FR2648714A1 - Reperfusion machine - Google Patents
Reperfusion machine Download PDFInfo
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- FR2648714A1 FR2648714A1 FR8908443A FR8908443A FR2648714A1 FR 2648714 A1 FR2648714 A1 FR 2648714A1 FR 8908443 A FR8908443 A FR 8908443A FR 8908443 A FR8908443 A FR 8908443A FR 2648714 A1 FR2648714 A1 FR 2648714A1
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- Prior art keywords
- mixture
- reperfusion
- machine
- sensor
- pump
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3607—Regulation parameters
- A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
- A61M1/361—Physical characteristics of the blood, e.g. haematocrit, urea before treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3613—Reperfusion, e.g. of the coronary vessels, e.g. retroperfusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0001—Catheters; Hollow probes for pressure measurement
- A61M2025/0003—Catheters; Hollow probes for pressure measurement having an additional lumen transmitting fluid pressure to the outside for measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3344—Measuring or controlling pressure at the body treatment site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3355—Controlling downstream pump pressure
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
Description
MACHINE DE REPERFUSION
La présente invention concerne une machine de reperfusion d'un organe ayant été momentanément ma irrigué par le sang.REPERFUSION MACHINE
The present invention relates to a machine for reperfusion of an organ that has been temporarily irrigated by blood.
Cet organe sera le pius souvent le coeur mais pourra également etre un rein ou le cerveau, oar exemple. This organ will often be the heart, but may also be a kidney or the brain, for example.
La description pui suit se rapporte au cas .e cius fréquent, c'est-à-dire à une insuffisance de ia circulation coronaire. The description which follows relates to the frequent case, that is to say an insufficiency of the coronary circulation.
Une telle insuffisance pourra suivre u infarctus ou bien résulter du prélèvement de l'organe en vue d'une greffe. Such insufficiency may follow an infarction or result from the removal of the organ for transplant.
Dans tous les cas, aorès une insuffisance de la circulation coronaire. il est nécessaire de rétablir ladite circulation de manière progressive et très contrôlée. In all cases, after insufficient coronary circulation. it is necessary to restore said circulation gradually and very controlled.
En effet, les cellules ne supportent oas une oxygénation troD brutale après un état ischémiaue. il est donc indispensable d'assurer un contrôle très strict de l'irrigation en fonction de paramètres tels que la quantité, la température, ou l'oxygénation du sang injecté. In fact, the cells do not support brutal troD oxygenation after an ischemic state. It is therefore essential to ensure very strict control of irrigation according to parameters such as the quantity, temperature, or oxygenation of the blood injected.
Il est de plus nécessaire d'adapter le traitement selon l'état clinique du patient et d'ajouter éventuellement des médicaments au sang injecté afin d'améliorer encore la qualité du traitement. It is moreover necessary to adapt the treatment according to the clinical condition of the patient and possibly to add drugs to the injected blood in order to further improve the quality of the treatment.
Le document EP-A- 192 575 décrit une pompe de perfusion coronaire, pour assistance théraoeutique temporaire en cas d'insuffisance de la circulation coronaire, comportant une sonde munie d'un ballonnet gonflable destiné à fixer l'extrémité de la sonde cans l'artère coronaire, une Dompe susceptible d' injecter oar l'intermédiaire de la sonne du sang oxygéné et éventuellement des drogues, la pompe stant placée sous le contr@le d'un svnchronisateur autorisant l'injection de sang essentiellement pendant la période diastolique du cvcle cardiaaue. Document EP-A-192 575 describes a coronary perfusion pump, for temporary therapeutic assistance in the event of insufficient coronary circulation, comprising a probe fitted with an inflatable balloon intended to fix the end of the probe cans coronary artery, a pump capable of injecting or through the ring of oxygenated blood and possibly drugs, the pump being placed under the control of a synchronizer authorizing the injection of blood essentially during the diastolic period of the cycle cardiac.
L'objectif poursuivi dans ce document est d'assurer l'injection de sang oxygene lorsque les signaux de pression dans l'aorte et d'électrocardiographie sont en coïncidence en un point défini du cycle cardiaque. The objective pursued in this document is to ensure the injection of oxygen blood when the signals of pressure in the aorta and of electrocardiography are in coincidence at a defined point of the cardiac cycle.
