FR2659966B1 - N-ARALKYL GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM. - Google Patents

N-ARALKYL GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Info

Publication number
FR2659966B1
FR2659966B1 FR9003838A FR9003838A FR2659966B1 FR 2659966 B1 FR2659966 B1 FR 2659966B1 FR 9003838 A FR9003838 A FR 9003838A FR 9003838 A FR9003838 A FR 9003838A FR 2659966 B1 FR2659966 B1 FR 2659966B1
Authority
FR
France
Prior art keywords
aralkyl
preparation
products containing
medicinal products
glycinamide derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9003838A
Other languages
French (fr)
Other versions
FR2659966A1 (en
Inventor
Bourzat Jean-Dominique
Capet Marc
Cotrel Claude
Guyon Claude
Manfre Franco
Roussel Gerard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9003838A priority Critical patent/FR2659966B1/en
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Priority to AU74541/91A priority patent/AU650261B2/en
Priority to CA002074357A priority patent/CA2074357A1/en
Priority to EP91905834A priority patent/EP0518961A1/en
Priority to PCT/FR1991/000175 priority patent/WO1991013874A1/en
Priority to HU9202864A priority patent/HU210581B/en
Priority to JP3505782A priority patent/JPH05504968A/en
Priority to NZ237339A priority patent/NZ237339A/en
Priority to IE074591A priority patent/IE910745A1/en
Priority to IL97475A priority patent/IL97475A0/en
Priority to PT96970A priority patent/PT96970A/en
Publication of FR2659966A1 publication Critical patent/FR2659966A1/en
Application granted granted Critical
Publication of FR2659966B1 publication Critical patent/FR2659966B1/en
Priority to NO92923457A priority patent/NO923457L/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/42—Benzopyrazines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
FR9003838A 1990-03-07 1990-03-26 N-ARALKYL GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM. Expired - Lifetime FR2659966B1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR9003838A FR2659966B1 (en) 1990-03-26 1990-03-26 N-ARALKYL GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
CA002074357A CA2074357A1 (en) 1990-03-07 1991-03-05 Glucinamid derivatives, their preparation and drugs containing them
EP91905834A EP0518961A1 (en) 1990-03-07 1991-03-05 Derivatives of glycinamide, their preparation and medicaments containing them
PCT/FR1991/000175 WO1991013874A1 (en) 1990-03-07 1991-03-05 Derivatives of glycinamide, their preparation and medicaments containing them
HU9202864A HU210581B (en) 1990-03-07 1991-03-05 Process for prep. of glycinamide deriv.s and pharmaceutical compn.s contg. them
JP3505782A JPH05504968A (en) 1990-03-07 1991-03-05 Glycinamide derivatives, their production and pharmaceuticals containing them
AU74541/91A AU650261B2 (en) 1990-03-07 1991-03-05 Derivatives of glycinamide, their preparation and medicaments containing them
NZ237339A NZ237339A (en) 1990-03-07 1991-03-06 Glycinamide derivatives, their preparation and pharmaceutical compositions containing them
IE074591A IE910745A1 (en) 1990-03-07 1991-03-06 Glycinamide derivatives, their preparation, pharmaceutical¹compositions containing them, and their use
IL97475A IL97475A0 (en) 1990-03-07 1991-03-07 Glycinamide derivatives,their preparation,pharmaceutical compositions containing them,and their application
PT96970A PT96970A (en) 1990-03-07 1991-03-07 PREPARATION PROCEDURE OF GLYCINAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
NO92923457A NO923457L (en) 1990-03-07 1992-09-04 GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THE DERIVATIVES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9003838A FR2659966B1 (en) 1990-03-26 1990-03-26 N-ARALKYL GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
FR2659966A1 FR2659966A1 (en) 1991-09-27
FR2659966B1 true FR2659966B1 (en) 1992-05-22

Family

ID=9395115

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9003838A Expired - Lifetime FR2659966B1 (en) 1990-03-07 1990-03-26 N-ARALKYL GLYCINAMIDE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Country Status (1)

Country Link
FR (1) FR2659966B1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166355A2 (en) * 1984-06-26 1986-01-02 Merck & Co. Inc. Substituted aminophenyl compounds and acylaminophenyl compounds and pharmaceutical compositions containing them
US4814463A (en) * 1985-12-31 1989-03-21 Biomeasure, Inc. CCK antagonists
CA1326108C (en) * 1988-04-12 1994-01-11 Sun Hyuk Kim Cck antagonists

Also Published As

Publication number Publication date
FR2659966A1 (en) 1991-09-27

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Legal Events

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