FR2694767B1 - Anti-IL6R monoclonal antibodies, and their applications. - Google Patents

Anti-IL6R monoclonal antibodies, and their applications.

Info

Publication number
FR2694767B1
FR2694767B1 FR9210005A FR9210005A FR2694767B1 FR 2694767 B1 FR2694767 B1 FR 2694767B1 FR 9210005 A FR9210005 A FR 9210005A FR 9210005 A FR9210005 A FR 9210005A FR 2694767 B1 FR2694767 B1 FR 2694767B1
Authority
FR
France
Prior art keywords
applications
monoclonal antibodies
il6r
il6r monoclonal
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9210005A
Other languages
French (fr)
Other versions
FR2694767A1 (en
Inventor
John Wijdenes
Claude Clement
Delphine Marchand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INNOTHERAPIE LAB SA
Original Assignee
INNOTHERAPIE LAB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INNOTHERAPIE LAB SA filed Critical INNOTHERAPIE LAB SA
Priority to FR9210005A priority Critical patent/FR2694767B1/en
Publication of FR2694767A1 publication Critical patent/FR2694767A1/en
Application granted granted Critical
Publication of FR2694767B1 publication Critical patent/FR2694767B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
FR9210005A 1992-08-13 1992-08-13 Anti-IL6R monoclonal antibodies, and their applications. Expired - Fee Related FR2694767B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9210005A FR2694767B1 (en) 1992-08-13 1992-08-13 Anti-IL6R monoclonal antibodies, and their applications.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9210005A FR2694767B1 (en) 1992-08-13 1992-08-13 Anti-IL6R monoclonal antibodies, and their applications.

Publications (2)

Publication Number Publication Date
FR2694767A1 FR2694767A1 (en) 1994-02-18
FR2694767B1 true FR2694767B1 (en) 1994-10-21

Family

ID=9432845

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9210005A Expired - Fee Related FR2694767B1 (en) 1992-08-13 1992-08-13 Anti-IL6R monoclonal antibodies, and their applications.

Country Status (1)

