FR2649702B1 - ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM - Google Patents

ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM

Info

Publication number
FR2649702B1
FR2649702B1 FR8909481A FR8909481A FR2649702B1 FR 2649702 B1 FR2649702 B1 FR 2649702B1 FR 8909481 A FR8909481 A FR 8909481A FR 8909481 A FR8909481 A FR 8909481A FR 2649702 B1 FR2649702 B1 FR 2649702B1
Authority
FR
France
Prior art keywords
processes
alkylimino
preparation
medicaments containing
benzothiazoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8909481A
Other languages
French (fr)
Other versions
FR2649702A1 (en
Inventor
Patrick Jimonet
Conception Nemecek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Priority to FR8909481A priority Critical patent/FR2649702B1/en
Priority to US07/545,822 priority patent/US5068238A/en
Priority to EP90401974A priority patent/EP0408437B1/en
Priority to AT90401974T priority patent/ATE106878T1/en
Priority to ES90401974T priority patent/ES2055365T3/en
Priority to DK90401974.2T priority patent/DK0408437T3/en
Priority to DE69009604T priority patent/DE69009604T2/en
Priority to JP2182892A priority patent/JPH0352878A/en
Priority to CA002021032A priority patent/CA2021032A1/en
Publication of FR2649702A1 publication Critical patent/FR2649702A1/en
Application granted granted Critical
Publication of FR2649702B1 publication Critical patent/FR2649702B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Compounds of formula: (I) R1 represents a polyfluoroalkoxy radical, R2 represents an alkylthioalkyl, alkylsulphinylalkyl or alkylsulphonylalkyl radical, and R3 represents an alkyl radical, as well as the salts of these compounds with an inorganic or organic acid, processes for preparing them and medicinal products containing them.
FR8909481A 1989-07-13 1989-07-13 ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Expired - Lifetime FR2649702B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR8909481A FR2649702B1 (en) 1989-07-13 1989-07-13 ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM
US07/545,822 US5068238A (en) 1989-07-13 1990-06-29 2-alkyliminobenzothiazoline derivatives, processes for preparing them and medicinal products containing them
AT90401974T ATE106878T1 (en) 1989-07-13 1990-07-09 2-ALKYLIMINOBENZOTHIAZOLINES, THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM.
ES90401974T ES2055365T3 (en) 1989-07-13 1990-07-09 DERIVATIVES OF ALKYLIMINO-2 BENZOTIAZOLINE, ITS PREPARATION PROCEDURES AND THE MEDICINES THAT CONTAIN THEM.
EP90401974A EP0408437B1 (en) 1989-07-13 1990-07-09 2 Alkylimino-benzothiazolines, process for their preparation and pharmaceuticals containing them
DK90401974.2T DK0408437T3 (en) 1989-07-13 1990-07-09 2-Alkyliminobenzothiazoline derivatives, processes for their preparation, and drugs containing these compounds
DE69009604T DE69009604T2 (en) 1989-07-13 1990-07-09 2-alkyliminobenzothiazolines, their preparation and medicaments containing them.
JP2182892A JPH0352878A (en) 1989-07-13 1990-07-12 2-alkyliminobenzothiazoline derivative, preparation thereof, and drug containing same
CA002021032A CA2021032A1 (en) 1989-07-13 1990-07-12 Alkylimino-2-benzothiazoline derivatives, process for their preparation and medicaments containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8909481A FR2649702B1 (en) 1989-07-13 1989-07-13 ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM

Publications (2)

Publication Number Publication Date
FR2649702A1 FR2649702A1 (en) 1991-01-18
FR2649702B1 true FR2649702B1 (en) 1991-11-22

Family

ID=9383777

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8909481A Expired - Lifetime FR2649702B1 (en) 1989-07-13 1989-07-13 ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM

Country Status (9)

Country Link
US (1) US5068238A (en)
EP (1) EP0408437B1 (en)
JP (1) JPH0352878A (en)
AT (1) ATE106878T1 (en)
CA (1) CA2021032A1 (en)
DE (1) DE69009604T2 (en)
DK (1) DK0408437T3 (en)
ES (1) ES2055365T3 (en)
FR (1) FR2649702B1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2688138B1 (en) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa APPLICATION OF AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE TO OBTAIN A MEDICINE FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS.
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
KR20000036227A (en) 1996-09-27 2000-06-26 토마스 씨. 서 Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
CN107007598B (en) * 2017-03-31 2019-06-21 西北工业大学 2- (N- ethyl) -6- trifluoromethoxy benzo thiazole is preparing the application in anticancer drug

