FR2755858A1 - Compositions for treating skin irritation in babies - Google Patents
Compositions for treating skin irritation in babies Download PDFInfo
- Publication number
- FR2755858A1 FR2755858A1 FR9614136A FR9614136A FR2755858A1 FR 2755858 A1 FR2755858 A1 FR 2755858A1 FR 9614136 A FR9614136 A FR 9614136A FR 9614136 A FR9614136 A FR 9614136A FR 2755858 A1 FR2755858 A1 FR 2755858A1
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- FR
- France
- Prior art keywords
- compositions
- dermocosmetic
- approx
- contain
- essence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
La présente invention concerne des compositions dermopharmaceutiques à base de produits
d'origine végétale, animale et d'essence de plantes, l'essence de plantes favorisant la cicatrisation
et l'anti-inflammation, destinées à soigner les irritations provoquées par la macération des selles
et de l'urine dans les couches des nouveau-nés.The present invention relates to dermopharmaceutical compositions based on products
of plant, animal and plant essence, the essence of plants promoting healing
and anti-inflammation, intended to treat irritations caused by maceration of stools
and urine in the diapers of newborns.
La peau du nouveau-né ressemble beaucoup par sa structure à la peau de l'adulte, si l'enfant est à terme, les prématurés ayant une couche cornée n'assurant pas encore totalement sa fonction de barrière. Normalement le pH de la peau est acide, de 4 à 5,5. La peau est capable de contrer et de
subir les agressions extérieures chez l'enfant comme chez l'adulte.The structure of a newborn baby's skin is very similar to that of an adult's skin, if the child is long term, premature babies with a stratum corneum do not yet fully fulfill its barrier function. Normally the pH of the skin is acidic, from 4 to 5.5. The skin is able to counter and
undergo external aggressions in children as in adults.
Mais chez les nouveau-nés, les couches peuvent créer un environnement plus dur que celui habituellement rencontré par la peau, provoquant un risque de dermatite : le derme est agressé, la peau est irritée, enflammée.But in newborns, the diapers can create a harsher environment than that usually encountered by the skin, causing a risk of dermatitis: the dermis is attacked, the skin is irritated, inflamed.
Le principal effecteur dans l'irritation qui caractérise la dermatite des couches ou érythème fessier est le mélange urines-selles.The main effector in the irritation that characterizes diaper dermatitis or diaper rash is the urine-stool mixture.
En effet, l'urée contenue dans l'urine est dégradée en amnoniaque par les uréases ce qui induit une augmentation de pH. Lorsque le pH devient basique, les enzymes fabriquées lors de la
digestion telles que les protéases et les lipases d'origine pancréatique ou intestinale, voient leur
activité donc leur pouvoir irritant augmenter, les lipases attaquant en particulier les triglycérides
du sébum et provoquant la libération d'acides gras.In fact, the urea contained in the urine is degraded to amnonia by urease which induces an increase in pH. When the pH becomes basic, the enzymes produced during the
digests such as proteases and lipases of pancreatic or intestinal origin, see their
activity therefore their irritant capacity increase, the lipases attacking in particular the triglycerides
sebum and causing the release of fatty acids.
La couche cornée rendue perméable par une hyperhydratation, un frottement important, une digestion par les enzymes, perd sa fonction de barrière et laisse passer d'autres molécules irritantes telles que les sels biliaires.The stratum corneum made permeable by hyperhydration, significant friction, digestion by enzymes, loses its barrier function and lets through other irritant molecules such as bile salts.
On a pu observer dans certains cas une véritable digestion de l'épiderme du siège de l'enfant due à l'action d'uréases, de lipases et de protéases.In some cases, a real digestion of the epidermis of the child's seat has been observed due to the action of ureases, lipases and proteases.
Pour lutter contre l'érythème fessier, les moyens de la thérapie actuelle, tels que la surveillance du régime alimentaire de l'enfant et du type de lange utilisé, l'assurance d'une bonne hygiène, l'application de crèmes classiques, ne sont pas jugés satisfaisants par un grand nombre de dermatologues et de pédiatres.To combat diaper rash, the means of current therapy, such as monitoring the child's diet and the type of diaper used, ensuring good hygiene, applying conventional creams, do not are not considered satisfactory by a large number of dermatologists and pediatricians.
