polysorbate 60; oxyalkylenated and especially oxyethylenated or oxypropylenated fatty alcohol ethers, such as oxyethylenated stearyl alcohol ethers (INCI name: Steareth) such as Steareth-21, and oxypropylene-containing stearyl alcohol ethers (INCI name: PPG Stearyl ether) such as PPG-15 stearyl ether; sugar esters such as sucrose stearate; oxyalkylenated and especially oxyethylenated sugar ethers such as polyoxyethylenated methyl glucose ethers (INCI name: Methyl Gluceth) such as methyl gluceth-20; and mixtures containing them, for example the mixture of glyceryl stearate and PEG-100 stearate (INCI name: Glyceryl S / PEG-100 Stearate) sold under the name Arlacel 165 by Uniqema or under the name Simulsol 165 by the company SEPPIC.

  According to a preferred embodiment of the invention, the composition contains at least one emulsifier chosen from oxyethylenated stearyl alcohol ethers, oxyethylenated fatty acid and sorbitan esters, stearyl alcohol ethers which are oxypropylenated, ethers of oxyethylenated sugar, and mixtures thereof. The emulsifier may in particular be chosen from polysorbates, methyl gluceths, PPG stearyl ethers, steareths and mixtures thereof.

  In a more particularly preferred embodiment, the composition contains as emulsifiers a mixture of Polysorbate 60, methyl gluceth-20, PPG-5 stearyl ether and Steareth-20.

  The composition may contain one or more emulsifiers. The amount of emulsifier (s) may range, for example, from 0.1 to 15% by weight, preferably from 1 to 10% by weight, better still from 2 to 10% by weight and even more preferably from 3 to 10% by weight. weight relative to the total weight of the composition.

  Oily phase The oily phase of the composition according to the invention may represent, for example, from 1 to 50% by weight, preferably from 1 to 40% by weight, better still from 2 to 30% by weight and even more preferably from 3 to 25% by weight. % by weight relative to the total weight of the composition.

  The oily phase may consist only of the fatty alcohols of the composition, but it may further comprise fatty alcohols other than those of pF equal to or greater than 45 C, and also any compounds which are already generally known to be suitable for the manufacture of oil-in-water emulsions, in the cosmetic or dermatological fields.

  As fatty alcohols other than those of pF equal to or greater than 45 ° C., mention may be made, for example, of fatty alcohols having from 12 to 30 carbon atoms and having a melting point of less than 45 ° C., such as lauryl alcohol, myristic alcohol, oleic alcohol, hexyldecanol. In addition to the fatty alcohols, the oily phase may contain one or more oils. Among the oils that may be included in the composition of the oily phase, there may be mentioned: hydrocarbon-based oils of animal origin, such as perhydrosqualene; hydrocarbon oils of plant origin such as sweet almond oil, black currant oil, borage oil, hemp oil, avocado oil, castor oil, coriander oil, olive oil, jojoba oil, sesame oil, peanut oil, grapeseed oil, rapeseed oil, coconut oil , hazelnut oil, shea butter, palm oil, apricot kernel oil, calophyllum oil, rice bran oil, corn germ oil, lemon wheat germ oil, soybean oil, sunflower oil, evening primrose oil, safflower oil, passion flower oil, rye oil, triglycerides of caprylic acids / capric such as those sold by the company Stearineries Dubois or those sold under the names Miglyol 810, 812 and 818 by the company Dynamit Nobel; esters and synthetic ethers, in particular of fatty acids, such as the oils of formulas R'COOR2 and R'OR2 in which R 'represents the residue of a fatty acid containing from 8 to 29 carbon atoms, and R2 represents a hydrocarbon chain, branched or unbranched, containing from 3 to 30 carbon atoms, for example Purcellin oil, isononyl isononanoate, isopropyl myristate, 2-ethylhexyl palmitate, octyl-2-dodecyl stearate, octyl-2-dodecyl erucate, isostearyl isostearate; hydroxylated esters such as isostearyl lactate, octyl hydroxystearate, octyldodecyl hydroxystearate, diisostearyl malate, triisocetyl citrate, heptanoates, octanoates, decanoates of fatty alcohols; polyol esters, such as propylene glycol dioctanoate, neopentyl glycol diheptanoate and diethylene glycol diisononanoate; pentaerythritol esters such as pentaerythritol tetraisostearate; dicaprylic ether (CTFA name: Dicaprylyl ether); benzoates of C12-C15 fatty alcohols (Finsolv TN of FIN ETEX); substantially linear or branched hydrocarbons of mineral or synthetic origin, such as mineral oils (CTFA name: Minerai Oil), petroleum jelly oil such as those sold under the Marcol 82, Marcol 52, Marcol 172 and Primol brands 352 by the company Esso, paraffin oils, volatile or not, their derivatives, and mixtures thereof; polydecenes, isohexadecane, isododecane, isoparaffins and poly-α-olefins, hydrogenated polyisobutene such as Parleam oil; fluorinated and perfluorinated oils; volatile or nonvolatile silicone oils, such as volatile or nonvolatile polymethylsiloxanes (PDMS) with a linear or cyclic silicone chain, which are liquid or pasty at room temperature. There may be mentioned in particular volatile silicone oils such as cyclopolydimethylsiloxanes (cyclomethicones) such as cyclohexasiloxane; polydimethylsiloxanes comprising alkyl, alkoxy or phenyl groups, during or at the end of the silicone chain, groups having from 2 to 24 carbon atoms; phenyl silicones such as phenyltrimethicones, phenyldimethicones, phenyltrimethylsiloxydiphenylsiloxanes, diphenyldimethicones, diphenylmethyldiphenyltrisiloxanes, 2-phenylethyltrimethylsiloxysilicates and polymethylphenylsiloxanes.

