FR2556345B3 - Derive de pyrrolo(3,2,1-hi) indole, sa preparatio n et son application en therapeutique - Google Patents

Derive de pyrrolo(3,2,1-hi) indole, sa preparatio n et son application en therapeutique

Info

Publication number
FR2556345B3
FR2556345B3 FR8319850A FR8319850A FR2556345B3 FR 2556345 B3 FR2556345 B3 FR 2556345B3 FR 8319850 A FR8319850 A FR 8319850A FR 8319850 A FR8319850 A FR 8319850A FR 2556345 B3 FR2556345 B3 FR 2556345B3
Authority
FR
France
Prior art keywords
preparatio
pyrrolo
therapeutics
application
indole derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8319850A
Other languages
English (en)
Other versions
FR2556345A1 (fr
Inventor
Dennis Bigg
Claude Morel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR8319850A priority Critical patent/FR2556345B3/fr
Priority to KR1019840007549A priority patent/KR910005851B1/ko
Priority to EP84402477A priority patent/EP0145591B1/fr
Priority to AT84402477T priority patent/ATE35267T1/de
Priority to DE8484402477T priority patent/DE3472259D1/de
Priority to MX203667A priority patent/MX158671A/es
Priority to AU36496/84A priority patent/AU572237B2/en
Priority to FI844888A priority patent/FI76803C/fi
Priority to ZA849645A priority patent/ZA849645B/xx
Priority to NO844943A priority patent/NO162020C/no
Priority to DK590984A priority patent/DK164670C/da
Priority to HU844605A priority patent/HU190659B/hu
Priority to PT79658A priority patent/PT79658B/fr
Priority to JP59262636A priority patent/JPS60149588A/ja
Priority to CA000469792A priority patent/CA1238326A/fr
Priority to GR81235A priority patent/GR81235B/el
Priority to ES538475A priority patent/ES538475A0/es
Priority to NZ210516A priority patent/NZ210516A/en
Priority to IE3181/84A priority patent/IE57877B1/en
Priority to IL73786A priority patent/IL73786A/xx
Publication of FR2556345A1 publication Critical patent/FR2556345A1/fr
Priority to US06/770,079 priority patent/US4617313A/en
Application granted granted Critical
Publication of FR2556345B3 publication Critical patent/FR2556345B3/fr
Priority to CS914049A priority patent/CS404991A3/cs
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR8319850A 1983-12-12 1983-12-12 Derive de pyrrolo(3,2,1-hi) indole, sa preparatio n et son application en therapeutique Expired FR2556345B3 (fr)

Priority Applications (22)

