FR2479825B1 - - Google Patents

Info

Publication number
FR2479825B1
FR2479825B1 FR8007719A FR8007719A FR2479825B1 FR 2479825 B1 FR2479825 B1 FR 2479825B1 FR 8007719 A FR8007719 A FR 8007719A FR 8007719 A FR8007719 A FR 8007719A FR 2479825 B1 FR2479825 B1 FR 2479825B1
Authority
FR
France
Prior art keywords
benzodioxan
produce
novel process
lower alkyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8007719A
Other languages
English (en)
French (fr)
Other versions
FR2479825A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Priority to FR8007719A priority Critical patent/FR2479825A1/fr
Priority to ES500822A priority patent/ES500822A0/es
Priority to US06/250,407 priority patent/US4456614A/en
Priority to AT81400529T priority patent/ATE5722T1/de
Priority to EP81400529A priority patent/EP0037778B1/fr
Priority to DE8181400529T priority patent/DE3161750D1/de
Priority to DK153581A priority patent/DK152288C/da
Priority to JP5103681A priority patent/JPS56156275A/ja
Priority to CA000374619A priority patent/CA1167047A/fr
Priority to ZA00812263A priority patent/ZA812263B/xx
Priority to AU69099/81A priority patent/AU543364B2/en
Publication of FR2479825A1 publication Critical patent/FR2479825A1/fr
Priority to US06/455,125 priority patent/US4539413A/en
Application granted granted Critical
Publication of FR2479825B1 publication Critical patent/FR2479825B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
FR8007719A 1980-04-04 1980-04-04 Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments Granted FR2479825A1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8007719A FR2479825A1 (fr) 1980-04-04 1980-04-04 Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments
ES500822A ES500822A0 (es) 1980-04-04 1981-03-28 Procedimiento de preparar derivados propanolaminicos
AT81400529T ATE5722T1 (de) 1980-04-04 1981-04-02 2-(1,4-benzodioxanyl)-methoxy-propanolamine, verfahren zu deren herstellung und verwendung als arzneimittel.
EP81400529A EP0037778B1 (fr) 1980-04-04 1981-04-02 Benzodioxanne 1,4 méthoxy-2 propanolamines, leur préparation et leur application en tant que médicaments
DE8181400529T DE3161750D1 (en) 1980-04-04 1981-04-02 2-(1,4-benzodioxanyl)-methoxy-propanol amines, process for their preparation and their use as medicines
US06/250,407 US4456614A (en) 1980-04-04 1981-04-02 3-Amino-1-[(1,4-benzodioxan)-2-yl-methoxy]-2-propanols, pharmaceutical compositions thereof, and their use as medicaments
DK153581A DK152288C (da) 1980-04-04 1981-04-03 Analogifremgangsmaade til fremstilling af 3-(1,4-benzodioxan-2-yl-methoxy)-2-propanolaminer eller syreadditionssalte deraf
JP5103681A JPS56156275A (en) 1980-04-04 1981-04-03 1,4-benzodioxane-2-methoxypropanol amines, their manufacture and medicine containing them
CA000374619A CA1167047A (fr) 1980-04-04 1981-04-03 Benzodioxanne l,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments
ZA00812263A ZA812263B (en) 1980-04-04 1981-04-03 1,4 benzodiozan 2-methoxy propanolamines, their preparation, and their application as drugs
AU69099/81A AU543364B2 (en) 1980-04-04 1981-04-06 Benzodioxan-1,4-methoxy-2-propanolamines
US06/455,125 US4539413A (en) 1980-04-04 1983-01-03 Preparation of 3-amino-1-[(1,4-benzodioxan)-2-yl-methoxy]-2-propanols

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8007719A FR2479825A1 (fr) 1980-04-04 1980-04-04 Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments

Publications (2)

Publication Number Publication Date
FR2479825A1 FR2479825A1 (fr) 1981-10-09
FR2479825B1 true FR2479825B1 (enrdf_load_stackoverflow) 1983-07-08

Family

ID=9240576

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8007719A Granted FR2479825A1 (fr) 1980-04-04 1980-04-04 Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments

Country Status (11)

