FR2524261A1 - FENARIMOL FUNGICIDE POWDER COMPOSITION - Google Patents

Abstract

The invention relates to solid, stable fungicidal compositions based on fenarimol in the form of a mixture with other pulverulent active substances. The compositions contain not more than 1% of fenarimol in the form of granules containing more than 1% by weight of active substance as well as a preferably water-soluble filler. The compositions are chemically stable and readily dispersible in water.

Description

 The present invention relates to a new fungus, stable, dispersible cornsition @ in the @@ u, based on fenarimol, its preparation and its application to the protection of plants against fungal diseases.

 The α (2-chloro-phenyl) α -4-chloro-phenyl) pyrimielne-5 methanol or fenarimol is a known fungal active ingredient having interesting fungal properties for the protection of plants, in particular the vine, arboriculture and cereals, against diseases such as powdery mildew. This active ingredient is generally formulated either as an aqueous concentrated suspension, or as an emulsifiable concentrate, or as a wettable powder.

 For crops such as the vine or arboriculture, it is advantageous to be able to combine the anti-powdery mildew treatment with other treatments, in particular anti-mildew. Some ready-to-use combinations, in pouore, containing fenarimol have been proposed but the chemical stability or fenarimol is not satisfactory there.

Indeed, fenarimol being active in very low doses compared to the other active materials and in particular the anti-mildew, it is found in very small proportion, generally less than 1 W, in the final mixture. When this mixture is a mixture of wetted powders, it is noted that the fenarimol degrades rapidly at storage, which makes it difficult to present a commercially acceptable product.

 The oemanoeresse has now found a way to alleviate this problem and to provide stable, powdered, containing or fenarimol powder compositions in mixture with other active ingredients, in particular fungicides.

 The present invention relates in particular to a fungicidal powder composition of several phytosanitary active ingredients, one of which is fenariol, at a rate not more than 1g in poios, the other active ingredients being in @e form powder nouilla @@ e or oe po @@@ e soluble, characterized er that the fenarimal is in the form oe granulated at tocispersatle dispersed in the po @ re and intrinsically containing more oe 1 S in poen of fenarimel and.

a filler, this water-soluble preference.

 This self-dispersible granule, this apparent density comprised between approx 0.3 and 0.6, has a particle size generally comprised between approximately 150 and 2000 and preferably between 300 and 1500 microns. Particles smaller than 150 microns in size are not desirable because then fenarimol is no longer sufficiently stable. On the other hand, granules of average size greater than 2000 microns are too large compared to the grains of being, which results in a separation between the granule and the powder and therefore a loss of homogeneity of the entire composition. .

 The fenarimol content of this granule must be greater than 1 m in pria. The upper limit is not critical but the content is generally between approximately 1 and 30%, and preferably between 5 and 20 5.

 The remainder or granule is essentially composed of a joist filler and possibly adjuvants ten sioactits giving the granule properties of self-dispersibility in water. These granules comprise more than 50% in poios this filler and can be essentially that those cistinct types depending on whether the filler retained is soluble or not in water. When the filler is water-soluble, it can be mineral and preferably organic. Excellent results have been obtained with urea. In the case of an insoluble filler, it is preferably mineral, such as, for example, kaolin or tentonite. It is then accompanied by surface-active agents, at a rate of 2 to 15% by weight or granulated, surface-active aojuvants, more than half of which is constituted by a dispersing agent, essentially a'icaioue, such as o @ '. an alkaline or alkaline earth nap @ talene sulfonate condensed to the formal cu an alkaline or alkaline earth liqrosulfonate, the remainder being constituted by these nonionic or anionic wetting agents such as an alkali or alkaline alkaline naphthalene sulfonate.

 Furthermore, although this is not essential, other adjuvants such as these defoamers can be added.

 The granulate according to the invention can be prepared by mixing the necessary ingredients and then granulation according to several techniques known per se (drageoir, fluioe bed, atomizer, extrusion, etc.). It generally ends with crushing followed by sieving to the particle size chosen within the limits mentioned above.

 To obtain the compositions according to the invention, the granule prepared above is mixed with one or more active materials, in particular fungicides, in wettable or soluble powder. As fungicidal active substances which can be used, mention may in particular be made of phosetyl Al, phos-etyl Ca, sodium ethylphosphite, mono and disodium phosphites, contact fungicides such as or manet, lc zinèbe, mancozeb, captan , captafo.l or folpel.

