ES8104410A1 - Un metodo de produccion de 3-o-desmetil-fortimicina b a par-tir de fortimicina an - Google Patents

Un metodo de produccion de 3-o-desmetil-fortimicina b a par-tir de fortimicina an

Info

Publication number
ES8104410A1
ES8104410A1 ES490012A ES490012A ES8104410A1 ES 8104410 A1 ES8104410 A1 ES 8104410A1 ES 490012 A ES490012 A ES 490012A ES 490012 A ES490012 A ES 490012A ES 8104410 A1 ES8104410 A1 ES 8104410A1
Authority
ES
Spain
Prior art keywords
fortimicin
demethylfortimicin
coproduced
glycyl
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490012A
Other languages
English (en)
Other versions
ES490012A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES490012A0 publication Critical patent/ES490012A0/es
Publication of ES8104410A1 publication Critical patent/ES8104410A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/48—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being substituted by two or more nitrogen atoms, e.g. destomycin, neamin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO DE PRODUCCION DE 3-0-DESMETIL-FORTIMICINA B, A PARTIR DE FORTIMICINA AN. SE PARTE DE LA FORTIMICINA AN, DE FORMULA (I), LA CUAL SE SOMETE A HIDROLISI EN PRESENCIA DE UNA BASE Y POSTERIORMENTE SE RECUPERA DE LA MEZCLA DE REACCION DE 3-0-DESMETILFORTIMICINA B. ESTE COMPUESTO TIENE APLICACION COMO ANTIBIOTICO. *FORMULA* L
ES490012A 1979-03-29 1980-03-27 Un metodo de produccion de 3-o-desmetil-fortimicina b a par-tir de fortimicina an Expired ES8104410A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/025,250 US4219643A (en) 1979-03-29 1979-03-29 Fortimicin AN

Publications (2)

Publication Number Publication Date
ES490012A0 ES490012A0 (es) 1981-04-01
ES8104410A1 true ES8104410A1 (es) 1981-04-01

Family

ID=21824938

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490012A Expired ES8104410A1 (es) 1979-03-29 1980-03-27 Un metodo de produccion de 3-o-desmetil-fortimicina b a par-tir de fortimicina an

Country Status (11)

Country Link
US (1) US4219643A (es)
JP (1) JPS55130997A (es)
AR (1) AR224399A1 (es)
AU (1) AU5628080A (es)
BE (1) BE882509A (es)
CA (1) CA1151090A (es)
DE (1) DE3012208A1 (es)
ES (1) ES8104410A1 (es)
FR (1) FR2452497A1 (es)
GB (1) GB2047688B (es)
GR (1) GR67284B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
JPS5246311B2 (es) * 1973-04-17 1977-11-24
JPS5145675B2 (es) * 1973-07-23 1976-12-04
US3878193A (en) * 1973-06-26 1975-04-15 Schering Corp Process for the preparation of garamine derivatives
US3963695A (en) * 1974-12-19 1976-06-15 Smithkline Corporation Tetradeoxyneamine and derivatives thereof
US4091032A (en) * 1976-09-23 1978-05-23 Abbott Laboratories 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
US4124756A (en) * 1976-12-27 1978-11-07 Abbott Laboratories 3-DE-O-Methylfortimicins

Also Published As

Publication number Publication date
AR224399A1 (es) 1981-11-30
FR2452497B1 (es) 1983-06-03
US4219643A (en) 1980-08-26
ES490012A0 (es) 1981-04-01
GB2047688B (en) 1983-03-30
FR2452497A1 (fr) 1980-10-24
GB2047688A (en) 1980-12-03
AU5628080A (en) 1980-10-02
JPS55130997A (en) 1980-10-11
CA1151090A (en) 1983-08-02
GR67284B (es) 1981-06-29
BE882509A (fr) 1980-09-29
DE3012208A1 (de) 1980-10-09

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990601