FR2518544B1 - - Google Patents

Info

Publication number
FR2518544B1
FR2518544B1 FR8123909A FR8123909A FR2518544B1 FR 2518544 B1 FR2518544 B1 FR 2518544B1 FR 8123909 A FR8123909 A FR 8123909A FR 8123909 A FR8123909 A FR 8123909A FR 2518544 B1 FR2518544 B1 FR 2518544B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8123909A
Other languages
French (fr)
Other versions
FR2518544A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LIPHA SAS filed Critical LIPHA SAS
Priority to FR8123909A priority Critical patent/FR2518544A1/en
Publication of FR2518544A1 publication Critical patent/FR2518544A1/en
Application granted granted Critical
Publication of FR2518544B1 publication Critical patent/FR2518544B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10Oxygen atoms
    • C07D309/12Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8123909A 1981-12-22 1981-12-22 3-Hydroxy-ethyl 1,3,4,5-tetra:hydro 1,3-benzodiazepine-2-thione(s) - and related cpds. are antidepressants, intermediate 2-amino-phenyl-ethyl-amino-ethanol derivs. are also new Granted FR2518544A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8123909A FR2518544A1 (en) 1981-12-22 1981-12-22 3-Hydroxy-ethyl 1,3,4,5-tetra:hydro 1,3-benzodiazepine-2-thione(s) - and related cpds. are antidepressants, intermediate 2-amino-phenyl-ethyl-amino-ethanol derivs. are also new

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8123909A FR2518544A1 (en) 1981-12-22 1981-12-22 3-Hydroxy-ethyl 1,3,4,5-tetra:hydro 1,3-benzodiazepine-2-thione(s) - and related cpds. are antidepressants, intermediate 2-amino-phenyl-ethyl-amino-ethanol derivs. are also new

Publications (2)

Publication Number Publication Date
FR2518544A1 FR2518544A1 (en) 1983-06-24
FR2518544B1 true FR2518544B1 (en) 1984-02-10

Family

ID=9265252

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8123909A Granted FR2518544A1 (en) 1981-12-22 1981-12-22 3-Hydroxy-ethyl 1,3,4,5-tetra:hydro 1,3-benzodiazepine-2-thione(s) - and related cpds. are antidepressants, intermediate 2-amino-phenyl-ethyl-amino-ethanol derivs. are also new

Country Status (1)

Country Link
FR (1) FR2518544A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010068667A (en) * 2000-01-07 2001-07-23 박선호 Novel aliphatic amide having anticancer property
MXPA05013364A (en) * 2003-06-17 2006-03-17 Arena Pharm Inc Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases.
EP1619187A1 (en) * 2004-07-23 2006-01-25 Boehringer Ingelheim Pharma GmbH & Co. KG Process for the preparation of 3-(4-piperidinyl)- 2,3,4,5-tetrahydro-1,3-benzodiazepin-2(1H)-on
SI1879877T1 (en) 2005-05-03 2013-02-28 Ranbaxy Laboratories Limited Antimicrobial agents
SG10201508066VA (en) 2006-04-03 2015-10-29 Arena Pharm Inc Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
JP2009533315A (en) * 2006-04-10 2009-09-17 ランバクシー ラボラトリーズ リミテッド Antibacterial agent
ES2522587T3 (en) 2006-12-05 2014-11-17 Arena Pharmaceuticals, Inc. Processes for preparing (R) -8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzacepin and intermediates thereof
WO2009111004A1 (en) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
EP2611782A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
EP2611433A2 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
SG188365A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
KR20190128001A (en) 2012-10-09 2019-11-13 에자이 알앤드디 매니지먼트 가부시키가이샤 Method of weight management

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3310582A (en) * 1963-11-26 1967-03-21 Ciba Geigy Corp 2-aminophenyl-acetamides
US3474090A (en) * 1966-12-22 1969-10-21 American Cyanamid Co 3-aminoalkyl-1,3-benzodiazepin-2-ones
US3681340A (en) * 1968-02-12 1972-08-01 Herman Robert Rodriguez 1,3-benzodiazepines
US3838122A (en) * 1972-06-30 1974-09-24 J Suh 2-heterocyclic-1,3-benzodiazepines

Also Published As

Publication number Publication date
FR2518544A1 (en) 1983-06-24

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Legal Events

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ST Notification of lapse