FR2887241B1 - Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation - Google Patents

Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation

Info

Publication number
FR2887241B1
FR2887241B1 FR0506063A FR0506063A FR2887241B1 FR 2887241 B1 FR2887241 B1 FR 2887241B1 FR 0506063 A FR0506063 A FR 0506063A FR 0506063 A FR0506063 A FR 0506063A FR 2887241 B1 FR2887241 B1 FR 2887241B1
Authority
FR
France
Prior art keywords
physical
flow device
chemical transformation
determining parameters
microfluidic flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0506063A
Other languages
English (en)
Other versions
FR2887241A1 (fr
Inventor
Galder Cristobal
Armand Ajdari
Mathieu Joanicot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhodia Chimie SAS
Original Assignee
Rhodia Chimie SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Chimie SAS filed Critical Rhodia Chimie SAS
Priority to FR0506063A priority Critical patent/FR2887241B1/fr
Priority to AT06764795T priority patent/ATE474663T1/de
Priority to US11/922,337 priority patent/US7919323B2/en
Priority to DE602006015637T priority patent/DE602006015637D1/de
Priority to PCT/FR2006/001361 priority patent/WO2006134274A1/fr
Priority to EP06764795A priority patent/EP1890803B1/fr
Publication of FR2887241A1 publication Critical patent/FR2887241A1/fr
Application granted granted Critical
Publication of FR2887241B1 publication Critical patent/FR2887241B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/81—Forming mixtures with changing ratios or gradients
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/0086—Dimensions of the flow channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00968—Type of sensors
    • B01J2219/0097—Optical sensors
    • B01J2219/00972—Visible light
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00968—Type of sensors
    • B01J2219/0097—Optical sensors
    • B01J2219/00977—Infrared light
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00984—Residence time
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
FR0506063A 2005-06-15 2005-06-15 Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation Expired - Fee Related FR2887241B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR0506063A FR2887241B1 (fr) 2005-06-15 2005-06-15 Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation
AT06764795T ATE474663T1 (de) 2005-06-15 2006-06-15 Mikrofluidikzirkulationsvorrichtung zur bestimmung von parametern einer physikalischen und/oder chemischen transformation und verwendung davon
US11/922,337 US7919323B2 (en) 2005-06-15 2006-06-15 Microfluidic flow devices for determining parameters of physical and/or chemical transformations
DE602006015637T DE602006015637D1 (de) 2005-06-15 2006-06-15 Mikrofluidikzirkulationsvorrichtung zur bestimmung von parametern einer physikalischen und/oder chemischen transformation und verwendung davon
PCT/FR2006/001361 WO2006134274A1 (fr) 2005-06-15 2006-06-15 Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation
EP06764795A EP1890803B1 (fr) 2005-06-15 2006-06-15 Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0506063A FR2887241B1 (fr) 2005-06-15 2005-06-15 Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation

Publications (2)

Publication Number Publication Date
FR2887241A1 FR2887241A1 (fr) 2006-12-22
FR2887241B1 true FR2887241B1 (fr) 2008-01-11

Family

ID=35677587

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0506063A Expired - Fee Related FR2887241B1 (fr) 2005-06-15 2005-06-15 Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation

Country Status (1)

Country Link
FR (1) FR2887241B1 (fr)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US5872010A (en) * 1995-07-21 1999-02-16 Northeastern University Microscale fluid handling system
ATE291225T1 (de) * 1995-12-05 2005-04-15 Gamera Bioscience Corp Vorrichtung und verfahren zum bewegen von fluiden mittels zentrifugalbeschleunigung bei der automatischen laborbehandlung
US6709869B2 (en) * 1995-12-18 2004-03-23 Tecan Trading Ag Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
GB2319771B (en) * 1996-11-29 2001-09-26 Imperial College Process
US5869004A (en) * 1997-06-09 1999-02-09 Caliper Technologies Corp. Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems
US6601613B2 (en) * 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
DE10218280C1 (de) * 2002-04-19 2003-11-20 Fraunhofer Ges Forschung Integriertes Misch- und Schaltsystem für die Mikroreaktionstechnik
EP1391237B1 (fr) * 2002-08-01 2011-09-21 Tosoh Corporation Dispositif avec des canaux minces, installation chimique miniaturisé pour la production de particules fineset dispositif employantant les dites particules
JPWO2005049196A1 (ja) * 2003-11-21 2007-12-27 株式会社荏原製作所 液体を用いたマイクロチップ装置

Also Published As

Publication number Publication date
FR2887241A1 (fr) 2006-12-22

Similar Documents

Publication Publication Date Title
IL264748B (en) Devices, methods and operators for testing
WO2009083975A3 (fr) Dispositifs d'analyse de petites molécules et de protéines à partir de polymères à empreintes moléculaires
HK1070690A1 (zh) 用於確定化驗結果的流體感測
FR2865307B1 (fr) Dispositif de determination du risque de collision
WO2006122310A3 (fr) Systeme d'essai
EP1803805A4 (fr) Récipient de réaction, dispositif d'introduction de liquide pour recipient de reaction, dispositif d'introduction de liquide et de mesure de reaction, et dispositif d'introduction de liquide
EP1772102A4 (fr) Instrument de mesure de la forme d"un vaisseau sanguin, instrument de mesure de la vitesse du débit sanguin et appareil de mesure du débit sanguin
BRPI0814088A2 (pt) Dispositivo sensor magnético, uso do mesmo, chip sensor magnético, método para determinar a presença e/ou quantidade de porções alvo em um fluido de amostra, e, produto de programa de computador
EP1873522A4 (fr) Méthode de détermination d'un dérivé d'hémoglobine, et composition de réactif, kit de dosage, dispositif d'analyse et système d'analyse utilisés dans ladite méthode
ES1060753Y (es) "dispositivo de control y valoracion de acciones deportivas".
HK1129808A2 (en) Reversed flow through platform for rapid analysis of target analytes with increased sensitivity and specificity and the device thereof
ITFI20060310A1 (it) Dispositivo portatile per la misura ed il controllo di analiti in fluidi biologici.
AU2002364120A8 (en) Sensor for the use in testing biological chemical or environmental samples
FR2884702B1 (fr) Dispositif pour evaluer l'aptitude physique d'un individu
EP1990634A4 (fr) Puce de biocapteur, systeme de biocapteur et leur dispositif de mesure
ITRN20030024A1 (it) Dispositivo per il prelievo di campioni biologici e/o chimici.
FR2903886B1 (fr) Dispositif d'etirement de la colonne vertebrale d'une personne
FR2887241B1 (fr) Dispositif d'ecoulement microfluidique permettant de determiner des parametres d'une transformation physique et/ou chimique, et son utilisation
WO2004010143A3 (fr) Dispositifs electrochimiques a ecoulement lateral et a ecoulement continu
FR2883855B3 (fr) Dispositif de deplacement pour skieurs ou surfeurs des neiges
ATE474663T1 (de) Mikrofluidikzirkulationsvorrichtung zur bestimmung von parametern einer physikalischen und/oder chemischen transformation und verwendung davon
FR2897156B1 (fr) Procede de determination d'au moins un parametre d'une transformation physique et/ou chimique, dispositif et installation correspondants
AU2003304256A1 (en) An online flow through microchip for detecting hazardous chemical and biological agents in drinking water
FR2864625B1 (fr) Procede et installation de determination des caracteristiques representatives d'une transformation physique et/ou chimique intervenant dans un micro-reacteur
FR2871071B1 (fr) Dispositif de traitement chimique de l'eau, notamment de traitement anti-tartre

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20150227