FR2117955A1 - N-(3, 4-dihydroxy-beta-phenethyl) amides of amino-acids - - which are renal vasodilators and hypertensives - Google Patents

N-(3, 4-dihydroxy-beta-phenethyl) amides of amino-acids - - which are renal vasodilators and hypertensives

Info

Publication number
FR2117955A1
FR2117955A1 FR7144101A FR7144101A FR2117955A1 FR 2117955 A1 FR2117955 A1 FR 2117955A1 FR 7144101 A FR7144101 A FR 7144101A FR 7144101 A FR7144101 A FR 7144101A FR 2117955 A1 FR2117955 A1 FR 2117955A1
Authority
FR
France
Prior art keywords
amides
beta
hypertensives
phenethyl
dihydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7144101A
Other languages
French (fr)
Other versions
FR2117955B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aldrich Chemical Co Inc
Original Assignee
Aldrich Chemical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aldrich Chemical Co Inc filed Critical Aldrich Chemical Co Inc
Publication of FR2117955A1 publication Critical patent/FR2117955A1/en
Application granted granted Critical
Publication of FR2117955B1 publication Critical patent/FR2117955B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title amides of formula (I): (where R is H, lower alkyl, hydroxymethyl, hydroxybenzyl, 2-hydroxyethyl, mercaptomethyl, methylmercaptoethyl, 3-indolylmethyl, 2-carboxyethyl, 3-guanidinopropyl, 4-aminobutyl or 5-imidazolylmentyl) and their acceptable acid addition salts, which can be used for treating renal hypertension and shock, may be prepd. by reacting 3,4-dibenzyloxy-beta-phenethylamine with HOOC-CHR-NH-COOCH2C6H5 and hydrogenating the resulting N-carbobenzoxy cpd. in the presence of methanol and acid.
FR7144101A 1970-12-09 1971-12-08 N-(3, 4-dihydroxy-beta-phenethyl) amides of amino-acids - - which are renal vasodilators and hypertensives Granted FR2117955A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9661770A 1970-12-09 1970-12-09
US9661570A 1970-12-09 1970-12-09

Publications (2)

Publication Number Publication Date
FR2117955A1 true FR2117955A1 (en) 1972-07-28
FR2117955B1 FR2117955B1 (en) 1975-02-07

Family

ID=26791883

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7144101A Granted FR2117955A1 (en) 1970-12-09 1971-12-08 N-(3, 4-dihydroxy-beta-phenethyl) amides of amino-acids - - which are renal vasodilators and hypertensives

Country Status (1)

Country Link
FR (1) FR2117955A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2001650A1 (en) * 1968-02-09 1969-09-26 Searle & Co

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2001650A1 (en) * 1968-02-09 1969-09-26 Searle & Co

Also Published As

Publication number Publication date
FR2117955B1 (en) 1975-02-07

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Legal Events

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