FR2704391A1 - Nutritional supplement which can be taken orally to facilitate adaptation to daily stress - Google Patents

Nutritional supplement which can be taken orally to facilitate adaptation to daily stress Download PDF

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Publication number
FR2704391A1
FR2704391A1 FR9305201A FR9305201A FR2704391A1 FR 2704391 A1 FR2704391 A1 FR 2704391A1 FR 9305201 A FR9305201 A FR 9305201A FR 9305201 A FR9305201 A FR 9305201A FR 2704391 A1 FR2704391 A1 FR 2704391A1
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France
Prior art keywords
nutritional supplement
magnesium
stress
facilitate adaptation
daily stress
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Granted
Application number
FR9305201A
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French (fr)
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FR2704391B1 (en
Inventor
Curtay Jean-Paul
Boiron Christian
Abecassis Jacky
Baume Bernard
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Boiron SA
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Boiron SA
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Priority to FR9305201A priority Critical patent/FR2704391B1/en
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Publication of FR2704391B1 publication Critical patent/FR2704391B1/en
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Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15Vitamins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16Inorganic salts, minerals or trace elements
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Nutritional supplement which can be taken orally to facilitate adaptation to daily stress, which contains, in combination, taurine, vitamin B6, magnesium and an excipient.

Description

COMPLEMENT NUTRITIONNEL ABSORBABLE POUR FACILITER
L'ADAPTATION AU STRESS QUOTIDIEN.
ABSORBABLE NUTRITIONAL SUPPLEMENT TO FACILITATE
ADAPTING TO DAILY STRESS.

L'invention concerne un complément nutritionnel absorbable pour faciliter l'adaptation au stress quotidien. The invention relates to an absorbable nutritional supplement to facilitate adaptation to daily stress.

Comme on le sait, la situation de stress résulte d'un débordement des capacités physiologiques d'adaptation face à des situations stressantes. As we know, the stressful situation results from an overflow of physiological capacities to adapt to stressful situations.

Ce débordement survient soit lorsque l'agression est trop forte, soit lorsque les capacités d'adaptation sont affaiblies. Il se traduit essentiellement par un inconfort psychologique, une baisse d'énergie, un affaiblissement des défenses immunitaires face aux infections, de l'aérophagie, des palpitations.This overflow occurs either when the aggression is too strong, or when the adaptive capacities are weakened. It mainly results in psychological discomfort, a drop in energy, a weakening of the immune defenses against infections, aerophagia, palpitations.

De la sorte, pouvoir contrôler le stress est non seulement une façon d'améliorer le confort personnel, mais constitue également une importante mesure de médecine préventive. In this way, being able to control stress is not only a way to improve personal comfort, but also constitutes an important measure of preventive medicine.

L'invention permet d'atteindre ces objectifs. Elle vise un complément nutritionnel absorbable qui se caractérise en ce qu'il contient en association de la taurine, de la vitamine B6, du magnésium et un excipient. The invention achieves these objectives. It targets an absorbable nutritional supplement which is characterized in that it contains in combination with taurine, vitamin B6, magnesium and an excipient.

Par "complément nutritionnel", on désigne un ensemble absorbable formant une supplémentation en micronutriments complétant l'alimentation quotidienne, qui permet à la fois d'agir sur un symptôme et en même temps de renforcer l'organisme.  By "nutritional supplement" is meant an absorbable whole forming a micronutrient supplementation supplementing the daily diet, which allows both to act on a symptom and at the same time to strengthen the body.

Comme on le sait, le magnésium intervient lors de la production de l'énergie. La baisse du niveau d'énergie disponible s'accompagne d'une anxiété qui, elle-même, est consommatrice de magnésium. Ainsi, une personne qui présente des carences en magnésium "hyperréagit" au stress par des manifestations d'intensité disproportionnée augmentant ainsi son déficit en énergie et son anxiété. As we know, magnesium is involved in the production of energy. The drop in the level of available energy is accompanied by anxiety which, itself, consumes magnesium. Thus, a person who has magnesium deficiencies "hyperreacts" to stress by manifestations of disproportionate intensity, thus increasing his energy deficit and his anxiety.

On est donc en présence d'un cercle vicieux, puisque la carence en magnésium engendre le stress et le stress entraîne une carence accrue en magnésium. We are therefore in the presence of a vicious circle, since the magnesium deficiency generates stress and the stress leads to an increased magnesium deficiency.

Avantageusement en pratique, le magnésium se présente sous forme de glycérophosphate de magnésium, plus facile à assimiler. Advantageously in practice, magnesium is in the form of magnesium glycerophosphate, which is easier to assimilate.

La taurine, qui est un acide aminé, présente des propriétés complémentaires de celles du magnésium. Elle diminue l'excitabilité des cellules dans la plupart des organes, tels que le coeur et le cerveau. Elle facilite la fixation du magnésium et tamponne l'excès de calcium intracellulaire. "Ainsi, la taurine compense les effets d'un déficit en magnésium. Taurine, which is an amino acid, has properties complementary to those of magnesium. It decreases the excitability of cells in most organs, such as the heart and the brain. It facilitates the fixation of magnesium and buffers excess intracellular calcium. "Thus, taurine compensates for the effects of a magnesium deficiency.

