FR2545721B1 - Osmotic device for the release of materials in an environment of use - Google Patents

Osmotic device for the release of materials in an environment of use


Publication number
FR2545721B1 FR8405362A FR8405362A FR2545721B1 FR 2545721 B1 FR2545721 B1 FR 2545721B1 FR 8405362 A FR8405362 A FR 8405362A FR 8405362 A FR8405362 A FR 8405362A FR 2545721 B1 FR2545721 B1 FR 2545721B1
Prior art keywords
osmotic device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Application number
Other languages
French (fr)
Other versions
FR2545721A1 (en
Patrick S L Wong
Brian Barclay
Joseph C Deters
Felix Theeuwes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US49376083A priority Critical
Application filed by Alza Corp filed Critical Alza Corp
Publication of FR2545721A1 publication Critical patent/FR2545721A1/en
Application granted granted Critical
Publication of FR2545721B1 publication Critical patent/FR2545721B1/en
First worldwide family litigation filed litigation Critical "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application status is Expired legal-status Critical



    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
FR8405362A 1983-05-11 1984-04-05 Osmotic device for the release of materials in an environment of use Expired FR2545721B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US49376083A true 1983-05-11 1983-05-11

Publications (2)

Publication Number Publication Date
FR2545721A1 FR2545721A1 (en) 1984-11-16
FR2545721B1 true FR2545721B1 (en) 1987-11-06



Family Applications (1)

Application Number Title Priority Date Filing Date
FR8405362A Expired FR2545721B1 (en) 1983-05-11 1984-04-05 Osmotic device for the release of materials in an environment of use

Country Status (20)

Country Link
JP (1) JPH0575725B2 (en)
AT (1) AT397180B (en)
AU (1) AU566110B2 (en)
BE (1) BE898819A (en)
CA (1) CA1222950A (en)
CH (1) CH669329A5 (en)
DE (1) DE3417113C2 (en)
DK (1) DK163910C (en)
ES (1) ES532018A0 (en)
FR (1) FR2545721B1 (en)
GB (1) GB2140687B (en)
IE (1) IE56515B1 (en)
IL (1) IL71727A (en)
IT (1) IT1178911B (en)
MX (1) MX163518B (en)
NL (1) NL192250C (en)
NO (1) NO170834C (en)
NZ (1) NZ206600A (en)
SE (1) SE455918B (en)
ZA (1) ZA8402422B (en)

