FR2452497A1 - Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques - Google Patents

Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques

Info

Publication number
FR2452497A1
FR2452497A1 FR8006888A FR8006888A FR2452497A1 FR 2452497 A1 FR2452497 A1 FR 2452497A1 FR 8006888 A FR8006888 A FR 8006888A FR 8006888 A FR8006888 A FR 8006888A FR 2452497 A1 FR2452497 A1 FR 2452497A1
Authority
FR
France
Prior art keywords
fortimicin
synthesis
application
antibiotics
demethylfortimicineb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8006888A
Other languages
English (en)
French (fr)
Other versions
FR2452497B1 (Direct
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of FR2452497A1 publication Critical patent/FR2452497A1/fr
Application granted granted Critical
Publication of FR2452497B1 publication Critical patent/FR2452497B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8006888A 1979-03-29 1980-03-27 Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques Granted FR2452497A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/025,250 US4219643A (en) 1979-03-29 1979-03-29 Fortimicin AN

Publications (2)

Publication Number Publication Date
FR2452497A1 true FR2452497A1 (fr) 1980-10-24
FR2452497B1 FR2452497B1 (Direct) 1983-06-03

Family

ID=21824938

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8006888A Granted FR2452497A1 (fr) 1979-03-29 1980-03-27 Fortimicine an et son application comme intermediaire dans la synthese d'antibiotiques

Country Status (11)

Country Link
US (1) US4219643A (Direct)
JP (1) JPS55130997A (Direct)
AR (1) AR224399A1 (Direct)
AU (1) AU5628080A (Direct)
BE (1) BE882509A (Direct)
CA (1) CA1151090A (Direct)
DE (1) DE3012208A1 (Direct)
ES (1) ES490012A0 (Direct)
FR (1) FR2452497A1 (Direct)
GB (1) GB2047688B (Direct)
GR (1) GR67284B (Direct)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2226159A1 (Direct) * 1973-04-17 1974-11-15 Kyowa Hakko Kogyo Kk
FR2238502A1 (Direct) * 1973-07-23 1975-02-21 Kyowa Hakko Kogyo Kk
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
FR2375250A1 (fr) * 1976-12-27 1978-07-21 Abbott Lab 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878193A (en) * 1973-06-26 1975-04-15 Schering Corp Process for the preparation of garamine derivatives
US3963695A (en) * 1974-12-19 1976-06-15 Smithkline Corporation Tetradeoxyneamine and derivatives thereof
US4091032A (en) * 1976-09-23 1978-05-23 Abbott Laboratories 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2226159A1 (Direct) * 1973-04-17 1974-11-15 Kyowa Hakko Kogyo Kk
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
FR2238502A1 (Direct) * 1973-07-23 1975-02-21 Kyowa Hakko Kogyo Kk
US3976768A (en) * 1973-07-23 1976-08-24 Abbott Laboratories Fortimicin A
FR2375250A1 (fr) * 1976-12-27 1978-07-21 Abbott Lab 3-de-0-methylfortimicines, leur procede de preparation et leur utilisation therapeutique comme antibiotiques
US4124756A (en) * 1976-12-27 1978-11-07 Abbott Laboratories 3-DE-O-Methylfortimicins

Also Published As

Publication number Publication date
ES8104410A1 (es) 1981-04-01
JPS55130997A (en) 1980-10-11
US4219643A (en) 1980-08-26
FR2452497B1 (Direct) 1983-06-03
BE882509A (fr) 1980-09-29
AR224399A1 (es) 1981-11-30
ES490012A0 (es) 1981-04-01
GB2047688A (en) 1980-12-03
CA1151090A (en) 1983-08-02
GR67284B (Direct) 1981-06-29
GB2047688B (en) 1983-03-30
AU5628080A (en) 1980-10-02
DE3012208A1 (de) 1980-10-09

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Legal Events

Date Code Title Description
ST Notification of lapse