Cette notion de coïncidence de signaux ne s'est pas révélée esentielle, et la notion de sang oxygéné doit etre nuancée. This notion of coincidence of signals has not proved essential, and the notion of oxygenated blood must be qualified.
On comprend aisément qu'il est difficilement
Dossibie a l'équipe médicale de suivre de manière constante l'évolution de tous les paramètres et d'agir afin de modifier de manière Drécise chacun desdits paramètres au cours d'une reperfusion qui oeut durer auelaues heures ou quelques jours.It is easy to understand that it is difficult
Dossibie has the medical team to constantly monitor the evolution of all parameters and to act in order to modify in a precise manner each of said parameters during a reperfusion which can last for hours or a few days.
A cet effet, la présente invention propose une machine pour piloter une reserfusion caractérisée en ce au'elle communique avec une banque de données afin de définir un protocole à mettre en oeuvre en fonction de paramètres qu'elle reçoit soit de l'équipe médicale, soit de cateurs permettant d'assurer le suivi en temDs réel de la reoerfusicn. To this end, the present invention provides a machine for controlling a reserfusion characterized in that it communicates with a database in order to define a protocol to be implemented according to parameters which it receives either from the medical team, or cators to ensure real-time monitoring of the reoerfusicn.
Suivant une disposition avantageuse de l'invention, l'équipe médicale peut à tout moment intervenir pour modifier le protocole établi par la machine en cas de conditions particulières. According to an advantageous provision of the invention, the medical team can at any time intervene to modify the protocol established by the machine in the event of particular conditions.
La banque de données permettant l'établissement du protocole a' mettre en oeuvre prend en compte des paramètres concernant par exemple l'age, le poids. certains antécédents et l'état du malade aue l'équipe medicale fournit à la machine a l'aide d'un termina; informatique. Le terminal est en liaison avec le microprocesseur contenant la bancue de donnees. The database allowing the establishment of the protocol to be implemented takes into account parameters relating for example to age and weight. certain history and condition of the patient to the medical team supplied to the machine using a termina; computer science. The terminal is linked to the microprocessor containing the data bank.
Le microprocesseur reçoit également des mesure, en provenance de lusieurs capteurs situés en plusieur@ points du dispositif de reperfusion. The microprocessor also receives measurements, coming from several sensors located at several points of the reperfusion device.
La reperfusion est un traitement qui @erme@ d'irriguer de manière progressive des @ones avant su@@ une insuffisance de circulation par exemple à la suite d'un rétrécissement de l'artère coronaire. The reperfusion is a treatment which @ erme @ to irrigate in a progressive way of the @ones before su @@ an insufficiency of circulation for example following a narrowing of the coronary artery.
A cet effet, un cathéter muni d'un ball@n gonflable est introduit dans l'artère coronaire en aval du retrécissement. On gonfle alors le ballon afin de couper toute relation entre la partie malade située en aval et la partie de l'artère coronaire située en amont dudit ballon. Puis, on fait arriver par le cathéter un mélange comportant du sang et si nécessaire des médicaments sous forme de perfusat,
Grâce à la présence du ballon gonflé pour couper la circulation dans l'artère, on est sûr de la quantité et de la qualité du mélange irrigant la partie malade.To this end, a catheter fitted with an inflatable ball @ n is introduced into the coronary artery downstream of the narrowing. The balloon is then inflated in order to cut off any relationship between the diseased part situated downstream and the part of the coronary artery situated upstream of said balloon. Then a mixture comprising blood and, if necessary, medicines in the form of perfusate, is brought in through the catheter.
Thanks to the presence of the inflated balloon to cut circulation in the artery, we are sure of the quantity and the quality of the mixture irrigating the diseased part.
Ledit mélange ne doit pas etre trop oxygéné afin de ne pas détruire la partie malade. c'est pourquoi on utilise un mélange de sang veineux et de sang artériel prélevés directement sur le malade, ou obtenus par transfusion de sang compatible@
Ce mélange sanguin est b'en entendu strictement dosé puis, il est amené à une température convenable avant d'être introduit cons le cathéter à une pression convenable.Said mixture should not be too oxygenated so as not to destroy the diseased part. this is why we use a mixture of venous blood and arterial blood taken directly from the patient, or obtained by compatible blood transfusion @
This blood mixture is of course strictly dosed then it is brought to a suitable temperature before being introduced cons the catheter at a suitable pressure.
