FR2741891B1 - CELLS FOR THE PRODUCTION OF RECOMBINANT ADENOVIRUSES - Google Patents

CELLS FOR THE PRODUCTION OF RECOMBINANT ADENOVIRUSES

Info

Publication number
FR2741891B1
FR2741891B1 FR9506532A FR9506532A FR2741891B1 FR 2741891 B1 FR2741891 B1 FR 2741891B1 FR 9506532 A FR9506532 A FR 9506532A FR 9506532 A FR9506532 A FR 9506532A FR 2741891 B1 FR2741891 B1 FR 2741891B1
Authority
FR
France
Prior art keywords
cells
production
recombinant adenoviruses
adenoviruses
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9506532A
Other languages
French (fr)
Other versions
FR2741891A1 (en
Inventor
Jean Francois Dedieu
Cecile Orsini
Michel Perricaudet
Emmanuelle Vigne
Patrice Yeh
Edouard Prost
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Priority to FR9506532A priority Critical patent/FR2741891B1/en
Priority to IL11681696A priority patent/IL116816A/en
Priority to AU45443/96A priority patent/AU717253B2/en
Priority to BR9606971A priority patent/BR9606971A/en
Priority to MX9704552A priority patent/MX9704552A/en
Priority to US08/875,223 priority patent/US6127175A/en
Priority to CZ19972306A priority patent/CZ294969B6/en
Priority to PCT/FR1996/000088 priority patent/WO1996022378A1/en
Priority to CA002210168A priority patent/CA2210168A1/en
Priority to SK990-97A priority patent/SK99097A3/en
Priority to JP8522091A priority patent/JPH11504502A/en
Priority to KR1019970704903A priority patent/KR100510822B1/en
Priority to HU9702404A priority patent/HU222191B1/en
Priority to EP96901417A priority patent/EP0805868A1/en
Publication of FR2741891A1 publication Critical patent/FR2741891A1/en
Priority to FI973055A priority patent/FI973055A0/en
Priority to NO19973332A priority patent/NO320382B1/en
Application granted granted Critical
Publication of FR2741891B1 publication Critical patent/FR2741891B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10361—Methods of inactivation or attenuation
    • C12N2710/10362—Methods of inactivation or attenuation by genetic engineering
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/60—Vector systems having a special element relevant for transcription from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9506532A 1995-01-20 1995-06-01 CELLS FOR THE PRODUCTION OF RECOMBINANT ADENOVIRUSES Expired - Fee Related FR2741891B1 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR9506532A FR2741891B1 (en) 1995-06-01 1995-06-01 CELLS FOR THE PRODUCTION OF RECOMBINANT ADENOVIRUSES
IL11681696A IL116816A (en) 1995-01-20 1996-01-18 Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
KR1019970704903A KR100510822B1 (en) 1995-01-20 1996-01-19 Cells for Recombinant Adenovirus Production
MX9704552A MX9704552A (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses.
US08/875,223 US6127175A (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses
CZ19972306A CZ294969B6 (en) 1995-01-20 1996-01-19 Cell useful for producing recombinant adenoviruses, plasmid for transformation of such a cell, production process of defective recombinant adenoviruses, defective recombinant adenovirus obtained thereby and use of such a cell for production of recombinant adeno-associated viruses AAV
PCT/FR1996/000088 WO1996022378A1 (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses
CA002210168A CA2210168A1 (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses
AU45443/96A AU717253B2 (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses
JP8522091A JPH11504502A (en) 1995-01-20 1996-01-19 Cells for production of recombinant adenovirus
BR9606971A BR9606971A (en) 1995-01-20 1996-01-19 Cell usable for the production of plasmid defective adenovirus comprising a part of the e4 region of an adenovirus genome using a cell preparation process for defective recombinant adenovirus at least for the e4 region purified defective recombinant adenovirus stock defective adenovirus defective production process recombinant aav
HU9702404A HU222191B1 (en) 1995-01-20 1996-01-19 Cell-line for the production of defective recombinant adenoviruses and processes for production such a viruses
EP96901417A EP0805868A1 (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses
SK990-97A SK99097A3 (en) 1995-01-20 1996-01-19 Cells for the production of recombinant adenoviruses
FI973055A FI973055A0 (en) 1995-01-20 1997-07-18 Cells for production of recombinant adenoviruses
NO19973332A NO320382B1 (en) 1995-01-20 1997-07-18 plasmid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9506532A FR2741891B1 (en) 1995-06-01 1995-06-01 CELLS FOR THE PRODUCTION OF RECOMBINANT ADENOVIRUSES

Publications (2)

Publication Number Publication Date
FR2741891A1 FR2741891A1 (en) 1997-06-06
FR2741891B1 true FR2741891B1 (en) 1998-01-09

Family

ID=9479587

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9506532A Expired - Fee Related FR2741891B1 (en) 1995-01-20 1995-06-01 CELLS FOR THE PRODUCTION OF RECOMBINANT ADENOVIRUSES

Country Status (1)

Country Link
FR (1) FR2741891B1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0673431A1 (en) * 1992-12-03 1995-09-27 Genzyme Corporation Gene therapy for cystic fibrosis
FR2705686B1 (en) * 1993-05-28 1995-08-18 Transgene Sa New defective adenoviruses and corresponding complementation lines.
ES2310924T3 (en) * 1993-07-13 2009-01-16 Centelion DEFECTIVE ADENOVIRAL VECTORS AND USE IN GENE THERAPY.
FR2707664B1 (en) * 1993-07-13 1995-09-29 Centre Nat Rech Scient Viral vectors and use in gene therapy.

Also Published As

Publication number Publication date
FR2741891A1 (en) 1997-06-06

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ST Notification of lapse

Effective date: 20080229