FR2546406A1 - Medical preparation for veterinary use, especially for lingual ulcers - Google Patents

Medical preparation for veterinary use, especially for lingual ulcers Download PDF

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Publication number
FR2546406A1
FR2546406A1 FR8402989A FR8402989A FR2546406A1 FR 2546406 A1 FR2546406 A1 FR 2546406A1 FR 8402989 A FR8402989 A FR 8402989A FR 8402989 A FR8402989 A FR 8402989A FR 2546406 A1 FR2546406 A1 FR 2546406A1
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FR
France
Prior art keywords
medical preparation
penicillin
lingual
ulcers
veterinary use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR8402989A
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French (fr)
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MICHAUX JEAN
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MICHAUX JEAN
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Publication date
Application filed by MICHAUX JEAN filed Critical MICHAUX JEAN
Publication of FR2546406A1 publication Critical patent/FR2546406A1/en
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a medical preparation for veterinary use, intended for exerting an action, in particular, on lingual ulcers of cattle. The preparation consists of a combination of beta -lactam, that is to say a substance (natural or synthetic) possessing antibiotic manifestations and classified in the penicillin family, and a phenicol, that is to say a substance (natural or synthetic) possessing antibiotic manifestations and classified in the chloramphenicol family. The preparation comprises chloramphenicol, lidocaine hydrochloride, procaine penicillin G and benzathine penicillin G, with addition of excipient QS.

Description

La présente invention est relative à une préparation médicale à usage vétérinaire, ayant pour but d'exercer une action, en particulier, sur les ulcères linguaux du bovin, appelés parfois chancres, champignons ou aphtes. The present invention relates to a medical preparation for veterinary use, the aim of which is to exert an action, in particular, on lingual bovine ulcers, sometimes called chancres, fungi or canker sores.

La préparation médicale suivant l'invention est caractérisée par la combinaison d'une B lactamine, c'est-àdire d'une substance (naturelle ou de synthèse) présentant des manifestations antibiotiques et se classant dans la famille des pénicillines et d'un phénicol, c'est-à-dire une substance (naturelle ou de synthèse) présentant des manifestations antibiotiques et se classant dans la famille des chloramphénicols. The medical preparation according to the invention is characterized by the combination of a B lactamine, that is to say a substance (natural or synthetic) exhibiting antibiotic manifestations and classifying in the family of penicillins and of a phenicol , that is to say a substance (natural or synthetic) presenting antibiotic manifestations and being classified in the family of chloramphenicols.

La combinaison de ces deux composants connus, phénicol et B lactamine, n'existe pas en temps que telle avec une spécificité d'action. L'effet obtenu sur le chancre lingual du bovin par cette combinaison n'est pas obtenu avec l'un ou l'autre de ces composants. The combination of these two known components, phenicol and B lactamine, does not exist as such with specificity of action. The effect obtained on the lingual canker of the bovine by this combination is not obtained with one or the other of these components.

Par ailleurs, aucune autre thérapie (chloramphénicol, sulfamide, teinture d'iode, etc...) ne montre une efficacité comparable à la préparation proposée suivant l'inntion. Les traitements traditionnels demandent un temps de guérison (partielle) de quatre à six jours, alors qu'un veau traité par la préparation suivant l'invention et suivant la dose indiquée est guéri après douze heures et peut se réalimenter, ce qui est primordial dans les élevages de veaux au pis. Furthermore, no other therapy (chloramphenicol, sulfonamide, tincture of iodine, etc.) shows an effectiveness comparable to the preparation proposed according to the invention. Traditional treatments require a (partial) healing time of four to six days, while a calf treated with the preparation according to the invention and according to the indicated dose is cured after twelve hours and can be fed again, which is essential in udder calf farms.

L'invention réside dans la combinaison des composants dans un but précis et spécifique, en ltoccwrence le chancre lingual des bovins, et à une concentration donnée. The invention lies in the combination of the components for a precise and specific purpose, in particular lingual chancre in cattle, and at a given concentration.

Suivant l'invention, cette préparation médicale comprend du chloramphénicol, du chlorhydrate de lidocaine, de la procaine pénicilline G et de la benzathine pénicilline G. According to the invention, this medical preparation comprises chloramphenicol, lidocaine hydrochloride, procaine penicillin G and benzathine penicillin G.

A cette composition on ajoute avantageusement de ltexci- pient Q.S. Advantageously, Q.S.