Country Link
FR (1) FR2694767B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US11851486B2 (en) 2017-05-02 2023-12-26 National Center Of Neurology And Psychiatry Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
AU700819B2 (en) * 1994-10-07 1999-01-14 Chugai Seiyaku Kabushiki Kaisha Rheumatoid arthritis remedy containing IL-6 antagonist as effective component
PL182089B1 (en) * 1994-10-21 2001-11-30 Chugai Pharmaceutical Co Ltd Pharmaceutic compositions for treating diseases caused by production of il-6
EP0811384B1 (en) * 1995-02-13 2006-06-21 Chugai Seiyaku Kabushiki Kaisha Muscle protein decomposition inhibitor containing il-6 receptor antibody
US6217858B1 (en) * 1997-02-11 2001-04-17 Hadasit & Medical Research Services & Development Company, Ltd. Pharmaceutical composition for treating hepatitis B virus (HBV) infection
EP0983767B1 (en) 1997-03-21 2008-09-10 Chugai Seiyaku Kabushiki Kaisha Preventives or remedies for the treatment of multiple sclerosis containing antagonist anti-IL-6-receptor antibodies
AU747883B2 (en) * 1997-08-15 2002-05-30 Chugai Seiyaku Kabushiki Kaisha Preventives and/or remedies for systemic lupus erythematosus containing anti-IL-6 receptor antibody as the active ingredient
UA80091C2 (en) 2001-04-02 2007-08-27 Chugai Pharmaceutical Co Ltd Remedies for infant chronic arthritis-relating diseases and still's disease which contain an interleukin-6 (il-6) antagonist
CN100340294C (en) 2003-02-24 2007-10-03 中外制药株式会社 Remedy for spinal injury containing interleukin-6 antagonist
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
US20070134242A1 (en) 2003-10-17 2007-06-14 Chugai Seiyaku Kabushiki Kaisha Mesothelioma therapeutic agent
AR048210A1 (en) 2003-12-19 2006-04-12 Chugai Pharmaceutical Co Ltd A PREVENTIVE AGENT FOR VASCULITIS.
EP3269738A1 (en) 2004-03-24 2018-01-17 Chugai Seiyaku Kabushiki Kaisha Subtypes of humanized antibody against interleukin-6 receptor
RU2446826C2 (en) 2005-10-14 2012-04-10 Фукуока Юниверсити Agents for suppressing transplanted island damage following island transplantation
EP1941908B1 (en) 2005-10-21 2015-08-19 Chugai Seiyaku Kabushiki Kaisha Therapeutic agent for heart disease
AR057582A1 (en) 2005-11-15 2007-12-05 Nat Hospital Organization AGENTS TO DELETE INDUCTION OF CYTOTOXIC T LYMPHOCYTES
WO2007061029A1 (en) 2005-11-25 2007-05-31 Keio University Therapeutic agent for prostate cancer
EP3135298B1 (en) 2006-01-27 2018-06-06 Keio University Therapeutic agents for diseases involving choroidal neovascularization
EP2025346B1 (en) 2006-04-07 2016-08-10 Osaka University Muscle regeneration promoter
US8080248B2 (en) 2006-06-02 2011-12-20 Regeneron Pharmaceuticals, Inc. Method of treating rheumatoid arthritis with an IL-6R antibody
EP2374818B1 (en) * 2006-06-02 2012-12-19 Regeneron Pharmaceuticals, Inc. High affinity antibodies to human IL-6 receptor
PE20081635A1 (en) 2007-01-23 2009-01-07 Chugai Pharmaceutical Co Ltd AGENTS TO SUPPRESS THE CHRONIC REJECTION REACTION
EP2174667B1 (en) 2007-07-26 2017-01-04 Osaka University Agent for treatment of ophthalmia containing interleukin-6 receptor inhibitor as active ingredient
AU2008308163B2 (en) 2007-10-02 2013-03-21 Chugai Seiyaku Kabushiki Kaisha Therapeutic agents for graft-versus-host disease comprising interleukin 6 receptor inhibitor as active ingredient
TWI528973B (en) 2008-06-05 2016-04-11 Chugai Pharmaceutical Co Ltd Nerve infiltration inhibitor
JO3417B1 (en) 2010-01-08 2019-10-20 Regeneron Pharma Stabilized formulations containing anti-interleukin-6 receptor (il-6r) antibodies
ES2932398T3 (en) 2010-05-28 2023-01-18 Chugai Pharmaceutical Co Ltd Antitumor T cell response enhancer
TWI589299B (en) 2011-10-11 2017-07-01 再生元醫藥公司 Compositions for the treatment of rheumatoid arthritis and methods of using same
JP7235249B2 (en) 2017-10-20 2023-03-08 学校法人兵庫医科大学 Pharmaceutical composition for suppressing postoperative adhesion containing anti-IL-6 receptor antibody
MA54861A (en) 2019-01-31 2021-12-08 Regeneron Pharma ANTI-IL6 RECEPTOR ANTIBODIES FOR TREATING JUVENILE IDIOPATHIC ARTHRITIS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02138993A (en) * 1988-08-05 1990-05-28 Ajinomoto Co Inc Novel monoclonal antibody and hybridoma producing same antibody
US5216128A (en) * 1989-06-01 1993-06-01 Yeda Research And Development Co., Ltd. IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it
ATE144713T1 (en) * 1989-07-20 1996-11-15 Tadamitsu Kishimoto ANTIBODIES TO HUMAN INTERLEUKIN-6 RECEPTOR

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US11851486B2 (en) 2017-05-02 2023-12-26 National Center Of Neurology And Psychiatry Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils

Also Published As

Publication number Publication date
FR2694767A1 (en) 1994-02-18

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Legal Events

Date Code Title Description
ST Notification of lapse
CA Change of address
CD Change of name or company name
CJ Change in legal form
RM Correction of a material error
TP Transmission of property
FC Favourable decision of inpi director general on an application for restauration.
RN Application for restoration
ST Notification of lapse

Effective date: 20120430