FR2461495A1 - Medicament antiparasitaire a effet retard - Google Patents
Medicament antiparasitaire a effet retard Download PDFInfo
- Publication number
- FR2461495A1 FR2461495A1 FR7918935A FR7918935A FR2461495A1 FR 2461495 A1 FR2461495 A1 FR 2461495A1 FR 7918935 A FR7918935 A FR 7918935A FR 7918935 A FR7918935 A FR 7918935A FR 2461495 A1 FR2461495 A1 FR 2461495A1
- Authority
- FR
- France
- Prior art keywords
- sep
- aforementioned
- oblet
- anthelmintic
- anthelmintic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000282849 Ruminantia Species 0.000 title claims abstract description 5
- 241001465754 Metazoa Species 0.000 title abstract description 33
- 230000000507 anthelmentic effect Effects 0.000 title abstract description 11
- 230000002035 prolonged effect Effects 0.000 title abstract description 4
- 230000001988 toxicity Effects 0.000 title abstract description 3
- 231100000419 toxicity Toxicity 0.000 title abstract description 3
- 238000009304 pastoral farming Methods 0.000 title description 5
- 244000000013 helminth Species 0.000 title 1
- 229940124339 anthelmintic agent Drugs 0.000 claims abstract description 20
- 239000000921 anthelmintic agent Substances 0.000 claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 9
- 230000002141 anti-parasite Effects 0.000 claims abstract description 5
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical compound C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 claims description 13
- 229960001614 levamisole Drugs 0.000 claims description 13
- 230000000694 effects Effects 0.000 claims description 8
- 229960005473 fenbendazole Drugs 0.000 claims description 7
- IRHZVMHXVHSMKB-UHFFFAOYSA-N fenbendazole Chemical compound [CH]1C2=NC(NC(=O)OC)=NC2=CC=C1SC1=CC=CC=C1 IRHZVMHXVHSMKB-UHFFFAOYSA-N 0.000 claims description 7
- 241000607479 Yersinia pestis Species 0.000 claims description 6
- 229960002669 albendazole Drugs 0.000 claims description 6
- HXHWSAZORRCQMX-UHFFFAOYSA-N albendazole Chemical compound CCCSC1=CC=C2NC(NC(=O)OC)=NC2=C1 HXHWSAZORRCQMX-UHFFFAOYSA-N 0.000 claims description 6
- 229960004546 thiabendazole Drugs 0.000 claims description 6
- 235000010296 thiabendazole Nutrition 0.000 claims description 6
- 239000004308 thiabendazole Substances 0.000 claims description 6
- 229960003475 cambendazole Drugs 0.000 claims description 5
- BXNANOICGRISHX-UHFFFAOYSA-N coumaphos Chemical compound CC1=C(Cl)C(=O)OC2=CC(OP(=S)(OCC)OCC)=CC=C21 BXNANOICGRISHX-UHFFFAOYSA-N 0.000 claims description 5
- -1 diamphenetbjide Chemical compound 0.000 claims description 5
- QZWHWHNCPFEXLL-UHFFFAOYSA-N propan-2-yl n-[2-(1,3-thiazol-4-yl)-3h-benzimidazol-5-yl]carbamate Chemical compound N1C2=CC(NC(=O)OC(C)C)=CC=C2N=C1C1=CSC=N1 QZWHWHNCPFEXLL-UHFFFAOYSA-N 0.000 claims description 5
- 229960003439 mebendazole Drugs 0.000 claims description 4
- BAXLBXFAUKGCDY-UHFFFAOYSA-N mebendazole Chemical compound [CH]1C2=NC(NC(=O)OC)=NC2=CC=C1C(=O)C1=CC=CC=C1 BAXLBXFAUKGCDY-UHFFFAOYSA-N 0.000 claims description 4
- 229950003126 oxyclozanide Drugs 0.000 claims description 4
- 230000001737 promoting effect Effects 0.000 claims description 4
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 claims description 4
- NVEPPWDVLBMNMB-SNAWJCMRSA-N 1-methyl-2-[(e)-2-(3-methylthiophen-2-yl)ethenyl]-5,6-dihydro-4h-pyrimidine Chemical compound CN1CCCN=C1\C=C\C1=C(C)C=CS1 NVEPPWDVLBMNMB-SNAWJCMRSA-N 0.000 claims description 3
