FR2752731A1 - Antiseptic compositions for use in dentistry - Google Patents
Antiseptic compositions for use in dentistry Download PDFInfo
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- FR2752731A1 FR2752731A1 FR9610672A FR9610672A FR2752731A1 FR 2752731 A1 FR2752731 A1 FR 2752731A1 FR 9610672 A FR9610672 A FR 9610672A FR 9610672 A FR9610672 A FR 9610672A FR 2752731 A1 FR2752731 A1 FR 2752731A1
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- dental
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- 239000000203 mixture Substances 0.000 title claims abstract description 19
- 230000002421 anti-septic effect Effects 0.000 title description 2
- OCBHHZMJRVXXQK-UHFFFAOYSA-M benzyl-dimethyl-tetradecylazanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 OCBHHZMJRVXXQK-UHFFFAOYSA-M 0.000 claims abstract description 9
- 229940094510 myristalkonium chloride Drugs 0.000 claims abstract description 9
- PHOQVHQSTUBQQK-SQOUGZDYSA-N D-glucono-1,5-lactone Chemical compound OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O PHOQVHQSTUBQQK-SQOUGZDYSA-N 0.000 claims abstract description 8
- RARSHUDCJQSEFJ-UHFFFAOYSA-N p-Hydroxypropiophenone Chemical compound CCC(=O)C1=CC=C(O)C=C1 RARSHUDCJQSEFJ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 235000012209 glucono delta-lactone Nutrition 0.000 claims abstract description 7
- 239000000182 glucono-delta-lactone Substances 0.000 claims abstract description 7
- 229960003681 gluconolactone Drugs 0.000 claims abstract description 7
- 238000001356 surgical procedure Methods 0.000 claims abstract description 5
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims abstract description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229920000642 polymer Polymers 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 239000000243 solution Substances 0.000 claims description 9
- 239000012530 fluid Substances 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 3
- 239000002324 mouth wash Substances 0.000 claims description 3
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 abstract description 4
- 239000007788 liquid Substances 0.000 abstract description 3
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 abstract description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract description 2
- 229960000458 allantoin Drugs 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract description 2
- 239000000796 flavoring agent Substances 0.000 abstract description 2
- 239000013003 healing agent Substances 0.000 abstract description 2
- 239000000600 sorbitol Substances 0.000 abstract description 2
- 208000007117 Oral Ulcer Diseases 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 230000009471 action Effects 0.000 description 3
- 238000005202 decontamination Methods 0.000 description 3
- 230000003588 decontaminative effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000003389 potentiating effect Effects 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 208000006558 Dental Calculus Diseases 0.000 description 2
- 229920002125 Sokalan® Polymers 0.000 description 2
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 239000002978 dental impression material Substances 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 206010001889 Alveolitis Diseases 0.000 description 1
- 241000723347 Cinnamomum Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 235000006679 Mentha X verticillata Nutrition 0.000 description 1
- 235000002899 Mentha suaveolens Nutrition 0.000 description 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002353 algacidal effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- 229910001422 barium ion Inorganic materials 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 235000017803 cinnamon Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 201000001155 extrinsic allergic alveolitis Diseases 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 208000022098 hypersensitivity pneumonitis Diseases 0.000 description 1
- 230000004941 influx Effects 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 208000003265 stomatitis Diseases 0.000 description 1
- 229910001427 strontium ion Inorganic materials 0.000 description 1
- UBXAKNTVXQMEAG-UHFFFAOYSA-L strontium sulfate Chemical class [Sr+2].[O-]S([O-])(=O)=O UBXAKNTVXQMEAG-UHFFFAOYSA-L 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000003253 viricidal effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
Abstract
Description
COMPOSITION UTILE NOTAMMENT EN CHIRURGIE DENTAIRE
La présente invention intéresse le domaine de la santé et vise plus particulièrement les produits ou substances utilisés pour décontaminer ou simplement nettoyer les appareils et instruments médicaux et chirurgicaux.COMPOSITION USEFUL IN PARTICULAR IN DENTAL SURGERY
The present invention is of interest in the health field and relates more particularly to the products or substances used for decontaminating or simply cleaning medical and surgical apparatus and instruments.
Elle concerne plus précisément, mais de manière non exclusive, les produits employés pour les soins buccaux et ceux utilises pour le traitement décontaminant des installations et matériels de chirurgie dentaire.It relates more precisely, but not exclusively, to the products used for oral care and those used for the decontaminating treatment of dental surgery facilities and equipment.
