FR2445331A1 - PTERIDINE COMPOUNDS AND THEIR APPLICATION AS THERAPEUTICALLY ACTIVE MATERIALS IN PHARMACEUTICAL PREPARATIONS - Google Patents

PTERIDINE COMPOUNDS AND THEIR APPLICATION AS THERAPEUTICALLY ACTIVE MATERIALS IN PHARMACEUTICAL PREPARATIONS

Info

Publication number
FR2445331A1
FR2445331A1 FR8003308A FR8003308A FR2445331A1 FR 2445331 A1 FR2445331 A1 FR 2445331A1 FR 8003308 A FR8003308 A FR 8003308A FR 8003308 A FR8003308 A FR 8003308A FR 2445331 A1 FR2445331 A1 FR 2445331A1
Authority
FR
France
Prior art keywords
pharmaceutical preparations
application
active materials
therapeutically active
pteridine compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8003308A
Other languages
French (fr)
Other versions
FR2445331B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roehm Pharma GmbH
Original Assignee
Roehm Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roehm Pharma GmbH filed Critical Roehm Pharma GmbH
Publication of FR2445331A1 publication Critical patent/FR2445331A1/en
Application granted granted Critical
Publication of FR2445331B1 publication Critical patent/FR2445331B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

Ces composés répondent à la formule IB ci-après, dans laquelle R' est un groupe hydrophile, notamment un groupe acétyle, méthyle, hydroxyéthyle, dihydroxypropyle. Les préparations pharmaceutiques considérées ont une action diurétique, antihypertensive et cardiaque et permettent de traiter les oedèmes et les maladies du coeur et de coronaires.These compounds correspond to formula IB below, in which R ′ is a hydrophilic group, in particular an acetyl, methyl, hydroxyethyl or dihydroxypropyl group. The pharmaceutical preparations considered have a diuretic, antihypertensive and cardiac action and make it possible to treat edemas and heart and coronary diseases.

FR8003308A 1977-01-03 1980-02-14 PTERIDINE COMPOUNDS AND THEIR APPLICATION AS THERAPEUTICALLY ACTIVE MATERIALS IN PHARMACEUTICAL PREPARATIONS Granted FR2445331A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772700073 DE2700073A1 (en) 1977-01-03 1977-01-03 PTERIDINE COMPOUNDS WITH PHARMACEUTICAL EFFECTIVENESS

Publications (2)

Publication Number Publication Date
FR2445331A1 true FR2445331A1 (en) 1980-07-25
FR2445331B1 FR2445331B1 (en) 1983-01-28

Family

ID=5998070

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7739798A Expired FR2420345B1 (en) 1977-01-03 1977-12-30
FR8003308A Granted FR2445331A1 (en) 1977-01-03 1980-02-14 PTERIDINE COMPOUNDS AND THEIR APPLICATION AS THERAPEUTICALLY ACTIVE MATERIALS IN PHARMACEUTICAL PREPARATIONS

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7739798A Expired FR2420345B1 (en) 1977-01-03 1977-12-30

Country Status (13)

Country Link
JP (1) JPS5384993A (en)
AT (1) AT353798B (en)
AU (1) AU515140B2 (en)
CA (1) CA1099714A (en)
CH (2) CH633962A5 (en)
DD (1) DD136837A5 (en)
DE (1) DE2700073A1 (en)
ES (1) ES465578A1 (en)
FR (2) FR2420345B1 (en)
GB (2) GB1597881A (en)
NL (1) NL190573C (en)
SE (1) SE436203B (en)
ZA (1) ZA7812B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815442A1 (en) * 1978-04-10 1979-10-18 Roehm Pharma Gmbh QUICKLY EFFECTIVE DIURETICS
DE3407695A1 (en) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt PTERIDINE COMPOUNDS WITH PHARMACEUTICAL EFFECTIVENESS
DE3505253C2 (en) * 1985-02-15 1995-04-27 Seitz Enzinger Noll Masch Bottle distribution station for converting a conveyed single-track bottle flow into a wide bottle flow to be removed
HU214331B (en) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Methods for producing piperazine and homopiperazine derivatives and pharmaceutical compositions containing them
WO2023052239A1 (en) 2021-09-28 2023-04-06 Ambu A/S An endoscope

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1014M (en) * 1960-11-05 1961-12-26 Smith Kline French Lab Medicinal compositions based on 6-aryl-2,4,7-triaminopteridine.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081230A (en) 1960-09-08 1963-03-12 Smith Kline French Lab Diuretic and antihypertensive triaminoarylpteridines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1014M (en) * 1960-11-05 1961-12-26 Smith Kline French Lab Medicinal compositions based on 6-aryl-2,4,7-triaminopteridine.

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CA1966 *
EXBK/54 *
EXBK/65 *
EXBK/67 *
EXBK/68 *

Also Published As

Publication number Publication date
FR2420345B1 (en) 1983-01-28
DD136837A5 (en) 1979-08-01
DE2700073A1 (en) 1978-07-13
NL7800067A (en) 1978-07-05
AT353798B (en) 1979-12-10
FR2445331B1 (en) 1983-01-28
GB1597881A (en) 1981-09-16
SE7800048L (en) 1978-07-04
CH633962A5 (en) 1983-01-14
JPS631314B2 (en) 1988-01-12
NL190573B (en) 1993-12-01
DE2700073C2 (en) 1991-03-21
JPS5384993A (en) 1978-07-26
CH639663A5 (en) 1983-11-30
CA1099714A (en) 1981-04-21
ATA748877A (en) 1979-05-15
FR2420345A1 (en) 1979-10-19
SE436203B (en) 1984-11-19
NL190573C (en) 1994-05-02
ES465578A1 (en) 1979-01-01
AU515140B2 (en) 1981-03-19
AU3214078A (en) 1979-07-12
GB1597882A (en) 1981-09-16
ZA7812B (en) 1978-10-25

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