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 claims description 3
- QRBVCAWHUSTDOT-UHFFFAOYSA-N Methyridine Chemical compound COCCC1=CC=CC=N1 QRBVCAWHUSTDOT-UHFFFAOYSA-N 0.000 claims description 3
- YRWLZFXJFBZBEY-UHFFFAOYSA-N N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester Chemical compound CCCCC1=CC=C2N=C(NC(=O)OC)NC2=C1 YRWLZFXJFBZBEY-UHFFFAOYSA-N 0.000 claims description 3
- NRFGEDASJHBPPN-UHFFFAOYSA-N [2-bromo-6-[(4-bromophenyl)carbamothioyl]-4-chlorophenyl] acetate Chemical compound CC(=O)OC1=C(Br)C=C(Cl)C=C1C(=S)NC1=CC=C(Br)C=C1 NRFGEDASJHBPPN-UHFFFAOYSA-N 0.000 claims description 3
- KULDXINYXFTXMO-UHFFFAOYSA-N bis(2-chloroethyl) (3-chloro-4-methyl-2-oxochromen-7-yl) phosphate Chemical compound C1=C(OP(=O)(OCCCl)OCCCl)C=CC2=C1OC(=O)C(Cl)=C2C KULDXINYXFTXMO-UHFFFAOYSA-N 0.000 claims description 3
- JFIOVJDNOJYLKP-UHFFFAOYSA-N bithionol Chemical compound OC1=C(Cl)C=C(Cl)C=C1SC1=CC(Cl)=CC(Cl)=C1O JFIOVJDNOJYLKP-UHFFFAOYSA-N 0.000 claims description 3
- 229960002326 bithionol Drugs 0.000 claims description 3
- 229950005372 brotianide Drugs 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 229950002831 haloxon Drugs 0.000 claims description 3
- 229910052751 metal Inorganic materials 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 229960005121 morantel Drugs 0.000 claims description 3
- XULACPAEUUWKFX-UHFFFAOYSA-N niclofolan Chemical compound C1=C(Cl)C=C([N+]([O-])=O)C(O)=C1C1=CC(Cl)=CC([N+]([O-])=O)=C1O XULACPAEUUWKFX-UHFFFAOYSA-N 0.000 claims description 3
- 229950006977 niclofolan Drugs 0.000 claims description 3
- 229960001920 niclosamide Drugs 0.000 claims description 3
- RJMUSRYZPJIFPJ-UHFFFAOYSA-N niclosamide Chemical compound OC1=CC=C(Cl)C=C1C(=O)NC1=CC=C([N+]([O-])=O)C=C1Cl RJMUSRYZPJIFPJ-UHFFFAOYSA-N 0.000 claims description 3
- JYWIYHUXVMAGLG-UHFFFAOYSA-N oxyclozanide Chemical compound OC1=C(Cl)C=C(Cl)C=C1NC(=O)C1=C(O)C(Cl)=CC(Cl)=C1Cl JYWIYHUXVMAGLG-UHFFFAOYSA-N 0.000 claims description 3
- 229950000688 phenothiazine Drugs 0.000 claims description 3
- 229960005134 pyrantel Drugs 0.000 claims description 3
- YSAUAVHXTIETRK-AATRIKPKSA-N pyrantel Chemical compound CN1CCCN=C1\C=C\C1=CC=CS1 YSAUAVHXTIETRK-AATRIKPKSA-N 0.000 claims description 3
- NEMNPWINWMHUMR-UHFFFAOYSA-N rafoxanide Chemical compound OC1=C(I)C=C(I)C=C1C(=O)NC(C=C1Cl)=CC=C1OC1=CC=C(Cl)C=C1 NEMNPWINWMHUMR-UHFFFAOYSA-N 0.000 claims description 3
- 229950002980 rafoxanide Drugs 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- YFNCATAIYKQPOO-UHFFFAOYSA-N thiophanate Chemical compound CCOC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OCC YFNCATAIYKQPOO-UHFFFAOYSA-N 0.000 claims description 3
- 239000000080 wetting agent Substances 0.000 claims description 3
- RPAJWWXZIQJVJF-UHFFFAOYSA-N 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfinylphenol Chemical compound OC1=C(Cl)C=C(Cl)C=C1S(=O)C1=CC(Cl)=CC(Cl)=C1O RPAJWWXZIQJVJF-UHFFFAOYSA-N 0.000 claims description 2
- RAOCRURYZCVHMG-UHFFFAOYSA-N N-(6-propoxy-1H-benzimidazol-2-yl)carbamic acid methyl ester Chemical compound CCCOC1=CC=C2N=C(NC(=O)OC)NC2=C1 RAOCRURYZCVHMG-UHFFFAOYSA-N 0.000 claims description 2
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 2
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 claims description 2
- 229910000428 cobalt oxide Inorganic materials 0.000 claims description 2
- IVMYJDGYRUAWML-UHFFFAOYSA-N cobalt(ii) oxide Chemical compound [Co]=O IVMYJDGYRUAWML-UHFFFAOYSA-N 0.000 claims description 2