Or, et c'est l'objet de la présente invention, l'association de produits d'origine végétale, animale et d'essence de plantes, permet de soigner les irritations provoquées par les selles et de diminuer considérablement les actions lipolytiques, protéolytiques et uréasiques, causes de l'irritation.However, and this is the object of the present invention, the combination of products of plant, animal and plant essence, makes it possible to treat the irritations caused by the stools and to considerably reduce the lipolytic, proteolytic actions. and ureasic, causes of irritation.
L'invention a pour objet de nouvelles compositions pharmaceutiques caractérisées en ce qu'elles renferment de l'essence de plantes et plusieurs produits d'origine végétale et animale.The invention relates to new pharmaceutical compositions characterized in that they contain the essence of plants and several products of plant and animal origin.
L'invention a particulièrement pour objet de nouvelles compositions pharmaceutiques telles que définies ci-dessus caractérisées en ce que les produits d'origine végétale qu'elles renferment sont de la fleur d'amidon et de l'huile d'olive.The invention particularly relates to new pharmaceutical compositions as defined above, characterized in that the products of plant origin which they contain are starch flower and olive oil.
L'invention a particulièrement pour objet de nouvelles compositions pharmaceutiques telles que définies ci-dessus caractérisées en ce que les produits d'origine animale qu'elles renferment sont de la cire vierge et de la panne de porc. The invention particularly relates to new pharmaceutical compositions as defined above, characterized in that the products of animal origin which they contain are virgin wax and pork purée.
L'invention a particulièrement pour objet de nouvelles compositions pharmaceutiques telles que définies ci-dessus caractérisées en ce qu'elles renferment entre environ 1 grs et environ 5 grs d'essence de lavande et/ou de marjolaine.The invention particularly relates to new pharmaceutical compositions as defined above, characterized in that they contain between approximately 1 grs and approximately 5 grs of lavender and / or marjoram essence.
L'invention a particulièrement pour objet de nouvelles compositions pharmaceutiques telles que définies ci-dessus caractérisées en ce qu'elles renferment:
pour env. 276 à 280 grs - de la cire vierge, 65 grs env.The invention particularly relates to new pharmaceutical compositions as defined above, characterized in that they contain:
for approx. 276 to 280 grs - virgin wax, 65 grs approx.
- de l'huile d'olive, 125 grs env.- olive oil, 125 grs approx.
- de la panne de porc, 75 grs env.- of the pork purlin, 75 grs approx.
- de la fleur d'amidon, 10 grs env.- starch flower, 10 grs approx.
- de l'essence de plantes (plus particulièrement lavande ou marjolaine) de 1 grs à 5 grs
L'exemple précité illustre l'invention sans toutefois la limiter.- essence of plants (more particularly lavender or marjoram) from 1 gr to 5 gr
The above example illustrates the invention without however limiting it.
Ces compositions sont destinées spécialement au soin des érythèmes fessiers chez le nouveau-né et ont une double action curative et préventive.These compositions are specially intended for the care of diaper rashes in newborns and have a double curative and preventive action.
Les compositions pharmaceutiques selon l'invention peuvent se présenter sous toutes les formes utilisées en dermatologie, plus particulièrement de manière à pouvoir être administrées par voie locale : crèmes, pommades ou gel conditionnés, selon le cas, en pots ou en tubes, en flacon de verre ou de plastique et éventuellement en flacon doseur.The pharmaceutical compositions according to the invention can be in all the forms used in dermatology, more particularly so that they can be administered locally: creams, ointments or gel packaged, as the case may be, in jars or tubes, in vial of glass or plastic and possibly in a dosing bottle.
Les formes pharmaceutiques sont préparées selon les méthodes usuelles.The pharmaceutical forms are prepared according to the usual methods.
Pour chaque forme, on peut éventuellement avoir recours à des excipients appropriés. Ces excipients doivent avoir toutes les qualités habituellement requises. Dans le cas d'une administration locale, ils doivent être doués d'une grande affinité pour la peau, être parfaitement bien tolérés, stables, présenter une consistance adéquate permettant une utilisation facile et agréable. A titre d'exemple, l'ont peut citer des stabilisants, des émulsionnants, des conservateurs, des parfums, des colorants ou d'autres excipients connus et couramment utilisés.For each form, it is possible to have recourse to appropriate excipients. These excipients must have all the qualities usually required. In the case of local administration, they must have a great affinity for the skin, be perfectly well tolerated, stable, have an adequate consistency allowing easy and pleasant use. By way of example, mention may be made of stabilizers, emulsifiers, preservatives, perfumes, dyes or other known and commonly used excipients.
