FR2592650A1 - New phenylnaphthyridines functionalised in position 3, process for their preparation, and medicaments which contain them, especially antiulcer medicaments - Google Patents

New phenylnaphthyridines functionalised in position 3, process for their preparation, and medicaments which contain them, especially antiulcer medicaments

Info

Publication number
FR2592650A1
FR2592650A1 FR8600103A FR8600103A FR2592650A1 FR 2592650 A1 FR2592650 A1 FR 2592650A1 FR 8600103 A FR8600103 A FR 8600103A FR 8600103 A FR8600103 A FR 8600103A FR 2592650 A1 FR2592650 A1 FR 2592650A1
Authority
FR
France
Prior art keywords
medicaments
chain
contain
phenylnaphthyridines
antiulcer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8600103A
Other languages
French (fr)
Other versions
FR2592650B1 (en
Inventor
Jean-Marie Teulon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carpibem SA
Original Assignee
Carpibem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carpibem SA filed Critical Carpibem SA
Priority to FR8600103A priority Critical patent/FR2592650B1/en
Priority to NZ218774A priority patent/NZ218774A/en
Priority to AU67023/86A priority patent/AU592396B2/en
Priority to ES86402949T priority patent/ES2042506T3/en
Priority to AT86402949T priority patent/ATE78478T1/en
Priority to DE8686402949T priority patent/DE3686149T2/en
Priority to EP86402949A priority patent/EP0231709B1/en
Priority to KR1019860011598A priority patent/KR900004830B1/en
Priority to PT84049A priority patent/PT84049B/en
Priority to DK002787A priority patent/DK2787A/en
Priority to PH34691A priority patent/PH24700A/en
Publication of FR2592650A1 publication Critical patent/FR2592650A1/en
Application granted granted Critical
Publication of FR2592650B1 publication Critical patent/FR2592650B1/en
Priority to GR920402053T priority patent/GR3005730T3/el
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Products of formula: in which - X: represents a hydrogen atom, an alkyl or cycloalkyl radical, a halogen, a methoxy, a thiomethyl or a nitro and can be in position 5, 6 or 7 of the naphthyridine. - Y can be: an alkenyl or an alkynyl a chain -(CH2)n-S-(CH2)m-CH3 or -(CH2)n-S-(CH2)m-CH3 (n and m being numbers between 0 and 5) a chain (CH2)n-O-(CH2)m-CH3 (n and m defined as above) a chain -(CH2)n-OH or one of its esters (n defined as above) a chain -(CH2)n-CHOH-(CH2)m-CH3 or one of its esters (n and m defined as above) a chain -(CH2)n-CO-(CH2)m-CH3 (n and m defined as above) a phenyl, pyridyl, thiophene or furan ring. - Z and W represent a hydrogen atom, a halogen, a lower alkyl group containing 1 to 5 carbon atoms, a methoxy, a thiomethyl, a trifluoromethyl, a nitro, a cyano or an alkylcyano, - and the medicaments which contain them.
FR8600103A 1986-01-06 1986-01-06 NOVEL PHENYL-NAPHTYRIDINES FUNCTIONALIZED IN POSITION-3, THEIR PREPARATION PROCESS, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS. Expired FR2592650B1 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8600103A FR2592650B1 (en) 1986-01-06 1986-01-06 NOVEL PHENYL-NAPHTYRIDINES FUNCTIONALIZED IN POSITION-3, THEIR PREPARATION PROCESS, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS.
NZ218774A NZ218774A (en) 1986-01-06 1986-12-23 3-substituted phenylnaphthyridines and pharmaceutical compositions
AU67023/86A AU592396B2 (en) 1986-01-06 1986-12-24 Novel phenylnaphthyridines carrying functional groups in the 3-position the process for their preparation and drugs especially ulcer-inhibiting drugs in which they are present
AT86402949T ATE78478T1 (en) 1986-01-06 1986-12-29 PHENYLNAPHTHYRIDINE WITH A FUNCTIONAL GROUP IN POSITION 3, PROCESS FOR THEIR MANUFACTURE, PHARMACEUTICALS CONTAINING THIS PARTICULARLY AS ANTI-ULCUS.
DE8686402949T DE3686149T2 (en) 1986-01-06 1986-12-29 PHENYLNAPHTHYRIDINE WITH A FUNCTIONAL GROUP IN POSITION 3, METHOD FOR THE PRODUCTION THEREOF, THESE MEDICINAL PRODUCTS, PARTICULARLY AS AN ANTI-ULCUS.
EP86402949A EP0231709B1 (en) 1986-01-06 1986-12-29 Phenyl naphthyridines, with a functional group in position 3, process for their preparation, medicaments containing them, especially as anti-ulcers
ES86402949T ES2042506T3 (en) 1986-01-06 1986-12-29 NEW PHENYL-NAPHTIRIDINES FUNCTIONALIZED IN POSITION 3, THEIR PREPARATION PROCEDURE, DRUGS CONTAINING THEM, PARTICULARLY ANTI-ULCEROUS.
KR1019860011598A KR900004830B1 (en) 1986-01-06 1986-12-30 Process for the preparation of phenylnaphthyridines
PT84049A PT84049B (en) 1986-01-06 1987-01-02 PROCESS FOR THE PREPARATION OF NEW PHENYL-NAFTIRIDINES WITH FUNCTIONAL GROUP IN POSITION 3 AND MEDICINES THAT CONTAIN THEM
DK002787A DK2787A (en) 1986-01-06 1987-01-05 3-SUBSTITUTED 1- (SUBSTITUTED PHENYL) -1,2-DIHYDRO-2-OXO-1,8-NAPHTHYRIDINES AND THEIR PREPARATION AND USE
PH34691A PH24700A (en) 1986-01-06 1987-01-06 Novel phenylnaphthyridines containing a methyl substituent in the 3-position and composition containing the same
GR920402053T GR3005730T3 (en) 1986-01-06 1992-09-17

