FR2500440B1 - - Google Patents

Info

Publication number
FR2500440B1
FR2500440B1 FR8103521A FR8103521A FR2500440B1 FR 2500440 B1 FR2500440 B1 FR 2500440B1 FR 8103521 A FR8103521 A FR 8103521A FR 8103521 A FR8103521 A FR 8103521A FR 2500440 B1 FR2500440 B1 FR 2500440B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8103521A
Other languages
French (fr)
Other versions
FR2500440A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR8103521A priority Critical patent/FR2500440A1/fr
Priority to IT47843/82A priority patent/IT1189226B/it
Priority to CH1081/82A priority patent/CH658048A5/fr
Priority to DE19823206426 priority patent/DE3206426A1/de
Priority to GB8205255A priority patent/GB2093838B/en
Priority to JP57026929A priority patent/JPS57156431A/ja
Publication of FR2500440A1 publication Critical patent/FR2500440A1/fr
Application granted granted Critical
Publication of FR2500440B1 publication Critical patent/FR2500440B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/487Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C07C49/737Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having three rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FR8103521A 1981-02-23 1981-02-23 Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, et leur procede de preparation ainsi que des produits intermediaires Granted FR2500440A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR8103521A FR2500440A1 (fr) 1981-02-23 1981-02-23 Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, et leur procede de preparation ainsi que des produits intermediaires
IT47843/82A IT1189226B (it) 1981-02-23 1982-02-22 Medicamenti e prodotti derivati da 3-idrossidodecaidro benz(e) inden-7-one bisostituiti in posizione 6,procedimento di preparazione e intermedi ottenuti
CH1081/82A CH658048A5 (fr) 1981-02-23 1982-02-22 Medicaments et composes derives de la 3-hydroxy dodecahydro benz(e) inden-7-one disubstituee en position 6 et leur procede de preparation.
DE19823206426 DE3206426A1 (de) 1981-02-23 1982-02-23 Neue arzneimittel und neue produkte, die sich von in 6-stellung disubstituiertem 3-hydroxydodecahydrobenz(e)inden-7-on ableiten, herstellungsverfahren und erhaltene neue zwischenprodukte
GB8205255A GB2093838B (en) 1981-02-23 1982-02-23 Dodecahydro benz(e) inden-7-one medicaments
JP57026929A JPS57156431A (en) 1981-02-23 1982-02-23 Novel drugs and novel compounds comprising 6-position bisubstituted 3-hydroxydodeca hydrobenzo(e)indene-7-one, manufacture and obtained novel intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8103521A FR2500440A1 (fr) 1981-02-23 1981-02-23 Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, et leur procede de preparation ainsi que des produits intermediaires

Publications (2)

Publication Number Publication Date
FR2500440A1 FR2500440A1 (fr) 1982-08-27
FR2500440B1 true FR2500440B1 (US20030199744A1-20031023-C00003.png) 1984-05-25

Family

ID=9255515

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8103521A Granted FR2500440A1 (fr) 1981-02-23 1981-02-23 Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one disubstituee en position 6, et leur procede de preparation ainsi que des produits intermediaires

Country Status (6)

Country Link
JP (1) JPS57156431A (US20030199744A1-20031023-C00003.png)
CH (1) CH658048A5 (US20030199744A1-20031023-C00003.png)
DE (1) DE3206426A1 (US20030199744A1-20031023-C00003.png)
FR (1) FR2500440A1 (US20030199744A1-20031023-C00003.png)
GB (1) GB2093838B (US20030199744A1-20031023-C00003.png)
IT (1) IT1189226B (US20030199744A1-20031023-C00003.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3369965D1 (en) * 1982-11-10 1987-04-09 Ici Plc Aphidicolane derivatives, their preparation and pharmaceutical compositions comprising them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791184A (fr) * 1971-11-12 1973-05-10 Hoffmann La Roche Procede pour la preparation de desa-steroides
US3984474A (en) * 1975-05-30 1976-10-05 E. R. Squibb & Sons, Inc. 4,5-Secoandrostanes
CA1195997A (en) * 1979-02-23 1985-10-29 Andor Furst Dea-steroids

Also Published As

Publication number Publication date
IT1189226B (it) 1988-01-28
CH658048A5 (fr) 1986-10-15
IT8247843A0 (it) 1982-02-22
FR2500440A1 (fr) 1982-08-27
DE3206426A1 (de) 1982-09-09
JPS57156431A (en) 1982-09-27
GB2093838B (en) 1985-11-06
GB2093838A (en) 1982-09-08

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Legal Events

Date Code Title Description
ST Notification of lapse