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JPH075457B2 (en) * 1983-08-16 1995-01-25 ザ ウエルカム フアウンデ−シヨン リミテツド Pharmaceutical compositions which allow release of the active ingredient by controlled manner
US4600773A (en) * 1983-12-01 1986-07-15 Eli Lilly And Company Crystalline cephalexin hydrochloride monohydrate
US4624847A (en) * 1985-04-22 1986-11-25 Alza Corporation Drug delivery device for programmed delivery of beneficial drug
US4704118A (en) * 1985-08-16 1987-11-03 Alza Corporation Ruminant dispensing device with thermo-activated memory
US4963141A (en) * 1985-08-16 1990-10-16 Alza Corporation Dispensing system for administering beneficial agent formulation to ruminants
ES8800043A1 (en) * 1985-08-16 1987-10-16 Alza Corp A distributor device for discharging a beneficial agent formulation to an environment of use
US4723957A (en) * 1986-02-07 1988-02-09 Alza Corp. System for delivering drug with enhanced bioacceptability
US4716496A (en) * 1986-05-09 1987-12-29 Eaton Corporation Panel-mounted control station housing
US4814181A (en) * 1987-09-03 1989-03-21 Alza Corporation Dosage form comprising fast agent delivery followed by slow agent delivery
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
DE3871343D1 (en) * 1987-11-25 1992-06-25 American Cyanamid Co System for delayed (controlled) release of substituted dihydropyridine calcium antagonists.
US4837111A (en) * 1988-03-21 1989-06-06 Alza Corporation Dosage form for dispensing drug for human therapy
US4855141A (en) * 1988-03-25 1989-08-08 Alza Corporation Device comprising means for protecting and dispensing fluid sensitive medicament
US4859470A (en) * 1988-06-02 1989-08-22 Alza Corporation Dosage form for delivering diltiazem
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
IL91398D0 (en) * 1988-08-30 1990-04-29 Pfizer Use of asymmetric membranes in delivery devices
GR1000270B (en) * 1988-09-30 1992-05-12 Alza Corp Dose for cardiovascular troubles therapy
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
EP0408496A3 (en) * 1989-07-12 1992-07-01 Ciba-Geigy Ag Solid dosage form for pharmaceutical substances
US4992277A (en) * 1989-08-25 1991-02-12 Schering Corporation Immediate release diltiazem formulation
US5000962A (en) * 1989-08-25 1991-03-19 Schering Corporation Long acting diltiazem formulation
US5067960A (en) * 1989-12-06 1991-11-26 Medtronic, Inc. Muscle fitness detection by colorimetry
US5190763A (en) * 1990-05-07 1993-03-02 Alza Corporation Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
US5081161A (en) * 1990-06-15 1992-01-14 E. I. Du Pont De Nemours And Company Process for making shaped articles of a thermoplastic resin having a microcellular structure
NZ238867A (en) * 1990-07-12 1993-08-26 Alza Corp Dosage form for delayed release comprising pharmaceutically active substance and a drug-release hindering means and a second composition which imbibes fluid, expands, and ejects the active substance from the device
DE69107461T2 (en) * 1990-08-07 1995-06-22 Pfizer Using interfacial polymerized membranes in delivery devices.
US5166145A (en) * 1990-09-10 1992-11-24 Alza Corporation Antiemetic therapy
WO1992005775A1 (en) * 1990-09-28 1992-04-16 Pfizer Inc. Dispensing device containing a hydrophobic medium
US5208037A (en) * 1991-04-22 1993-05-04 Alza Corporation Dosage forms comprising polymers comprising different molecular weights
AT200221T (en) * 1993-02-23 2001-04-15 Wolfgang Dr Werner The use of a calcium medication, is a drug for treatment of hypocalcemia in dairy cows suffering
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US6287598B1 (en) * 1993-05-28 2001-09-11 Alza Corporation Method for providing sustained antiepileptic therapy
HU213407B (en) * 1993-12-09 1997-06-30 Egyt Gyogyszervegyeszeti Gyar Process for producing tablet with diffusive-osmotic release
US5460826A (en) * 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
US5948787A (en) * 1997-02-28 1999-09-07 Alza Corporation Compositions containing opiate analgesics
DE19962924A1 (en) 1999-12-24 2001-07-05 Bayer Ag Substituted oxazolidinones and their use
HU230686B1 (en) * 2000-10-30 2017-08-28 Euro-Celtique S A Controlled release hydrocodone compositions
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
DE10129725A1 (en) 2001-06-20 2003-01-02 Bayer Ag Combination therapy of substituted oxazolidinones
DE10300111A1 (en) 2003-01-07 2004-07-15 Bayer Healthcare Ag Process for the preparation of 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4-morpholinyl) phenyl] -1,3-oxazolidin-5-yl} methyl ) -2-thiophenecarboxamide
US10226428B2 (en) 2003-09-19 2019-03-12 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
US10213387B2 (en) 2003-09-19 2019-02-26 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
PL1663175T3 (en) 2003-09-19 2012-09-28 Sun Pharma Advanced Res Company Limited Oral drug delivery system
DE10355461A1 (en) 2003-11-27 2005-06-23 Bayer Healthcare Ag Solid, high bioavailabilty oral formulations of N-substituted 5-chloro-2-thiophene-carboxamide derivative in hydrophilized form, useful for combating thrombo-embolic diseases
DE102004062475A1 (en) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Solid, orally administrable, modified release pharmaceutical dosage forms
EP1685841A1 (en) 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
DE102005031577A1 (en) 2005-07-06 2007-01-11 Bayer Healthcare Ag Pharmaceutical dosage forms containing a combination of nifedipine and / or nisoldipine and an angiotensin II antagonist
DE102005045518A1 (en) 2005-09-23 2007-03-29 Bayer Healthcare Ag New 5-thienylaminocarbonylmethyl-oxazolidin-2-one derivatives, useful for treating and preventing thromboembolic disease, are selective inhibitors of coagulation factor Xa
DE102005047561A1 (en) 2005-10-04 2007-04-05 Bayer Healthcare Ag Drug delivery system, useful to treat and/or prevent e.g. thromboembolic disease, comprises 5-chloro-N-(((5S)-2-oxo-3-(4-(3-oxo-4-morpholinyl)-phenyl)-1,3-oxazolidine-5-yl)-methyl)-2-thiophene carboxamide with fast release active substance
PL1934208T3 (en) 2005-10-04 2011-09-30 Bayer Ip Gmbh Novel polymorphous form of 5-chloro-n-({ (5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide
DE102008059206A1 (en) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical dosage form containing nifedipine or nisoldipine and an angiotensin II antagonist and / or a diuretic
JP2012528799A (en) * 2009-06-02 2012-11-15 ダウ グローバル テクノロジーズ エルエルシー Sustained release formulation
CA2872542A1 (en) 2012-05-07 2013-11-14 Bayer Pharma Aktiengesellschaft Process for manufacturing a pharmaceutical dosage form comprising nifedipine and candesartan cilexetil
UY34856A (en) 2012-07-03 2013-12-31 Bayer Pharma AG Pharmaceutical presentations containing 5-chloro-N - ({(5S) -2-oxo-3- [4- (3-oxo-4- morpholinyl) -phenyl] -1,3-oxazolidin-5-yl} -methyl) -2-thiophenecarboxamide
JP5941117B2 (en) * 2014-10-17 2016-06-29 ダウ グローバル テクノロジーズ エルエルシー Sustained release formulation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL38538A (en) * 1971-01-13 1974-09-10 Alza Corp Osmotic dispenser
US3977404A (en) * 1975-09-08 1976-08-31 Alza Corporation Osmotic device having microporous reservoir
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4160452A (en) * 1977-04-07 1979-07-10 Alza Corporation Osmotic system having laminated wall comprising semipermeable lamina and microporous lamina
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4265874A (en) * 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device

