ES478983A1 - Procedimiento para la estabilizacion de nicotinamidoadenin- dinucleotidos. - Google Patents
Procedimiento para la estabilizacion de nicotinamidoadenin- dinucleotidos.Info
- Publication number
- ES478983A1 ES478983A1 ES478983A ES478983A ES478983A1 ES 478983 A1 ES478983 A1 ES 478983A1 ES 478983 A ES478983 A ES 478983A ES 478983 A ES478983 A ES 478983A ES 478983 A1 ES478983 A1 ES 478983A1
- Authority
- ES
- Spain
- Prior art keywords
- adenine
- stabilizator
- dinucleotides
- preparation
- nicotinamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 229950006238 nadide Drugs 0.000 abstract 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
1. Procedimiento para la estabilización de nicotinamido-adenin-dinucleótidos, caracterizado porque se mezcla una solución del nucleótido con un colágeno hidrolíticamente degradado, eventualmente recitulado, en la proporción de 1:0,001 a 1:1200, se ajusta el pH a un valor comprendido entre 5 y 11, y se saca la solución, preferiblemente por litofilización.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19782814154 DE2814154A1 (de) | 1978-04-01 | 1978-04-01 | Stabilisierte nicotinamid-nucleotide und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES478983A1 true ES478983A1 (es) | 1980-06-16 |
Family
ID=6035958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478983A Expired ES478983A1 (es) | 1978-04-01 | 1979-03-27 | Procedimiento para la estabilizacion de nicotinamidoadenin- dinucleotidos. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4219645A (es) |
| EP (1) | EP0004639B1 (es) |
| JP (1) | JPS54138596A (es) |
| AT (1) | AT365344B (es) |
| AU (1) | AU530670B2 (es) |
| CA (1) | CA1125747A (es) |
| DE (2) | DE2814154A1 (es) |
| DK (1) | DK132279A (es) |
| ES (1) | ES478983A1 (es) |
| IL (1) | IL56981A0 (es) |
| NZ (1) | NZ190048A (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4587044A (en) * | 1983-09-01 | 1986-05-06 | The Johns Hopkins University | Linkage of proteins to nucleic acids |
| WO2006038647A1 (ja) * | 2004-10-05 | 2006-04-13 | Asahi Kasei Pharma Corporation | 補酵素の安定化方法およびその組成物 |
| CN118591635A (zh) * | 2022-01-28 | 2024-09-03 | 东方酵母工业株式会社 | 烟酰胺腺嘌呤二核苷酸的稳定化方法和稳定化用组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1118792B (de) * | 1958-01-22 | 1961-12-07 | Hoechst Ag | Verfahren zur Herstellung von Blutplasmaersatzmitteln aus Kollagenabbauprodukten |
| DE1155134B (de) * | 1958-06-07 | 1963-10-03 | Hoechst Ag | Verfahren zur Herstellung von Blutplasmaersatzmitteln aus Kollagenabbauprodukten |
| DE1930059C3 (de) | 1969-06-13 | 1975-11-13 | Boehringer Mannheim Gmbh | Stabilisiertes Nicotinamid-adenindinucleotid oder bzw. und Nicotinamld-adenin-dinucleotidphosphat |
| DE2050267C3 (de) * | 1970-10-13 | 1974-06-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur Herstellung von stabilen Zubereitungen von reduziertem Nicotinamidadenindinucleotid |
| US3776900A (en) * | 1971-04-26 | 1973-12-04 | Searle & Co | Stabilization of reduced coenzymes |
| CA1102225A (en) * | 1976-09-13 | 1981-06-02 | Ivan E. Modrovich | Stabilized liquid enzyme and coenzyme compositions and method of preparing same |
-
1978
- 1978-04-01 DE DE19782814154 patent/DE2814154A1/de not_active Withdrawn
-
1979
- 1979-03-27 ES ES478983A patent/ES478983A1/es not_active Expired
- 1979-03-29 EP EP79100940A patent/EP0004639B1/de not_active Expired
- 1979-03-29 US US06/025,052 patent/US4219645A/en not_active Expired - Lifetime
- 1979-03-29 DE DE7979100940T patent/DE2962084D1/de not_active Expired
- 1979-03-30 AT AT0237579A patent/AT365344B/de not_active IP Right Cessation
- 1979-03-30 AU AU45649/79A patent/AU530670B2/en not_active Ceased
- 1979-03-30 JP JP3828979A patent/JPS54138596A/ja active Granted
- 1979-03-30 DK DK132279A patent/DK132279A/da unknown
- 1979-03-30 IL IL56981A patent/IL56981A0/xx unknown
- 1979-03-30 NZ NZ190048A patent/NZ190048A/xx unknown
- 1979-03-30 CA CA324,529A patent/CA1125747A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU530670B2 (en) | 1983-07-28 |
| AU4564979A (en) | 1981-05-14 |
| DE2814154A1 (de) | 1979-10-11 |
| NZ190048A (en) | 1981-05-29 |
| EP0004639A2 (de) | 1979-10-17 |
| AT365344B (de) | 1982-01-11 |
| US4219645A (en) | 1980-08-26 |
| ATA237579A (de) | 1981-05-15 |
| DE2962084D1 (en) | 1982-03-18 |
| EP0004639A3 (en) | 1979-10-31 |
| IL56981A0 (en) | 1979-05-31 |
| DK132279A (da) | 1979-10-02 |
| EP0004639B1 (de) | 1982-02-10 |
| CA1125747A (en) | 1982-06-15 |
| JPH0130839B2 (es) | 1989-06-22 |
| JPS54138596A (en) | 1979-10-27 |
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