FR2837490B1 - Nouveaux derives de bisphosphonates, leurs preparations et utilisations - Google Patents
Nouveaux derives de bisphosphonates, leurs preparations et utilisationsInfo
- Publication number
- FR2837490B1 FR2837490B1 FR0203540A FR0203540A FR2837490B1 FR 2837490 B1 FR2837490 B1 FR 2837490B1 FR 0203540 A FR0203540 A FR 0203540A FR 0203540 A FR0203540 A FR 0203540A FR 2837490 B1 FR2837490 B1 FR 2837490B1
- Authority
- FR
- France
- Prior art keywords
- bisphosphonates
- preparations
- novel derivatives
- derivatives
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4025—Esters of poly(thio)phosphonic acids
- C07F9/404—Esters of poly(thio)phosphonic acids containing hydroxy substituents in the hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/386—Polyphosphonic acids containing hydroxy substituents in the hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4025—Esters of poly(thio)phosphonic acids
- C07F9/405—Esters of poly(thio)phosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/40—Esters thereof
- C07F9/4071—Esters thereof the ester moiety containing a substituent or a structure which is considered as characteristic
- C07F9/409—Compounds containing the structure P(=X)-X-acyl, P(=X) -X-heteroatom, P(=X)-X-CN (X = O, S, Se)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0203540A FR2837490B1 (fr) | 2002-03-21 | 2002-03-21 | Nouveaux derives de bisphosphonates, leurs preparations et utilisations |
ES02764988T ES2336312T3 (es) | 2001-07-16 | 2002-07-16 | Procedimiento de preparacion de derivados de bisfosfonatos. |
EP02764988A EP1406910B1 (fr) | 2001-07-16 | 2002-07-16 | Procedes de preparation de derives de bisphosphonates |
JP2003513984A JP4220382B2 (ja) | 2001-07-16 | 2002-07-16 | 新しいビスホスホナート誘導体、その製造法及び使用 |
PCT/FR2002/002526 WO2003008425A1 (fr) | 2001-07-16 | 2002-07-16 | Nouveaux derives de bisphosphonates, leurs preparations et utilisations |
AT02764988T ATE455121T1 (de) | 2001-07-16 | 2002-07-16 | Herstellungsverfahren von derivate von bisphosphonaten |
CA002451881A CA2451881A1 (fr) | 2001-07-16 | 2002-07-16 | Nouveaux derives de bisphosphonates, leurs preparations et utilisations |
DE60235085T DE60235085D1 (de) | 2001-07-16 | 2002-07-16 | Herstellungsverfahren von derivate von bisphosphonaten |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0203540A FR2837490B1 (fr) | 2002-03-21 | 2002-03-21 | Nouveaux derives de bisphosphonates, leurs preparations et utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2837490A1 FR2837490A1 (fr) | 2003-09-26 |
FR2837490B1 true FR2837490B1 (fr) | 2009-04-17 |
Family
ID=27799147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0203540A Expired - Fee Related FR2837490B1 (fr) | 2001-07-16 | 2002-03-21 | Nouveaux derives de bisphosphonates, leurs preparations et utilisations |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2837490B1 (fr) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69023844T2 (de) * | 1989-09-06 | 1996-06-20 | Merck & Co Inc | Acyloxymethylester der Bisphonsäuren als Knochenresorptions-Inhibitoren. |
FI89366C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
FI89364C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya, farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
WO1999051613A1 (fr) * | 1998-04-03 | 1999-10-14 | Medivir Ab | Promedicaments de produits pharmaceutiques contenant du phosphore |
ATE385797T1 (de) * | 1999-12-03 | 2008-03-15 | Univ California At San Diego | Phosphonatverbindungen |
-
2002
- 2002-03-21 FR FR0203540A patent/FR2837490B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2837490A1 (fr) | 2003-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |
Effective date: 20141128 |