FR2525597B1 - Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant - Google Patents

Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant

Info

Publication number
FR2525597B1
FR2525597B1 FR8206813A FR8206813A FR2525597B1 FR 2525597 B1 FR2525597 B1 FR 2525597B1 FR 8206813 A FR8206813 A FR 8206813A FR 8206813 A FR8206813 A FR 8206813A FR 2525597 B1 FR2525597 B1 FR 2525597B1
Authority
FR
France
Prior art keywords
chlorine
fluorine
substituted
alkyl
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8206813A
Other languages
English (en)
French (fr)
Other versions
FR2525597A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Servier de Medecine Translationnelle SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Priority to FR8206813A priority Critical patent/FR2525597B1/fr
Priority to US06/486,013 priority patent/US4514399A/en
Priority to EP83400755A priority patent/EP0092479B1/fr
Priority to AT83400755T priority patent/ATE17724T1/de
Priority to DE8383400755T priority patent/DE3361972D1/de
Priority to NZ203954A priority patent/NZ203954A/en
Priority to CA000426310A priority patent/CA1203803A/fr
Priority to PT76575A priority patent/PT76575B/pt
Priority to JP58069890A priority patent/JPS58189168A/ja
Priority to AU13814/83A priority patent/AU555980B2/en
Priority to OA57972A priority patent/OA07400A/xx
Priority to ZA832778A priority patent/ZA832778B/xx
Priority to ES521721A priority patent/ES521721A0/es
Publication of FR2525597A1 publication Critical patent/FR2525597A1/fr
Application granted granted Critical
Publication of FR2525597B1 publication Critical patent/FR2525597B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40—Nitrogen atoms
    • C07D251/54—Three nitrogen atoms
    • C07D251/70—Other substituted melamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
  • Detergent Compositions (AREA)
FR8206813A 1982-04-21 1982-04-21 Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant Expired FR2525597B1 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
FR8206813A FR2525597B1 (fr) 1982-04-21 1982-04-21 Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
EP83400755A EP0092479B1 (fr) 1982-04-21 1983-04-18 Polymethylène diamines, n,n'-substituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
AT83400755T ATE17724T1 (de) 1982-04-21 1983-04-18 Polymethylen-diamine n,n'-substituiert, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
DE8383400755T DE3361972D1 (en) 1982-04-21 1983-04-18 N,n'-substituted polymethylene diamines, processes for their preparation and pharmaceutical compositions containing them
US06/486,013 US4514399A (en) 1982-04-21 1983-04-18 N-N'substituted polymethylene diamines
CA000426310A CA1203803A (fr) 1982-04-21 1983-04-20 Procede de preparation de polymethylene-diamines n,n'- substitues
NZ203954A NZ203954A (en) 1982-04-21 1983-04-20 N,n'-disubstituted polymethylene diamines
PT76575A PT76575B (fr) 1982-04-21 1983-04-20 Procede de preparation de polymethylene-diamines n,n'-substituees
JP58069890A JPS58189168A (ja) 1982-04-21 1983-04-20 トリアジン誘導体
AU13814/83A AU555980B2 (en) 1982-04-21 1983-04-20 Tri substituted melamines
OA57972A OA07400A (fr) 1982-04-21 1983-04-20 Polyméthylène diamiques, N,N'-subtituées, leurs procédés de préparation et les compositions pharmaceutiques les renfermant.
ZA832778A ZA832778B (en) 1982-04-21 1983-04-20 N,n'-substituted polymethylene diamines,processes for their preparation and pharmaceutical compositions containing them
ES521721A ES521721A0 (es) 1982-04-21 1983-04-21 Procedimiento de preparacion de las polimetileno diaminas n,n'-sustituidas.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8206813A FR2525597B1 (fr) 1982-04-21 1982-04-21 Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
FR2525597A1 FR2525597A1 (fr) 1983-10-28
FR2525597B1 true FR2525597B1 (fr) 1985-06-07

Family

ID=9273200

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8206813A Expired FR2525597B1 (fr) 1982-04-21 1982-04-21 Polymethylene diamines n,n'-substituees, leurs procedes de preparation et les compositions pharmaceutiques les renfermant