Les praticiens savent que la bouche est l'un des principaux foyers du corps humain où est observée une forte proliferation bactérienne. L'emploi necessaire, lors des interventions, de fluides divers, notamment d'eau chaude, offre par ailleurs un excellent moyen de transport aux agents de contamination qui peuvent ainsi coloniser les diverses parties actives des appareils de soins de même que les conduites qui servent à leur alimentation. Practitioners know that the mouth is one of the main foci of the human body where a strong bacterial proliferation is observed. The necessary use, during interventions, of various fluids, in particular hot water, moreover offers an excellent means of transport to the agents of contamination which can thus colonize the various active parts of the care devices as well as the pipes which serve to their diet.
On connaît depuis longtemps certaines substances antiseptiques utilisées notamment en chirurgie dentaire. Si leur action de décontamination est satisfaisante, on observe toutefois qu'elle est limitée au seul traitement de l'eau employée dans les unites de travail. Par exemple, le FR-A-2.677.013 décrit un dispositif raccordé entre l'arrivée d'eau et l'unité principale de soins permettant l'introduction dans l'eau d'une solution ayant des propriétés désinfectantes et détartrantes. Certain antiseptic substances used in particular in dental surgery have been known for a long time. If their decontamination action is satisfactory, it is however observed that it is limited to the sole treatment of the water used in the work units. For example, FR-A-2,677,013 describes a device connected between the water supply and the main care unit allowing the introduction into the water of a solution having disinfecting and descaling properties.
Ce faisant, il a été négligé un des aspects importants du travail du praticien qui est constitué par l'élaboration d'empreintes dentaires. On sait à cet égard que les matériaux employes pour les empreintes dentaires sont particulièrement délicats à utiliser. Une trop importante sécrétion de salive, par exemple, au moment de la prise d'empreinte peut affecter la qualite de cette dernière. In doing so, one of the important aspects of the practitioner's work, which consists of the preparation of dental impressions, has been overlooked. It is known in this regard that the materials used for dental impressions are particularly delicate to use. Too much saliva secretion, for example, at the time of the impression can affect the quality of the latter.
Le besoin s'est ainsi fait sentir de disposer d'un produit qui possède un pouvoir de décontamination de l'eau alimentant les installations dentaires et qui permette egalement d'éviter la formation de tartre dans les conduites où s'effectue une telle circulation d'eau, tout en présentant une activité potentialisatrice des matériaux d'empreintes dentaires. The need was thus felt to have a product which has the power to decontaminate the water supplying dental facilities and which also makes it possible to avoid the formation of scale in the pipes where such circulation takes place. water, while presenting a potentiating activity of dental impression materials.
La composition selon l'invention permet d'atteindre cet objectif ainsi que d'autres qui apparaîtront à la lecture des développements qui suivent. The composition according to the invention achieves this objective as well as others which will appear on reading the developments which follow.
L'activité de décontamination de l'eau et l'activité de potentialisation des matériaux d'empreintes dentaires résultent principalement de l'association de deux principes actifs : le premier étant constitué par le digluconate de chlorhexidine, le second par le chlorure de myristalkonium. The water decontamination activity and the potentiation activity of dental impression materials mainly result from the combination of two active ingredients: the first being chlorhexidine digluconate, the second by myristalkonium chloride.
L'association du digluconate de chlorhexidine et du chlorure de myristalkonium présente en effet des propriétés bactéricides, virucides et fongicides correspondant aux normes actuellement en vigueur et qui peuvent en outre être utiles dans le traitement des aphtes, stomatites, gingivites, alveolites ou parodontites. De plus, le chlorure de myristalkonium est connu pour son activité algicide. The combination of chlorhexidine digluconate and myristalkonium chloride has indeed bactericidal, virucidal and fungicidal properties corresponding to the standards currently in force and which can also be useful in the treatment of canker sores, stomatitis, gingivitis, alveolitis or periodontitis. In addition, myristalkonium chloride is known for its algicidal activity.
On dispose ainsi d'un produit qui permet de décontaminer l'eau circulant dans les installations dentaires, qui évite l'apparition et la prolifération des algues dans les différentes parties de ces installations et qui peut intervenir dans le traitement de certaines affections de la cavité buccale. There is thus a product which makes it possible to decontaminate the water circulating in dental installations, which prevents the appearance and proliferation of algae in the various parts of these installations and which can intervene in the treatment of certain affections of the cavity buccal.
On notera par ailleurs que le chlorure de myristalkonium permet de potentialiser l'action du digluconate de chlorhexidine ce qui permet de diminuer les quantités de ce dernier. It will also be noted that myristalkonium chloride makes it possible to potentiate the action of chlorhexidine digluconate, which makes it possible to reduce the amounts of the latter.
I1 a en outre eté observé que ces composants jouaient un rôle de tensioactif favorisant les propriétés des matériaux utilisés pour le realisation d'empreintes dentaires, plus particulièrement des hydrocolloides irréversibles, ceci en provoquant une diminution de l'afflux salivaire. It has further been observed that these components play a role of surfactant promoting the properties of the materials used for making dental impressions, more particularly irreversible hydrocolloids, this causing a reduction in the salivary influx.