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 2
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 claims description 2
- 229920001249 ethyl cellulose Polymers 0.000 claims description 2
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 2
- UWRBYRMOUPAKLM-UHFFFAOYSA-L lead arsenate Chemical compound [Pb+2].O[As]([O-])([O-])=O UWRBYRMOUPAKLM-UHFFFAOYSA-L 0.000 claims description 2
- GVALZJMUIHGIMD-UHFFFAOYSA-H magnesium phosphate Chemical compound [Mg+2].[Mg+2].[Mg+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GVALZJMUIHGIMD-UHFFFAOYSA-H 0.000 claims description 2
- 239000004137 magnesium phosphate Substances 0.000 claims description 2
- 229960002261 magnesium phosphate Drugs 0.000 claims description 2
- 229910000157 magnesium phosphate Inorganic materials 0.000 claims description 2
- 235000010994 magnesium phosphates Nutrition 0.000 claims description 2
- 229940071125 manganese acetate Drugs 0.000 claims description 2
- UOGMEBQRZBEZQT-UHFFFAOYSA-L manganese(2+);diacetate Chemical compound [Mn+2].CC([O-])=O.CC([O-])=O UOGMEBQRZBEZQT-UHFFFAOYSA-L 0.000 claims description 2
- 229960002762 oxibendazole Drugs 0.000 claims description 2
- 239000012188 paraffin wax Substances 0.000 claims description 2
- 229950007337 parbendazole Drugs 0.000 claims description 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 2
- 229920000915 polyvinyl chloride Polymers 0.000 claims description 2
- 239000004800 polyvinyl chloride Substances 0.000 claims description 2
- 239000000741 silica gel Substances 0.000 claims description 2
- 229910002027 silica gel Inorganic materials 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- LRXTYHSAJDENHV-UHFFFAOYSA-H zinc phosphate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LRXTYHSAJDENHV-UHFFFAOYSA-H 0.000 claims description 2
- 229910000165 zinc phosphate Inorganic materials 0.000 claims description 2
- 229940077935 zinc phosphate Drugs 0.000 claims description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- VJDZMZAZDFKMSV-UHFFFAOYSA-N benzene-1,2-disulfonamide Chemical compound NS(=O)(=O)C1=CC=CC=C1S(N)(=O)=O VJDZMZAZDFKMSV-UHFFFAOYSA-N 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 239000003096 antiparasitic agent Substances 0.000 abstract description 3
- 210000003660 reticulum Anatomy 0.000 abstract 1
- 210000002784 stomach Anatomy 0.000 abstract 1
- 235000013601 eggs Nutrition 0.000 description 45
- 210000003608 fece Anatomy 0.000 description 36
- 238000011282 treatment Methods 0.000 description 25
- 208000004232 Enteritis Diseases 0.000 description 15
- 241000283690 Bos taurus Species 0.000 description 11
- 206010061217 Infestation Diseases 0.000 description 10
- 244000045947 parasite Species 0.000 description 7
- 230000024241 parasitism Effects 0.000 description 7
- 230000001079 digestive effect Effects 0.000 description 6
- 230000001225 therapeutic effect Effects 0.000 description 6
- 241001494479 Pecora Species 0.000 description 5
- 230000036528 appetite Effects 0.000 description 5
- 235000019789 appetite Nutrition 0.000 description 5
- 241000283707 Capra Species 0.000 description 4
- 241000242722 Cestoda Species 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- HMCCXLBXIJMERM-UHFFFAOYSA-N Febantel Chemical compound C1=C(NC(NC(=O)OC)=NC(=O)OC)C(NC(=O)COC)=CC(SC=2C=CC=CC=2)=C1 HMCCXLBXIJMERM-UHFFFAOYSA-N 0.000 description 3