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492258A1 (en) * 1980-10-17 1982-04-23 Pharmindustrie NEW AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE-BASED MEDICINAL PRODUCT
CH667091A5 (en) * 1986-09-11 1988-09-15 Lonza Ag N-Substd. 2-imino-benzothiazoline prodn. - from the unsubstd. deriv. and amine in presence of acidic catalyst
DE3721940A1 (en) * 1987-07-02 1989-01-12 Ibm Deutschland REMOVAL OF PARTICLES FROM SURFACES OF SOLID BODY BY LASER Bombardment
FR2649701B2 (en) * 1988-12-15 1991-11-22 Rhone Poulenc Sante IMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM

Also Published As

Publication number Publication date
FR2649702A1 (en) 1991-01-18
ATE106878T1 (en) 1994-06-15
ES2055365T3 (en) 1994-08-16
CA2021032A1 (en) 1991-01-14
JPH0352878A (en) 1991-03-07
EP0408437A3 (en) 1991-05-08
EP0408437B1 (en) 1994-06-08
DE69009604T2 (en) 1994-09-29
DE69009604D1 (en) 1994-07-14
EP0408437A2 (en) 1991-01-16
DK0408437T3 (en) 1994-07-04
US5068238A (en) 1991-11-26

Similar Documents

Publication Publication Date Title
DE10199003I1 (en) Substituted thiazolidine ion derivatives
DE69006984T2 (en) Thiazolidinedione derivatives.
FR2429593A1 (en) DRUGS CONTAINING IMIDAZOLE DERIVATIVES
DE69016899D1 (en) Thiazolidinedione derivatives.
ES2071510T3 (en) DERIVATIVES OF PIRROLIDINE AND THIAZOLIDINE, THEIR PREPARATION AND THE MEDICINES CONTAINING THEM.
FR2599740B1 (en) BENZO (B) THIOPHENE DERIVATIVES OF BENZO (B) FURANNECARBOXAMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM
MA21528A1 (en) SUBSTITUTE COMPONENTS OF FLAVONOIDE, THEIR SALTS, THEIR MANUFACTURES AND PRODUCTS CONTAINING THESE MATERIALS.
OA07257A (en) (Oxo-4-4h- (1) -benzopyran-8-yl) alkanoic acids, salts and derivatives, preparation and medicaments containing them.
FR2558837B1 (en) METHYLENEDIPHOSPHONIC ACID DERIVATIVES, PROCESS FOR OBTAINING SAME AND ANTIRHUMATISMAL DRUGS CONTAINING THEM
FR2649702B1 (en) ALKYLIMINO-2 BENZOTHIAZOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM
FR2612517B1 (en) BENZOXAZINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FI853233A0 (en) 1,6-NAPHTHYRIDE DERIVATIVES, FOERFARANDE FOER DERAS FRAMSTAELLNING OCH DESSA INNEHAOLLANDE PHARMACEUTICAL PRODUCT.
FR2381781A1 (en) GUANINE DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING THESE SUBSTANCES
FR2678619B1 (en) DERIVATIVES OF 1,2,4-THIADIAZOLO [3,4-B] BENZOTHIAZOLE, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
PT76861A (en) PROCESS FOR THE PREPARATION OF NOVEL OXAZINOBENZOTHIAZINE-6,6-DIOXIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
DE3676378D1 (en) ISOXAZOLE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
FR2470110B1 (en) DECRAPENYLAMINE DERIVATIVES, THEIR ACID ADDING SALTS AND PHARMACEUTICAL COMPOSITION CONTAINING THESE PRODUCTS
FI903531A0 (en) Process for the preparation of 2-imino-3-heterocyclylalkylbenzothiatezoline derivatives useful as a drug
DK168284A (en) TROPON DERIVATIVES
IL59358A (en) Hydroxytetrahydro(phenoxymethyl)-imidazothiazole and thiazolopyrimidine derivatives,their preparation and pharmaceutical compositions containing them
MX9204220A (en) BENZIMIDAZOLES.
FR2671081B1 (en) DERIVATIVES OF IMINO-2 POLYFLUOROALKYL-6 HETEROCYCLYLALKYL-3 BENZOTHIAZOLINE, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
DE3784883D1 (en) MACROID COMPOUNDS CONTAINING FLUOR, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE FOR THE PRODUCTION OF MEDICINAL PRODUCTS.
ATE1585T1 (en) CLAVULAN ACID DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.

Legal Events

Date Code Title Description
ST Notification of lapse
ST Notification of lapse
ST Notification of lapse