FR2735015A1 - INTERNAL PROSTHESIS IN THE FORM OF A TEXTILE OR OTHER SUPPORT AND ITS COELIOSCOPIC INSERTION DEVICE - Google Patents
INTERNAL PROSTHESIS IN THE FORM OF A TEXTILE OR OTHER SUPPORT AND ITS COELIOSCOPIC INSERTION DEVICE Download PDFInfo
- Publication number
- FR2735015A1 FR2735015A1 FR9507262A FR9507262A FR2735015A1 FR 2735015 A1 FR2735015 A1 FR 2735015A1 FR 9507262 A FR9507262 A FR 9507262A FR 9507262 A FR9507262 A FR 9507262A FR 2735015 A1 FR2735015 A1 FR 2735015A1
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- FR
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- Prior art keywords
- support
- tube
- mandrel
- prosthesis
- prosthesis according
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
- A61F2002/0068—Implantable repair or support meshes, e.g. hernia meshes having a special mesh pattern
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
- A61F2002/0072—Delivery tools therefor
Abstract
Description
Prothèse interne sous forme d'un supPort textile ou autre et son appareil d'insertion Par voie coelioscoPiaue. Internal prosthesis in the form of a textile or other support and its insertion device via coelioscoPiaue.
L'invention se rattache au secteur technique des implants prothétiques notamment pour le traitement des hernies inguinales ou crurales par laparotomie classique ou sous coelioscopie. The invention relates to the technical sector of prosthetic implants in particular for the treatment of inguinal or crural hernias by conventional laparotomy or under laparoscopy.
Pour ce genre d'intervention, on utilise généralement des prothèses sous forme d'un support textile ou autre, tissé ou non tissé, pour servir de renfort aux tissus au niveau desquels ils sont implantés. For this type of intervention, prostheses are generally used in the form of a textile or other support, woven or non-woven, to serve as reinforcement for the tissues in which they are implanted.
Généralement, ces supports sont mis en place comme indiqué, soit par laparotomie, soit par coelioscopie, sur la zone anatomique à traiter en étant fixés aux reliefs fibreux et ostéotendineux de la zone considérée, au moyen de points de suture ou d'agrafes. Generally, these supports are put in place as indicated, either by laparotomy or by laparoscopy, on the anatomical area to be treated by being fixed to the fibrous and osteotendinous reliefs of the area considered, by means of stitches or staples.
Quels que soient les modes de réalisation de ces supports, (tissage, tricotage, extrusion...) ou leurs matériaux constitutifs (polyester, polypropylène, PTFE...) et quelles ques soient leurs formes géométriques (carrée, rectangulaire, en Y...), ces derniers se présentent toujours sous une forme plane, qui ne peut, en conséquent, épouser aucun des reliefs de la région anatomique considérée. Le chirurgien est donc obligé de placer de nombreuses agrafes pour sécuriser l'emplacement de la prothèse, sans être certain de maîtriser leur position exacte, ce qui peut représenter un risque dans le cas notamment d'une mise en place par laparoscopie. Ces nombreuses agrafes nécessaires à la mise en forme de la prothèse restent à demeure, ce qui peut nécessiter une réintervention si l'une ou plusieurs d'entre elles sont mal positionnées. Whatever the embodiments of these supports, (weaving, knitting, extrusion ...) or their constituent materials (polyester, polypropylene, PTFE ...) and whatever their geometric shapes (square, rectangular, Y. ..), the latter are always presented in a flat form, which cannot, therefore, match any of the reliefs of the anatomical region considered. The surgeon is therefore obliged to place numerous staples to secure the location of the prosthesis, without being certain of controlling their exact position, which can represent a risk in the case in particular of a laparoscopic placement. These numerous staples necessary for shaping the prosthesis remain permanently, which may require reintervention if one or more of them are incorrectly positioned.