  By hydrocarbon oil is meant in the list of oils mentioned above, any oil predominantly comprising carbon and hydrogen atoms, and optionally ester, ether, fluoro, carboxylic acid and / or alcohol groups.

  Aqueous phase The aqueous phase of the composition of the invention is generally present in an amount ranging from 50 to 99%, preferably from 60 to 99%, better still from 70 to 98% by weight and even more preferably from 75 to 97% by weight. by weight relative to the total weight of the composition.

  In a conventional manner, the aqueous phase may contain, in addition to water, one or more water-soluble solvents chosen from polyols (or polyhydric alcohols), water-soluble lower alcohols (s) and mixtures thereof. By "lower alcohol" is meant an alcohol having 1 to 8 carbon atoms. Lower alcohols include, for example, ethanol, isopropanol, butanol and mixtures thereof.

  Examples of polyols that may be mentioned include glycerine; glycols such as propylene glycol, butylene glycol; sorbitol; sugars such as glucose, fructose, maltose, lactose, sucrose; and their mixtures. The amount of solvents (lower alcohols and polyols) can range, for example, from 0.5 to 30% by weight, preferably from 0.5 to 20% by weight, and better still from 1 to 15% by weight relative to the total weight. of the composition.

  The composition according to the invention may also contain any adjuvant or additive usually used in the cosmetic or dermatological fields.

  Among the conventional adjuvants which may be present in the aqueous phase and / or in the oily phase of the emulsions according to the invention (according to the water-soluble or fat-soluble nature of these adjuvants), mention may be made in particular of cosmetic or dermatological active agents, hydrophilic or lipophilic, other than the acids indicated above; the perfumes ; conservatives ; sequestering agents (EDTA); pigments; mother-of-pearl; mineral or organic fillers; soluble dyes; solar filters; alkanizing or acidifying agents; polymers; and their mixtures. The amounts of these various adjuvants are those conventionally used in the field under consideration, and for example from 0.01 to 20% of the total weight of the composition.

  Of course, those skilled in the art will take care to choose the optional compound (s) to be added to the composition according to the invention in such a way that the advantageous properties intrinsically attached to the composition according to the invention are not, or substantially not, altered by the intended addition.

  As polymers, one or more hydrophilic or lipophilic gelling agents may be incorporated in the composition in particular. The hydrophilic gelling agents, that is to say those which are soluble or dispersible in water, can be chosen, for example, from modified or unmodified carboxyvinyl polymers, such as the products sold under the names Carbopol (INCI name: carbomer) and Pemulen ( INCI name: Acrylates / C10-30 akyl acrylate crosspolymer) by the company 50 Noveon; polyacrylamides; polymers and copolymers of 2-acrylamido-2-methylpropanesulphonic acid (AMPS), optionally cross-linked and / or neutralized, such as poly (2-acrylamido-2-methylpropanesulphonic acid) marketed by the company Hoechst under the name Hostacerin AMPS (name INCI ammonium polyacryldimethyltauramide); crosslinked anionic copolymers of acrylamide and of AMPS, in the form of an W / O emulsion, such as those marketed under the name SEPIGEL 305 (CTFA name Polyacrylamide / C13-14 Isoparaffin / Laureth-7) and the name SIMULGEL 600 (CTFA name: Acrylamide / Sodium acryloyldimethyltaurate copolymer / Isohexadecane / Polysorbate 80) by the company SEPPIC; polysaccharide biopolymers such as guar gum, alginates, modified or unmodified celluloses; and their mixtures. These gelling agents may be present in an amount ranging, for example, from 0.001 to 5% by weight, preferably from 0.05 to 5% by weight and better still from 0.1 to 3% by weight relative to the total weight of the composition.

