FR2791893A1 - Use of grapefruit seed extract obtained by washing and grinding the seeds and extracting them with a solvent, in cosmetic, dermatological, food and agricultural compositions - Google Patents

Use of grapefruit seed extract obtained by washing and grinding the seeds and extracting them with a solvent, in cosmetic, dermatological, food and agricultural compositions Download PDF

Info

Publication number
FR2791893A1
FR2791893A1 FR9904765A FR9904765A FR2791893A1 FR 2791893 A1 FR2791893 A1 FR 2791893A1 FR 9904765 A FR9904765 A FR 9904765A FR 9904765 A FR9904765 A FR 9904765A FR 2791893 A1 FR2791893 A1 FR 2791893A1
Authority
FR
France
Prior art keywords
food
cosmetic
dermopharmaceutical
grapefruit seed
seed extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR9904765A
Other languages
French (fr)
Other versions
FR2791893B1 (en
Inventor
Frank Champagnat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PROD HYG LAB
Original Assignee
PROD HYG LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PROD HYG LAB filed Critical PROD HYG LAB
Priority to FR9904765A priority Critical patent/FR2791893B1/en
Publication of FR2791893A1 publication Critical patent/FR2791893A1/en
Application granted granted Critical
Publication of FR2791893B1 publication Critical patent/FR2791893B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis

Abstract

New cosmetic, dermatological, food and agricultural compositions contain an extract of grapefruit seeds.

Description

La présente invention concerne les applications pour le traitement et leThe present invention relates to applications for the treatment and

soin du corps, destinés à l'homme ou à l'animal, en application topique ou orale, contenant des extraits de pépins de pamplemousse. Ces applications sont plus  body care, intended for humans or animals, applied topically or orally, containing grapefruit seed extracts. These apps are more

particulièrement destinées aux effets amincissants, anti-inflammatoires, anti-  particularly intended for slimming, anti-inflammatory, anti

oxydant, nutritionnel. L'extraction des actifs du pépin de pamplemousse étaient jusqu'à présent essentiellement axée sur les huiles essentielles. L'objet de ces nouvelles propriétés très spécifiques se prêtent bien à la préparation de produits des industries cosmétiques, dermopharmaceutiques, diététiques, agro-alimentaires et  oxidizing, nutritional. The extraction of the active ingredients of the grapefruit seed were until now mainly focused on essential oils. The subject of these new very specific properties lend themselves well to the preparation of products from the cosmetic, dermopharmaceutical, dietetic, agrifood and

io agricoles destinées pour l'homme et à l'animal.  io agricultural intended for the man and the animal.

L'extrait est obtenu à partir du pépin de pamplemousse préalablement lavé et broyé. Son extraction dans un solvant sélectionné permet d'obtenir un liquide aqueux, glycolique, glycérine, alcoolique, hydroglycolique, hydroglycériné, hydroalcoolique. Ce liquide peut être utilisé tel quel, déshydraté partiellement pour obtenir un extrait mou ou totalement déshydraté pour obtenir un extrait sec. Le produit peut se conserver seul de part sa composition, son mode de filtration, son passage dans un système de décontamination ou additionné de conservateurs en  The extract is obtained from the grapefruit seed previously washed and ground. Its extraction in a selected solvent makes it possible to obtain an aqueous, glycolic, glycerin, alcoholic, hydroglycolic, hydroglycerine, hydroalcoholic liquid. This liquid can be used as it is, partially dehydrated to obtain a soft extract or completely dehydrated to obtain a dry extract. The product can be kept alone due to its composition, its filtration mode, its passage through a decontamination system or added with preservatives in

phases avec la législation de son domaine d'application.  phases with the legislation of its field of application.

L'analyse biochimique de l'extrait de pépin de pamplemousse révèle la présence d'hétérosides flavoniques, hétérosides coumariniques, terpènes et acides aminés. Des mesures quali-quantitatifs on permis de doser des flavonoïdes  Biochemical analysis of the grapefruit seed extract reveals the presence of flavonic heterosides, coumarin heterosides, terpenes and amino acids. Quali-quantitative measurements allowed to dose flavonoids

de type: eriocitrine, narirutine, naringine, hespéridine et néohespéridine.  type: eriocitrine, narirutin, naringin, hesperidin and neohesperidin.