La vitamine B6 est le co-facteur de la synthèse de la taurine. Elle est également nécessaire à la synthèse du G.A.B.A et de la sérotonine, qui sont deux neuro-transmetteurs anti-anxiogènes. La vitamine B6 n'agit que lorsqu'elle est activée et son activation dépend du magnésium. Vitamin B6 is the co-factor in the synthesis of taurine. It is also necessary for the synthesis of G.A.B.A and serotonin, which are two anti-anxiety neuro-transmitters. Vitamin B6 only works when activated and its activation depends on magnesium.

Ainsi, magnésium, taurine et vitamine B6 agissent en synergie entre eux pour concourrir à une action anti-stress originale.  Thus, magnesium, taurine and vitamin B6 act in synergy between them to contribute to an original anti-stress action.

Comme excipient, on utilise avantageusement du dextrose stabilisé par du stéarate de magnésium et coloré par la poudre de spiruline. As excipient, use is advantageously made of dextrose stabilized with magnesium stearate and colored with spirulina powder.

Dans une forme d'exécution préférée, la composition nutritionnelle caractéristique de l'invention contient en pour cent en poids:
- 80 % de glycérophosphate de magnésium;
- 8,4 % de taurine;
- 0,1 % de vitamine B6;
-11,5 % d'excipient, par exemple:
.9,8% de dextrose; .1 I % de stéarate de magnésium;
.0,7% de poudre de spiruline.
In a preferred embodiment, the nutritional composition characteristic of the invention contains in percent by weight:
- 80% magnesium glycerophosphate;
- 8.4% taurine;
- 0.1% vitamin B6;
-11.5% of excipient, for example:
.9.8% dextrose; .1 I% magnesium stearate;
0.7% spirulina powder.

Pour garantir l'intégrité des différents composés, on effectue avantageusement la formulation de la manière suivante. Dans un premier temps, on granule en phase humide les excipients et les principaux composés. Puis, dans un deuxième temps, on mélange en phase sèche les vitamines et les principes actifs fragiles. To guarantee the integrity of the various compounds, the formulation is advantageously carried out in the following manner. Initially, the excipients and the main compounds are granulated in the wet phase. Then, in a second step, vitamins and fragile active ingredients are mixed in the dry phase.

Le complément nutritionnel selon l'invention peut être absorbé sous forme de poudre, de gélules, de granules, et avantageusement de comprimés. The nutritional supplement according to the invention can be absorbed in the form of powder, capsules, granules, and advantageously tablets.

Ce complément nutritionnel, sous la forme de comprimés de 500 mg, peut être avalé à raison de deux comprimés respectivement le matin et le soir au cours du repas pendant deux à trois mois renouvelables.  This nutritional supplement, in the form of tablets of 500 mg, can be swallowed at the rate of two tablets respectively in the morning and in the evening during the meal for two to three months renewable.

Le complément nutritionnel conforme à l'invention permet avantageusement:
- de faciliter l'adaptation au stress de tous ordres : physiques (surmenage, accident, fracture, opération chirurgicale) et psychologiques (soucis, situations conflictuelles, deuil, etc...) ;
- de compenser la vulnérabilité au stress, la nervosité, l'hyperémotivité, la tendance colérique chez l'enfant et l'adolescent;
- de compenser la vulnérabilité au stress chez la femme, en particulier sous pilule, lorsqu'elle souffre de troubles liés au cycle menstruel ou pendant la grossesse; ;
- de compenser la vulnérabilité au stress liée à la spasmophilie (hyperréactivité, nervosité, troubles du sommeil, fatigabilité, sensations de malaise, gorge serrée, fourmillements, contractures, crampes, tremblements, ballonnements, troubles du transit, palpitations, sueurs, etc..., tous ces symptômes étant en outre aggravés par le stress).
The nutritional supplement according to the invention advantageously allows:
- to facilitate adaptation to stress of all kinds: physical (overwork, accident, fracture, surgical operation) and psychological (worries, conflict situations, mourning, etc.);
- to compensate for vulnerability to stress, nervousness, hyperemotivity, angry tendency in children and adolescents;
- to compensate for the vulnerability to stress in women, in particular on the pill, when they suffer from disorders linked to the menstrual cycle or during pregnancy; ;
- to compensate for the vulnerability to stress linked to spasmophilia (hyperreactivity, nervousness, sleep disturbances, tiredness, feelings of discomfort, tight throat, tingling, contractures, cramps, tremors, bloating, transit disorders, palpitations, sweating, etc.) ., all these symptoms being further aggravated by stress).