Country Link
US (2) US4456614A (enrdf_load_stackoverflow)
EP (1) EP0037778B1 (enrdf_load_stackoverflow)
JP (1) JPS56156275A (enrdf_load_stackoverflow)
AT (1) ATE5722T1 (enrdf_load_stackoverflow)
AU (1) AU543364B2 (enrdf_load_stackoverflow)
CA (1) CA1167047A (enrdf_load_stackoverflow)
DE (1) DE3161750D1 (enrdf_load_stackoverflow)
DK (1) DK152288C (enrdf_load_stackoverflow)
ES (1) ES500822A0 (enrdf_load_stackoverflow)
FR (1) FR2479825A1 (enrdf_load_stackoverflow)
ZA (1) ZA812263B (enrdf_load_stackoverflow)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2479825A1 (fr) * 1980-04-04 1981-10-09 Fabre Sa Pierre Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments
CA1220059A (en) * 1983-10-03 1987-04-07 Edmund Isakov Two-prong rotary bit, especially for use with roof drills, and insert therefor
ATE182367T1 (de) * 1992-12-21 1999-08-15 Duphar Int Res Enzymatisches verfahren zur stereoselektiven herstellung einem enantiomer aus einem hetero bicyclischen alkohols
AR049646A1 (es) * 2004-06-16 2006-08-23 Janssen Pharmaceutica Nv Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados
MY147767A (en) * 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
AU2005277134A1 (en) * 2004-08-24 2006-03-02 Janssen Pharmaceutica N.V. Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents
EA200702558A1 (ru) * 2005-05-20 2008-06-30 Янссен Фармацевтика Н. В. Способ получения производных сульфамида
US8497298B2 (en) * 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
AR058389A1 (es) * 2005-12-19 2008-01-30 Janssen Pharmaceutica Nv Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad
US8691867B2 (en) * 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US20070155823A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents
US8937096B2 (en) * 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US20070155827A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
WO2007137167A2 (en) * 2006-05-19 2007-11-29 Janssen Pharmaceutica N.V. Co-therapy for the treatment of epilepsy
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
US20090247618A1 (en) * 2008-03-26 2009-10-01 Ballentine Scott A Process for preparation of benzo-fused heteroaryl derivatives
NZ590682A (en) * 2008-06-23 2012-09-28 Janssen Pharmaceutica Nv Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide
US8815939B2 (en) * 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL281245A (enrdf_load_stackoverflow) * 1962-07-20
GB1100960A (en) * 1963-06-20 1968-01-31 Ward Blenkinsop & Co Ltd 1,4-benzodioxane derivatives
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
GB1521471A (en) * 1974-06-05 1978-08-16 Randall & Son Ltd J Token-deposit locks
FR2358142A1 (fr) * 1976-07-12 1978-02-10 Parcor Nouveaux derives du benzodioxanne
JPS5377081A (en) * 1976-12-20 1978-07-08 Yoshitomi Pharmaceut Ind Ltd 1,4-benzodioxepin derivative, its acid addition salt, and its preparation
US4187313A (en) * 1978-01-30 1980-02-05 Ciba-Geigy Corporation 2-Aminoethyl-1,4-benzodioxans
US4261907A (en) * 1978-01-30 1981-04-14 Ciba-Geigy Corporation Stereospecific process
FR2479825A1 (fr) * 1980-04-04 1981-10-09 Fabre Sa Pierre Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments

Also Published As

Publication number Publication date
EP0037778A1 (fr) 1981-10-14
DK152288B (da) 1988-02-15
CA1167047A (fr) 1984-05-08
DK152288C (da) 1988-07-11
EP0037778B1 (fr) 1983-12-28
ES8201572A1 (es) 1982-01-01
JPS56156275A (en) 1981-12-02
JPS649994B2 (enrdf_load_stackoverflow) 1989-02-21
ZA812263B (en) 1982-04-28
AU543364B2 (en) 1985-04-18
US4456614A (en) 1984-06-26
DK153581A (da) 1981-10-05
AU6909981A (en) 1981-10-08
ES500822A0 (es) 1982-01-01
ATE5722T1 (de) 1984-01-15
DE3161750D1 (en) 1984-02-02
US4539413A (en) 1985-09-03
FR2479825A1 (fr) 1981-10-09

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