Also Published As

Publication number Publication date
ES532018D0 (en)
DE3417113C2 (en) 1989-02-02
IL71727A (en) 1989-01-31
MX163518B (en) 1992-05-25
NZ206600A (en) 1987-01-23
NL192250C (en) 1997-04-03
DK163910C (en) 1992-09-14
ATA88084A (en) 1993-07-15
DK99784D0 (en) 1984-02-24
CA1222950A (en) 1987-06-16
SE8402512D0 (en) 1984-05-09
NO170834B (en) 1992-09-07
DE3417113A1 (en) 1984-11-15
NO170834C (en) 1992-12-16
JPH0575725B2 (en) 1993-10-21
IE56515B1 (en) 1991-08-28
AU2251183A (en) 1984-11-15
IE840010L (en) 1984-11-11
NL8401470A (en) 1984-12-03
NL192250B (en) 1996-12-02
BE898819A (en) 1984-05-30
GB2140687A (en) 1984-12-05
ES532018A0 (en) 1985-03-01
JPS6041609A (en) 1985-03-05
AT397180B (en) 1994-02-25
CH669329A5 (en) 1989-03-15
BE898819A1 (en)
AU566110B2 (en) 1987-10-08
DK163910B (en) 1992-04-21
SE455918B (en) 1988-08-22
FR2545721A1 (en) 1984-11-16
ZA8402422B (en) 1984-11-28
GB8334189D0 (en) 1984-02-01
IL71727D0 (en) 1984-09-30
IT1178911B (en) 1987-09-16
CA1222950A1 (en)
IT8467283D0 (en) 1984-03-23
NO840248L (en) 1984-11-12
GB2140687B (en) 1987-03-18
ES8503503A1 (en) 1985-03-01
DK99784A (en) 1984-11-12
SE8402512L (en) 1984-11-12

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