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8600103A FR2592650B1 (en) 1986-01-06 1986-01-06 NOVEL PHENYL-NAPHTYRIDINES FUNCTIONALIZED IN POSITION-3, THEIR PREPARATION PROCESS, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS.

Publications (2)

Publication Number Publication Date
FR2592650A1 true FR2592650A1 (en) 1987-07-10
FR2592650B1 FR2592650B1 (en) 1988-04-29

Family

ID=9330858

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8600103A Expired FR2592650B1 (en) 1986-01-06 1986-01-06 NOVEL PHENYL-NAPHTYRIDINES FUNCTIONALIZED IN POSITION-3, THEIR PREPARATION PROCESS, MEDICAMENTS CONTAINING THEM, IN PARTICULAR ANTI-ULCERS.

Country Status (1)

Country Link
FR (1) FR2592650B1 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128649A (en) * 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
EP0000490A1 (en) * 1977-07-18 1979-02-07 Merck & Co. Inc. Substituted naphthyridinones, processes for their preparations and therapeutical applications
US4215123A (en) * 1979-05-07 1980-07-29 American Home Products Corporation Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives
EP0018735A1 (en) * 1979-04-18 1980-11-12 American Home Products Corporation 1,8-Naphthyridine derivatives, their preparation, pharmaceutical compositions containing them

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4128649A (en) * 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters
EP0000490A1 (en) * 1977-07-18 1979-02-07 Merck & Co. Inc. Substituted naphthyridinones, processes for their preparations and therapeutical applications
EP0018735A1 (en) * 1979-04-18 1980-11-12 American Home Products Corporation 1,8-Naphthyridine derivatives, their preparation, pharmaceutical compositions containing them
US4215123A (en) * 1979-05-07 1980-07-29 American Home Products Corporation Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives

Also Published As

Publication number Publication date
FR2592650B1 (en) 1988-04-29

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