FR2445719A1 - Renal calculus treatment with sequestrant - comprising (co)polymer of unsatd. carboxylic acid - Google Patents

Renal calculus treatment with sequestrant - comprising (co)polymer of unsatd. carboxylic acid

Info

Publication number
FR2445719A1
FR2445719A1 FR7900253A FR7900253A FR2445719A1 FR 2445719 A1 FR2445719 A1 FR 2445719A1 FR 7900253 A FR7900253 A FR 7900253A FR 7900253 A FR7900253 A FR 7900253A FR 2445719 A1 FR2445719 A1 FR 2445719A1
Authority
FR
France
Prior art keywords
pref
polymer
treatment
unsatd
renal calculus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7900253A
Other languages
French (fr)
Other versions
FR2445719B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warren-Teed Laboratories Inc
Original Assignee
Warren-Teed Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warren-Teed Laboratories Inc filed Critical Warren-Teed Laboratories Inc
Priority to FR7900253A priority Critical patent/FR2445719A1/en
Publication of FR2445719A1 publication Critical patent/FR2445719A1/en
Application granted granted Critical
Publication of FR2445719B1 publication Critical patent/FR2445719B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen

Abstract

Treatment of renal calculus comprises administering a (co)polymer (I) derived from an olefinically unsatd. mono- or polycarboxylic acid (II). If (I) is water-soluble, it has mol. wt. >10000, and if it forms colloidal aq. solns. it has swelling index >=10 (pref. 10-500). Unit dose compsns. contain 0.1-20 g of (I), opt. in slat form. Pref. (II) include acrylic, (m)ethacrylic, alpha-chloroacrylic, +-cyanoacrylic, crotonic, beta-acryloxypropionic, hydrosorbic, sorbic, alpha-chlorosorbic, cinnamic, beta-styrylacrylic, hydromuconic, itaconic, citraconic, mesaconic, muconic, glutaconic and aconitic acids. (I) dissolve calculi and bond calcium so that it is excreted in faeces rather than urine. They are effective in treatment of urolithiasis in lower doses than phosphates, and are easily dosed since they can be administered in liquid form. Daily dose is pref. 10-400 mg/kg p.o.
FR7900253A 1979-01-05 1979-01-05 Renal calculus treatment with sequestrant - comprising (co)polymer of unsatd. carboxylic acid Granted FR2445719A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7900253A FR2445719A1 (en) 1979-01-05 1979-01-05 Renal calculus treatment with sequestrant - comprising (co)polymer of unsatd. carboxylic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7900253A FR2445719A1 (en) 1979-01-05 1979-01-05 Renal calculus treatment with sequestrant - comprising (co)polymer of unsatd. carboxylic acid

Publications (2)

Publication Number Publication Date
FR2445719A1 true FR2445719A1 (en) 1980-08-01
FR2445719B1 FR2445719B1 (en) 1985-04-12

Family

ID=9220496

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7900253A Granted FR2445719A1 (en) 1979-01-05 1979-01-05 Renal calculus treatment with sequestrant - comprising (co)polymer of unsatd. carboxylic acid

Country Status (1)

Country Link
FR (1) FR2445719A1 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962420A (en) * 1974-07-03 1976-06-08 Rohm And Haas Company Dissolution of gallstones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3962420A (en) * 1974-07-03 1976-06-08 Rohm And Haas Company Dissolution of gallstones

Also Published As

Publication number Publication date
FR2445719B1 (en) 1985-04-12

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