Claims (4)

REVENDICATIONS 1/ Complément nutritionnel absorbable pour faciliter l'adaptation au stress quotidien, caractérisé en ce qu'il contient en association de la taurine, de la vitamine B6, du magnésium et un excipient. 1 / Absorbable nutritional supplement to facilitate adaptation to daily stress, characterized in that it contains a combination of taurine, vitamin B6, magnesium and an excipient. 2/ Complément nutritionnel selon la revendication 1, caractérisé en ce que le magnésium se présente sous forme de glycérophosphate de magnésium. 2 / nutritional supplement according to claim 1, characterized in that the magnesium is in the form of magnesium glycerophosphate. 3/ Complément nutritionnel selon la revendication 1, caractérisé en ce que l'excipient est formé par un mélange de dextrose stabilisé par du stéarate de magnésium et coloré par de la poudre de spiruline. 3 / Nutritional supplement according to claim 1, characterized in that the excipient is formed by a mixture of dextrose stabilized by magnesium stearate and colored by spirulina powder. 4/ Complément nutritionnel absorbable pour faciliter l'adaptation au stress quotidien, caractérisé en ce qu'il contient en pour cent en poids: 4 / Absorbable nutritional supplement to facilitate adaptation to daily stress, characterized in that it contains in percent by weight: - 80 % de glycérophosphate de magnésium; - 80% magnesium glycerophosphate; - 8,4 % de taurine; - 8.4% taurine; - 0,1 % de vitamine B6; - 0.1% vitamin B6; - 115 % d'excipient.  - 115% of excipient.
FR9305201A 1993-04-27 1993-04-27 Absorbable nutritional supplement to facilitate adaptation to daily stress. Expired - Fee Related FR2704391B1 (en)

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FR9305201A FR2704391B1 (en) 1993-04-27 1993-04-27 Absorbable nutritional supplement to facilitate adaptation to daily stress.

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Application Number Priority Date Filing Date Title
FR9305201A FR2704391B1 (en) 1993-04-27 1993-04-27 Absorbable nutritional supplement to facilitate adaptation to daily stress.

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FR2704391A1 true FR2704391A1 (en) 1994-11-04
FR2704391B1 FR2704391B1 (en) 1995-06-02

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT409218B (en) * 2000-11-14 2002-06-25 Red Bull Gmbh Use of taurine for improving psychomotor performance and coordination
WO2003013495A1 (en) * 2001-08-08 2003-02-20 Smothers Don L Formulation and method for reduction of stress in meat-producing animals
EP1541041A1 (en) * 2003-12-10 2005-06-15 Synergia Holding Pharmaceutical and/or dietary compositions against stress
CN111315373A (en) * 2017-10-13 2020-06-19 瑟纳法姆工业合成有限公司 Compounds and compositions for the prevention and/or treatment of central nervous system diseases characterized by a decrease in neuronal plasticity, in particular a decrease in synaptic plasticity

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980168A (en) * 1989-10-13 1990-12-25 Natrol, Inc. Dietary supplement for children
WO1991011117A2 (en) * 1990-02-05 1991-08-08 Board Of Regents, The University Of Texas System Dietary supplements comprising vitamins and minerals
WO1993002682A1 (en) * 1991-08-06 1993-02-18 Labco Pharmaceuticals, Inc. Method and compositions for reducing craving for alcohol and stimulants

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980168A (en) * 1989-10-13 1990-12-25 Natrol, Inc. Dietary supplement for children
WO1991011117A2 (en) * 1990-02-05 1991-08-08 Board Of Regents, The University Of Texas System Dietary supplements comprising vitamins and minerals
WO1993002682A1 (en) * 1991-08-06 1993-02-18 Labco Pharmaceuticals, Inc. Method and compositions for reducing craving for alcohol and stimulants

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT409218B (en) * 2000-11-14 2002-06-25 Red Bull Gmbh Use of taurine for improving psychomotor performance and coordination
WO2003013495A1 (en) * 2001-08-08 2003-02-20 Smothers Don L Formulation and method for reduction of stress in meat-producing animals
EP1541041A1 (en) * 2003-12-10 2005-06-15 Synergia Holding Pharmaceutical and/or dietary compositions against stress
FR2863497A1 (en) * 2003-12-10 2005-06-17 Synergia Holding NEW PHARMACEUTICAL AND / OR DIETETIC COMPOSITIONS AGAINST STRESS
CN111315373A (en) * 2017-10-13 2020-06-19 瑟纳法姆工业合成有限公司 Compounds and compositions for the prevention and/or treatment of central nervous system diseases characterized by a decrease in neuronal plasticity, in particular a decrease in synaptic plasticity
US20220008455A1 (en) * 2017-10-13 2022-01-13 Synapharm Industrial Synthesis Compound and Composition for Use in the Preventive and/or Curative Treatment of Diseases of the Central Nervous System Characterised by a Decline in Neuronal Plasticity, in Particular Characterised by a Decline in Synaptic Plasticity

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FR2704391B1 (en) 1995-06-02

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