 Wettable powders (or spraying powders) are usually prepared so that they contain 20 to 95 ç in pcics of active material, and they usually contain, in addition to the solid support, this 0 to 5% o'an agent wetting, from 3 to 1C, of a thickening agent, and, when necessary, from 0 to 10% of one or more stabilizers and / or other additives, such as penetration agents, adhesives, or anti-caking agents; dyes, etc ...

 As an example, here are various composition oe.

wettable powders - active ingredient 50% - lignosulfonate ce calcium (deflocculant) 5 5 - isopropylnaphthalene sul @ onate (agent
anionic wetting) 1% - anti-clumping silica - kaolin (filler)
Another example of an 80% wettable powder is known below:
. active ingredient ................................... 80%
. sodium alkylnaphthalene sulfonate .............. 2%
lignosulfonate oe socium .......................

antimettant silique; w
. kaolin ........................................... 13%
Another example of a wettable powder is given below:
. active ingredient .................................. 50%
. sodium alkylnaphthalene sulfonate ............. 2%
. methyl cellulose ce low viscosity 2 5.

. diatomaceous earth .............................. 46%
Another example of a wettable powder is given below:
. active ingredient ................................... 90%
. sodium dioctylsulfosuccinate .................. 0.2%
. synthetic silica ............................... 9.8%
Another 70% spray powder composition uses the following constituents - active ingredient 700 e - sodium dibutylnaphthylsulfonate 50 g - produces this condensation in proportions
3/2/1 of naphthalene sulphonous acid,
o the phenolsulfonic acid and
formaloéhyce 30 g - ka-olin 100 o - champagne chalk 120 g
Another composition: this powder C spray at 40% uses the following constituents - active ingredient 400 g - lignosulfonate this sodium 50 g - ditutylnaphthalene sodium sulfonate 10 c - silica 540 g
Another 25% spray powder composition uses the following constituents - active ingredient 5C c - calcium lignosulfonate 45 g - equiponderal mixture of Champagne chalk
and hyaroxyethylcellulose 18 g - sodium cibutylnaphthalene sulfonate 15 g - silica 195 g - Champagne chalk 195 o - kaolin 281 o
Another 25% spray powder composition uses the following constituents - active ingredient 250 g - isooctylphenoxy-polyoxyethylene-ethanol 25 9 - equiponaeral mixture this chalk oe
Champagne and hydroxyethylcellulose 17 r - sodium aluminosilicate 543 g - kieselguhr 165 c
Another 10 L spray powder composition uses the following constituents - active ingredient 100 5 - mixture of sodium salts and sulfates
of saturated fatty acids 3C g - conquering acioe naphta
lene sulfonicue and ce formaldehyce 50 Q - kaolin 820 g
In order to obtain these spraying powders or wettable powders, the active ingredients are intimately mixed in the appropriate mixers with the accidental substances and ground with these mills or other suitable grinders. This gives spraying powders whose wettability and suspension are advantageous; they can be suspended with this water at any cesirge concentration and this suspension can be used very advantageously in particular for the application to Touilles these plants.

 Acute isopersions and enulsions, for example of the compositions obtained by ciluting with a water aid a wettable powder according to the invention, are included, except the general caore of the compositions which can be used in the present invention.

 All these dispersions or emulsions, which are sharp or boiled, are applicable to the cultures to be treated by any suitable means, mainly by spraying, at doses which are generally of the order of 10 to 1200 liters of porridge per hectare.

 The concentrated powder compositions thus obtained exhibit very good physical and chitric stability on storage. In particular, the chemical stability of fenarimol is remarkable despite its low content and satisfies the standardized conoitions required for this type of composition.

 In addition and as a corollary, these compositions have excellent water dispersibility properties allowing preparation and use. easy these spray porridges.

 The following examples are given to illustrate the preparation of the compositions according to the invention as well as these compositions and their characteristics.

Example 1 to 3
This technical narimol and 90% urea in pearls are mixed in a blender in a mixer. The mixture is then ground in a pin mill. We keep unr.

powder which is moistened with about 8 W in dots of water.

The humorous thumb is extruded in a perforated reuleau extruder. A granule is obtained which is dried, then crushed and sieved, so as not to respectively park the granules with a dimension between
- 150 and 600 microns (Example 1)
- 300 and 1500 microns (Example 2)
- 300 and 2000 microns (Example 3).

 A microwavable wettable powder is prepared separately containing by weight 52% of phosethyl Al, 26% of felpel, 0.5% of a nonionic wetting agent ethylene oxide concentrate on a phenol, 2% of a anionic dispersant sodium alkyl naphthalene sulfonate, 3 W of a nonionic dispersant, ethylene oxide condensate (8-10 moles on a tristyrylphenol), the remainder consisting of or kaolin.