Des produits semblables sont déjà utilisés dans diverses industries à des fins bactéricides de part leur forte concentration en chlorure de benzéthonium ajouté (10 à 20 %). La présente invention garantie une teneur n'excédant pas 1 p.p.m. de chlorure de benzéthonium présent à l'état naturel dans le pépin de pamplemousse. Suite à cette première mise en évidence de famille de molécule, nous avons montré les propriétés suivantes:  Similar products are already used in various industries for bactericidal purposes due to their high concentration of added benzethonium chloride (10 to 20%). The present invention guarantees a content not exceeding 1 p.p.m. of benzethonium chloride present in the natural state in grapefruit seed. Following this first demonstration of the family of molecules, we have shown the following properties:

Activité amincissante: par la mise en évidence de l'activité anti-  Slimming activity: by highlighting the anti-

phosphodiestérase de l'extrait de pépin de pamplemousse. Les résultats de ce test montrent une activité de l'extrait de pépin de pamplemousse analogue à l'activité de la caféine dont les propriétés qui ne sont plus à démontrer sont largement exploitées à ce jour dans ce domaine, aussi bien par voie orale que  phosphodiesterase from grapefruit seed extract. The results of this test show an activity of the grapefruit seed extract analogous to the activity of caffeine, the properties of which, which no longer need to be demonstrated, have been widely exploited to date in this field, both orally and

topique.topical.

Activité anti-inflammatoire: par la mise en évidence du pouvoir anti-  Anti-inflammatory activity: by demonstrating the anti-inflammatory power

inflammatoire selon le modèle d'induction par la carragénine utilisé pour les  inflammatory according to the carrageenan induction model used for

molécules pharmaceutiques. Ce test très sélectif montre une activité anti-  pharmaceutical molecules. This very selective test shows an anti-

inflammatoire de l'extrait de pépin de pamplemousse dès la première heure par  inflammatory grapefruit seed extract from the first hour by

diminution du volume de l'oedème podal.  decrease in the volume of podal edema.

Activité anti-oxydante: par la mise en évidence du pouvoir anti-oxydant vis  Antioxidant activity: by demonstrating the antioxidant power of screws

à vis des radicaux libres générés par un système xanthine/xanthine oxydase.  against free radicals generated by a xanthine / xanthine oxidase system.

D'après ces résultats, les activités de l'extrait de pépin de pamplemousse peuvent trouver de nombreuses applications en: - Soin corporel humain et/ou animal: amincissant, anti-inflammatoire, anti-radicaux libres, anti-acnée, anti-seborrhée, anti-comédons, anti- rougeurs. - Alimentation humaine et/ou animale: de part sa composition chimique et son apport nutritionnel potentiel de substances  According to these results, the activities of the grapefruit seed extract can find many applications in: - Human and / or animal body care: slimming, anti-inflammatory, anti-free radicals, anti-acne, anti-seborrhea , anti-blackheads, anti-redness. - Human and / or animal food: due to its chemical composition and its potential nutritional intake of substances

actives.active.

- Agricole: bactéricide et/ou enrichissant de part sa propre composition. Pour les applications topiques, I'extrait de pépin de pamplemousse peut être utilisé pur ou associé aux excipients classiquement utilisés tel que les celluloses et leurs dérivés, gommes, agents gélifiants, agents viscosants, agents emmulsionnants, agents de consistance, solvants, tensio-actifs. Ceci afin d'obtenir un produit fini en solution, en suspension, en gel, en émulsion ou microémulsion, en pâte. Il est également possible de préparer un produit fini ou semi-fini dans des  - Agricultural: bactericidal and / or enriching by its own composition. For topical applications, the grapefruit seed extract can be used pure or combined with conventionally used excipients such as celluloses and their derivatives, gums, gelling agents, viscosifying agents, emulsifying agents, consistency agents, solvents, surfactants . This is to obtain a finished product in solution, suspension, gel, emulsion or microemulsion, paste. It is also possible to prepare a finished or semi-finished product in