- 208000007502 anemia Diseases 0.000 description 3
- 229960005282 febantel Drugs 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 229960004454 oxfendazole Drugs 0.000 description 3
- BEZZFPOZAYTVHN-UHFFFAOYSA-N oxfendazole Chemical compound C=1C=C2NC(NC(=O)OC)=NC2=CC=1S(=O)C1=CC=CC=C1 BEZZFPOZAYTVHN-UHFFFAOYSA-N 0.000 description 3
- 230000003071 parasitic effect Effects 0.000 description 3
- 244000025254 Cannabis sativa Species 0.000 description 2
- 208000030852 Parasitic disease Diseases 0.000 description 2
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 2
- 210000003165 abomasum Anatomy 0.000 description 2
- 208000031513 cyst Diseases 0.000 description 2
- 229960003974 diethylcarbamazine Drugs 0.000 description 2
- RCKMWOKWVGPNJF-UHFFFAOYSA-N diethylcarbamazine Chemical compound CCN(CC)C(=O)N1CCN(C)CC1 RCKMWOKWVGPNJF-UHFFFAOYSA-N 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 208000006275 fascioliasis Diseases 0.000 description 2
- 244000144980 herd Species 0.000 description 2
- ACGUYXCXAPNIKK-UHFFFAOYSA-N hexachlorophene Chemical compound OC1=C(Cl)C=C(Cl)C(Cl)=C1CC1=C(O)C(Cl)=CC(Cl)=C1Cl ACGUYXCXAPNIKK-UHFFFAOYSA-N 0.000 description 2
- 229960004068 hexachlorophene Drugs 0.000 description 2
- 230000035987 intoxication Effects 0.000 description 2
- 231100000566 intoxication Toxicity 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 230000001418 larval effect Effects 0.000 description 2
- 230000002045 lasting effect Effects 0.000 description 2
- SGKGVABHDAQAJO-UHFFFAOYSA-N nitroxynil Chemical compound OC1=C(I)C=C(C#N)C=C1[N+]([O-])=O SGKGVABHDAQAJO-UHFFFAOYSA-N 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 208000016261 weight loss Diseases 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- DJHGAFSJWGLOIV-UHFFFAOYSA-K Arsenate3- Chemical compound [O-][As]([O-])([O-])=O DJHGAFSJWGLOIV-UHFFFAOYSA-K 0.000 description 1
- 208000031872 Body Remains Diseases 0.000 description 1
- 206010006895 Cachexia Diseases 0.000 description 1
- 241000224483 Coccidia Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- 206010020710 Hyperphagia Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000026681 Paratuberculosis Diseases 0.000 description 1
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 description 1
- 229940000489 arsenate Drugs 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229950004965 bunamidine Drugs 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 125000003963 dichloro group Chemical group Cl* 0.000 description 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000026500 emaciation Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- FGGFIMIICGZCCJ-UHFFFAOYSA-N n,n-dibutyl-4-hexoxynaphthalene-1-carboximidamide Chemical compound C1=CC=C2C(OCCCCCC)=CC=C(C(=N)N(CCCC)CCCC)C2=C1 FGGFIMIICGZCCJ-UHFFFAOYSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 229940100688 oral solution Drugs 0.000 description 1
- 235000020830 overeating Nutrition 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000979 retarding effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 150000003462 sulfoxides Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 206010045458 umbilical hernia Diseases 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0068—Rumen, e.g. rumen bolus