 To three samples of this powder, 4% by weight of granule according to one of examples 1 to 3 are respectively added to 10 W of fenarimol in a ribbon mixer, ie 0.4% of fenarimol in each of the mixtures porridge per hectare.

Samples of these mixtures corresponding to Examples 1 to 3 are subjected to the following tests:
1) Chemical stability test:
A sample is placed in an oven at 50 ° C. for 1 month, which subjects the sample to aging equivalent to aging — for at least one year at 20 ° C. Under these conditions, it is then observed, by assay, that the rate this degradation of fenarimol is respectively
- Example 1: around 15 W
- Examples 2 and 3: less than 5 W.

Under the same conditions, in a comparable mixture in which the fenarimol is in the conventional form of a pouare (particle size of the orore of 1 micron), the degradation rate of the fenarimol is greater than 50%
2) Suspensibility test
The CIPAC MT15.1 method is used Note 4, p.

861 to 865 described in CIPAC Hanbook, Vol. 1, 197, edited by G.R. RAW. Collaborative International Pesticides Analytical Council Limitec.

 To this method, the samples corresponding to Examples 1 to 3 of the final mixture are subjected, maintained respectively at 20 and 50 C for 1 month.

The results are recorded in the following table and expressed in percent suspension power as defined by the above standard.
Example 1 month at 20C 1 month at 500C
1 89 8t
2 79 56
3 76 55
It can be seen that the samples all have a higher and often much higher than 50% suspension power and are therefore of excellent quality.

Example 4
In a pin mill, the mixture having the following composition by weight fenarimol 10% alkyl sodium naphthalene sulfonate is ground
(wetting) 2% condensed sodium naphthalene sulfonate
formalin (dispersant) 8% kaolin 80%
The ground mixture is then, after adding 10 by weight of water, granule in the bezel then dried, crushed and sieved so as to obtain a granule of size between 0.16 and 0.40 mm. The granule obtained is then mixed with the same wettable powder based on phosetyl Al and this folpel and without the same conditions as in Examples 1 to 3. The final formula contains 0.4% in polos or fenarimol.

A sample of this mixture is subjected to the tests described in Examples 1 to 3. Under these conditions, it is observed that
a) - the degradation rate or fenarimol is less than 5%,
then yes in the analogous mixture oe reference, this rate is greater than 50%;
b) the power of suspension is 60% after maintenance for 1 month at 50 C.

Claims (12)

 1) A powdery, stable and cispersatle composition in water, of several phytosanitary active ingredients, one of which is fenarimol in a proportion of at most 1% by weight, the other active ingredients being in the form of wettable or soluble powders, characterized in that the fenarimol is in the form of a self-dispersible granule, dispersed in the pouore and intrinsically containing more than 1% by weight of fenarimol and a filler.  2) Composition according to claim 1, characterized in that the weight content of the fenarimol granule is between 1 and 30 S.  3) Composition according to claim 2, characterized in that the weight content of the fenarimol granule is between 5 and 20 S.  4) Composition according to one of claims 1 to 3, characterized in that the granule has a particle size of 150 to 2000 microns.  S) Composition according to claim 4, characterized in that the granule has a dimension of this particles from 300 to 1500 microns  6) Composition according to one of these revencicaticns 1 to 5, characterized in that the granule contains a hyorosolubic filler.  7) Composition according to claim (, characterized in that the water-soluble filler is urea.  8) Composition according to one of these claims 1 to 5, characterized in that the granule contains a water-insoluble charoe and 2 to 15% surfactant adjuvants containing more than 5% in peaks or at least one dispersant.  9) Composition according to one of these claims 1 to 8, characterized in that the fenarimol is er. mix with an active fungicide dobby.  10) Composition according to claim%, characterized in that the fenarimol is in admixture with at least phosethyl Al.  11) Composition according to claim 5, characterized in that the renarimol is mixed with at least folpel.  12) Conposition according to revencication c, characterized in that fenarimol with phosetyl Al and folpel.  13) Procéoé this manufacture of a composition according to one of claims 1 to 12, characterized in that cn is prepared separately a granule oe fenarimol and the other active ingredient (s) in wettable or soluble powders and which is then mixed the oranule with the powders.  14) Process according to claim 13, characterized in that the fenarimol granule is obtained by extrusion of a mixture of technical fenarimol and urea, then crushing and sieving.  15) A method of protecting these plants against fungal diseases, characterized in that a composition according to one of claims 1 to 14 is applied, dispersing water.