FR2517953A1 - Diaphanometer for optical examination of breast tissue structure - measures tissue transparency using two plates and optical fibre bundle cooperating with photoelectric cells - Google Patents

Diaphanometer for optical examination of breast tissue structure - measures tissue transparency using two plates and optical fibre bundle cooperating with photoelectric cells Download PDF

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FR2517953A1
FR2517953A1 FR8123142A FR8123142A FR2517953A1 FR 2517953 A1 FR2517953 A1 FR 2517953A1 FR 8123142 A FR8123142 A FR 8123142A FR 8123142 A FR8123142 A FR 8123142A FR 2517953 A1 FR2517953 A1 FR 2517953A1
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light
tissue
plates
plate
connected
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FR8123142A
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French (fr)
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Claude Annonier
Gabriel Fazincani
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ALVAR ELECTRONIC
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ALVAR ELECTRONIC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/0059Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091Detecting, measuring or recording for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/103Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1079Measuring physical dimensions, e.g. size of the entire body or parts thereof using optical or photographic means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/43Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312Breast evaluation or disorder diagnosis

Abstract

The appts. is intended for determining the tissue structure of the breast by measuring the transparency of mammary tissue to visible light. The appts. measures simultaneously the light intensity and the thickness of tissue traversed. One of two plates (1,2) can slide parallel to the other on guiding rods (8) with mounting bushes (14). The plates are set up on either side of the port of the breast which is to be examined. One plate called the emitter plate (1) has on its internal face one end of an optical fibre bundle (15) contained in a sheath (3), the other end being connected to a light source. The bundle lies along an axis (13) normal to the plate. At the point where this axis intersects the receiver plate (2) there is situated a photosensitive cell (12) connected by a cable (4) to a light intensity meter (5). Information from a linear potentiometer (9) is also transmitted along the cable. The two plates are connected to each other by bellows (10) and by a shutter (11) to make the appts. light-proof.

Description

L'invention a pour objet un appareil diaphanométrique a usage d'investigations de nature médicale et/ou chirurgicale destiné à être utilisé plus spécialement en matière d'investigation d'affections de nature sénologique. The invention relates to a device has diaphanométrique use of a medical nature investigations and / or surgery to be used especially in the investigation of breast screening nature of diseases.

Toutefois, cet appareil peut comporter également des possibilités d'applications qui seront esquissées dans la suite de la description. However, this device may also have potential applications that will be outlined in the following description.

Plus spécialement, l'appareil selon l'invention est dérivé de la technique médicale d'observations diaphanoscopiques utilisées notamment pour le dépistage des lésions du sein. More specifically, the apparatus of the invention is derived from medical technology to diaphanoscopiques observations used in particular for the detection of breast lesions.

Plus spécialement encore, il est destiné a déterminer la structure tissulaire du sein. More especially, it is intended to determine the tissue structure of the breast.

Il doit être rappelé que la diaphanoscopie et les appareillages qui permettent de la réaliser ne permettent d'effectuer qu'une appréciation visuelle et subjective par le praticien et notamment ne permettent la constitution d'aucun document permanent, témoin de 1' examen, comme le sont les radiagraphies, les échographies ou les thermographies. It must be recalled that the diaphanoscopie and appliances that can realize not allow you to perform a visual and subjective assessment by the physician including only allow the creation of any permanent document witnessed one review, as are radiagraphies, ultrasounds or thermography.

Or il est évident que la détention de tels documents permanents est déterminante pour les comparaisons ultérieures qui peuvent avoir a être effectuées sur le même patient à raison de la même affection. Now it is evident that the detention of such permanent records is crucial for subsequent comparisons that may be made to the same patient because of the same condition.

La pratique quotidienne des examens diaphanoscopiques met en relief le fait frappant de la grande variabilité d'un sujet à l'autre, de la transparence du tissu mammaire à la lumière visible. The daily practice of diaphanoscopiques examinations highlights the striking fact of the great variability from one subject to another, transparency of breast tissue to visible light. Par ailleurs, et de façon intrigante, il a été constaté une absence de corrélation entre cette transparence et d'autres éléments d'appréciation de la densité mammaire telle que la fermeté-à la palpation et l'opacité aux rayons Moreover, and intriguingly, it was found no correlation between transparency and other factors for assessing breast density as firmness to palpation and opacity ray
X. X.

