FR2706889A1 - Use of N-(arylmethylene)ethylenediaminetriacetate, N-(arylmethylene)iminodiacetate or N,N'-di(arylmethylene)ethylenediaminediacetate compounds against oxidative stress - Google Patents

Use of N-(arylmethylene)ethylenediaminetriacetate, N-(arylmethylene)iminodiacetate or N,N'-di(arylmethylene)ethylenediaminediacetate compounds against oxidative stress Download PDF

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FR2706889A1
FR2706889A1 FR9307641A FR9307641A FR2706889A1 FR 2706889 A1 FR2706889 A1 FR 2706889A1 FR 9307641 A FR9307641 A FR 9307641A FR 9307641 A FR9307641 A FR 9307641A FR 2706889 A1 FR2706889 A1 FR 2706889A1
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formula
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acid
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FR9307641A
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English (en)
French (fr)
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FR2706889B1 (OSRAM
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LOreal SA
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LOreal SA
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Priority to FR9307641A priority Critical patent/FR2706889A1/fr
Application filed by LOreal SA filed Critical LOreal SA
Priority to JP51179294A priority patent/JP3510627B2/ja
Priority to DE69326776T priority patent/DE69326776T2/de
Priority to EP94900187A priority patent/EP0668854B1/fr
Priority to US08/436,203 priority patent/US5703095A/en
Priority to PCT/FR1993/001109 priority patent/WO1994011338A1/fr
Priority to ES94900187T priority patent/ES2136723T3/es
Priority to CA002149431A priority patent/CA2149431A1/fr
Priority to AT94900187T priority patent/ATE185548T1/de
Publication of FR2706889A1 publication Critical patent/FR2706889A1/fr
Priority to US08/469,751 priority patent/US5629436A/en
Application granted granted Critical
Publication of FR2706889B1 publication Critical patent/FR2706889B1/fr
Granted legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR9307641A 1992-11-13 1993-06-23 Use of N-(arylmethylene)ethylenediaminetriacetate, N-(arylmethylene)iminodiacetate or N,N'-di(arylmethylene)ethylenediaminediacetate compounds against oxidative stress Granted FR2706889A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
FR9307641A FR2706889A1 (en) 1993-06-23 1993-06-23 Use of N-(arylmethylene)ethylenediaminetriacetate, N-(arylmethylene)iminodiacetate or N,N'-di(arylmethylene)ethylenediaminediacetate compounds against oxidative stress
DE69326776T DE69326776T2 (de) 1992-11-13 1993-11-10 Verwendung von n-arylmethylen ethylendiamintriacetate, n-arylmethylen iminodiacetat oder n,n'-diarylmethylen ethylendiamindiacetat gegen oxidativen stress
EP94900187A EP0668854B1 (fr) 1992-11-13 1993-11-10 Utilisation de n-arylmethylene ethylenediaminetriacetates, n-arylmethylene iminodiacetates ou n,n'-diarylmethylene ethylenediaminacetates contre le stress oxydant
US08/436,203 US5703095A (en) 1992-11-13 1993-11-10 Use of N-arylmethylene, ethylenediaminetriacetates, N-arymethylene iminodiacetates or N,N'-diarylmethylene ethylenediamineacetates against oxidative stress
JP51179294A JP3510627B2 (ja) 1992-11-13 1993-11-10 酸化性ストレスに対するn−アリールメチレンエチレンジアミントリアセテート、n−アリールメチレンイミノジアセテートまたはn,n′−ジアリールメチレンエチレンジアミンアセテートの使用
PCT/FR1993/001109 WO1994011338A1 (fr) 1992-11-13 1993-11-10 Utilisation de n-arylmethylene ethylenediaminetriacetates, n-arylmethylene iminodiacetates ou n,n'-diarylmethylene ethylenediaminacetates contre le stress oxydant
ES94900187T ES2136723T3 (es) 1992-11-13 1993-11-10 Utilizacion de n-aril-metilen-etilen-diamino-triacetatos, n-aril-metilen-imino-diacetatos o n,n'-diaril-metilen-etilen-diamino-acetatos contra el estres oxidante.
CA002149431A CA2149431A1 (fr) 1992-11-13 1993-11-10 Utilisation de n-arylmethylene ethylenediamine-triacetates, de n-arylmethylene iminodiacetates ou de n,n'-diarylmethylene ethylenediaminacetates contre le stress oxydant
AT94900187T ATE185548T1 (de) 1992-11-13 1993-11-10 Verwendung von n-arylmethylen ethylendiamintriacetate, n-arylmethylen iminodiacetat oder n,n'-diarylmethylen ethylendiamindiacetat gegen oxidativen stress
US08/469,751 US5629436A (en) 1992-11-13 1995-06-06 Use of N-arylmethylene ethylenediaminetriacetates N-arylmethylene iminodiacetates or N,N'-diarylmethylene ethylenediamineacetates against oxidative stress