  The composition may also contain fillers, and especially exfoliating fillers when the composition is intended to be a scrubbing product.

  As fillers, mention may be made, for example, of polyamide (nylon) particles and in particular those sold under the names ORGASOL by the company Atochem; polyethylene powders; microspheres based on acrylic copolymers, such as those made of ethylene glycol dimethacrylate / lauryl methacrylate copolymer sold by Dow Corning under the name Polytrap; polymethyl methacrylate microspheres, sold under the name MICROSPHERE M-100 by the company Matsumoto or under the name COVABEAD LH85 by the company Wackherr; ethylene-acrylate copolymer powders, such as those sold under the name FLOBEADS by Sumitomo Seika Chemicals; expanded powders such as hollow microspheres and in particular microspheres formed of a terpolymer of vinylidene chloride, acrylonitrile and methacrylate and sold under the name EXPANCEL by the company Kemanord Plast under the references 551 DE 12 (particle size distribution). about 12 lm and density 40 kg / m3), 551 DE 20 (particle size of about 30 lm and density 65 kg / m3), 551 DE 50 (particle size of about 40 m), or the microspheres marketed under the name MICROPEARL F 80 ED by the company Matsumoto; powders of natural organic materials such as starch powders, especially corn starch, wheat or rice, crosslinked or otherwise, such as starch powders crosslinked with octenylsuccinate anhydride, sold under the name DRY -FLO by the company National Starch silicone resin microbeads such as those sold under the name Tospearl by Toshiba Silicone, including Tospearl 240; silica; metal oxides such as titanium dioxide or zinc oxide; mica; and their mixtures. The amount of filler (s) may range, for example, from 0.05 to 20% by weight and better still from 0.1 to 10% by weight relative to the total weight of the composition.

  As exfoliating fillers, it is possible to use all the exfoliating particles of mineral, vegetable or organic origin, usually used in the cosmetic field. The exfoliant fillers may, for example, be chosen from water-swellable powdery polymers (powder or beads), polyethylene particles (balls or powders), jojoba spheres, shells from crushed fruit cores, and pumice stone. glass beads, aluminum oxide, and mixtures thereof.

  The composition according to the invention can be used in many cosmetic or dermatological applications where the presence of α-hydroxy acids and / or 13-hydroxy acids is useful. This composition may especially be used for cleaning and / or removing make-up from the skin of the face and / or the body, for the care and / or makeup of the skin of the face and / or the body, the mucous membranes (lips).

  In the care, it can be used for example to give the face a bright and radiant complexion, a good-looking, a smooth and younger look, to treat wrinkles and fine lines of the skin, to depigment the skin and in particular to remove stains aging, and to remove comedones.

  Thus, the compositions of the invention may constitute a skin care product, a product for cleaning and / or removing make-up from the skin, a skin-scrubbing product. They can also be used for peels.

  They may also constitute makeup products, especially for makeup of the skin, lips and / or nails. They can more particularly constitute a foundation.

  The compositions of the invention can also be used as a solar product to protect the skin from UV rays. Thus, the present invention also relates to the cosmetic use of the cosmetic composition according to the invention, for cleaning and / or removing make-up. of the skin of the face and / or the body, for the care and / or makeup of the skin of the face and / or the body, and the lips. Another object of the invention is a method of cosmetic treatment of the skin, characterized in that a cosmetic composition is applied to the skin, as defined above. The composition is applied according to the usual technique of use of this composition according to the desired purpose. The type of treatment is a function of the acid (s) present in the composition.

  The acids present in the composition, in particular salicylic acid, may optionally be used for the treatment of acne. The composition can therefore also be used to treat acne. The invention further relates to a use of the composition defined above for preparing an ointment or ointment for treating acne.