Ceci conduit à concevoir l'hypothèse d'un lien direct et significatif entre la transparence du sein à à la lumière visible et le type de structure qui la constitue. This leads to conceive the hypothesis of a direct and significant relationship between transparency breast to visible light and the type of structure that is. Or, si le tissu adipeux se laisse traverser avec autant de facilité par la lumière visible et les rayons X, il n'en est pas de même des autres constituants,du sein: l'eau joue un rôle prédominant dans l'obsorption aux rayons X alors qu'elle est transparente à la lumière. But if the fat lets through as easily visible light and X-rays, it is not the same with other components, breast: water plays a predominant role in the obsorption ray X while it is transparent to light. En revanche, les structures cellulaires sont opaques à la lumière visible tandis qu' elles apparaissent difficilement sur les mammographies. In contrast, cellular structures are opaque to visible light while that they hardly appear on mammograms.

Quant à la fermeté globale du sein à la palpation, elle subit de grandes variations liées à des facteurs qui échappent en partie à l'analyse, parmi lesquels la charge hydrique joue un rôle plus ou moins important. As for the overall firmness of the breast palpation, it undergoes large variations related to factors beyond in part to the analysis, including the water load plays a fairly important role.

De plus, il doit être constaté que l'estimation a l'oeil de la transparence du sein à la lumière est d'autant plus subjective que l'épaisseur de tissus traversée par cette lumière est très variable. In addition, it must be noted that the estimate Eye transparency within the light is more subjective than the thickness of tissue traversed by the light varies.

Il en résulte que, pour réaliser des investigations précises permettant l'utilisation de documents permanents et significatifs d'un état donné des tissus a une époque déterminée, il convenait de mettre au point un appareillage permettant l'établissement de tels documents permanents traduisant ou fournissant des paramètres de la transparence du sein à la lumière, comme il vient d'être exposé. As a result, for accurate investigations allowing the use of permanent records and significant a given state of the tissues has a specific time, it was necessary to develop an apparatus for establishing such permanent records reflecting or providing the parameters of the breast light transparency, as just described.

C'est la raison pour laquelle, avec cet objet en vue , l'invention concerne un appareillage aménagé de manière à mesurer simultanément l'intensité lumineuse efférente et l'épaisseur traversée des tissus. This is why, with this object in view, the invention relates to a apparatus arranged to simultaneously measure the efferent light intensity and the thickness traversed tissue.

Pour atteindre ce résultat, l'appareillage de mesure selon l'invention comporte deux plateaux parallèles destinés à être disposés de part et d'autre de la partie du sein que l'on se propose d'explorer, ces deux plateaux étant aménagés de manière a pouvoir être appliqués l'un et l'autre, toujours en position respectivement parallèle, contre ladite paroi du sein de manière que les éléments d'investigation qui vont être définis ci-après soient au contact de cette paroi. To achieve this result, the measuring apparatus according to the invention comprises two parallel plates to be arranged on either side of the part of the breast that it is intended to explore, these two plates being arranged so has to be applied one and the other, still respectively parallel position, against said wall of in a manner that the investigation elements that will be defined below are in contact with this wall.

Ces éléments d'investigation sont constitués, sur l'un des plateaux, qui sera désigné ci-après par 1' expression "plateau émetteur, par une source de lumière intense; cette source de lumière est, de préférence, constituée par l'extrémité d'un faisceau de fibres de verre, dites fibres optiques, qui la véhicule et l'intensité lumineuse est réglée de manière à n'occasionner aucune incommodité au patient pendant la durée de l'examen. Such investigative elements are constituted, on one of the plates, which will be hereinafter referred to by one term "sender plate, by a source of intense light, this light source is preferably constituted by the end a bundle of glass fibers, said optical fibers, that the vehicle and the light intensity is adjusted so as to not cause any discomfort to the patient during the duration of the examination.

L'autre plateau, dit "plateau récepteur" porte, de préférence dans l'axe du#faisceau de fibres optiques, une cellule photosensible reliée à un élément d'affichage et/ou de calcul de l'intensité lumineuse reçue par ladite cellule. The other plate, said "receiving plate" door, preferably in the axis of # optical fiber bundle, a photocell connected to a display element and / or of calculating the light intensity received by said cell.

Les deux plateaux sont l'un et l'autre reliés par un dispositif aménagé de manière à calculer et afficher la distance entre ceux-ci. The two plates are one and the other connected by a device arranged to calculate and display the distance therebetween.

La notation des deux éléments (intensité lumineuse efférente et distance séparant les deux plateaux), ainsi affichés sur l'appareil peut, après lecture de façon classique, être effectuée manuellement par le praticien. The notation of the two elements (efferent light intensity and distance between the two plates), and displayed on the device may, after a conventional manner of reading, be performed manually by the practitioner.

Cependant, selon une autre caractéristique de l'invention, les éléments d'affichage sont reliés à un dispositif d'appréciation. However, according to another characteristic of the invention, the display elements are connected to a judging device. Par ailleurs, l'appareillage peut être complété par un élément de calcul aménagé de manière à effectuer le rapport de mesure à une épaisseur type de tissus choisi et prédéterminé. Moreover, the apparatus can be completed by a computing element arranged to perform the measurement report to a typical thickness of predetermined and selected tissues.

Selon une autre caractéristique de l'appareillage selon l'invention, les deux plateaux sont reliés par des éléments d'étanchéité à la lumière, tels, par exemple, que des soufflets ou volets opaques aménagés de manière à permettre l'insertion du sein entre les dits plateaux. According to another characteristic of the apparatus according to the invention, the two plates are connected by sealing elements to light, such as, for example, as bellows or opaque flaps arranged as to allow insertion of the breast between said trays.

Encore selon une autre caractéristique de l'invention, des moyens peuvent être aménagés au niveau de la source lumineuse de manière à réduire l'étendue du spectre de lumière émis ou encore d'effectuer le mixage de plusieurs bandes étroites de fréquences. Still according to another feature of the invention, means may be arranged at the light source so as to reduce the extent of the transmitted light spectrum or to perform the mixing of several narrow frequency bands.

Il est connu qu'il a été démontré, notamment par les travaux du Dr LAMARQUE < MONTPELLIER) que les éponges végétales présentaient une texture qui peut être comparée à celle du sein, au moins dans le cadre de l'expérimentation en cause. It is known that it has been shown, especially by the work of Dr. LAMARQUE <MONTPELLIER) as vegetable sponge had a texture that can be compared to that of the breast, at least in the context of the experiment involved.

Il a été ainsi procédé à plusieurs expériences fondamentales à l'aide de telles éponges végétales. It was thus made several fundamental experiments using such vegetable sponge.

Dans une autre première expérience, une éponge à faces parallèles a été radiographiée deux fois dans des conditions techniques strictement identiques, une première fois à l'état sec puis une seconde fois après l'avoir imbibée d'eau; In another first experiment, a sponge with parallel faces was radiographed twice in a manner identical technical conditions, a first in the dry state and a second time after being soaked in water; l'appareillage selon l'invention permet de démontrer, comme il l'avait été fait par le Dr. LAMARQUE, mais cette fois-ci de façon chiffrée avec précision que l'éponge imbibée d'eau est beaucoup plus transparente à la lumière visible, que l'éponge sèche et dans un rapport de 465à 50 (les unités n'ayant ici qu'une valeur relative). the apparatus of the invention permits to demonstrate, as it had been done by Dr. LAMARQUE, but this time in encrypted form accurately the sponge soaked in water is much more transparent to visible light , the sponge dry and 465a in a ratio of 50 (units here having only a relative value).

La seconde e#xpérience a été faite avec deux éponges végétales à faces parallèles strictement identiques d'une épaisseur de 18 mm. The second e # xperience was made with two vegetable sponges strictly identical parallel faces with a thickness of 18 mm. placées dans une boite de matière plastique contenant une hauteur d'eau constante de 40 mm. placed in a plastic dish containing a constant water head of 40 mm.

Dans une première phase de l'expérience, une seule des deux éponges a été disposée dans la boite de ma tière plastique et les deux éponges ont été simultanément placées face à face, dans ladite boite, au cours de la seconde partie de l'expérience. In a first phase of the experiment, only one of the sponges has been disposed in the box of my plastic RESPECT and two sponges were simultaneously placed face to face, in said box, in the second part of the experiment . L'on a pu alors constater que, pour une même épaisseur d'eau, la densité radiologique était pratiquement identique alors que, par contre, la diaphanométrie effectuée avec l'appareillage selon l'invention donnait un rapport de transparence de 138 avec une éponge, à 16 avec deux éponges. One could then see that, for the same depth of water, radiation density was substantially the same as, for against the diaphanométrie performed with the apparatus according to the invention gave a ratio of transparency 138 with a sponge , 16 with two sponges. Cette expérience met particulière- ment en évidence le fait que la diaphanoscopie, notamment lorsqu'elle est effectuée avec l'appareillage selon l'invention, permet une meilleure appréciation quantitative des structures que l'analyse par les rayons X. This experiment lies particularly highlight the fact that the diaphanoscopie, especially when performed with the apparatus of the invention allows a better quantitative assessment of structures that the analysis by X-rays

L'expérimentation clinique effectuée sur un grand nombre de seins a montré qu'il convenait d'exprimer le résultat fourni par l'appareil, c'est-à-dire essentiellement la mesure de l'intensité lumineuse de sortie, en watt/m2, ce qui permet de définir le coefficient d'absorption, ce coefficient d'absorption étant calculable à partir de l'épaisseur de tissus mesurée. The clinical experimentation carried out on a large number of breasts showed that it was appropriate to express the result provided by the apparatus, that is to say essentially the measurement of the light output intensity in watts / m2 , which sets the coefficient of absorption, coefficient of absorption being calculable from the measured thickness of tissue.

Ces expérimentations cliniques ont également établi que la gamme des valeurs de transparence ou de transmissibilité lumineuse pouvait s'établir entre des valeurs extrêmes très éloignées. These clinical trials have also shown that the range of values ​​of transparency or light transmissibility could take place between very distant extremes. Il est ainsi apparu que 11 appareillage selon l'invention permettait de déceler des différences très significatives d'un type de structure à l'autre. It thus appeared that 11 apparatus of the invention allow to detect very significant differences of a structural type to another. Par exemple, pour une épaisseur mesurée de 50 mm. For example, for a measured thickness of 50 mm. la valeur du faisceau de sortie mesurée en watt/m2 va de 0,17 milliwatt/m2 pour une mastose sévère, précédemment identifiée par d'autres moyens, à 1,13 pour un syndrome fonctionnel d'une jeune femme. the value of the output beam measured in watt / m 2 is from 0.17 milliwatt / m2 for severe fibrocystic breast, previously identified by other means, to 1.13 for a block of a young woman syndrome.

Les mêmes expérimentations cliniques ont établi que la diaphanométrie (c'est-à-dire la diaphanoscopie effectuée à l'aide d'un appareillage permettant d'en mesurer les paramètres) présentait une valeur indicatrice certaine de richesse cellulaire - un sein raciiotransparent est toujours transparent à la lumière, - un sein présentant radiologiquement un aspect de mastose, vraie fibro-nodulaire, est toujours fortement opaque à la lumière - un sein opaques la mammographie est tantôt transparent à la lumière (cas fréquent chez les jeunes femmes) tantôt opaque, évoquant une surcharge cellulaire. The same clinical trials have established that diaphanométrie (that is to say the diaphanoscopie performed using equipment to measure their parameters) showed some value indicative of cellular wealth - is still breast raciiotransparent transparent to light, - breast with radiologically an aspect of fibrocystic breast, real fibro-nodular, is still highly opaque to light - an opaque breast mammography is now transparent to light (frequent in young women) sometimes opaque, evoking a cell overload.

Or, l'appareillage de diaphanométrie selon l'invention présente l'intérêt d'être constitué par un matériel peu couteux et grâce auquel une mesure ne demande que quelques secondes et n'exige pas l'obscurité, ce qui permet d'effectuer à très peu de frais la sélection de structures mammaires à risque de cancer dans le cadre d'une opération de dépistage. However, the apparatus of diaphanométrie according to the invention has the advantage of being constituted by an inexpensive material and through which a measurement takes only a few seconds and does not require darkness, which allows to very inexpensively selecting breast cancer risk structures as part of a screening program.

L'invention sera bien comprise à la lecture de la description qui va suivre faite en référence au dessin annexé dans lequel la figure unique est une vue schématique d'un appareil de diaphanométrie conforme aux définitions qui précèdent. The invention will be better understood on reading the following description made with reference to the accompanying drawing wherein the single figure is a schematic view of a diaphanométrie device conforming to the above definitions.

Sur la figure unique, l'appareil de diaphanométrie comporte deux plateaux 1, 2, qui peuvent coulisser de façon parallèle sur des tiges de guidage 8. En principe et comme il est représenté sur la figure, les tiges 8 sont solidaires du plateau 1 et seul le#pla- teau 2 y est monté coulissant par les bagues de guidage 14. In the single figure, the diaphanométrie apparatus comprises two plates 1, 2, which are slidable in parallel to the guide rods 8. In principle, and as shown in the figure, the rods 8 are integral with the plate 1 and only the ceiling cake # 2 is slidably mounted by the guide rings 14.

Le plateau 1, ou plateau émetteur, porte à sa partie inférieure une arrivée 15 des fibres optiques contenues dans une gaine 3 reliée à une source de lumière qui n'a pas été représentée. The plate 1, or sender plate, carries at its lower portion an inlet 15 of optical fibers contained in a sheath 3 connected to a light source which is not shown.

Le faisceau de fibres optiques débouche sur la face interne du plateau émetteur, de façon normale à ce dernier, selon un axe 13 qui a été représenté en traits mixtes à la figure. The optical fiber bundle opens out on the inner face of the emitter plate, normal to the latter, along an axis 13 which has been shown in phantom in FIG.

A l'endroit ou l'axe 14 intersecte le plateau récepteur 2, celui-ci est muni d'une cellule photosensible 12, dont l'élément capteur est orienté en direction de l'arrivée 15 du faisceau de fibres optiques. At the place where the axis 14 intersects the receiver plate 2, the latter is provided with a photosensitive cell 12, the sensor element is oriented in the direction of arrival 15 of the optical fiber bundle. La cellule photosensible est reliée à un élément d'affichage et de calcul de l'intensité lumineuse 6, dépendant d'un boitier de mesure désigné par la référence générale 5 et dans lequel est disposé un élément de calcul 7 aménagé de manière à afficher la distance séparant les deux plateaux.-Cet affichage est obtenu à partir d'un potentiomètre linéaire 9 qui traverse le plateau 3 par un ajour 9b convenable et est solidaire par son extrémité 9a du plateau émetteur 1, le curseur dudit potentiomètre, ici non représenté, est solidaire du plateau récepteur 2 et les informations qu'il fournit sont transmises par le faisceau de fils conducteurs 4 qui véhicule également les informations électriques reçues de la cellule photosensible 13 pour diriger ces dernières sur 1' élément d'affichage 6. The photosensitive cell is connected to a display element and calculating the light intensity 6, depending on a case of measurement designated by the general reference 5 and in which is arranged a computing element 7 arranged to display the distance between the two plateaux. This display is obtained from a linear potentiometer 9 which passes through the plate 3 by an opening 9b suitable and is secured by its end 9a of the emitter plate 1, the cursor of said potentiometer, not shown here, is integral with the receiving plate 2 and the information it provides are transmitted by the beam son conductors 4 which also carries the electrical information received from the light sensor 13 to direct the last of 1 'display element 6.