Application Number Priority Date Filing Date Title
FR8319850A FR2556345B3 (fr) 1983-12-12 1983-12-12 Derive de pyrrolo(3,2,1-hi) indole, sa preparatio n et son application en therapeutique
KR1019840007549A KR910005851B1 (ko) 1983-12-12 1984-07-30 피롤로[3,2,1-hi]인돌유도체 및 약학적으로 허용되는 그의 산부가염을 제조하는 방법
EP84402477A EP0145591B1 (fr) 1983-12-12 1984-12-03 Dérivés de pyrrolo[3,2,1-hi]indole, leur préparation et leur application en thérapeutique
AT84402477T ATE35267T1 (de) 1983-12-12 1984-12-03 Pyrrolo(3,2,1-hi)indolderivate, ihre herstellung und ihre therapeutische anwendung.
DE8484402477T DE3472259D1 (en) 1983-12-12 1984-12-03 Pyrrolo(3,2,1-hi)indole derivatives, their preparation and their therapeutical use
MX203667A MX158671A (es) 1983-12-12 1984-12-10 Procedimiento para preparar derivados de pirrolo(3,2,1-hi)indol
HU844605A HU190659B (en) 1983-12-12 1984-12-11 Process for preparing pyrrolo/3,2,1-hi/indole derivatives and pharmaceutical compositions containing such compounds
ZA849645A ZA849645B (en) 1983-12-12 1984-12-11 Pyrrolo(3,2,1-hi)indole derivatives,their preparation and pharmaceutical compositions containing them
NO844943A NO162020C (no) 1983-12-12 1984-12-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolo-indol-derivater.
DK590984A DK164670C (da) 1983-12-12 1984-12-11 Pyrrolooe3,2,1-hiaaindol-derivater, fremgangsmaade til fremstilling deraf samt laegemidler indeholdende saadanne forbindelser
AU36496/84A AU572237B2 (en) 1983-12-12 1984-12-11 Imidazoline substituted pyrrolo (3,2,1-hi) indole derivatives
PT79658A PT79658B (fr) 1983-12-12 1984-12-11 Procede de preparation de derives de pyrrolo <3,2,1-hi> indole et de compositions pharmaceutiques les contenant
JP59262636A JPS60149588A (ja) 1983-12-12 1984-12-11 インドール誘導体およびその医薬への応用
CA000469792A CA1238326A (fr) 1983-12-12 1984-12-11 Derives de pyrrolo ¬3,2,1-hi|indole; preparation et compositions pharmaceutiques qui en renferment
GR81235A GR81235B (en) 1983-12-12 1984-12-11 Method for the preparation of pyrrolo (3,2,1-hi) indole derivatives
ES538475A ES538475A0 (es) 1983-12-12 1984-12-11 Un procedimiento para preparar derivados de pirrolo (3,2,1-hi)indol
NZ210516A NZ210516A (en) 1983-12-12 1984-12-11 Pyrrolo(3,2,1-hi)indoles and pharmaceutical compositions
IE3181/84A IE57877B1 (en) 1983-12-12 1984-12-11 Pyrrolo(3,2,1-hi)indole derivatives,their preparation and pharmaceutical compositions containing them
FI844888A FI76803C (fi) 1983-12-12 1984-12-11 Foerarande foer framstaellning av 2-(4,5-dihydro-1h-imidazol-2-yl-1,2,4,5-tetrahydropyrrolo/3,2,1-hi/ indoler vilka har aktivitet mot 2-adrenergiska receptorer.
IL73786A IL73786A (en) 1983-12-12 1984-12-12 2-(4,5-dihydro-1h-imidazol-2-yl)-1,2,4,5-tetrahydropyrrolo(3,2,1-hi)indoles,their preparation and pharmaceutical compositions containing them
US06/770,079 US4617313A (en) 1983-12-12 1985-08-28 Alpha2 -antagonistic 2-(4,5-dihydro-1H-imidazol-2-yl)-pyrrolo[3,2,1-hi]indoles
CS914049A CS404991A3 (en) 1983-12-12 1991-12-23 Pyrroloindole derivatives, process of their preparation and pharmaceutical compositions comprising said derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8319850A FR2556345B3 (fr) 1983-12-12 1983-12-12 Derive de pyrrolo(3,2,1-hi) indole, sa preparatio n et son application en therapeutique

Publications (2)

Publication Number Publication Date
FR2556345A1 FR2556345A1 (fr) 1985-06-14
FR2556345B3 true FR2556345B3 (fr) 1986-07-11

Family

ID=9295079

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8319850A Expired FR2556345B3 (fr) 1983-12-12 1983-12-12 Derive de pyrrolo(3,2,1-hi) indole, sa preparatio n et son application en therapeutique

Country Status (4)

Country Link
JP (1) JPS60149588A (fr)
CA (1) CA1238326A (fr)
FR (1) FR2556345B3 (fr)
ZA (1) ZA849645B (fr)

Also Published As

Publication number Publication date
FR2556345A1 (fr) 1985-06-14
ZA849645B (en) 1985-07-31
CA1238326A (fr) 1988-06-21
JPH0447673B2 (fr) 1992-08-04
JPS60149588A (ja) 1985-08-07

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Legal Events

Date Code Title Description
ST Notification of lapse