L'invention s'est fixée pour but de remédier à ces inconvénients, de manière simple, sûre, efficace et rationnelle. The object of the invention is to remedy these drawbacks in a simple, safe, effective and rational manner.
Le problème que se propose de résoudre l'invention est de réaliser une prothèse interne sous forme d'un support souple, dont la géométrie correspond parfaitement à la zone anatomique à traiter, afin de dispenser l'opérateur de toute fixation par agrafes ou autres. The problem which the invention proposes to solve is to produce an internal prosthesis in the form of a flexible support, the geometry of which corresponds perfectly to the anatomical area to be treated, in order to exempt the operator from any fixing by staples or the like.
Pour résoudre un tel problème, il a été conçu et mis au point une prothèse interne sous forme d'un support textile ou autre, tissé ou non tissé, inerte et biocompatible, le support étant soumis, en totalité ou en partie, à un traitement apte à lui donner une forme géométrique prédéterminée correspondant à l'anatomie considérée de la zone à traiter. To solve such a problem, an internal prosthesis has been designed and developed in the form of a textile or other support, woven or non-woven, inert and biocompatible, the support being subjected, in whole or in part, to treatment. able to give it a predetermined geometric shape corresponding to the anatomy considered of the area to be treated.
Un autre problème que se propose de résoudre l'invention, est d'améliorer la maniabilité per-opératoire en chirurgie coelioscopique en vue de sa mise en place au moyen d'un trocart notamment. Another problem which the invention proposes to solve is to improve the operability during surgery in laparoscopic surgery with a view to its installation by means of a trocar in particular.
Pour résoudre un tel problème, le support est traité pour présenter une mémoire de forme résultant de la nature du matériau ou par une rigidité contrôlée dudit matériau afin de pouvoir être enroulé et inserré dans un trocart de coelioscopie notamment, et de s'autodéployer dans une cavité, retrouvant sa forme initiale. To solve such a problem, the support is treated to present a shape memory resulting from the nature of the material or by a controlled rigidity of said material so as to be able to be wound and inserted in a laparoscopic trocar in particular, and to self-deploy in a cavity, returning to its original shape.
Selon une autre caractéristique, la prothèse est enduite d'une substance biologique pour améliorer sa biocompatibilité et son adhésion aux tissus adjacents. According to another characteristic, the prosthesis is coated with a biological substance to improve its biocompatibility and its adhesion to adjacent tissues.
Dans le cas d'une application à une prothèse parietale, la forme géométrique correspond soit à la zone inguino-pelvienne droite pour le traitement des hernies droites, soit à la zone inguino-pelvienne gauche pour le traitement des hernies gauches. In the case of an application to a parietal prosthesis, the geometric shape corresponds either to the right inguino-pelvic zone for the treatment of right hernias, or to the left inguino-pelvic zone for the treatment of left hernias.
Un autre problème que se propose de résoudre l'invention est de faciliter l'introduction de la prothèse dans un trocart. Plus particulièrement, le problème que se propose de résoudre l'invention est de pouvoir enrouler la prothèse en vue de son introduction dans le trocart en opposition aux techniques actuellement utilisées ou généralement, la prothèse doit être enroulée manuellement. Another problem which the invention proposes to solve is to facilitate the introduction of the prosthesis into a trocar. More particularly, the problem which the invention proposes to solve is to be able to wind the prosthesis with a view to its introduction into the trocar in opposition to the techniques currently used or generally, the prosthesis must be wound manually.
Pour résoudre un tel problème, il a été conçu et mis au point un appareil qui est constitué par un mandrin d'enroulement présentant des moyens d'accouplement temporaire du support, ledit mandrin étant logé à l'intérieur d'un tube avec capacité d'entrainement en rotation, ledit tube présentant des agencements pour le pasage du support en vue de son enroulement sur le mandrin qui est démontable par rapport audit tube, pour ne laisser que le support à l'intérieur du tube après séparation du moyen d'accouplement temporaire. To solve such a problem, an apparatus has been designed and developed which consists of a winding mandrel having means for temporarily coupling the support, said mandrel being housed inside a tube with capacity d drive in rotation, said tube having arrangements for the passage of the support for its winding on the mandrel which is removable relative to said tube, to leave only the support inside the tube after separation from the coupling means temporary.