Les formes préférées sont les compositions pharmaceutiques telles que définies ci-dessus caractérisées en ce qu'elles se présentent sous forme de gel ou de crème.The preferred forms are the pharmaceutical compositions as defined above, characterized in that they are in the form of a gel or a cream.
L'invention a également pour objet de nouvelles compositions cosmétiques destinées notamment au soin des érythèmes fessiers chez le nouveau-né caractérisées en ce qu'elles renferment de l'essence de plantes et plusieurs produits d'origine végétale et animale.The invention also relates to new cosmetic compositions intended in particular for the care of diaper rash in newborns, characterized in that they contain the essence of plants and several products of plant and animal origin.
Les compositions cosmétiques peuvent être préparées en utilisant les mêmes ingrédients que les compositions pharmaceutiques. Les doses peuvent être adaptées si nécessaire.The cosmetic compositions can be prepared using the same ingredients as the pharmaceutical compositions. The doses can be adjusted if necessary.
L'invention concerne ainsi notamment l'application à titre de produit cosmétique des compositions telles que définies ci-dessus.The invention thus relates in particular to the application as a cosmetic product of the compositions as defined above.
L'invention concerne tout particulièrement une méthode de traitement cosmétique des érythèmes fessiers chez le nouveau-né caractérisée en ce que l'on utilise les compositions cosmétiques telles que définies ci-dessus. The invention relates very particularly to a method of cosmetic treatment of diaper rash in newborns, characterized in that the cosmetic compositions as defined above are used.
L'invention a également pour objet de nouvelles compositions dermocosmétiques destinées notamment au soin des érythèmes fessiers chez le nouveau-né caractérisées en ce qu'elles renferment de l'essence de plantes et plusieurs produits d'origine végétale et animale.The invention also relates to new dermocosmetic compositions intended in particular for the care of diaper rash in newborns, characterized in that they contain the essence of plants and several products of plant and animal origin.
Les compositions dermocosmétiques peuvent être préparées en utilisant les mêmes ingrédients que les compositions pharmaceutiques ou cosmétiques. Les doses peuvent être adaptées si nécessaire.The dermocosmetic compositions can be prepared using the same ingredients as the pharmaceutical or cosmetic compositions. The doses can be adjusted if necessary.
L'invention concerne ainsi notamment l'application à titre de produit dermocosmétiques des compositions telles que définies ci-dessus.The invention thus relates in particular to the application as dermocosmetic product of the compositions as defined above.
L'invention concerne tout particulièrement une méthode de traitement dermocosmétiques des érythèmes fessiers chez le nouveau-né caractérisée en ce que l'on utilise les compositions dermocosmétiques telles que définies ci-dessus.The invention relates very particularly to a dermocosmetic treatment method for diaper rash in newborns, characterized in that the dermocosmetic compositions as defined above are used.
Les différentes formes pharmaceutiques, cosmétiques et dermocosmétiques mentionnées cidessus peuvent être obtenues selon les méthodes usuelles utilisées dans ces domaines.The various pharmaceutical, cosmetic and dermocosmetic forms mentioned above can be obtained according to the usual methods used in these fields.
L'invention a particulièrement pour objet de nouvelles compositions dermocosmétiques telles que définies ci-dessus caractérisées en ce qu'elles renferment: - de la cire vierge, entre 13 et 33 % env.The invention particularly relates to new dermocosmetic compositions as defined above, characterized in that they contain: - virgin wax, between 13 and 33% approx.
- de l'huile d'olive, entre 34 et 54 % env.- olive oil, between 34 and 54% approx.
- de la panne de porc, entre 16 et 36 % env.- pork purlins, between 16 and 36% approx.
- de la fleur d'amidon, entre 1 et 10 % env.- of the starch flower, between 1 and 10% approx.
- de l'essence de lavande et/ou de marjolaine entre 0,30 et 10 % env.- lavender and / or marjoram essence between 0.30 and 10% approx.
On entend bien évidemment par panne de porc, uniquement la graisse.Obviously, by pork breakdown, we mean only fat.
L'exemple précité illustre l'invention sans toutefois la limiter.The above example illustrates the invention without however limiting it.