  Example according to the invention and Comparative Example 45 The following example illustrates the invention without being limiting in nature. Quantities are given as percentage by weight unless otherwise indicated. The compounds are indicated in INCI name or in chemical name. Example Example according to the invention tif Phase A Polysorbate 60 0.5 0.5 PPG-15 Stearyl Ether 3.5 3.5 Steareth-21 3 3 Stearic Acid - 10 Cetyl Alcohol 4 4 Stearyl Alcohol 4 - Phase B Water qs 100% qs 100% Phase C Glycolic acid 4 4 Salicylic acid 2 2 Water 10 10 Glycerine 5 5 Methyl Gluceth-20 2 2 Phase D Ammonium Polyacryloyldimethyl 1 1 taurate (Hostacerin AMPS) Phase E Sodium hydroxide 1,1 1, Triethanolamine 1.9 1.9 Phase F Preservatives 0.6 0.6 Procedure: Phase E in phase B was introduced with stirring at a temperature of about 60 ° C., then phase C was added. Then, phase D was added to the mixture, and the emulsion was made by adding phase A to the previously obtained mixture at a temperature of about 80 ° C. After cooling to room temperature, the phase was added. F. Then, it was allowed to cool with stirring until it returned to room temperature (about 20 to 25 ° C).

  The above two examples are compositions of pH 4.1, pH well tolerated by the skin.

  The example of the invention is in the form of a cream which can be used for example for the cleansing of oily skin. It can be used for example on wet skin massage, then it is rinsed with water. Rinsing is very easy.

  At zero time, the comparative example is also in the form of a cream, but after 2 months in an oven at 45 C, it is out of phase (destabilization), while the example according to the invention remained stable. 20

Claims (15)

  1. Composition for topical application, in the form of an oil-in-water emulsion, comprising an oily phase dispersed in an aqueous phase, characterized in that it comprises at least one acidic active agent chosen from α-hydroxy acids and 3-hydroxy acids, and at least one fatty alcohol selected from alcohols having from 12 to 30 carbon atoms and having a melting point equal to or greater than 45 C.   2. Composition according to claim 1, characterized in that the hydroxy acids are compounds of formula: ## STR2 ## in which R 1 and R 2, independently of one another, can be chosen from H, CH 3, CHOHCOOH, CH2OOOH, COOH, CH2OH (CHOH) X where x is an integer from 1 to 6, C6H5   3. Composition according to claim 1 or 2, characterized in that the α-hydroxy acids are chosen from citric acid, lactic acid, glycolic acid, gluconic acid, tartaric acid and malic acid. , and mixtures thereof, as well as plant extracts containing them.   4. Composition according to any one of the preceding claims, characterized in that the 3-hydroxy-acids are chosen from salicylic acid and its alkylated derivatives, and mixtures thereof.   5. Composition according to any one of the preceding claims, characterized in that the amount of active acid (s) acid (s) ranges from 2 to 20% by weight relative to the total weight of the composition.   6. Composition according to any one of the preceding claims, characterized in that the fatty alcohol is chosen from cetyl alcohol, stearyl alcohol and mixtures thereof.   7. Composition according to any one of the preceding claims, characterized in that the amount of fatty alcohol (s) ranges from 0.1 to 15% by weight relative to the total weight of the composition. 40   8. Composition according to any one of the preceding claims, characterized in that it contains at least one nonionic emulsifier.   9. Composition according to the preceding claim, characterized in that the nonionic emulsifier is chosen from oxyethylenated stearyl alcohol ethers, oxyethylenated fatty acid and sorbitan esters, ethers of stearyl alcohol oxypropylene, ethers of oxyethylenated sugar, and mixtures thereof.   10. Composition according to claim 8 or 9, characterized in that the amount of emulsifier (s) ranges from 0.1 to 15% by weight relative to the total weight of the composition)   11. Composition according to any one of the preceding claims, characterized in that the oily phase represents from 1 to 50% by weight relative to the total weight of the composition.   12. Composition according to any one of the preceding claims, characterized in that it constitutes a skin care product, a product for cleaning and / or removing makeup from the skin, a skin peeling product, a product makeup, a solar product. 13 Cosmetic use of a cosmetic composition according to any one of claims 1 to 11, for cleaning and / or removing makeup from the skin of the face and / or the body, for the care and / or makeup of the skin of the skin. face and / or body, and lips. 14. Cosmetic treatment process of the skin, characterized in that a cosmetic composition according to any one of Claims 1 to 11 is applied to the skin. 15. Use of the composition according to any one of claims 1 to 11, for preparing an ointment or ointment for treating acne.