Ainsi, avec l'association du digluconate de chlorhexidine et du chlorure de myristalkonium, on dispose d'un produit qui tout en assurant notamment une décontamination des empreintes dentaires permet de potentialiser les propriétés des matériaux entrant dans leur composition. Thus, with the combination of chlorhexidine digluconate and myristalkonium chloride, a product is available which, while ensuring in particular decontamination of dental impressions, makes it possible to potentiate the properties of the materials used in their composition.
De préférence, la composition ci-dessus décrite est préparée sous forme liquide concentrée qui sera diluée au moment de son emploi, cette solution etant alors utilisée par exemple en bains de bouche ou pulvérisations. Bien entendu, une telle solution sera préparée avec l'adjonction d'excipients et de colorants habituellement utilisés en pharmacie. Preferably, the composition described above is prepared in concentrated liquid form which will be diluted at the time of its use, this solution then being used for example in mouthwashes or sprays. Of course, such a solution will be prepared with the addition of excipients and dyes usually used in pharmacy.
L'activité anti-tartre est obtenue par l'association de la glucono-deltalactone et d'un polymère de l'acide acrylique qui seront ajoutés à la préparation précédente. La glucono-delta-lactone présente en effet une action séquestrante des ions calcium, magnésium, baryum et strontium alors que le polymère de l'acide acrylique agit par un phénomène de seuil qui empêche la formation et la croissance des cristaux de tartre en déplaçant l'équilibre dans le sens de la redissolution. Le sulfates de calcium, de baryum et de strontium restent ainsi en solution au-delà de leur solubilité normale. The anti-tartar activity is obtained by the association of glucono-deltalactone and a polymer of acrylic acid which will be added to the previous preparation. Glucono-delta-lactone has a sequestering action of calcium, magnesium, barium and strontium ions while the acrylic acid polymer acts by a threshold phenomenon which prevents the formation and growth of tartar crystals by displacing the balance in the direction of redissolution. Calcium, barium and strontium sulfates thus remain in solution beyond their normal solubility.
On notera par ailleurs que la glucono-delta-lactone permet de stabiliser la solution et de masquer l'amertume de la chlorehexidine. It will also be noted that glucono-delta-lactone stabilizes the solution and masks the bitterness of chlorinehexidine.
De préférence, les composants entrant dans la préparation ci-dessus décrite seront employés selon les dosages donnés par la formule suivante:
Digluconate de chlorhexidine: 20 à 100 ml
Chlorure de myristalkonium: 3 à 10 g
Polymère de l'acide acrylique:10 à 50 ppm
Glucono-delta-lactone: 2 à 15 g auxquels seront ajoutés un agent cicatrisant des petites ulcérations de la muqueuse buccale, plus particulièrement l'allantoïne, dans une proportion de 1 à 5 g, un adjuvant d'isotonicite : le sorbitol sous forme liquide, dans une proportion de 20 à 70 ml, un arôme naturel, par exemple l'orange cannelle et un colorant, par exemple vert menthe, le tout dans de l'eau déminéralisée (qsp 1 litre).Preferably, the components entering into the preparation described above will be used according to the dosages given by the following formula:
Chlorhexidine digluconate: 20 to 100 ml
Myristalkonium chloride: 3 to 10 g
Acrylic acid polymer: 10 to 50 ppm
Glucono-delta-lactone: 2 to 15 g to which will be added a healing agent for small ulcers of the oral mucosa, more particularly allantoin, in a proportion of 1 to 5 g, an isotonicite adjuvant: sorbitol in liquid form , in a proportion of 20 to 70 ml, a natural flavor, for example orange cinnamon and a color, for example mint green, all in demineralized water (qs 1 liter).
La préparation ainsi obtenue sera diluée au 1/100 au moment de son emploi et utilisée sous forme topique en bains de bouche ou applications locales ou introduite dans les circuits fluidiques des équipements dentaires. The preparation thus obtained will be diluted 1/100 at the time of its use and used in topical form in mouthwashes or local applications or introduced into the fluid circuits of dental equipment.
