FR2823307B1 - PROCESS AND MICROPRESSES FOR CHARACTERIZING THE MECHANICAL PROPERTIES OF PHARMACEUTICAL SOLIDS - Google Patents

PROCESS AND MICROPRESSES FOR CHARACTERIZING THE MECHANICAL PROPERTIES OF PHARMACEUTICAL SOLIDS

Info

Publication number
FR2823307B1
FR2823307B1 FR0104885A FR0104885A FR2823307B1 FR 2823307 B1 FR2823307 B1 FR 2823307B1 FR 0104885 A FR0104885 A FR 0104885A FR 0104885 A FR0104885 A FR 0104885A FR 2823307 B1 FR2823307 B1 FR 2823307B1
Authority
FR
France
Prior art keywords
micropresses
characterizing
mechanical properties
pharmaceutical solids
solids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0104885A
Other languages
French (fr)
Other versions
FR2823307A1 (en
Inventor
Didier Bielawsli
Guy Couarraze
Bernard Leclerc
Pierre Tchoreloff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DIGIPHARM
Original Assignee
DIGIPHARM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DIGIPHARM filed Critical DIGIPHARM
Priority to FR0104885A priority Critical patent/FR2823307B1/en
Priority to PCT/FR2002/001239 priority patent/WO2002084254A1/en
Publication of FR2823307A1 publication Critical patent/FR2823307A1/en
Application granted granted Critical
Publication of FR2823307B1 publication Critical patent/FR2823307B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/40Investigating hardness or rebound hardness
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N3/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N3/20Investigating strength properties of solid materials by application of mechanical stress by applying steady bending forces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/0077Testing material properties on individual granules or tablets
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/0058Kind of property studied
    • G01N2203/0076Hardness, compressibility or resistance to crushing
    • G01N2203/0078Hardness, compressibility or resistance to crushing using indentation
    • G01N2203/0082Indentation characteristics measured during load
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2203/00Investigating strength properties of solid materials by application of mechanical stress
    • G01N2203/02Details not specific for a particular testing method
    • G01N2203/0202Control of the test
    • G01N2203/0208Specific programs of loading, e.g. incremental loading or pre-loading

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Strength Of Materials By Application Of Mechanical Stress (AREA)
FR0104885A 2001-04-10 2001-04-10 PROCESS AND MICROPRESSES FOR CHARACTERIZING THE MECHANICAL PROPERTIES OF PHARMACEUTICAL SOLIDS Expired - Fee Related FR2823307B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0104885A FR2823307B1 (en) 2001-04-10 2001-04-10 PROCESS AND MICROPRESSES FOR CHARACTERIZING THE MECHANICAL PROPERTIES OF PHARMACEUTICAL SOLIDS
PCT/FR2002/001239 WO2002084254A1 (en) 2001-04-10 2002-04-09 Method and micro-press for characterising mechanical properties of pharmaceutical solids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0104885A FR2823307B1 (en) 2001-04-10 2001-04-10 PROCESS AND MICROPRESSES FOR CHARACTERIZING THE MECHANICAL PROPERTIES OF PHARMACEUTICAL SOLIDS

Publications (2)

Publication Number Publication Date
FR2823307A1 FR2823307A1 (en) 2002-10-11
FR2823307B1 true FR2823307B1 (en) 2003-09-26

Family

ID=8862171

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0104885A Expired - Fee Related FR2823307B1 (en) 2001-04-10 2001-04-10 PROCESS AND MICROPRESSES FOR CHARACTERIZING THE MECHANICAL PROPERTIES OF PHARMACEUTICAL SOLIDS

Country Status (2)