Selon l'invention. c' est la machine cui, par le microprocesseur. détermi ne et contrôle la teneur et débit du mélange. According to the invention. it is the machine cui, by the microprocessor. determine and control the content and flow of the mixture.
A cet effet, des capteurs fournissent b la@ite machine la valeur du débit de sang après le mélange sang veineux-sang artériel, la valeur du oH et de la quantité d'oxygene dudit mélange. To this end, sensors supply the machine with the value of the blood flow after the venous blood-arterial blood mixture, the value of OH and the quantity of oxygen of said mixture.
D'autres capteurs donnent des informations sur le mélange sang t médicaments er. ce qui concerne sa température, la présence ou non oe bulles, la pression dudit mélange. Other sensors provide information on the blood and drug mix. as regards its temperature, the presence or absence of bubbles, the pressure of said mixture.
La machine reçoit encore l'indication de la valeur de la pression coronarienne c'est-à-dire celle à l'extrémité distale du cathéter. The machine also receives an indication of the value of the coronary pressure, that is to say that at the distal end of the catheter.
A partir de ces informations, la ma@@ine éta@lit le protocole du traitement Dis ilote ces pom@es volumétriques assurant l'approvisionnement en sang veineux et en sang artériel, une pompe e@@ou un pousse seringue assurant l'approvisionnemnt en médicaments, la température du fluide assurant par échange de chaleur dans un échangeur thermique une modification de la température du mélange sang/médicament qui va être envoyé dans le cathéter, la machine pilote également une pompe dite principale qui assure la circulation ces mélanges dans le circuit et la pression. On the basis of this information, the ma @@ ine established the treatment protocol. Dis ilote these volumetric pumps ensuring the supply of venous blood and arterial blood, an e @@ pump or a syringe pump ensuring the supply. in medicaments, the temperature of the fluid ensuring by heat exchange in a heat exchanger a modification of the temperature of the blood / medicament mixture which will be sent into the catheter, the machine also controls a so-called main pump which ensures the circulation of these mixtures in the circuit and pressure.
La presente invention sera mieux comprise à la lecture de la description qui va suivre du dessin sur lequel
- la figure 1 montre le circuit de reperfusion
- la figure 2 montre le circuit de traitement
des informations
- la figure 3 montre l'écran de visualisation
mis à la disposition de l'équipe médicale,
La figure 1 montre le circuit dans lecuel circule et est traité le mélange destine ò à être injecté dans l'artère coronaire en direction de la zone malade à travers le cathéter 1.The present invention will be better understood on reading the description which follows of the drawing on which
- Figure 1 shows the reperfusion circuit
- Figure 2 shows the processing circuit
informations
- Figure 3 shows the display screen
made available to the medical team,
Figure 1 shows the circuit in which circulates and is treated the mixture intended to be injected into the coronary artery towards the diseased area through the catheter 1.
Dans l'exemple représente le cathéter . est ur. cathéter à trois lumieres c'est-à-dire b trois canaux longitudinaux internes. In the example represents the catheter. is ur. three lumen catheter i.e. b three internal longitudinal channels.
L'un desdits canaux dont l'entrée est en 11 permet d'insuffler de l'air pour gonfler le ballon destine à fermer la circulation dans l'artère malade,
En variante, le cathéter 1 pourrait ne comporter que deux canaux internes. le canal d'amenée d'air au ballon pouvant être exterieur.One of said channels, the inlet of which is at 11, makes it possible to breathe air to inflate the balloon intended to close the circulation in the diseased artery,
Alternatively, the catheter 1 could have only two internal channels. the air supply channel to the balloon can be external.
Le second canai, le canai 12 assure la circulation du mélange de reperfusion vers l'intérieur de l'artère coronaire. The second channel, channel 12 ensures the circulation of the reperfusion mixture towards the interior of the coronary artery.