Claims (9)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9610672A FR2752731B1 (en) | 1996-08-28 | 1996-08-28 | COMPOSITION USEFUL IN PARTICULAR IN DENTAL SURGERY |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9610672A FR2752731B1 (en) | 1996-08-28 | 1996-08-28 | COMPOSITION USEFUL IN PARTICULAR IN DENTAL SURGERY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2752731A1 true FR2752731A1 (en) | 1998-03-06 |
| FR2752731B1 FR2752731B1 (en) | 2001-04-27 |
Family
ID=9495351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9610672A Expired - Fee Related FR2752731B1 (en) | 1996-08-28 | 1996-08-28 | COMPOSITION USEFUL IN PARTICULAR IN DENTAL SURGERY |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2752731B1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1018337A2 (en) * | 1998-12-11 | 2000-07-12 | Degussa-Hüls Aktiengesellschaft | Formulations containing chlorhexidine, novel chlorhexidine salts,solutions containing the aforesaid chlorhexidine salts and their use |
| FR2791890A1 (en) * | 1999-04-12 | 2000-10-13 | Gilbert Lab | COLORED ALCOHOLIC CHLORHEXIDINE SOLUTION AND MANUFACTURING METHOD THEREOF |
| US6844306B2 (en) * | 2000-10-21 | 2005-01-18 | Degussa Ag | Water-soluble, chlorhexidine-containing compositions and use thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0099209A1 (en) * | 1982-07-01 | 1984-01-25 | JOHNSON & JOHNSON MEDICAL, INC. | Aqueous disinfectant solutions having residual biocidal activity |
| GB2132087A (en) * | 1982-12-10 | 1984-07-04 | Chemical Medic Hall Limited | Germicidal and disinfectant composition |
| DE3331573A1 (en) * | 1983-09-01 | 1985-03-21 | Hans-Werner Dr.rer.nat. 2000 Hamburg Neumann | Antimicrobial agent solution and moist cloth produced with the latter |
| WO1986002090A1 (en) * | 1984-09-26 | 1986-04-10 | Gluck Bruno A | Antiseptic cleansing compositions |
| EP0226081A1 (en) * | 1985-12-02 | 1987-06-24 | Henkel Kommanditgesellschaft auf Aktien | Disinfectant |
| FR2677013A1 (en) * | 1991-06-03 | 1992-12-04 | Rouleau Henri | System for treating water treated as a surgical irrigation liquid |
| EP0639636A2 (en) * | 1993-08-19 | 1995-02-22 | Kao Corporation | Germicidal-disinfectant detergent composition |
-
1996
- 1996-08-28 FR FR9610672A patent/FR2752731B1/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0099209A1 (en) * | 1982-07-01 | 1984-01-25 | JOHNSON & JOHNSON MEDICAL, INC. | Aqueous disinfectant solutions having residual biocidal activity |
| GB2132087A (en) * | 1982-12-10 | 1984-07-04 | Chemical Medic Hall Limited | Germicidal and disinfectant composition |
| DE3331573A1 (en) * | 1983-09-01 | 1985-03-21 | Hans-Werner Dr.rer.nat. 2000 Hamburg Neumann | Antimicrobial agent solution and moist cloth produced with the latter |
| WO1986002090A1 (en) * | 1984-09-26 | 1986-04-10 | Gluck Bruno A | Antiseptic cleansing compositions |
| EP0226081A1 (en) * | 1985-12-02 | 1987-06-24 | Henkel Kommanditgesellschaft auf Aktien | Disinfectant |
| FR2677013A1 (en) * | 1991-06-03 | 1992-12-04 | Rouleau Henri | System for treating water treated as a surgical irrigation liquid |
| EP0639636A2 (en) * | 1993-08-19 | 1995-02-22 | Kao Corporation | Germicidal-disinfectant detergent composition |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1018337A2 (en) * | 1998-12-11 | 2000-07-12 | Degussa-Hüls Aktiengesellschaft | Formulations containing chlorhexidine, novel chlorhexidine salts,solutions containing the aforesaid chlorhexidine salts and their use |
| EP1018337A3 (en) * | 1998-12-11 | 2001-01-03 | Degussa-Hüls Aktiengesellschaft | Formulations containing chlorhexidine, novel chlorhexidine salts,solutions containing the aforesaid chlorhexidine salts and their use |
| US6500466B2 (en) | 1998-12-11 | 2002-12-31 | Degussa Ag | Chlorhexidine formulations, new chlorhexidine salts, solutions containing these and their use |
| FR2791890A1 (en) * | 1999-04-12 | 2000-10-13 | Gilbert Lab | COLORED ALCOHOLIC CHLORHEXIDINE SOLUTION AND MANUFACTURING METHOD THEREOF |
| EP1044686A1 (en) * | 1999-04-12 | 2000-10-18 | Laboratoires Gilbert SA | Alcoholic coloured chlorhexidine solution and its manufacturing process |
| US6844306B2 (en) * | 2000-10-21 | 2005-01-18 | Degussa Ag | Water-soluble, chlorhexidine-containing compositions and use thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2752731B1 (en) | 2001-04-27 |
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| Date | Code | Title | Description |
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| TQ | Partial transmission of property |
Owner name: DAVID MORENO, FR Effective date: 20150119 Owner name: CATHERINE MICHELE FRECHE, FR Effective date: 20150119 |
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| ST | Notification of lapse |
Effective date: 20160429 |