FR2662360B1 - COMPOUNDS FOR INCLUDING NIMESULIDE WITH CYCLODEXTRIN, METHODS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY CONTAINING THE SAME. - Google Patents
COMPOUNDS FOR INCLUDING NIMESULIDE WITH CYCLODEXTRIN, METHODS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY CONTAINING THE SAME.Info
- Publication number
- FR2662360B1 FR2662360B1 FR9106165A FR9106165A FR2662360B1 FR 2662360 B1 FR2662360 B1 FR 2662360B1 FR 9106165 A FR9106165 A FR 9106165A FR 9106165 A FR9106165 A FR 9106165A FR 2662360 B1 FR2662360 B1 FR 2662360B1
- Authority
- FR
- France
- Prior art keywords
- analgesic
- cyclodextrin
- compounds
- preparation
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229920000858 Cyclodextrin Polymers 0.000 title 1
- 230000000202 analgesic effect Effects 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- HYWYRSMBCFDLJT-UHFFFAOYSA-N nimesulide Chemical compound CS(=O)(=O)NC1=CC=C([N+]([O-])=O)C=C1OC1=CC=CC=C1 HYWYRSMBCFDLJT-UHFFFAOYSA-N 0.000 title 1
- 229960000965 nimesulide Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9001566A ES2023552A6 (en) | 1990-05-22 | 1990-05-22 | Nimesulid inclusion cpds. with cyclodextrin - more water-soluble with improved bio-availability than nimesulid alone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2662360A1 FR2662360A1 (en) | 1991-11-29 |
| FR2662360B1 true FR2662360B1 (en) | 1993-07-30 |
Family
ID=8267635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9106165A Expired - Fee Related FR2662360B1 (en) | 1990-05-22 | 1991-05-22 | COMPOUNDS FOR INCLUDING NIMESULIDE WITH CYCLODEXTRIN, METHODS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS WITH ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY CONTAINING THE SAME. |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE4116659C2 (en) |
| ES (1) | ES2023552A6 (en) |
| FR (1) | FR2662360B1 (en) |
| IT (1) | IT1255982B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1255462B (en) * | 1992-07-28 | 1995-11-02 | Grazia Maffione | METHOD OF PREPARATION OF NIMESULIDE INCLUSION COMPOUNDS WITH CYCLODESTRINE |
| IT1291278B1 (en) * | 1996-07-05 | 1999-01-07 | Errekappa Euroterapici S P A | NIMESULIDE-BASED PHARMACEUTICAL PREPARATION FOR TOPICAL USE |
| IN186315B (en) * | 1996-12-12 | 2001-08-04 | Panacea Biotec Ltd | |
| IT1291895B1 (en) * | 1997-04-24 | 1999-01-21 | Errekappa Euroterapici S P A | FLUID PHARMACEUTICAL PREPARATION BASED ON NIMESULIDE FOR ORAL AND RHINOPHARYNGAL USE |
| CA2649620A1 (en) * | 2006-04-24 | 2007-11-01 | Panacea Biotec Ltd. | Novel low dose pharmaceutical compositions comprising nimesulide, preparation and use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR206496A1 (en) * | 1972-07-03 | 1976-07-30 | Riker Laboratories Inc | PROCEDURE FOR THE PREPARATION OF 2-PHENOXY-4-NITRO-ALKYL OR HALOALKYLSULPHONANILIDES |
| GB8613688D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
-
1990
- 1990-05-22 ES ES9001566A patent/ES2023552A6/en not_active Expired - Fee Related
-
1991
- 1991-05-21 IT ITMI911396A patent/IT1255982B/en active IP Right Grant
- 1991-05-22 FR FR9106165A patent/FR2662360B1/en not_active Expired - Fee Related
- 1991-05-22 DE DE4116659A patent/DE4116659C2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2023552A6 (en) | 1992-01-16 |
| DE4116659A1 (en) | 1991-11-28 |
| DE4116659C2 (en) | 2000-11-16 |
| ITMI911396A1 (en) | 1992-11-21 |
| FR2662360A1 (en) | 1991-11-29 |
| IT1255982B (en) | 1995-11-17 |
| ITMI911396A0 (en) | 1991-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse | ||
| TP | Transmission of property | ||
| ST | Notification of lapse |
Effective date: 20060131 |