Le troisième canal, le canal 13 est un canal par lequel on mesure la pression coronarienne, c'est à dire la pression régnant à l'extrémité distale dudit cathéter, & à l'intérieur de l'artère coronaire. The third channel, channel 13 is a channel by which the coronary pressure is measured, that is to say the pressure prevailing at the distal end of said catheter, & inside the coronary artery.
Ladite pression est mesuree par un capteur de pression 2. la mesure est envoyée après traitement vers: la carte d'acquisition ces données cue comporte Le machine. Said pressure is measured by a pressure sensor 2. the measurement is sent after processing to: the data acquisition card cue includes The machine.
Le sang du malade, ou dans certains cas du sang extérieur. est introduit dans ie circuit par les pompe 31, 32. The patient's blood, or in some cases external blood. is introduced into the circuit by the pumps 31, 32.
La pompe 31 assure l'arrivée de sang veineux, tandis aue la pompe 32 assure l'arrivée de sang arté@iel@ Ces deux pompes sont des pompes volumétriques. The pump 31 ensures the arrival of venous blood, while the pump 32 ensures the arrival of arterial blood @ iel @ These two pumps are volumetric pumps.
Les sangs provenant des deux pompes sont mélangés et envoyés dans la tubulure 4. The blood from the two pumps is mixed and sent to tubing 4.
Ladite tubulure 4 traverse tout d'abord un capteur de débit 5 assurant la mesure du débit par effet DopDler et envcyant la mesure vers la carte d'acquisition. Said tubing 4 first passes through a flow sensor 5 ensuring the measurement of the flow by DopDler effect and envcyant the measurement to the acquisition card.
Le mélange sanguin est ensuite soumis à de capteurs 6, 7 assurant la mesure de la auantito d'oxygène qu'il renferme et de son pH. The blood mixture is then subjected to sensors 6, 7 ensuring the measurement of the amount of oxygen it contains and its pH.
Une pompe 33, dite pompe principale, assure la circulation du mélange sanguin dans la tubulure 4 et donc maintient une pression dans cette tubulure. Ladite pression dans la tubulure est mesurée par un capteur 10 situe près de l'entrée du cathéter. A pump 33, called the main pump, ensures the circulation of the blood mixture in the tubing 4 and therefore maintains a pressure in this tubing. Said pressure in the tubing is measured by a sensor 10 located near the entrance to the catheter.
Un capteur 3 à mesure optique Dermet ce connaftre la vitesse de rotation de la oompe principale 33. La tubulure 4 traverse également un échangeur thermique 8 dans lequel sa température est mesurée par une thermistance 81 et modifiée en fonction de la temperature d'un second fluide traversant l'échangeur. A sensor 3 with optical measurement Dermet ce connaftre the speed of rotation of the main pump 33. The tube 4 also passes through a heat exchanger 8 in which its temperature is measured by a thermistor 81 and modified as a function of the temperature of a second fluid crossing the exchanger.
Le circuit comporte en outre un détecteur de bulles 9. The circuit also includes a bubble detector 9.
Par une branche drivée du circuit on apporte au mélange sanguin, si nécessaire, des médicaments à cet effet, on disDose d'une pompe 34 de perfusion du médicament et d'un Dousse-seringue électrique 20@
Sur la figure 1 on a symoolisé par une flèche double les informations données par les différents capteurs au microprocesseur b travers Le carte d'acquisition, @es fléches simples svmbolisent quant à elles les ordres donnés par ledit microprocesseur à certains recepteurs. Ces ordres sont transmis aux pompes afin d'ajuster leurs vitesses de rotation et donc le volume qu elles deplacent ; l'échangeur thermique 8 et le pousse-seringue 2 reçoivent euxaussi des ordres.Via a branch branch of the circuit, drugs for this purpose are supplied to the blood mixture, if necessary, a pump 34 for infusion of the drug and an electric syringe pump 20 @ are provided.
In FIG. 1, the information given by the various sensors to the microprocessor has been symoolized by a double arrow through the acquisition card, @ the simple arrows symbolize the orders given by said microprocessor to certain receivers. These orders are transmitted to the pumps in order to adjust their rotation speeds and therefore the volume they move; the heat exchanger 8 and the syringe pump 2 also receive orders.
Le figure 2 représente schématiquement l'installation électronique et informatique. FIG. 2 schematically represents the electronic and computer installation.
