FR2860230B1 - NOVEL PROCESS FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE - Google Patents

NOVEL PROCESS FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE

Info

Publication number
FR2860230B1
FR2860230B1 FR0311225A FR0311225A FR2860230B1 FR 2860230 B1 FR2860230 B1 FR 2860230B1 FR 0311225 A FR0311225 A FR 0311225A FR 0311225 A FR0311225 A FR 0311225A FR 2860230 B1 FR2860230 B1 FR 2860230B1
Authority
FR
France
Prior art keywords
octahydro
isoindole
novel process
preparing cis
cis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0311225A
Other languages
French (fr)
Other versions
FR2860230A1 (en
Inventor
Rimane Aoun
Christian Bruneau
Pierre Dixneuf
Jean Luc Renaud
Jean Claude Souvie
Claude Fugier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Priority to FR0311225A priority Critical patent/FR2860230B1/en
Priority to PCT/FR2004/002414 priority patent/WO2005030719A1/en
Publication of FR2860230A1 publication Critical patent/FR2860230A1/en
Application granted granted Critical
Publication of FR2860230B1 publication Critical patent/FR2860230B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procédé de synthèse du cis-octahydro-isoindole à partir de phtalimide.Application à la synthèse de l'acide 2-(S)-benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)-butyrique, de ses sels pharmaceutiquement acceptables et de ses hydrates.Process for the synthesis of cis-octahydro-isoindole from phthalimide. Application to the synthesis of 2- (S) -benzyl-4-oxo-4- (cis-perhydroisoindol-2-yl) -butyric acid, its pharmaceutically acceptable salts and its hydrates.

FR0311225A 2003-09-25 2003-09-25 NOVEL PROCESS FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE Expired - Fee Related FR2860230B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0311225A FR2860230B1 (en) 2003-09-25 2003-09-25 NOVEL PROCESS FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE
PCT/FR2004/002414 WO2005030719A1 (en) 2003-09-25 2004-09-24 Novel method for preparing cis-octahydro-isoindole

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0311225A FR2860230B1 (en) 2003-09-25 2003-09-25 NOVEL PROCESS FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE

Publications (2)

Publication Number Publication Date
FR2860230A1 FR2860230A1 (en) 2005-04-01
FR2860230B1 true FR2860230B1 (en) 2006-01-21

Family

ID=34307153

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0311225A Expired - Fee Related FR2860230B1 (en) 2003-09-25 2003-09-25 NOVEL PROCESS FOR PREPARING CIS-OCTAHYDRO-ISOINDOLE

Country Status (2)

Country Link
FR (1) FR2860230B1 (en)
WO (1) WO2005030719A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100441570C (en) * 2006-05-24 2008-12-10 严洁 Preparation of mitiglinide calcium and its quality control method
CN102424664B (en) * 2011-11-04 2013-11-13 无锡福祈制药有限公司 Preparation method of mitiglinide calcium
CN103450070B (en) * 2013-08-13 2015-06-24 张家港威胜生物医药有限公司 Synthesis process of xylylenimine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3077442B2 (en) * 1993-02-19 2000-08-14 新日本理化株式会社 Method for producing cyclic amines
JPH10218858A (en) * 1997-02-03 1998-08-18 Sagami Chem Res Center Production of hexahydrophthalimidine

Also Published As

Publication number Publication date
FR2860230A1 (en) 2005-04-01
WO2005030719A1 (en) 2005-04-07

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Legal Events

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Effective date: 20070531