FR2882151B1 - Procede de detection des interactions entre un recepteur couple aux proteines g(rcpg) et l'une des sous-unites galpha ou galpha/gamma d'une proteine g - Google Patents

Procede de detection des interactions entre un recepteur couple aux proteines g(rcpg) et l'une des sous-unites galpha ou galpha/gamma d'une proteine g

Info

Publication number
FR2882151B1
FR2882151B1 FR0501485A FR0501485A FR2882151B1 FR 2882151 B1 FR2882151 B1 FR 2882151B1 FR 0501485 A FR0501485 A FR 0501485A FR 0501485 A FR0501485 A FR 0501485A FR 2882151 B1 FR2882151 B1 FR 2882151B1
Authority
FR
France
Prior art keywords
galpha
protein
gpcr
coupled receptor
gamma subunits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0501485A
Other languages
English (en)
Other versions
FR2882151A1 (fr
Inventor
Herve Ansanay
Michel Fink
Gerard Mathis
Damien Maurel
Eric Trinquet
Jean Philippe Pin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
CIS Bio International SA
Original Assignee
Centre National de la Recherche Scientifique CNRS
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, CIS Bio International SA filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR0501485A priority Critical patent/FR2882151B1/fr
Priority to JP2007554620A priority patent/JP2008534917A/ja
Priority to EP06709506A priority patent/EP1849003A1/fr
Priority to PCT/FR2006/050127 priority patent/WO2006085040A1/fr
Publication of FR2882151A1 publication Critical patent/FR2882151A1/fr
Application granted granted Critical
Publication of FR2882151B1 publication Critical patent/FR2882151B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4719G-proteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
FR0501485A 2005-02-14 2005-02-14 Procede de detection des interactions entre un recepteur couple aux proteines g(rcpg) et l'une des sous-unites galpha ou galpha/gamma d'une proteine g Expired - Fee Related FR2882151B1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR0501485A FR2882151B1 (fr) 2005-02-14 2005-02-14 Procede de detection des interactions entre un recepteur couple aux proteines g(rcpg) et l'une des sous-unites galpha ou galpha/gamma d'une proteine g
JP2007554620A JP2008534917A (ja) 2005-02-14 2006-02-13 Gタンパク質に結合する受容体(RCPG)とGタンパク質のGα又はGβγサブユニットの内の1つとの相互作用の検出方法
EP06709506A EP1849003A1 (fr) 2005-02-14 2006-02-13 Procede de detection des interactions entre un recepteur couple aux proteines g (rcpg) et l' une des sous-unites galpha ou galpha/gamma d' une proteine g
PCT/FR2006/050127 WO2006085040A1 (fr) 2005-02-14 2006-02-13 Procede de detection des interactions entre un recepteur couple aux proteines g (rcpg) et l' une des sous-unites galpha ou galpha/gamma d' une proteine g

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0501485A FR2882151B1 (fr) 2005-02-14 2005-02-14 Procede de detection des interactions entre un recepteur couple aux proteines g(rcpg) et l'une des sous-unites galpha ou galpha/gamma d'une proteine g

Publications (2)

Publication Number Publication Date
FR2882151A1 FR2882151A1 (fr) 2006-08-18
FR2882151B1 true FR2882151B1 (fr) 2007-06-08

Family

ID=34955471

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0501485A Expired - Fee Related FR2882151B1 (fr) 2005-02-14 2005-02-14 Procede de detection des interactions entre un recepteur couple aux proteines g(rcpg) et l'une des sous-unites galpha ou galpha/gamma d'une proteine g

Country Status (4)

Country Link
EP (1) EP1849003A1 (fr)
JP (1) JP2008534917A (fr)
FR (1) FR2882151B1 (fr)
WO (1) WO2006085040A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3069644A1 (fr) * 2017-07-28 2019-02-01 Cisbio Bioassays Methode pour mesurer la modulation de l'activation d'un recepteur couple a une proteine g

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004072608A2 (fr) * 2003-02-05 2004-08-26 Washington University In St. Louis Biocapteur et son utilisation afin d'identifier des molecules de medicaments therapeutiques et recepteurs orphelins de fixation de molecules

Also Published As

Publication number Publication date
JP2008534917A (ja) 2008-08-28
WO2006085040A1 (fr) 2006-08-17
FR2882151A1 (fr) 2006-08-18
EP1849003A1 (fr) 2007-10-31

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20141031