Pour résoudre le problème posé de laisser le support à l'intérieur du tube, les moyens d'accouplement temporaire sont constitués par un ou plusieurs fils permettant de relier le support au mandrin et débordant latéralement par des orifices, le tube étant fendu en totalité ou en partie pour l'engagement dudit support. To solve the problem posed of leaving the support inside the tube, the temporary coupling means consist of one or more wires making it possible to connect the support to the mandrel and projecting laterally through orifices, the tube being split entirely or partly for the engagement of said support.
Pour résoudre le problème posé de procéder à l'enroulement de la prothèse, I'une des extrémités du mandrin présente un embout molleté centré et guidé en rotation à l'une des extrémités du tube dont l'autre extrémité présente un embout fixe. To resolve the problem posed of winding the prosthesis, one of the ends of the mandrel has a centered knurled endpiece which is guided in rotation at one end of the tube, the other end of which has a fixed endpiece.
L'invention est exposée, ci-après plus en détail à laide des dessins annexés, dans lesquels
Les figures 1 et 2 sont des vues d'une forme de réalisation de la prothèse interne tri-dimentionnelle, dans le cas d'une application à une prothèse parietale, la figure 1 montrant la prothèse pour le traitement des hernies droites, tandis que la figure 2 montre la prothèse pour le traitement des hernies gauches.The invention is set out below in more detail using the accompanying drawings, in which
Figures 1 and 2 are views of an embodiment of the internal three-dimensional prosthesis, in the case of an application to a parietal prosthesis, Figure 1 showing the prosthesis for the treatment of straight hernias, while the Figure 2 shows the prosthesis for the treatment of left hernias.
La figure 3 est une vue en perspective avant montage de l'appareil de mise en place de la prothèse. Figure 3 is a perspective view before assembly of the device for placing the prosthesis.
La figure 4 est une vue correspondant à la figure 3 après montage des éléments constitutifs de l'appareil. Figure 4 is a view corresponding to Figure 3 after mounting of the components of the device.
La figure 5 est une vue en coupe longitudinale de l'appareil avant enroulement de la prothèse. Figure 5 is a longitudinal sectional view of the device before winding the prosthesis.
La figure 6 est une vue correspondant à la figure 5, après enroulement de la prothèse autour du mandrin. Figure 6 is a view corresponding to Figure 5, after winding the prosthesis around the mandrel.
La figure 7 est une vue correspondant à la figure 6, après retrait du fil de suture et du mandrin d'enroulement. Figure 7 is a view corresponding to Figure 6, after removal of the suture and the winding mandrel.
La figure 8 est une vue en coupe transversale considérée selon la ligne 8.8 de la figure 7. Figure 8 is a cross-sectional view taken along line 8.8 of Figure 7.
La prothèse tri-dimentionnelle, selon l'invention, est exécutée à partir de tout support (1) textile ou autre, tissé ou non tissé, en étant exécuté en tout type de matériau inerte et bio-compatible. Le support (1) présente généralement une structure maillée, plus ou moins aérée, en fonction du cas pathologique à traiter. A titre d'exemple, le matériau constitutif du support peut être un polymère implantable inerte totalement biocompatible, stérile, apyrogène, non résorbable et à élasticité bidirectionnelle. La structure peut être constituée par un tissu ou un treillis à mailles bloquées, conformé pour ne pas s'effilocher ou se rompre. The three-dimensional prosthesis, according to the invention, is performed from any textile or other support (1), woven or non-woven, by being performed in any type of inert and biocompatible material. The support (1) generally has a mesh structure, more or less ventilated, depending on the pathological case to be treated. By way of example, the material constituting the support may be an inert implantable polymer which is completely biocompatible, sterile, pyrogen-free, non-absorbable and with bidirectional elasticity. The structure can be constituted by a fabric or a mesh with locked meshes, shaped so as not to fray or break.
