FR2692894B1 - Aryl-1- (o-alkoxy-phenyl-4-piperazinyl-1) -2, 3- or 4-alkanols, process for their preparation and their use for the preparation of medicaments. - Google Patents

Aryl-1- (o-alkoxy-phenyl-4-piperazinyl-1) -2, 3- or 4-alkanols, process for their preparation and their use for the preparation of medicaments.

Info

Publication number
FR2692894B1
FR2692894B1 FR9207750A FR9207750A FR2692894B1 FR 2692894 B1 FR2692894 B1 FR 2692894B1 FR 9207750 A FR9207750 A FR 9207750A FR 9207750 A FR9207750 A FR 9207750A FR 2692894 B1 FR2692894 B1 FR 2692894B1
Authority
FR
France
Prior art keywords
preparation
alkanols
piperazinyl
medicaments
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9207750A
Other languages
French (fr)
Other versions
FR2692894A1 (en
Inventor
Patrick Houziaux
Patrick Riffaud Jean-Pierresau
Bernard Danree
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IRCEBA
Original Assignee
IRCEBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IRCEBA filed Critical IRCEBA
Priority to FR9207750A priority Critical patent/FR2692894B1/en
Priority to JP6502107A priority patent/JPH07508728A/en
Priority to CA002139116A priority patent/CA2139116A1/en
Priority to EP93913186A priority patent/EP0647221A1/en
Priority to PCT/FR1993/000633 priority patent/WO1994000442A1/en
Publication of FR2692894A1 publication Critical patent/FR2692894A1/en
Application granted granted Critical
Publication of FR2692894B1 publication Critical patent/FR2692894B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
FR9207750A 1992-06-24 1992-06-24 Aryl-1- (o-alkoxy-phenyl-4-piperazinyl-1) -2, 3- or 4-alkanols, process for their preparation and their use for the preparation of medicaments. Expired - Fee Related FR2692894B1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR9207750A FR2692894B1 (en) 1992-06-24 1992-06-24 Aryl-1- (o-alkoxy-phenyl-4-piperazinyl-1) -2, 3- or 4-alkanols, process for their preparation and their use for the preparation of medicaments.
JP6502107A JPH07508728A (en) 1992-06-24 1993-06-24 1-Allyl(4-o-alkoxyphenyl 1-piperazinyl)-2, -3 or -4 alkanols and methods of their preparation and use thereof in the preparation of drugs.
CA002139116A CA2139116A1 (en) 1992-06-24 1993-06-24 1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 or -4 alcanols, their preparation and their use for the preparation of medications
EP93913186A EP0647221A1 (en) 1992-06-24 1993-06-24 1-aryl(4-o-alkoxyphenyl 1-piperazinyl)-2, -3 or -4 alkanols, process for their preparation and use thereof in the preparation of drugs
PCT/FR1993/000633 WO1994000442A1 (en) 1992-06-24 1993-06-24 1-aryl(4-o-alkoxyphenyl 1-piperazinyl)-2, -3 or -4 alkanols, process for their preparation and use thereof in the preparation of drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9207750A FR2692894B1 (en) 1992-06-24 1992-06-24 Aryl-1- (o-alkoxy-phenyl-4-piperazinyl-1) -2, 3- or 4-alkanols, process for their preparation and their use for the preparation of medicaments.

Publications (2)

Publication Number Publication Date
FR2692894A1 FR2692894A1 (en) 1993-12-31
FR2692894B1 true FR2692894B1 (en) 1994-10-14

Family

ID=9431140

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9207750A Expired - Fee Related FR2692894B1 (en) 1992-06-24 1992-06-24 Aryl-1- (o-alkoxy-phenyl-4-piperazinyl-1) -2, 3- or 4-alkanols, process for their preparation and their use for the preparation of medicaments.

Country Status (5)

Country Link
EP (1) EP0647221A1 (en)
JP (1) JPH07508728A (en)
CA (1) CA2139116A1 (en)
FR (1) FR2692894B1 (en)
WO (1) WO1994000442A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0984777B1 (en) * 1997-05-12 2003-09-17 Ortho-Mcneil Pharmaceutical, Inc. Arylsubstituted piperazines useful in the treatement of benign prostatic hyperlasia
KR100698400B1 (en) * 2004-04-14 2007-03-23 이은주 Pharmaceutical composition for treating hair loss and benign prostatic hyperplasia
CA2562801C (en) * 2004-04-14 2010-09-07 Eun-Joo Lee Pharmaceutical composition for treating hair loss and benign prostatic hyperplasia

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1458905A (en) * 1959-03-26 1966-04-29 Process for the preparation of 1-aralkyl-4-arylpiperazines
US2997474A (en) * 1959-10-12 1961-08-22 Paul A J Janssen 1-aryl-omega-(4-arylpiperazine) alkanols
FR1332560A (en) * 1961-03-20 1963-07-19 Ciba Geigy Process for the preparation of diaza-cyclo-alkanes, inter alia 1- [3-ethoxy-3- (4-methyl-phenyl) -propyl] -3-methyl-4-phenyl-piperazine and its salts
FR1483416A (en) * 1965-06-16 1967-06-02 Science Union Et Compagnie Process for the preparation of new piperazino-phenylethanol derivatives
BE758380A (en) * 1969-11-04 1971-04-16 Sumitomo Chemical Co PROCESS FOR PREPARATION OF ARYL-KETON DERIVATIVES
DE69033100T2 (en) * 1989-04-22 2000-01-05 Wyeth John & Brother Ltd Piperazine derivatives
CA2015033C (en) * 1989-04-22 2000-06-06 American Home Products Corporation Tertiary alkyl functionalized piperazine derivatives
GB9021453D0 (en) * 1990-10-03 1990-11-14 Wyeth John & Brother Ltd Piperazine derivatives

Also Published As

Publication number Publication date
JPH07508728A (en) 1995-09-28
WO1994000442A1 (en) 1994-01-06
CA2139116A1 (en) 1994-01-06
FR2692894A1 (en) 1993-12-31
EP0647221A1 (en) 1995-04-12

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Legal Events

Date Code Title Description
ST Notification of lapse