FR2463143B1 - - Google Patents

Info

Publication number
FR2463143B1
FR2463143B1 FR8017582A FR8017582A FR2463143B1 FR 2463143 B1 FR2463143 B1 FR 2463143B1 FR 8017582 A FR8017582 A FR 8017582A FR 8017582 A FR8017582 A FR 8017582A FR 2463143 B1 FR2463143 B1 FR 2463143B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8017582A
Other languages
French (fr)
Other versions
FR2463143A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of FR2463143A1 publication Critical patent/FR2463143A1/fr
Application granted granted Critical
Publication of FR2463143B1 publication Critical patent/FR2463143B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8017582A 1979-08-08 1980-08-08 Nouveaux 7-phenyl-(1,2,4) - triazolo-(4,3-c) - pyrimidine-5-yl-amines et amides 8-substitues, utiles notamment comme diuretiques, et leur procede de preparation Granted FR2463143A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6470779A 1979-08-08 1979-08-08

Publications (2)

Publication Number Publication Date
FR2463143A1 FR2463143A1 (fr) 1981-02-20
FR2463143B1 true FR2463143B1 (it) 1983-12-16

Family

ID=22057763

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8017582A Granted FR2463143A1 (fr) 1979-08-08 1980-08-08 Nouveaux 7-phenyl-(1,2,4) - triazolo-(4,3-c) - pyrimidine-5-yl-amines et amides 8-substitues, utiles notamment comme diuretiques, et leur procede de preparation

Country Status (7)

Country Link
JP (1) JPS5632479A (it)
AU (1) AU531507B2 (it)
CA (2) CA1246063A (it)
CH (1) CH645898A5 (it)
DE (1) DE3029871C2 (it)
FR (1) FR2463143A1 (it)
GB (1) GB2056449A (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3029871C2 (de) 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält
DK135184A (da) * 1983-03-03 1984-10-10 Riker Laboratories Inc Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner
US4532242A (en) * 1983-05-02 1985-07-30 Riker Laboratories, Inc. Substituted triazolo[4,3-c]pyrimidines
US4528288A (en) * 1983-05-02 1985-07-09 Riker Laboratories, Inc. Substituted triazolo[1,5-c]pyrimidines
US4483987A (en) * 1983-06-20 1984-11-20 G. D. Searle & Co. 8-Substituted 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines and amides
US4866063A (en) * 1988-12-22 1989-09-12 G. D. Searle & Co. Diol metabolites of 7-phenyl-1,2,4-triazolo[2,3-c]pyrimidines-5-amines
US5952331A (en) * 1996-05-23 1999-09-14 Syntex (Usa) Inc. Aryl pyrimidine derivatives
TW440563B (en) * 1996-05-23 2001-06-16 Hoffmann La Roche Aryl pyrimidine derivatives and a pharmaceutical composition thereof
US5958934A (en) * 1996-05-23 1999-09-28 Syntex (U.S.A.) Inc. Aryl pyrimidine derivatives and uses thereof
CN103298794A (zh) 2010-11-09 2013-09-11 塞尔卓姆有限公司 作为tyk2抑制剂的吡啶化合物及其氮杂类似物
CA3135449A1 (en) * 2019-04-03 2020-10-08 Tera Stone Co., Ltd Triazolopyrimidines based on thymine nucleobase and methods for producing them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1205144A (fr) * 1957-06-14 1960-01-29 Farmaceutici Italia Procédé pour la synthèse de 7-méthyl-s. triazol (4, 3-c) pyrimidines substituéesen position 5
US3284542A (en) 1963-03-22 1966-11-08 Rexall Drug Chemical Preparation of high impact compositions from vinyl aromatic monomers and rubbery diolefin polymers
US3244715A (en) 1964-10-30 1966-04-05 Smith Kline French Lab Phenylimidazo [4, 5-d] pyridazines
US3461123A (en) 1968-04-12 1969-08-12 Merck & Co Inc 1h-imidazo(4,5-b)pyrazin-2-ones and processes for their preparation
DE3029871C2 (de) 1979-08-08 1987-01-15 G.D. Searle & Co., Skokie, Ill. 8-(2-Ethoxyethyl)-7-phenyl-1,2,4-triazolo[1,5-c]pyrimidin-5-amin, Verfahren zu dessen Herstellung und pharmazeutische Zubereitung, die diese Verbindung enthält

Also Published As

Publication number Publication date
AU6115380A (en) 1981-02-12
GB2056449A (en) 1981-03-18
CA1246063B (en) 1988-12-06
CA1246064B (en) 1988-12-06
JPH029592B2 (it) 1990-03-02
CA1246064A (en) 1988-12-06
CH645898A5 (de) 1984-10-31
JPS5632479A (en) 1981-04-01
FR2463143A1 (fr) 1981-02-20
CA1246063A (en) 1988-12-06
DE3029871A1 (de) 1981-02-26
AU531507B2 (en) 1983-08-25
DE3029871C2 (de) 1987-01-15

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Legal Events

Date Code Title Description
ST Notification of lapse