La structure de base du support, au niveau de sa composition, n'est pas décrite en détail car, comme indiqué, différentes formes de réalisation peuvent être prévues. Cette structure et le matériau constitutif ne font pas partie de l'objet spécifique de l'invention. The basic structure of the support, in terms of its composition, is not described in detail because, as indicated, different embodiments can be provided. This structure and the constituent material are not part of the specific object of the invention.
Selon une caractéristique à la base de l'invention, le support (1) est soumis en totalité ou en partie à un traitement apte à lui donner une forme géométrique prédéterminée (la) correspondant à l'anatomie considérée de la zone à traiter. Dans le cas d'une prothèse parietale, deux formes tridimentionnelles sont prévues pour le traitement respectivement des hernies droites (figure 1) ou des hernies gauches (figures 2). According to a characteristic underlying the invention, the support (1) is subjected in whole or in part to a treatment capable of giving it a predetermined geometric shape (la) corresponding to the anatomy considered of the area to be treated. In the case of a parietal prosthesis, two three-dimensional forms are provided for the treatment respectively of right hernias (FIG. 1) or left hernias (FIGS. 2).
A noter que la forme géométrique tridimentionnelle du support (1) peut être obtenue selon différentes techniques, à savoir par exemple, traitement thermique, thermoformage... Note that the three-dimensional geometric shape of the support (1) can be obtained according to different techniques, namely for example, heat treatment, thermoforming ...
En outre, le support (1) est traité pour présenter une mémoire de forme résultant de la nature du matériau ou par une rigidité contrôlée dudit matériau, afin de pouvoir être enroulé et inserré dans un trocart de coelioscopie notamment et de s'autodéployer dans une cavité en retrouvant sa forme initiale. La mémoire de forme doit être suffisante pour éviter au support de se replier sur lui même lors de sa mise en place, mais au contraire pouvoir se déployer spontanément et naturellement pour épouser parfaitement la région anatomique considérée. L'ensemble du support peut être enduit d'une substance biologique permettant d'améliorer la biocompatibilité de la prothèse, sa recolonnisation par les tissus conjonctifs adjacents. Une telle enduction permet également, par les propriétés adhésives de la substance biologique, d'améliorer la fixation naturelle de la prothèse. In addition, the support (1) is treated to present a shape memory resulting from the nature of the material or by a controlled rigidity of said material, in order to be able to be wound and inserted in a laparoscopic trocar in particular and to self-deploy in a cavity by returning to its original shape. The shape memory must be sufficient to prevent the support from folding back on itself during its installation, but on the contrary being able to deploy spontaneously and naturally to perfectly fit the anatomical region considered. The entire support can be coated with a biological substance making it possible to improve the biocompatibility of the prosthesis, its recolonnization by the adjacent connective tissues. Such a coating also makes it possible, by the adhesive properties of the biological substance, to improve the natural fixation of the prosthesis.
Comme indiqué, un autre problème que se propose de résoudre l'invention est de faciliter l'enroulement de la prothèse et son insertion dans un trocart. A cet égard, il a été conçu et mis au point un appareil qui permet au chirurgien d'enrouler le support (1) et d'inserrer la prothèse dans le trocart, sans être obligé de la toucher. As indicated, another problem which the invention proposes to solve is to facilitate the winding of the prosthesis and its insertion into a trocar. In this regard, an apparatus has been designed and developed which allows the surgeon to wind the support (1) and to insert the prosthesis into the trocar, without having to touch it.
Comme le montrent les figures 3 à 8, L'appareil est constitué essentiellement par un mandrin d'enroulement (2) conformé pour être engagé à l'intérieur d'un tube (3) avec capacité d'entrainement en rotation. As shown in Figures 3 to 8, The device consists essentially of a winding mandrel (2) shaped to be engaged inside a tube (3) with rotational drive capacity.