vecteurs de type liposomes, glycosphères, chylomicrons, macro- micro- et nano-  vectors such as liposomes, glycospheres, chylomicrons, macro- micro- and nano-

particules, macro- micro- et nano-capsules. Il est également possible de l'absorber sur des polymères organiques poudreux, talcs, bentonites et autres supports minéraux. Pour les applications orales, I'extrait de pépin de pamplemousse peut être utilisé pur ou introduit dans tout type de support destiné à l'alimentation humaine ou animale sous forme liquide, gélifiée, pâteuse ou solide. Le produit peut également être encapsulé sous forme sèche seul ou associé, ou encapsulé dans un milieu liquide aqueux ou huileux dans un enrobage tel que la gélatine ou autres  particles, macro- micro- and nano-capsules. It is also possible to absorb it on powdery organic polymers, talcs, bentonites and other mineral supports. For oral applications, the grapefruit seed extract can be used pure or introduced into any type of support intended for human or animal consumption in liquid, gelled, pasty or solid form. The product can also be encapsulated in dry form alone or in combination, or encapsulated in an aqueous or oily liquid medium in a coating such as gelatin or the like.

matières premières à usage semblable.  raw materials for similar use.

L'extrait de pépin de pamplemousse de la présente invention a montré selon les tests en vigueur de l'OCDE qu'il est très bien toléré par l'homme et  The grapefruit seed extract of the present invention has shown, according to current OECD tests, that it is very well tolerated by humans and

l'animal, il ne présente pas de toxicité orale ou d'effet irritant oculaire ou cutané.  the animal, it does not present any oral toxicity or any eye or skin irritant effect.

Claims (4)

REVENDICATIONS 1 - Compositions cosmétiques, dermopharmaceutiques, alimentaires ou  1 - Cosmetic, dermopharmaceutical, food or agricoles destinées à l'activité nutritionnelle, amincissante, antiinflammatoire, anti-  agricultural intended for nutritional activity, slimming, anti-inflammatory, anti oxydante, anti-acnée, anti-comédon, anti-séborrhée, anti-rougeurs, caractérisées en ce quelles comprennent un extrait de pépin de pamplemousse. 2 - Compositions cosmétiques, dermopharmaceutiques, alimentaires ou agricoles selon la revendication 1 caractérisées en ce que les extraits de  oxidizing, anti-acne, anti-comedo, anti-seborrhea, anti-redness, characterized in that they include a grapefruit seed extract. 2 - Cosmetic, dermopharmaceutical, food or agricultural compositions according to claim 1, characterized in that the extracts of pamplemousse précités sont obtenus à partir des pépins du fruit.  aforementioned grapefruit are obtained from the seeds of the fruit. 3 - Compositions cosmétiques, dermopharmaceutiques, alimentaires ou  3 - Cosmetic, dermopharmaceutical, food or io agricoles selon l'une quelconque des revendications de 1 à 2 caractérisées en ce  io agricultural according to any one of claims 1 to 2 characterized in that que l'extrait de pépin de pamplemousse est obtenu grâce à un ou plusieurs types  that the grapefruit seed extract is obtained through one or more types d'extractions appropriés au solvant sélectionné.  appropriate extracts for the selected solvent. 4 - Compositions cosmétiques, dermopharmaceutiques, alimentaires ou agricoles selon la revendication 3 caractérisées en ce que le solvant d'extraction i5 soit choisi parmi le groupe constitué de: glycérine, eau, glycol, alcool,  4 - Cosmetic, dermopharmaceutical, food or agricultural compositions according to claim 3, characterized in that the extraction solvent i5 is chosen from the group consisting of: glycerin, water, glycol, alcohol, eau/glycérine, eau/glycol, eau/alcool.  water / glycerin, water / glycol, water / alcohol. - Compositions cosmétiques, dermopharmaceutiques, alimentaires ou  - Cosmetic, dermopharmaceutical, food or agricoles selon l'une quelconque des revendications de I à 4 caractérisées en ce  agricultural according to any one of claims 1 to 4, characterized in that que l'extrait final est utilisé soit sous forme liquide, soit sous forme pateuse, soit  that the final extract is used either in liquid form, or in pasty form, or sous forme sèche.in dry form. 6 - Compositions cosmétiques, dermopharmaceutiques, alimentaires ou  6 - Cosmetic, dermopharmaceutical, food or agricoles selon l'une quelconque des revendications de 1 à 5 caractérisées en ce  agricultural according to any one of claims 1 to 5 characterized in that que l'extrait de pépin de pamplemousse soit utilisé tel quel ou, incorporé dans des vecteurs de pénétration cutanée ou d'absorption orale de type capsules, gélules,  that the grapefruit seed extract be used as it is or, incorporated into skin penetration or oral absorption vectors of the capsule, capsule type, liposomes, glycosphères, chylomicrons, macro- micro- et nanoparticules, macro-  liposomes, glycospheres, chylomicrons, macro- micro- and nanoparticles, macro- micro et nanocapsules ou, absorbé sur des polymères organiques poudreux, talcs,  micro and nanocapsules or, absorbed on powdery organic polymers, talcs, bentonites et autres supports minéraux.  bentonites and other mineral supports.
FR9904765A 1999-04-12 1999-04-12 COSMETIC, DERMOPHARMACEUTICAL, FOOD OR AGRICULTURAL COMPOSITIONS WITH NUTRITIONAL ACTIVITY, SLIMMING, ANTI-INFLAMMATORY, ANTI-OXIDANT, ANTI-ACNE, CONTAINING A GRAPEFRUIT EXTRACT Expired - Fee Related FR2791893B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9904765A FR2791893B1 (en) 1999-04-12 1999-04-12 COSMETIC, DERMOPHARMACEUTICAL, FOOD OR AGRICULTURAL COMPOSITIONS WITH NUTRITIONAL ACTIVITY, SLIMMING, ANTI-INFLAMMATORY, ANTI-OXIDANT, ANTI-ACNE, CONTAINING A GRAPEFRUIT EXTRACT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9904765A FR2791893B1 (en) 1999-04-12 1999-04-12 COSMETIC, DERMOPHARMACEUTICAL, FOOD OR AGRICULTURAL COMPOSITIONS WITH NUTRITIONAL ACTIVITY, SLIMMING, ANTI-INFLAMMATORY, ANTI-OXIDANT, ANTI-ACNE, CONTAINING A GRAPEFRUIT EXTRACT

