FR2455037A1 - Methoxy tryptamine succinic amide - having melatonin activity, but administrable parenterally - Google Patents

Methoxy tryptamine succinic amide - having melatonin activity, but administrable parenterally

Info

Publication number
FR2455037A1
FR2455037A1 FR7911387A FR7911387A FR2455037A1 FR 2455037 A1 FR2455037 A1 FR 2455037A1 FR 7911387 A FR7911387 A FR 7911387A FR 7911387 A FR7911387 A FR 7911387A FR 2455037 A1 FR2455037 A1 FR 2455037A1
Authority
FR
France
Prior art keywords
parenterally
melatonin
succinic amide
methoxy tryptamine
melatonin activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7911387A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7911387A priority Critical patent/FR2455037A1/en
Publication of FR2455037A1 publication Critical patent/FR2455037A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)

Abstract

The succinic amide of methoxy tryptamine (I) and its salts, are new (I) acts in the same way as melatonin, being a hypophysisary block. (I) is dissolved in water buffered with sodium bicarbonate at pH 7, warming to 40-50 deg.C. In animal tests the dosage was 2 mg per rat per day, and in a clinical trial the dosage was 6 mg per kg, given parenterally. Unlike melatonin itself (I) is water soluble and is therefore very effective parenterally.
FR7911387A 1979-04-27 1979-04-27 Methoxy tryptamine succinic amide - having melatonin activity, but administrable parenterally Withdrawn FR2455037A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7911387A FR2455037A1 (en) 1979-04-27 1979-04-27 Methoxy tryptamine succinic amide - having melatonin activity, but administrable parenterally

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7911387A FR2455037A1 (en) 1979-04-27 1979-04-27 Methoxy tryptamine succinic amide - having melatonin activity, but administrable parenterally

Publications (1)

Publication Number Publication Date
FR2455037A1 true FR2455037A1 (en) 1980-11-21

Family

ID=9225091

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7911387A Withdrawn FR2455037A1 (en) 1979-04-27 1979-04-27 Methoxy tryptamine succinic amide - having melatonin activity, but administrable parenterally

Country Status (1)

Country Link
FR (1) FR2455037A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2385718A1 (en) * 1977-03-28 1978-10-27 Richter Gedeon Vegyeszet Cerebral vasodilatory apovincaminic acid ester prepn. - by synthesis from tryptamine derivs. via novel intermediates and novel 16-alkyl derivs.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2385718A1 (en) * 1977-03-28 1978-10-27 Richter Gedeon Vegyeszet Cerebral vasodilatory apovincaminic acid ester prepn. - by synthesis from tryptamine derivs. via novel intermediates and novel 16-alkyl derivs.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/60 *

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Legal Events

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