Country Link
FR (1) FR2823307B1 (en)
WO (1) WO2002084254A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006049813B4 (en) 2006-10-17 2009-01-22 Petrotest Instruments Gmbh & Co.Kg Method for determining the degree of hardness of semi-solid materials
FR2953291B1 (en) 2009-11-30 2017-01-20 Univ Rennes PORTABLE INSTRUMENTAL INDENTATION DEVICE
CN103808578B (en) * 2014-01-21 2016-02-10 河南科技大学 A kind of vacuum high-temperature high-speed friction abrasion test device
CN104729911B (en) * 2015-03-11 2017-04-26 吉林大学 In-situ micro-nano indentation/scratch test method
CN104897459B (en) * 2015-06-23 2018-03-30 北京航空航天大学 A kind of multidirectional loading system for particulate matter mechanical test
CN105203418B (en) * 2015-10-15 2017-08-29 郑州轻工业学院 Air-driven type cereal-granules hardness detecting instrument
CN106827649A (en) * 2017-02-10 2017-06-13 宁夏百辰工业产品设计有限公司 Friction press bidirectional operation stroke dislocation control assembly
CN109049793A (en) * 2018-06-22 2018-12-21 中国石油天然气股份有限公司 Experiment oil-sand compactor
WO2020079699A1 (en) * 2018-10-16 2020-04-23 M.O Advanced Technologies (Moat) Ltd Apparatus and method for prediction of tablet defects propensity
RU2696070C1 (en) * 2018-12-07 2019-07-30 Федеральное государственное бюджетное образовательное учреждение высшего образования "Тверской государственный технический университет" Device for creation and measurement of destructive load
CN110208107A (en) * 2019-06-19 2019-09-06 上海华龙测试仪器有限公司 A kind of electronic universal tester
CN111157380B (en) * 2020-02-25 2022-06-21 五邑大学 Hardness measurement device and method
CN111220476B (en) * 2020-03-23 2022-04-15 浙江义宇仪器设备有限公司 Testing machine for compression testing
CN112098201B (en) * 2020-07-21 2023-05-02 浙江定盘星智能科技有限公司 Gate-type mechanics testing mechanism and gate-type mechanics testing machine
CN116929973B (en) * 2023-09-18 2023-11-21 江苏润鼎智能装备科技有限公司 Aerated concrete body hardness detection device
CN117432896B (en) * 2023-12-20 2024-02-23 湖南千智机器人科技发展有限公司 Device and method for detecting surface of object to be detected

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5067346A (en) * 1986-07-10 1991-11-26 Commonwealth Scientific And Industrial Research Organization Penetrating measuring instrument
US4820051A (en) * 1986-08-21 1989-04-11 Nec Corporation Apparatus for determining microhardness
US4807465A (en) * 1988-02-19 1989-02-28 Warner-Lambert Company Apparatus for measuring capsule plug, granule and pellet hardness
US4957003A (en) * 1989-09-08 1990-09-18 The Upjohn Company Slow strain rate shear strength tester for compact
US5090249A (en) * 1990-08-08 1992-02-25 Jerzy Bielewicz Apparatus and method for testing the mechanical properties of a sample
US5140861A (en) * 1991-05-03 1992-08-25 The Upjohn Company Multifunction tablet tester
US5483836A (en) * 1994-10-13 1996-01-16 U.S. Army Corps Of Engineers As Represented By The Secretary Of The Army Device for measuring lateral deformations in material test specimens
US5616857A (en) * 1996-01-25 1997-04-01 Instron Corporation Penetration hardness tester
DE29711490U1 (en) * 1997-07-01 1998-01-08 Moser Markus Dr Rer Nat Universal measuring device for non-destructive stiffness tests for tablets
CA2306275C (en) * 1999-04-23 2009-11-03 Bio Syntech Canada Inc. Universal mechanical testing device
US6460399B1 (en) * 2000-11-14 2002-10-08 Genencor International, Inc. Compression test method and apparatus for determining granule strength

Also Published As

Publication number Publication date
WO2002084254A1 (en) 2002-10-24
FR2823307A1 (en) 2002-10-11

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Effective date: 20081231