Le mandrin (2) est démontable par rapport au tube (3). Le tube (3) présente, sur la totalité ou une partie de sa longueur, une fente (3a) pour l'engagement du support (1) à l'intérieur dudit tube. Le tube (3) est fermé d'un côté par un embout fixe (4). L'autre extrémité du tube (3) reçoit le mandrin (2) dont l'une des extrémités présente un embout molleté (2a) centré et guidé en rotation par rapport au tube. Le support (1) est relié au mandrin (2) par un ou plusieurs fils (5). Par exemple, le mandrin (2) est percé coaxialement en (2b) pour l'engagement d'un fil de suture (5) qui déborde alternativement par des orifices (2c) répartis et alignés selon les génératrices du mandrin (2) pour être relié au support (1) (figures 3, 4 et 5).The mandrel (2) is removable relative to the tube (3). The tube (3) has, over all or part of its length, a slot (3a) for the engagement of the support (1) inside said tube. The tube (3) is closed on one side by a fixed end piece (4). The other end of the tube (3) receives the mandrel (2), one of the ends of which has a knurled end piece (2a) centered and guided in rotation relative to the tube. The support (1) is connected to the mandrel (2) by one or more wires (5). For example, the mandrel (2) is pierced coaxially at (2b) for the engagement of a suture thread (5) which alternately extends beyond orifices (2c) distributed and aligned according to the generatrices of the mandrel (2) to be connected to the support (1) (Figures 3, 4 and 5).
L'enroulement de la prothèse, notamment du support (1) à l'intérieur du tube (3), s'effectue par simple rotation de l'embout (2a) du mandrin (2), le tube étant maintenu par l'embout fixe (4). Lorsque le chirurgien commence l'enroulement, le support (1) est déjà engagé dans le tube au travers de la fente (3a), par son bord longitudinal. Lorsque le support est totalement enroulé à l'intérieur du tube (figure 6), il suffit d'exercer une traction sur les brins débordants (5a) et (5b) du fil de suture (5), pour désolidariser d'une manière concomitante, le support (1) du mandrin (2). Le mandrin (2) peut alors être retiré du tube (3), le support (1) restant enroulé à l'intérieur dudit tube (figures 7 et 8). Le chirurgien introduit alors le tube (3) avec la prothèse enroulée dans le trocart. The prosthesis, in particular the support (1) is wound inside the tube (3), is carried out by simple rotation of the end piece (2a) of the mandrel (2), the tube being held by the end piece fixed (4). When the surgeon begins winding, the support (1) is already engaged in the tube through the slot (3a), by its longitudinal edge. When the support is completely wound inside the tube (figure 6), it suffices to exert a traction on the overhanging strands (5a) and (5b) of the suture (5), to disengage in a concomitant manner , the support (1) of the mandrel (2). The mandrel (2) can then be removed from the tube (3), the support (1) remaining wound inside said tube (Figures 7 and 8). The surgeon then introduces the tube (3) with the prosthesis wound in the trocar.
Les avantages ressortent bien de la description, en particulier on souligne et on rappelle:
- La forme tridimentionnelle de la prothèse prédéterminée pour correspondre à l'anatomie de la zone à traiter, évitant l'emploi d'agrafes de positionnement,
- Par sa forme tridimentionnelle et sa rigidité contrôlée, la prothèse anatomique, enroulée au moment de son introduction dans le trocart, peut s'autodéployer, facilitant sa mise en place,
- La facilité d'enroulement de la prothèse et son insertion dans un trocart par l'utilisation de l'appareil spécifique. The advantages clearly emerge from the description, in particular it is emphasized and recalled:
- The three-dimensional shape of the predetermined prosthesis to correspond to the anatomy of the area to be treated, avoiding the use of positioning clips,
- By its three-dimensional shape and controlled rigidity, the anatomical prosthesis, wound at the time of its introduction into the trocar, can self-deploy, facilitating its installation,
- The ease of winding the prosthesis and inserting it into a trocar by using the specific device.