La préparation suivant l'invention se présente sous la formule suivante chloramphénicol + 250 mg chlorhydrate de lidocaine + 10 mg procaïne pénicilline 5 G -+ 150.000 unités benzathine pénicilline G ........ + 150.000 unités excipient Q.S............................... 1 ml
Cette préparation est dotée d'une activité exceptionnelle sur les ulcères linguaux du bovin. Une seule injection intramusculaire de 20 ml suffirait pour guérir le mal en trois jours.The preparation according to the invention is presented under the following formula chloramphenicol + 250 mg lidocaine hydrochloride + 10 mg procaine penicillin 5 G - + 150,000 units benzathine penicillin G ........ + 150,000 units excipient QS .... .......................... 1 ml
This preparation has an exceptional activity on lingual bovine ulcers. A single 20 ml intramuscular injection would be enough to cure the ailment in three days.

On peut citer comme emplois secondaires de cette préparation médicale pour les animaux la laryngite striduleuse et la cystite.  As secondary uses of this medical preparation for animals, we can cite stridulous laryngitis and cystitis.

Claims (4)

- REVENDICATIONS- CLAIMS 1. Préparation médicale à usage vétérinaire, caractérisée par la combinaison d'une B lactamine, c'est-àdire d'une substance (naturelle ou de synthèse) présentant des manifestations antibiotiques et se classant dans la famille des pénicillines et d'un phénicol, c'est-à-dire une substance (naturelle ou de synthèse) présentant des manifestations antibiotiques et se classant dans la famille des chloramphénicols. 1. Medical preparation for veterinary use, characterized by the combination of a B lactamine, that is to say of a substance (natural or synthetic) having antibiotic manifestations and classified in the family of penicillins and a phenicol , that is to say a substance (natural or synthetic) presenting antibiotic manifestations and being classified in the family of chloramphenicols. 2. Préparation médicale suivant la revendication 1, caractérisée en ce qu'elle comprend du chloramphénicol, du chlorhydrate de lidocaine, de la procaine pénicilline G et de la benzathine pénicilline G. 2. Medical preparation according to claim 1, characterized in that it comprises chloramphenicol, lidocaine hydrochloride, procaine penicillin G and benzathine penicillin G. 3. Préparation médicale suivant la revendication 2, caractérisée par une addition d'excipient Q.S. 3. Medical preparation according to claim 2, characterized by the addition of excipient Q.S. 4. Préparation médicale suivant la revendication 1, caractérisée en ce qu'elle présente la formule suivante : chloramphénicol ............................. 250 mg chlorhydrate de lidocaIne - 10 mg procaïne pénicilline G ........ 150.000 unités benzathine pénicilline G B.- 150.000 unités excipient Q.S.............................. ' 1 ml  4. Medical preparation according to claim 1, characterized in that it has the following formula: chloramphenicol ............................. 250 mg lidocaIne hydrochloride - 10 mg procaine penicillin G ........ 150,000 units benzathine penicillin G B. - 150,000 units excipient QS ................... .......... '1 ml
FR8402989A 1983-05-27 1984-02-23 Medical preparation for veterinary use, especially for lingual ulcers Withdrawn FR2546406A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE896866 1983-05-27

Publications (1)

Publication Number Publication Date
FR2546406A1 true FR2546406A1 (en) 1984-11-30

Family

ID=3862165

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8402989A Withdrawn FR2546406A1 (en) 1983-05-27 1984-02-23 Medical preparation for veterinary use, especially for lingual ulcers

Country Status (1)

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FR (1) FR2546406A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006064516A1 (en) * 2004-12-17 2006-06-22 Venus Remedies Limited Antibiotic combinations for providing total solution to the treatment of infections
US8921365B2 (en) 2007-07-23 2014-12-30 Biomet Deutschland Gmbh Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
UNLISTED DRUGS, vol. 22, no. 6, juin 1970, page 90, Chatham, New Jersey, US; *
UNLISTED DRUGS, vol. 23, no. 9, septembre 1971, page 132, Chatham, New Jersey, US; *
UNLISTED DRUGS, vol. 25, no. 12, décembre 1973, page 194, Chatham, New Jersey, US; *
UNLISTED DRUGS, vol. 27, no. 11, novembre 1975, page 173, Chatham, New Jersey, US; *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006064516A1 (en) * 2004-12-17 2006-06-22 Venus Remedies Limited Antibiotic combinations for providing total solution to the treatment of infections
JP2008524204A (en) * 2004-12-17 2008-07-10 ヴィーナス・レメディーズ・リミテッド Combination of antibiotics to give a complete solution to the treatment of infection
US8178501B2 (en) 2004-12-17 2012-05-15 Venus Remedies Limited Antibiotic combinations for providing total solution to the treatment of infections
US8921365B2 (en) 2007-07-23 2014-12-30 Biomet Deutschland Gmbh Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
US9968710B2 (en) 2007-07-23 2018-05-15 Biomet Deutschland Gmbh Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition

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