Country Status (13)

Country Link
US (1) US4514399A (enExample)
EP (1) EP0092479B1 (enExample)
JP (1) JPS58189168A (enExample)
AT (1) ATE17724T1 (enExample)
AU (1) AU555980B2 (enExample)
CA (1) CA1203803A (enExample)
DE (1) DE3361972D1 (enExample)
ES (1) ES521721A0 (enExample)
FR (1) FR2525597B1 (enExample)
NZ (1) NZ203954A (enExample)
OA (1) OA07400A (enExample)
PT (1) PT76575B (enExample)
ZA (1) ZA832778B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0145660B1 (de) * 1983-12-02 1990-04-18 Ciba-Geigy Ag Schädlingsbekämpfungsmittel
DE3401675A1 (de) * 1984-01-19 1985-07-25 Bayer Ag, 5090 Leverkusen Neue polyamine und ein verfahren zu ihrer herstellung
GB8421555D0 (en) * 1984-08-24 1984-09-26 Ici Plc Water-soluble dye
DE3438694A1 (de) * 1984-10-23 1986-04-24 Basf Ag, 6700 Ludwigshafen Neue amidoalkylmelamine und aminoalkylmelamine und verfahren zu ihrer herstellung
JPH01121755U (enExample) * 1988-02-15 1989-08-17
FR2667243B1 (fr) * 1990-09-27 1994-11-04 Adir Utilisation de s derives de la triazine et de la pyrimidine pour l'obtention de medicaments reversant la resistance aux agents anticancereux et antimalariques.
FR2673627B1 (fr) * 1991-03-07 1993-05-07 Adir Triazines et pyrimidines trisubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
JP2002509140A (ja) * 1998-01-13 2002-03-26 アナディーズ・ファーマスーティカルズ，インコーポレイテッド トリアジン抗ウイルス化合物
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US6225378B1 (en) * 1999-07-01 2001-05-01 Industrial Technology Research Institute Triazine hardener and epoxy composition containing the same
US6943161B2 (en) * 1999-12-28 2005-09-13 Pharmacopela Drug Discovery, Inc. Pyrimidine and triazine kinase inhibitors
CA3087881A1 (en) 2017-01-17 2018-07-26 Michael David FORREST Therapeutic inhibitors of the reverse mode of atp synthase
CA3099077A1 (en) 2017-07-13 2019-01-17 Michael David FORREST Therapeutic modulators of the reverse mode of atp synthase

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE651967A (enExample) * 1963-01-11
FR1451232A (fr) * 1963-11-19 1966-01-07 Science Union Et Compagnie Nouveaux dérivés de la pyrimidine et leur procédé de préparation
CH441351A (de) * 1964-06-02 1967-08-15 Geigy Ag J R Verfahren zur Herstellung N2-substituierter 2,4,6-Triamino-1,3,5-triazine
DE1620528A1 (de) * 1965-12-31 1970-06-11 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen basisch substituierten s-Triazinen
GB1256513A (enExample) * 1968-10-02 1971-12-08
NL7103449A (enExample) * 1971-03-15 1972-09-19
US4261892A (en) * 1978-04-12 1981-04-14 American Cyanamid Company 2,4,6-Tris-(substituted-amino)-s-triazines

Also Published As

Publication number Publication date
ZA832778B (en) 1983-12-28
OA07400A (fr) 1984-11-30
ATE17724T1 (de) 1986-02-15
PT76575B (fr) 1985-12-10
EP0092479A1 (fr) 1983-10-26
JPS6240357B2 (enExample) 1987-08-27
CA1203803A (fr) 1986-04-29
ES8405776A1 (es) 1984-06-16
NZ203954A (en) 1986-01-24
DE3361972D1 (en) 1986-03-13
AU555980B2 (en) 1986-10-16
ES521721A0 (es) 1984-06-16
US4514399A (en) 1985-04-30
FR2525597A1 (fr) 1983-10-28
EP0092479B1 (fr) 1986-01-29
JPS58189168A (ja) 1983-11-04
AU1381483A (en) 1983-10-27
PT76575A (fr) 1983-05-01

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Legal Events

Date Code Title Description
ST Notification of lapse