L'invention a particulièrement pour objet de nouvelles compositions dermocosmétiques telles que définies ci-dessus caractérisées en ce qu'elles renferment entre environ 1 % et environ 5 % en poids d'essence de lavande et/ou de marjolaine.The invention particularly relates to new dermocosmetic compositions as defined above, characterized in that they contain between approximately 1% and approximately 5% by weight of lavender and / or marjoram essence.
Ces compositions sont destinées spécialement au soin des érythèmes fessiers chez le nouveau-né et ont une double action curative et préventive. These compositions are specially intended for the care of diaper rashes in newborns and have a double curative and preventive action.
Claims (10)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9614136A FR2755858A1 (en) | 1996-11-20 | 1996-11-20 | Compositions for treating skin irritation in babies |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9614136A FR2755858A1 (en) | 1996-11-20 | 1996-11-20 | Compositions for treating skin irritation in babies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2755858A1 true FR2755858A1 (en) | 1998-05-22 |
Family
ID=9497804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9614136A Withdrawn FR2755858A1 (en) | 1996-11-20 | 1996-11-20 | Compositions for treating skin irritation in babies |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2755858A1 (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2364437A1 (en) * | 1973-12-24 | 1975-06-26 | Henkel & Cie Gmbh | Anti-inflammatory benzoxazol-2-carbamidines - used in cosmetics e.g. anti-sunburn compsns., shaving creams, baby powder, etc. |
| US4209506A (en) * | 1977-07-28 | 1980-06-24 | L'oreal | Aluminum tris-(N-oxypyridine-2-thiolate); cosmetic or pharmaceutical compositions containing the same and the use of said compositions |
| FR2498451A1 (en) * | 1981-01-26 | 1982-07-30 | Delory Bertrand | Topical compsns. for body care and treatment - contg. clay, physiological agent, and vegetable prod. |
| FR2587208A1 (en) * | 1985-09-19 | 1987-03-20 | Scherninski Francois | Lotion for combatting hair loss and promoting hair regeneration |
| EP0348091A1 (en) * | 1988-06-20 | 1989-12-27 | Shiseido Company Limited | Aerosol composition |
| DE4320523C1 (en) * | 1993-06-21 | 1994-07-14 | Michael Frey | Compsns. for treating summer mange, esp. in horses |
| WO1995026183A1 (en) * | 1994-03-29 | 1995-10-05 | Helsinki University Licensing Ltd Oy | Cosmetic and pharmaceutical composition containing wheat shoot extract |
| EP0699710A2 (en) * | 1994-09-01 | 1996-03-06 | Bridgestone Corporation | Polymeric reticulated structure and method for making |
-
1996
- 1996-11-20 FR FR9614136A patent/FR2755858A1/en not_active Withdrawn
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2364437A1 (en) * | 1973-12-24 | 1975-06-26 | Henkel & Cie Gmbh | Anti-inflammatory benzoxazol-2-carbamidines - used in cosmetics e.g. anti-sunburn compsns., shaving creams, baby powder, etc. |
| US4209506A (en) * | 1977-07-28 | 1980-06-24 | L'oreal | Aluminum tris-(N-oxypyridine-2-thiolate); cosmetic or pharmaceutical compositions containing the same and the use of said compositions |
| US4209506B1 (en) * | 1977-07-28 | 1991-05-21 | Oreal | |
| FR2498451A1 (en) * | 1981-01-26 | 1982-07-30 | Delory Bertrand | Topical compsns. for body care and treatment - contg. clay, physiological agent, and vegetable prod. |
| FR2587208A1 (en) * | 1985-09-19 | 1987-03-20 | Scherninski Francois | Lotion for combatting hair loss and promoting hair regeneration |
| EP0348091A1 (en) * | 1988-06-20 | 1989-12-27 | Shiseido Company Limited | Aerosol composition |
| DE4320523C1 (en) * | 1993-06-21 | 1994-07-14 | Michael Frey | Compsns. for treating summer mange, esp. in horses |
| WO1995026183A1 (en) * | 1994-03-29 | 1995-10-05 | Helsinki University Licensing Ltd Oy | Cosmetic and pharmaceutical composition containing wheat shoot extract |
| EP0699710A2 (en) * | 1994-09-01 | 1996-03-06 | Bridgestone Corporation | Polymeric reticulated structure and method for making |
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| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |