FR2504925A1 - N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia - Google Patents

N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia Download PDF

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Publication number
FR2504925A1
FR2504925A1 FR8108809A FR8108809A FR2504925A1 FR 2504925 A1 FR2504925 A1 FR 2504925A1 FR 8108809 A FR8108809 A FR 8108809A FR 8108809 A FR8108809 A FR 8108809A FR 2504925 A1 FR2504925 A1 FR 2504925A1
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FR
France
Prior art keywords
sep
radical
alkoxy
phenoxy
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8108809A
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English (en)
French (fr)
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FR2504925B1 (US06299757-20011009-C00006.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre Europeen de Recherches Mauvernay CERM
Original Assignee
Centre Europeen de Recherches Mauvernay CERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Europeen de Recherches Mauvernay CERM filed Critical Centre Europeen de Recherches Mauvernay CERM
Priority to FR8108809A priority Critical patent/FR2504925A1/fr
Publication of FR2504925A1 publication Critical patent/FR2504925A1/fr
Application granted granted Critical
Publication of FR2504925B1 publication Critical patent/FR2504925B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/40—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8108809A 1981-05-04 1981-05-04 N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia Granted FR2504925A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8108809A FR2504925A1 (en) 1981-05-04 1981-05-04 N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8108809A FR2504925A1 (en) 1981-05-04 1981-05-04 N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia

Publications (2)

Publication Number Publication Date
FR2504925A1 true FR2504925A1 (en) 1982-11-05
FR2504925B1 FR2504925B1 (US06299757-20011009-C00006.png) 1984-03-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
FR8108809A Granted FR2504925A1 (en) 1981-05-04 1981-05-04 N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia

Country Status (1)

Country Link
FR (1) FR2504925A1 (US06299757-20011009-C00006.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645778A (en) * 1983-09-27 1987-02-24 Riom Laboratoires C.E.R.M. "Rl-Cerm"S.A. 2-(N-pyrrolidino)-3-isobutoxy-n-substituted-phenyl-n-benzyl-propylamines, their preparation and pharmaceutical use
EP0295010A1 (en) * 1987-06-10 1988-12-14 A.H. Robins Company, Incorporated Derivatives of alkylaminoalkyl ureas and cyanoguanidines

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1936476A1 (de) * 1968-07-17 1970-02-26 Ct Europ De Rech S Mauvernay S Neue Amide,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten
FR2326179A1 (fr) * 1975-09-30 1977-04-29 Cerm Cent Europ Rech Mauvernay Nouveaux ethers de propanolamines utilisables dans le traitement des maladies cardiovasculaires

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1936476A1 (de) * 1968-07-17 1970-02-26 Ct Europ De Rech S Mauvernay S Neue Amide,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten
FR2326179A1 (fr) * 1975-09-30 1977-04-29 Cerm Cent Europ Rech Mauvernay Nouveaux ethers de propanolamines utilisables dans le traitement des maladies cardiovasculaires

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645778A (en) * 1983-09-27 1987-02-24 Riom Laboratoires C.E.R.M. "Rl-Cerm"S.A. 2-(N-pyrrolidino)-3-isobutoxy-n-substituted-phenyl-n-benzyl-propylamines, their preparation and pharmaceutical use
EP0295010A1 (en) * 1987-06-10 1988-12-14 A.H. Robins Company, Incorporated Derivatives of alkylaminoalkyl ureas and cyanoguanidines

Also Published As

Publication number Publication date
FR2504925B1 (US06299757-20011009-C00006.png) 1984-03-16

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Legal Events

Date Code Title Description
ER Errata listed in the french official journal (bopi)
CD Change of name or company name
ST Notification of lapse