FR2693373B1 - Prodrogue apte à libérer en milieu physiologique une oxazolidinone, en particulier la chlorzoxazone, et le cas échéant, un acétamidophénol, en particulier le paracétamol, procédés de fabrication. - Google Patents

Prodrogue apte à libérer en milieu physiologique une oxazolidinone, en particulier la chlorzoxazone, et le cas échéant, un acétamidophénol, en particulier le paracétamol, procédés de fabrication.

Info

Publication number
FR2693373B1
FR2693373B1 FR9208751A FR9208751A FR2693373B1 FR 2693373 B1 FR2693373 B1 FR 2693373B1 FR 9208751 A FR9208751 A FR 9208751A FR 9208751 A FR9208751 A FR 9208751A FR 2693373 B1 FR2693373 B1 FR 2693373B1
Authority
FR
France
Prior art keywords
acetamidophenol
chlorzoxazone
oxazolidinone
releasing
appropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9208751A
Other languages
English (en)
Other versions
FR2693373A1 (fr
Inventor
Alain Vigroux
Laurent Blanchoin
Michel Bergon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Toulouse III Paul Sabatier
Original Assignee
Universite Toulouse III Paul Sabatier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Toulouse III Paul Sabatier filed Critical Universite Toulouse III Paul Sabatier
Priority to FR9208751A priority Critical patent/FR2693373B1/fr
Priority to EP93914828A priority patent/EP0649402A1/fr
Priority to PCT/FR1993/000704 priority patent/WO1994001395A1/fr
Publication of FR2693373A1 publication Critical patent/FR2693373A1/fr
Application granted granted Critical
Publication of FR2693373B1 publication Critical patent/FR2693373B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/58—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/555—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound pre-targeting systems involving an organic compound, other than a peptide, protein or antibody, for targeting specific cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9208751A 1992-07-09 1992-07-09 Prodrogue apte à libérer en milieu physiologique une oxazolidinone, en particulier la chlorzoxazone, et le cas échéant, un acétamidophénol, en particulier le paracétamol, procédés de fabrication. Expired - Fee Related FR2693373B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9208751A FR2693373B1 (fr) 1992-07-09 1992-07-09 Prodrogue apte à libérer en milieu physiologique une oxazolidinone, en particulier la chlorzoxazone, et le cas échéant, un acétamidophénol, en particulier le paracétamol, procédés de fabrication.
EP93914828A EP0649402A1 (fr) 1992-07-09 1993-07-07 Prodrogue apte a liberer une oxazolidinone et le cas echeant un acetamidophenol
PCT/FR1993/000704 WO1994001395A1 (fr) 1992-07-09 1993-07-07 Prodrogue apte a liberer une oxazolidinone et le cas echeant un acetamidophenol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9208751A FR2693373B1 (fr) 1992-07-09 1992-07-09 Prodrogue apte à libérer en milieu physiologique une oxazolidinone, en particulier la chlorzoxazone, et le cas échéant, un acétamidophénol, en particulier le paracétamol, procédés de fabrication.

Publications (2)

Publication Number Publication Date
FR2693373A1 FR2693373A1 (fr) 1994-01-14
FR2693373B1 true FR2693373B1 (fr) 1994-10-07

Family

ID=9431918

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9208751A Expired - Fee Related FR2693373B1 (fr) 1992-07-09 1992-07-09 Prodrogue apte à libérer en milieu physiologique une oxazolidinone, en particulier la chlorzoxazone, et le cas échéant, un acétamidophénol, en particulier le paracétamol, procédés de fabrication.

Country Status (3)

Country Link
EP (1) EP0649402A1 (fr)
FR (1) FR2693373B1 (fr)
WO (1) WO1994001395A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002360555A1 (en) * 2001-12-10 2003-06-23 Control Delivery Systems Inc. Treatment of genitourinary tract disorders
WO2005009480A2 (fr) * 2003-06-11 2005-02-03 Control Delivery Systems, Inc. Traitement de troubles de l'appareil genito-urinaire

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660465A (en) * 1969-08-01 1972-05-02 Stauffer Chemical Co Ethynylene containing n-phenyl carbamates
US3657319A (en) * 1970-05-05 1972-04-18 Smith Kline French Lab Alpha-aminoalkyl-4-hydroxy-3-carboalkoxyaminobenzyl alcohols
DE2924089A1 (de) * 1979-06-15 1981-01-08 Henkel Kgaa Neue kupplerkomponenten fuer oxidationshaarfarben, deren herstellung sowie diese enthaltende haarfaerbemittel

Also Published As

Publication number Publication date
EP0649402A1 (fr) 1995-04-26
FR2693373A1 (fr) 1994-01-14
WO1994001395A1 (fr) 1994-01-20

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Legal Events

Date Code Title Description
ST Notification of lapse