On retrouve tous les capteurs précédemment décrits et les arrivées de leurs informations à la carte d'acquisition 5. We find all the sensors described above and the arrivals of their information to the acquisition card 5.
Ladite carte analogique 5 reçoit également des informations en provenance d'un électrocardiographe (ECG) 4 non représenté dont les électrodes ont été préalablement positionnées sur le malade. Said analog card 5 also receives information from an electrocardiograph (ECG) 4, not shown, the electrodes of which have been previously positioned on the patient.
On a représenté en 51 le ciavier par lequel l'équipe médicale peut apporter b la machine les renseignements cliniques concernant le malade qui sont nécessaires aux choix du protocole de reperfusion. The keyboard is represented in 51 by which the medical team can bring to the machine the clinical information concerning the patient which is necessary for the choice of the reperfusion protocol.
Toutes les informations sont ainsi amenées au micro-ordinateur 52 aui comporte une banque de données permettant de définir le protocole de reperfusion à appliquer. All the information is thus brought to the microcomputer 52 which has a database making it possible to define the reperfusion protocol to be applied.
Ledit micro-ordinateur 52 pilote alors les pompes, l'échangeur thermique et le Pousse-seringue afin d'administrer au malade la cuentité de sang qui lui est nécessaire. à la bonne température. au bon dosage, avec les bons médicaments et sous la bonne pression. Said microcomputer 52 then controls the pumps, the heat exchanger and the syringe pump in order to administer to the patient the quantity of blood which is necessary for him. at the right temperature. at the right dosage, with the right drugs and under the right pressure.
Toutes les acquisitions se faisant de manière continue, le micro-ordinateur peut modifier le protocole en fonction de l'évolution de l'état du malade. All the acquisitions being made continuously, the microcomputer can modify the protocol according to the evolution of the patient's condition.
Le micro-ordinateur est relié à une imprimante permettant l'établissement informatisé du compte-rendu opératoire, et b un écran de visualisation 53. Tel aue représente à la figure 3, l'écran de visualisation regroupe de nomoreuses donnees et permet à l' écuipe médicalede suivre la reperfusion et l'état du malade. The microcomputer is connected to a printer allowing the computerized establishment of the operating report, and to a display screen 53. As shown in FIG. 3, the display screen groups together large amounts of data and allows the medical team to monitor reperfusion and the patient's condition.
L'équipe médicale peut intervenir à tout moment afin de modifier le protocole piloté oar le micrc ordinateur en donnant des instructions Der l'intermédiaire du clavier 51. The medical team can intervene at any time to modify the protocol controlled by the computer by giving instructions via the keyboard 51.
Une telle machine assure un suivi parfait de Le reperfusion b tout instant. Des alarmes sont bien entendu prévues afin de prévenir l'équipe médicale de toute anomalie dans le fonctionnement de la machine ou dans l'évolution de l'état du malade. Such a machine ensures perfect monitoring of Le reperfusion b at all times. Alarms are of course provided to warn the medical team of any anomaly in the operation of the machine or in the evolution of the patient's condition.
