FR2668931B1 - Utilisation antivirale de compose 2,6-di-t-butylphenol substitue en position 4, notamment vis-a-vis de l'herpes. - Google Patents

Utilisation antivirale de compose 2,6-di-t-butylphenol substitue en position 4, notamment vis-a-vis de l'herpes.

Info

Publication number
FR2668931B1
FR2668931B1 FR9013984A FR9013984A FR2668931B1 FR 2668931 B1 FR2668931 B1 FR 2668931B1 FR 9013984 A FR9013984 A FR 9013984A FR 9013984 A FR9013984 A FR 9013984A FR 2668931 B1 FR2668931 B1 FR 2668931B1
Authority
FR
France
Prior art keywords
compound
particularly against
against herpes
antiviral use
butylphenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9013984A
Other languages
English (en)
Other versions
FR2668931A1 (fr
Inventor
Robert Vachy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fileco
Original Assignee
Fileco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fileco filed Critical Fileco
Priority to FR9013984A priority Critical patent/FR2668931B1/fr
Priority to AU90209/91A priority patent/AU9020991A/en
Priority to PCT/FR1991/000882 priority patent/WO1992008450A2/fr
Priority to DE69119605T priority patent/DE69119605D1/de
Priority to US08/050,279 priority patent/US5487893A/en
Priority to EP91920899A priority patent/EP0557404B1/fr
Publication of FR2668931A1 publication Critical patent/FR2668931A1/fr
Application granted granted Critical
Publication of FR2668931B1 publication Critical patent/FR2668931B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/02Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
    • C07C39/11Alkylated hydroxy benzenes containing also acyclically bound hydroxy groups, e.g. saligenol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/11Aldehydes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/56Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
    • C07C47/565Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/88Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9013984A 1990-11-12 1990-11-12 Utilisation antivirale de compose 2,6-di-t-butylphenol substitue en position 4, notamment vis-a-vis de l'herpes. Expired - Lifetime FR2668931B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9013984A FR2668931B1 (fr) 1990-11-12 1990-11-12 Utilisation antivirale de compose 2,6-di-t-butylphenol substitue en position 4, notamment vis-a-vis de l'herpes.
AU90209/91A AU9020991A (en) 1990-11-12 1991-11-12 Antiviral use of a 2,6-di-t-butylphenol compound substituted in position 4, particularly in relation to herpesviruses and papillomaviruses
PCT/FR1991/000882 WO1992008450A2 (fr) 1990-11-12 1991-11-12 UTILISATION ANTIVIRALE DE COMPOSE 2,6-DI-t-BUTYLPHENOL SUBSTITUE EN POSITION 4, NOTAMMENT VIS-A-VIS DES VIRUS DE L'HERPES ET DES PAPILLOMAVIRUS
DE69119605T DE69119605D1 (de) 1990-11-12 1991-11-12 Antivirale verwendung einer in position-4 substituierten 2,6-di-t-butylphenolverbindung, besonders gegen herpes- und papillomaviren
US08/050,279 US5487893A (en) 1990-11-12 1991-11-12 Antiviral use of a 2,6-di-t-butylphenol compound substituted in 4 position against herpes viruses and papillomaviruses
EP91920899A EP0557404B1 (fr) 1990-11-12 1991-11-12 UTILISATION ANTIVIRALE DE COMPOSE 2,6-DI-t-BUTYLPHENOL SUBSTITUE EN POSITION 4, NOTAMMENT VIS-A-VIS DES VIRUS DE L'HERPES ET DES PAPILLOMAVIRUS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9013984A FR2668931B1 (fr) 1990-11-12 1990-11-12 Utilisation antivirale de compose 2,6-di-t-butylphenol substitue en position 4, notamment vis-a-vis de l'herpes.

Publications (2)

Publication Number Publication Date
FR2668931A1 FR2668931A1 (fr) 1992-05-15
FR2668931B1 true FR2668931B1 (fr) 1995-02-03

Family

ID=9402063

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9013984A Expired - Lifetime FR2668931B1 (fr) 1990-11-12 1990-11-12 Utilisation antivirale de compose 2,6-di-t-butylphenol substitue en position 4, notamment vis-a-vis de l'herpes.

Country Status (1)

Country Link
FR (1) FR2668931B1 (fr)

Also Published As

Publication number Publication date
FR2668931A1 (fr) 1992-05-15

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