Publications (2)

Publication Number Publication Date
FR2791893A1 true FR2791893A1 (en) 2000-10-13
FR2791893B1 FR2791893B1 (en) 2001-05-25

Family

ID=9544468

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9904765A Expired - Fee Related FR2791893B1 (en) 1999-04-12 1999-04-12 COSMETIC, DERMOPHARMACEUTICAL, FOOD OR AGRICULTURAL COMPOSITIONS WITH NUTRITIONAL ACTIVITY, SLIMMING, ANTI-INFLAMMATORY, ANTI-OXIDANT, ANTI-ACNE, CONTAINING A GRAPEFRUIT EXTRACT

Country Status (1)

Country Link
FR (1) FR2791893B1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005025527A1 (en) 2003-09-09 2005-03-24 Dsm Ip Assets B.V. Orally effective, essentially water-free topical agent containing one or several oxidation-sensitive substances
WO2009021488A1 (en) * 2007-08-10 2009-02-19 Zsolt Csabai Antioxidantcomplex based on grape vital (based on citrus seed and/or grape seed and/or flavonoid)
CN103860438A (en) * 2014-03-31 2014-06-18 湖北亦禾生态农业有限公司 Whitening scrub cream prepared from shaddock peel
FR3096893A1 (en) * 2019-06-06 2020-12-11 Laboratoire Exact COMPOSITION BASED ON YOUNG SHOOTS EXTRACT AND USE FOR THE PREVENTION AND TREATMENT OF DISEASES RELATED TO AGING

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128139A (en) * 1991-02-15 1992-07-07 Nu Skin International, Inc. Composition containing liposome-entrapped grapefruit seed extract and method for making

