FR2502783A1 - Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ - Google Patents
Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ Download PDFInfo
- Publication number
- FR2502783A1 FR2502783A1 FR8105948A FR8105948A FR2502783A1 FR 2502783 A1 FR2502783 A1 FR 2502783A1 FR 8105948 A FR8105948 A FR 8105948A FR 8105948 A FR8105948 A FR 8105948A FR 2502783 A1 FR2502783 A1 FR 2502783A1
- Authority
- FR
- France
- Prior art keywords
- axis
- laser generator
- optical
- radiation
- organ
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000005855 radiation Effects 0.000 title claims abstract description 43
- 230000033116 oxidation-reduction process Effects 0.000 title claims abstract description 8
- 238000005259 measurement Methods 0.000 title description 5
- 210000000056 organ Anatomy 0.000 claims abstract description 38
- 239000000835 fiber Substances 0.000 claims abstract description 11
- 230000003287 optical effect Effects 0.000 claims description 34
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 10
- 238000012545 processing Methods 0.000 claims description 10
- 239000013307 optical fiber Substances 0.000 claims description 9
- 210000003743 erythrocyte Anatomy 0.000 claims description 7
- 238000005286 illumination Methods 0.000 claims description 7
- 238000011065 in-situ storage Methods 0.000 claims description 6
- 229910052757 nitrogen Inorganic materials 0.000 claims description 5
- 238000011846 endoscopic investigation Methods 0.000 abstract 1
- 239000000975 dye Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 230000000747 cardiac effect Effects 0.000 description 6
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 5
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 238000005070 sampling Methods 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 238000011477 surgical intervention Methods 0.000 description 2
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000005253 cladding Methods 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000001174 endocardium Anatomy 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000010365 information processing Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 230000003071 parasitic effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
- 230000001960 triggered effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Optics & Photonics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8105948A FR2502783A1 (fr) | 1981-03-25 | 1981-03-25 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
FR8202323A FR2521727A2 (fr) | 1981-03-25 | 1982-02-12 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
DE19823210593 DE3210593A1 (de) | 1981-03-25 | 1982-03-23 | Vorrichtung zum messen des oxido-reduktionszustands eines organs am lebenden objekt |
JP57047054A JPS57188242A (en) | 1981-03-25 | 1982-03-24 | Apparatus for measuring redox condition of active organ in live body |
US06/362,012 US4449535A (en) | 1981-03-25 | 1982-03-25 | Apparatus for measuring in situ the state of oxidation-reduction of a living organ |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8105948A FR2502783A1 (fr) | 1981-03-25 | 1981-03-25 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2502783A1 true FR2502783A1 (fr) | 1982-10-01 |
FR2502783B1 FR2502783B1 (enrdf_load_stackoverflow) | 1984-10-26 |
Family
ID=9256629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8105948A Granted FR2502783A1 (fr) | 1981-03-25 | 1981-03-25 | Dispositif pour mesurer l'etat d'oxydo-reduction d'un organe vivant in situ |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS57188242A (enrdf_load_stackoverflow) |
FR (1) | FR2502783A1 (enrdf_load_stackoverflow) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0296259A1 (en) * | 1987-06-22 | 1988-12-28 | Pacific Scientific Company | Spectrometer with combined visible and ultraviolet sample illumination |
US5040889A (en) * | 1986-05-30 | 1991-08-20 | Pacific Scientific Company | Spectrometer with combined visible and ultraviolet sample illumination |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6075032A (ja) * | 1983-09-30 | 1985-04-27 | アロカ株式会社 | レ−ザ光による生化学成分分析装置 |
CN85100424B (zh) * | 1985-04-01 | 1986-10-29 | 上海医疗器械研究所 | 恶性肿瘤固有荧光诊断仪 |
EP1744661B1 (en) * | 2004-04-30 | 2013-04-10 | Koninklijke Philips Electronics N.V. | Probe head for spectroscopic analysis of a fluid |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3811777A (en) * | 1973-02-06 | 1974-05-21 | Johnson Res Foundation Medical | Time-sharing fluorometer and reflectometer |
FR2229063A1 (enrdf_load_stackoverflow) * | 1973-05-07 | 1974-12-06 | Atomic Energy Commission | |
EP0003015A1 (en) * | 1978-01-03 | 1979-07-11 | Howard Maurice Shapiro | Apparatus for non-invasive detection of zinc protoporphyrin in erythrocytes |
JPS5628778A (en) * | 1979-08-15 | 1981-03-20 | Hitoji Sakuma | Shuttle cock for badminton and its manufacture and its manufacturing device |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5216358A (en) * | 1975-07-24 | 1977-02-07 | Kubota Ltd | Thresher |
JPS53135660A (en) * | 1977-04-30 | 1978-11-27 | Olympus Optical Co Ltd | Fluorescent photometric microscope using laser light |
JPS5546726A (en) * | 1979-09-25 | 1980-04-02 | Canon Inc | Daytime flash pohotographing device |
-
1981
- 1981-03-25 FR FR8105948A patent/FR2502783A1/fr active Granted
-
1982
- 1982-03-24 JP JP57047054A patent/JPS57188242A/ja active Granted
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3811777A (en) * | 1973-02-06 | 1974-05-21 | Johnson Res Foundation Medical | Time-sharing fluorometer and reflectometer |
FR2229063A1 (enrdf_load_stackoverflow) * | 1973-05-07 | 1974-12-06 | Atomic Energy Commission | |
US3918812A (en) * | 1973-05-07 | 1975-11-11 | Us Energy | Diagnoses of disease states by fluorescent measurements utilizing scanning laser beams |
EP0003015A1 (en) * | 1978-01-03 | 1979-07-11 | Howard Maurice Shapiro | Apparatus for non-invasive detection of zinc protoporphyrin in erythrocytes |
JPS5628778A (en) * | 1979-08-15 | 1981-03-20 | Hitoji Sakuma | Shuttle cock for badminton and its manufacture and its manufacturing device |
Non-Patent Citations (4)
Title |
---|
ABJP/78 * |
EXBK/71 * |
EXBK/76 * |
EXBK/79 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5040889A (en) * | 1986-05-30 | 1991-08-20 | Pacific Scientific Company | Spectrometer with combined visible and ultraviolet sample illumination |
EP0296259A1 (en) * | 1987-06-22 | 1988-12-28 | Pacific Scientific Company | Spectrometer with combined visible and ultraviolet sample illumination |
Also Published As
Publication number | Publication date |
---|---|
JPH027653B2 (enrdf_load_stackoverflow) | 1990-02-20 |
FR2502783B1 (enrdf_load_stackoverflow) | 1984-10-26 |
JPS57188242A (en) | 1982-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AM | Act modifying the rights related to an application or a patent | ||
AM | Act modifying the rights related to an application or a patent | ||
TP | Transmission of property | ||
ST | Notification of lapse |