Claims (8)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
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FR9507262A FR2735015B1 (en) | 1995-06-12 | 1995-06-12 | INTERNAL PROSTHESIS IN THE FORM OF A TEXTILE OR OTHER MEDIUM AND ITS COELIOSCOPIC INSERTION APPARATUS |
PCT/FR1996/000850 WO1996041588A1 (en) | 1995-06-12 | 1996-06-06 | Internal prosthesis consisting of a fabric or other substrate, and apparatus for celioscopically inserting same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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FR9507262A FR2735015B1 (en) | 1995-06-12 | 1995-06-12 | INTERNAL PROSTHESIS IN THE FORM OF A TEXTILE OR OTHER MEDIUM AND ITS COELIOSCOPIC INSERTION APPARATUS |
Publications (2)
Publication Number | Publication Date |
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FR2735015A1 true FR2735015A1 (en) | 1996-12-13 |
FR2735015B1 FR2735015B1 (en) | 1998-02-13 |
Family
ID=9480114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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FR9507262A Expired - Fee Related FR2735015B1 (en) | 1995-06-12 | 1995-06-12 | INTERNAL PROSTHESIS IN THE FORM OF A TEXTILE OR OTHER MEDIUM AND ITS COELIOSCOPIC INSERTION APPARATUS |
Country Status (2)
Country | Link |
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FR (1) | FR2735015B1 (en) |
WO (1) | WO1996041588A1 (en) |
Cited By (17)
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WO2001080773A1 (en) * | 2000-04-20 | 2001-11-01 | Ethicon Gmbh | Implant |
WO2002078568A1 (en) * | 2001-03-30 | 2002-10-10 | Mpathy Medical Devices Limited | Surgical implant |
WO2004037123A1 (en) * | 2002-10-18 | 2004-05-06 | Xavier Alfredo F | Prosthetic mesh anchor device |
US6740122B1 (en) | 1998-09-11 | 2004-05-25 | C. R. Bard, Inc. | Preformed curved prosthesis that is adapted to the external iliac vessels |
WO2005044143A1 (en) * | 2003-10-31 | 2005-05-19 | Mpathy Medical Devices Limited | Hernia prosthesis |
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US8529434B2 (en) | 2008-10-29 | 2013-09-10 | Cook Medical Technologies Llc | Endoscopic sheet delivery |
US8668635B2 (en) | 2000-10-12 | 2014-03-11 | Coloplast A/S | Pelvic implant with suspending system |
US8920304B2 (en) | 2000-07-05 | 2014-12-30 | Coloplast A/S | Method and device for treating urinary incontinence |
US9005222B2 (en) | 2002-08-02 | 2015-04-14 | Coloplast A/S | Self-anchoring sling and introducer system |
US9186489B2 (en) | 2003-03-27 | 2015-11-17 | Coloplast A/S | Implantable delivery device system for delivery of a medicament to a bladder |
US11413129B2 (en) | 2020-06-19 | 2022-08-16 | Davol Inc. | Implantable prosthesis |
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FR2767671B1 (en) | 1997-08-27 | 1999-11-26 | Ethnor | PROSTHETIC SHUTTER DEVICE FOR SHUTTERING HERNARY CHANNELS |
US6241768B1 (en) | 1997-08-27 | 2001-06-05 | Ethicon, Inc. | Prosthetic device for the repair of a hernia |
FR2767672B1 (en) * | 1997-08-27 | 1999-11-26 | Ethnor | PROSTHESES FOR SEALING HERNIA CANALS |
US6723133B1 (en) | 1998-09-11 | 2004-04-20 | C. R. Bard, Inc. | Performed curved prosthesis having a reduced incidence of developing wrinkles or folds |
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FR2735015B1 (en) | 1998-02-13 |
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