L'appareillage est amené au dessus du sein de la pat ente, de manière le surmonter et à l'y introduire en S. The equipment is brought above within the pat ente so overcome it and introduce in S.

L'appareil comporte en outre, de part et d'autre des plateaux 1,2, des soufflets 10 étanches à la lumière et il est muni d'un volet également opaque 11 aménagé à sa partie supérieure et articulé dans l'exemple, sur le plateau 1. The apparatus further comprises, on either side of the plates 1,2, 10 sealed bellows to light and it is also provided with an opaque flap 11 arranged in its upper part and articulated in the example, on the plate 1.

Bien entendu, lors de la mise en place sur le sein de la patiente, les deux plateaux 1,2, sont préalablement disposés au voisinage de leur position d'écartement relatif extrême et ils sont ensuite rapprochés l'un de l'autre de manière que, comme il a été dit dans l'introduction, l'orifice d'arrivée 15 et l'élément capteur de la cellule photosensible 12 sont appliqués l'un et l'autre contre le sein de la patiente. Of course, during the implementation on the breast of the patient, the two plates 1,2 are first placed in the vicinity of their spacing relative end position and are then moved toward each other so that, as it was said in the introduction, the supply port 15 and the sensor element of the light-sensitive cell 12 are pressed and the other against the breast of the patient.

Claims (1)

  1. REVENDICATION CLAIM
    Appareil à usage d'investigations de nature médicale et/ou chirurgicale destiné à être utilisé plus spécialement en matière d'investigation d'affections de nature sénologique et dérivé de la technique connue de l'observation diaphanoscopique utilisée notamment pour le dépistage des lésions du sein, caractérisé en ce qu'il comporte deux plateaux parallèles destinés à être disposés de part et d'autre de la partie du sein que l'on se propose d'explorer, ces deux plateaux étant aménagés de manière à pouvoir être appliqués l'un et l'autre, toujours en position respectivement parallèle, contre--ladite paroi du sein de manière que les éléments d'investigation constitués sur l'un des plateaux, désigné ci-après par l'expres- sion "plateau émetteur", par une source de lumière intense de préférence constituée par l'extrémité d'un faisceau de fibres de verre, dites fibres optiques, convenablement relié à un émetteur lumineux, tandis que l'autre plateau Device to use medical nature of investigations and / or surgery to be used especially in the investigation of breast screening nature of affections and derivative technique known diaphanoscopique observation used in particular for the detection of breast lesions characterized in that it comprises two parallel plates to be arranged on either side of the part of the breast that it is intended to explore, these two plates being arranged so as to be applied one and the other always in respectively parallel position against - said wall breast so that investigative elements constituted on one of the plates, hereinafter referred to by the expression sion "sender plate", by an intense light source preferably consists of the end of a bundle of glass fibers, said optical fibers, suitably connected to a light emitter, while the other plate , dit "plateau récepteur" porte de préférence dans l'axe du faisceau de fibres optiques, une cellule photose#nsible reliée à un élément d'affichage et/ou de calcul de l'intensité lumineuse reçue par ladite cellule, les deux plateaux étant l'un et l'autre reliés par un dispositif aménagé de manière à calculer et afficher la distance entre ceuxci et que les deux plateaux sont reliés par des éléments d'étanchéité à la lumière tels, par exemple, que des soufflets et/ou des volets opaques aménagés de manière à permettre l'insertion du sein entre les dits plateaux. Said "receiving plate" Any door in the axis of the optical fiber bundle, a photose # nsible cell connected to a display element and / or of calculating the light intensity received by said cell, the two plates being one and the other connected by a device arranged to calculate and display the distance between ceuxci and the two plates are connected by sealing elements in such light, for example, as bellows and / or opaque flaps arranged as to allow the insertion of the breast between said plates.
FR8123142A 1981-12-10 1981-12-10 Diaphanometer for optical examination of breast tissue structure - measures tissue transparency using two plates and optical fibre bundle cooperating with photoelectric cells Withdrawn FR2517953A1 (en)

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Cited By (288)

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