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7918935A FR2461495A1 (fr) | 1979-07-23 | 1979-07-23 | Medicament antiparasitaire a effet retard |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7918935A FR2461495A1 (fr) | 1979-07-23 | 1979-07-23 | Medicament antiparasitaire a effet retard |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2461495A1 true FR2461495A1 (fr) | 1981-02-06 |
| FR2461495B1 FR2461495B1 (OSRAM) | 1983-02-25 |
Family
ID=9228164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7918935A Granted FR2461495A1 (fr) | 1979-07-23 | 1979-07-23 | Medicament antiparasitaire a effet retard |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2461495A1 (OSRAM) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984004677A1 (fr) * | 1983-05-27 | 1984-12-06 | Hoechst Ag | Compositions pharmaceutiques ayant une activite anthelmintique, leurs unites de dosage et procede de traitement de l'helminthiase chez les animaux |
| EP0187012A1 (en) * | 1984-12-22 | 1986-07-09 | Beecham Group Plc | Novel compositions |
| WO1987005504A1 (en) * | 1986-03-15 | 1987-09-24 | Sds Biotech U.K. Limited | Therapeutic compositions for veterinary use |
| EP0279343A3 (en) * | 1987-02-19 | 1989-10-18 | Bayer Ag | Combinations of anthelmintically active agents |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1289423A (fr) * | 1959-01-16 | 1962-04-06 | Wellcome Found | Enrobage en pilule pour l'administration de matières biologiques aux ruminants |
| US3056724A (en) * | 1956-11-05 | 1962-10-02 | Commw Scient Ind Res Org | Therapeutic pellets for ruminants |
| US3507952A (en) * | 1968-12-20 | 1970-04-21 | Smithkline Corp | Sustained release bolus for animal husbandry |
| US3535419A (en) * | 1965-12-15 | 1970-10-20 | Syntex Corp | Veterinary compositions and methods |
| FR2401621A1 (fr) * | 1977-09-02 | 1979-03-30 | Eastman Kodak Co | Granules indegradables dans la panse des ruminants, et procede de preparation de ces granules |
-
1979
- 1979-07-23 FR FR7918935A patent/FR2461495A1/fr active Granted
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3056724A (en) * | 1956-11-05 | 1962-10-02 | Commw Scient Ind Res Org | Therapeutic pellets for ruminants |
| FR1289423A (fr) * | 1959-01-16 | 1962-04-06 | Wellcome Found | Enrobage en pilule pour l'administration de matières biologiques aux ruminants |
| US3535419A (en) * | 1965-12-15 | 1970-10-20 | Syntex Corp | Veterinary compositions and methods |
| US3507952A (en) * | 1968-12-20 | 1970-04-21 | Smithkline Corp | Sustained release bolus for animal husbandry |
| FR2401621A1 (fr) * | 1977-09-02 | 1979-03-30 | Eastman Kodak Co | Granules indegradables dans la panse des ruminants, et procede de preparation de ces granules |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1984004677A1 (fr) * | 1983-05-27 | 1984-12-06 | Hoechst Ag | Compositions pharmaceutiques ayant une activite anthelmintique, leurs unites de dosage et procede de traitement de l'helminthiase chez les animaux |
| EP0187012A1 (en) * | 1984-12-22 | 1986-07-09 | Beecham Group Plc | Novel compositions |
| WO1987005504A1 (en) * | 1986-03-15 | 1987-09-24 | Sds Biotech U.K. Limited | Therapeutic compositions for veterinary use |
| EP0240169A1 (en) * | 1986-03-15 | 1987-10-07 | Fermenta Asc Europe Limited | The preparation of therapeutic compositions for veterinary use |
| EP0279343A3 (en) * | 1987-02-19 | 1989-10-18 | Bayer Ag | Combinations of anthelmintically active agents |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2461495B1 (OSRAM) | 1983-02-25 |
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