La machine selon l'inventionh n'est pas très encombrante, la tubulure 4 et tous les éléments qui l'entourent peuvent être places sur un plateau afin d'être aisément transportables, le micro-ordinateur et ses périphéries sont eux aussi peu encombrants. On peut aunsi positionner la machine sur une sorte de table rouiante afin ce la manipuler aisément. Si bescin est, on peut également prévoir @ue le support de la machine soit pourvu de batteries afin de rendre la machine totalement autonome. The machine according to the invention is not very bulky, the tubing 4 and all the elements which surround it can be placed on a tray in order to be easily transportable, the microcomputer and its peripheries are also not very bulky. You can also place the machine on a sort of rolling table so that it can be easily manipulated. If necessary, provision can also be made for the support of the machine to be provided with batteries in order to make the machine completely autonomous.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8908443A FR2648714A1 (en) | 1989-06-26 | 1989-06-26 | Reperfusion machine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8908443A FR2648714A1 (en) | 1989-06-26 | 1989-06-26 | Reperfusion machine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2648714A1 true FR2648714A1 (en) | 1990-12-28 |
Family
ID=9383099
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8908443A Withdrawn FR2648714A1 (en) | 1989-06-26 | 1989-06-26 | Reperfusion machine |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2648714A1 (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991012036A1 (en) * | 1990-02-06 | 1991-08-22 | Friedhelm Beyersdorf | Reperfusion device |
| EP1684845A1 (en) * | 2003-10-16 | 2006-08-02 | Neil J. Thomas | Method and apparatus for controlled reoxygenation |
| US8562585B2 (en) | 2008-07-17 | 2013-10-22 | Rheoxtech, Llc | Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention |
| US8888737B2 (en) | 2009-10-20 | 2014-11-18 | Rheoxtech, Llc | Method and apparatus for cardiac tissue monitoring and catheter-based perfusion for mitigating acute reoxygenation injury |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3675640A (en) * | 1970-04-09 | 1972-07-11 | Gatts J D | Method and apparatus for dynamic health testing evaluation and treatment |
| FR2502499A1 (en) * | 1981-03-27 | 1982-10-01 | Farcot Jean Christian | APPARATUS FOR BLOOD RETROPERFUSION, PARTICULARLY FOR THE TREATMENT OF INFARCTUS BY ARTERIAL BLOOD INJECTION IN CORONARY SINUS |
| US4401431A (en) * | 1981-06-26 | 1983-08-30 | Arp Leon J | Blood pump and oxygenator monitor-controller and display device |
| EP0192575A1 (en) * | 1985-02-20 | 1986-08-27 | Medicorp Research Laboratories Corporation | Coronary perfusion pump |
| EP0297723A2 (en) * | 1987-05-29 | 1989-01-04 | Retroperfusion Systems, Inc. | Retroperfusion and retroinfusion control apparatus, system and method |
-
1989
- 1989-06-26 FR FR8908443A patent/FR2648714A1/en not_active Withdrawn
Patent Citations (5)
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991012036A1 (en) * | 1990-02-06 | 1991-08-22 | Friedhelm Beyersdorf | Reperfusion device |
| US5800374A (en) * | 1990-02-06 | 1998-09-01 | Beyersdorf; Friedhelm | Reperfusion device |
| US8178041B2 (en) | 2003-10-16 | 2012-05-15 | Rheoxtech, Llc | Method and apparatus for controlled reoxygenation |
| EP1684845A4 (en) * | 2003-10-16 | 2007-06-06 | Neil J Thomas | Method and apparatus for controlled reoxygenation |
| US7455812B2 (en) | 2003-10-16 | 2008-11-25 | Rheoxtech, Llc | Method and apparatus for controlled reoxygenation |
| US7708942B2 (en) | 2003-10-16 | 2010-05-04 | Rheoxtech, Llc | Method and apparatus for controlled reoxygenation |
| EP1684845A1 (en) * | 2003-10-16 | 2006-08-02 | Neil J. Thomas | Method and apparatus for controlled reoxygenation |
| US8709343B2 (en) | 2003-10-16 | 2014-04-29 | Rheoxtech, Llc | Method and apparatus for controlled reoxygenation |
| US9211371B2 (en) | 2003-10-16 | 2015-12-15 | Rheoxtech, Llc | Method and apparatus for controlled reoxygenation |
| US8562585B2 (en) | 2008-07-17 | 2013-10-22 | Rheoxtech, Llc | Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention |
| US9084856B2 (en) | 2008-07-17 | 2015-07-21 | Rheoxtech, Llc | Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention |
| US9504779B2 (en) | 2008-07-17 | 2016-11-29 | Rheoxtech, Llc | Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention |
| US9775940B2 (en) | 2008-07-17 | 2017-10-03 | Rheoxtech, Llc | Method and apparatus for mitigating acute reoxygenation injury during percutaneous coronary intervention |
| US8888737B2 (en) | 2009-10-20 | 2014-11-18 | Rheoxtech, Llc | Method and apparatus for cardiac tissue monitoring and catheter-based perfusion for mitigating acute reoxygenation injury |
| US9623167B2 (en) | 2009-10-20 | 2017-04-18 | Rheoxtech, Llc | Method and apparatus for cardiac tissue monitoring and catheter-based perfusion for mitigating acute reoxygenation injury |
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