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128139A (en) * 1991-02-15 1992-07-07 Nu Skin International, Inc. Composition containing liposome-entrapped grapefruit seed extract and method for making

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005025527A1 (en) 2003-09-09 2005-03-24 Dsm Ip Assets B.V. Orally effective, essentially water-free topical agent containing one or several oxidation-sensitive substances
WO2009021488A1 (en) * 2007-08-10 2009-02-19 Zsolt Csabai Antioxidantcomplex based on grape vital (based on citrus seed and/or grape seed and/or flavonoid)
CN103860438A (en) * 2014-03-31 2014-06-18 湖北亦禾生态农业有限公司 Whitening scrub cream prepared from shaddock peel
CN103860438B (en) * 2014-03-31 2016-04-13 湖北亦禾生态农业有限公司 The whitening scrubbing cream that a kind of pomelo peel is made
FR3096893A1 (en) * 2019-06-06 2020-12-11 Laboratoire Exact COMPOSITION BASED ON YOUNG SHOOTS EXTRACT AND USE FOR THE PREVENTION AND TREATMENT OF DISEASES RELATED TO AGING

Also Published As

Publication number Publication date
FR2791893B1 (en) 2001-05-25

Similar Documents

Publication Publication Date Title
CA1178209A (en) Slenderizing and anti-cellulite cosmetic composition of vegetable extract containing saponines, arnica montana extract, and cola bean extract and method of use
JP2009509917A (en) Use of Sporopolenin
CA3164351A1 (en) Method for obtaining an aqueous extract of lavender, compositions comprising such an extract and their cosmetic uses
JPH09157176A (en) Antiallergic agent containing extract of hypericum erectum thunb. and tilia miqueliana maxim.
EP0512040A1 (en) Cosmetic compositions containing an essence of sunflower oil cake (helianthus annuus).
JP4104180B2 (en) Lipase activity promoter
EP0977550B1 (en) Use of at least one irvingia gabonensis extract in a cosmetic and/or pharmaceutical product
EP1530480B1 (en) Cosmetic composition comprising monosaccharides or polysaccharides, uses and treatment methods
FR2791893A1 (en) Use of grapefruit seed extract obtained by washing and grinding the seeds and extracting them with a solvent, in cosmetic, dermatological, food and agricultural compositions
FR2770228A1 (en) Proanthocyanidine oligomer concentrates obtained by fermenting Schinopsis lorenzii extract
FR2662078A1 (en) Cosmetological composition based on a mixture of powdered clay and powdered plants
WO2020156981A1 (en) Method for obtaining an extract of patchouli leaves and cosmetic uses thereof
EP2931232B1 (en) Cosmetic use of the combination of a carob germ extract and caffeine as a slimming active agent
FR2880278A1 (en) Use of oil or proteins extracted from Plukenetia volubilis seed as an active ingredient in the preparation of cosmetic composition or dermatological product e.g. as skin and hair care product
FR2659014A1 (en) Hair lotion intended for halting hair loss and as a hair restorer, composed of vegetable, mineral and animal components in the form of homeopathic dilutions
JP2002284632A (en) Extinction substance for superoxide anion extracted from sake lees as effective component
FR2590169A1 (en) Cosmetic composition containing biostimulins
EP2931231A2 (en) Cosmetic use of a carob seed extract as a slimming active agent
WO2000030604A1 (en) Composition for preventing and treating cellulitis
FR2729079A1 (en) Cosmetic compsn contg synthetic ceramide and protease
JP2001206822A (en) Cosmetic for hair
WO2000067767A1 (en) Poplar bud extract and its combination with squalane as anti-inflammatory medicine
KR101883543B1 (en) An allergy-inhibiting sea grape extract, its preparation method and application thereof
FR2805158A1 (en) COSMETIC OR MEDICINAL COMPOSITION CONTAINING A SESQUITERPENIC LACTONE OR THE LIKE FOR TREATING DISORDERS RELATED TO PILAR GROWTH, AND PROCESS FOR PREPARING THE SAME.
FR2657255A1 (en) Description of novel cosmetic preparations in which the active principles are trapped in a polymer network grafted at the surface of silica particles

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20051230