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9307641A FR2706889A1 (en) 1993-06-23 1993-06-23 Use of N-(arylmethylene)ethylenediaminetriacetate, N-(arylmethylene)iminodiacetate or N,N'-di(arylmethylene)ethylenediaminediacetate compounds against oxidative stress

Publications (2)

Publication Number Publication Date
FR2706889A1 true FR2706889A1 (en) 1994-12-30
FR2706889B1 FR2706889B1 (OSRAM) 1995-10-13

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
FR9307641A Granted FR2706889A1 (en) 1992-11-13 1993-06-23 Use of N-(arylmethylene)ethylenediaminetriacetate, N-(arylmethylene)iminodiacetate or N,N'-di(arylmethylene)ethylenediaminediacetate compounds against oxidative stress

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FR (1) FR2706889A1 (OSRAM)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528196A (en) * 1981-02-23 1985-07-09 The United States Of America As Represented By The Department Of Health And Human Services Chelating agents for the treatment of iron overload
EP0367223A2 (en) * 1988-10-31 1990-05-09 The Dow Chemical Company Chelants possessing ortho ligating functionality and complexes thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528196A (en) * 1981-02-23 1985-07-09 The United States Of America As Represented By The Department Of Health And Human Services Chelating agents for the treatment of iron overload
EP0367223A2 (en) * 1988-10-31 1990-05-09 The Dow Chemical Company Chelants possessing ortho ligating functionality and complexes thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
A. E. MARTELL ET AL: "DEVELOPMENT OF IRON CHELATORS FOR COOLEY'S ANEMIA", INORGANICA CHIMICA ACTA, vol. 138, no. 3, 1987, pages 215 - 230 *
BYOUNG-KOOK K.: "EFFECTIVENESS OF ORAL IRON CHELATORS ASSAYED IN THE RAT", AMERICAN JOURNAL OF HEMATOLOGY, vol. 24, no. 3, March 1987 (1987-03-01), pages 277 - 284 *
C.G. PITT ET AL.: "ESTERS AND LACTONES OF PHENOLIC AMINO CARBOXYLIC ACIDS: PRODURUGS FOR IRON CHELATION", JOURNAL OF MEDICINAL CHEMISTRY, vol. 29, no. 7, July 1986 (1986-07-01), WASHINGTON US, pages 1231 - 1237 *
CHEMICAL ABSTRACTS, vol. 110, no. 13, 27 March 1989, Columbus, Ohio, US; abstract no. 110927, LI J ET AL.: "Specific sequestering agents for the actinides VI" page 344; *
CHEMICAL ABSTRACTS, vol. 24, no. 2, 25 January 1960, Columbus, Ohio, US; abstract no. 110927, "12TH COLLECTIVE INDEX CHEMICAL SUBSTANCES:GLYCINE,N,N'-1,2-ETHANEDIYLBIS[N-[(3-HYDROXY-4-4-METHOXYPHENYL)METHYL]-" page 41612CS; *
SHANDONG YIKE DAXUE XUEBAO (SYXBEE); 88; VOL.26 (2); PP.64-8 *

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Publication number Publication date
FR2706889B1 (OSRAM) 1995-10-13

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