FR2449088A1 - Nouveaux derives du benzodioxanne portant en position 5 du noyau benzodioxanne un enchainement n-arylpiperazinopropyl (ou hydroxy-2 propyl) oxy, leurs procedes de preparation et leur application en therapeutique - Google Patents
Nouveaux derives du benzodioxanne portant en position 5 du noyau benzodioxanne un enchainement n-arylpiperazinopropyl (ou hydroxy-2 propyl) oxy, leurs procedes de preparation et leur application en therapeutiqueInfo
- Publication number
- FR2449088A1 FR2449088A1 FR7903745A FR7903745A FR2449088A1 FR 2449088 A1 FR2449088 A1 FR 2449088A1 FR 7903745 A FR7903745 A FR 7903745A FR 7903745 A FR7903745 A FR 7903745A FR 2449088 A1 FR2449088 A1 FR 2449088A1
- Authority
- FR
- France
- Prior art keywords
- derivs
- hypotensives
- benzodioxan
- vasodilators
- piperazinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KREUEDZLJDPRHW-UHFFFAOYSA-N 1-(2-propoxy-2,3-dihydro-1,4-benzodioxin-5-yl)piperazine Chemical compound N1(CCNCC1)C1=CC=CC=2OC(COC=21)OCCC KREUEDZLJDPRHW-UHFFFAOYSA-N 0.000 title 1
- 208000001953 Hypotension Diseases 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
- 229940124549 vasodilator Drugs 0.000 title 1
- 239000003071 vasodilator agent Substances 0.000 title 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000004458 methylaminocarbonyl group Chemical group [H]N(C(*)=O)C([H])([H])[H] 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000000213 tachycardiac effect Effects 0.000 abstract 1
- 231100001274 therapeutic index Toxicity 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7903745A FR2449088A1 (fr) | 1979-02-14 | 1979-02-14 | Nouveaux derives du benzodioxanne portant en position 5 du noyau benzodioxanne un enchainement n-arylpiperazinopropyl (ou hydroxy-2 propyl) oxy, leurs procedes de preparation et leur application en therapeutique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7903745A FR2449088A1 (fr) | 1979-02-14 | 1979-02-14 | Nouveaux derives du benzodioxanne portant en position 5 du noyau benzodioxanne un enchainement n-arylpiperazinopropyl (ou hydroxy-2 propyl) oxy, leurs procedes de preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2449088A1 true FR2449088A1 (fr) | 1980-09-12 |
| FR2449088B1 FR2449088B1 (enrdf_load_stackoverflow) | 1982-03-26 |
Family
ID=9221960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7903745A Granted FR2449088A1 (fr) | 1979-02-14 | 1979-02-14 | Nouveaux derives du benzodioxanne portant en position 5 du noyau benzodioxanne un enchainement n-arylpiperazinopropyl (ou hydroxy-2 propyl) oxy, leurs procedes de preparation et leur application en therapeutique |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2449088A1 (enrdf_load_stackoverflow) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0156331A3 (en) * | 1984-03-27 | 1986-08-20 | Kaken Pharmaceutical Co., Ltd. | Benzuforan derivatives, processes for preparing the same and antihypertensive agents containing the same |
| EP0943613A4 (en) * | 1996-11-19 | 2002-07-10 | Kyowa Hakko Kogyo Kk | Oxygenic heterocyclic compounds |
| US6514996B2 (en) | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2330390A2 (fr) * | 1975-11-05 | 1977-06-03 | Delalande Sa | Nouvelles benzodioxanes-1,4, leur procede de preparation et leur application en therapeutique |
-
1979
- 1979-02-14 FR FR7903745A patent/FR2449088A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2330390A2 (fr) * | 1975-11-05 | 1977-06-03 | Delalande Sa | Nouvelles benzodioxanes-1,4, leur procede de preparation et leur application en therapeutique |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0156331A3 (en) * | 1984-03-27 | 1986-08-20 | Kaken Pharmaceutical Co., Ltd. | Benzuforan derivatives, processes for preparing the same and antihypertensive agents containing the same |
| US6514996B2 (en) | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
| US6716987B1 (en) | 1995-05-19 | 2004-04-06 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxazole compounds |
| EP0943613A4 (en) * | 1996-11-19 | 2002-07-10 | Kyowa Hakko Kogyo Kk | Oxygenic heterocyclic compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2449088B1 (enrdf_load_stackoverflow) | 1982-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |