FR2438481A1 - Antiinflammatory, antidepressant and eutrophic compsns. - contg. polar lipid, lipolytic enzyme, vitamin=E or synthetic antioxidant and selenium cpd. - Google Patents

Antiinflammatory, antidepressant and eutrophic compsns. - contg. polar lipid, lipolytic enzyme, vitamin=E or synthetic antioxidant and selenium cpd.

Info

Publication number
FR2438481A1
FR2438481A1 FR7829073A FR7829073A FR2438481A1 FR 2438481 A1 FR2438481 A1 FR 2438481A1 FR 7829073 A FR7829073 A FR 7829073A FR 7829073 A FR7829073 A FR 7829073A FR 2438481 A1 FR2438481 A1 FR 2438481A1
Authority
FR
France
Prior art keywords
compsns
cpd
selenium
vitamin
antidepressant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7829073A
Other languages
French (fr)
Other versions
FR2438481B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7829073A priority Critical patent/FR2438481A1/en
Priority to BE191150A priority patent/BE871298A/en
Publication of FR2438481A1 publication Critical patent/FR2438481A1/en
Application granted granted Critical
Publication of FR2438481B1 publication Critical patent/FR2438481B1/fr
Priority to FR8705813A priority patent/FR2614205A2/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01013—Sterol esterase (3.1.1.13)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01004—Phospholipase A2 (3.1.1.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pharmaceutical compsns. containing vitamin E or a synthetic antioxidant, a selenium cpd. one or more lipolytic enzymes with an affinity for a water-lipid interface and polar lipids. Antiinflammatory, antidepressant and entrophic effects, also has hepatrophic, antiatheromatous and vasculotropic effects. Pref. compsns. contain 20-30 mg/g of vitamin E and 0.4 mg/g of selenium cpd. Compsns. of the polar lipids and enzymes are sufficiently stable to be freeze-dried. The compsns. may contain non-polar lipids such as neutral triglycerides, cholesterol and its long-chain alkanoic acid esters. Globin and/or phytol may also be included.
FR7829073A 1978-10-11 1978-10-11 Antiinflammatory, antidepressant and eutrophic compsns. - contg. polar lipid, lipolytic enzyme, vitamin=E or synthetic antioxidant and selenium cpd. Granted FR2438481A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7829073A FR2438481A1 (en) 1978-10-11 1978-10-11 Antiinflammatory, antidepressant and eutrophic compsns. - contg. polar lipid, lipolytic enzyme, vitamin=E or synthetic antioxidant and selenium cpd.
BE191150A BE871298A (en) 1978-10-11 1978-10-16 LIPOPROTEIC COMPLEX NORMALIZING THE EFFECTIVENESS OF VITAMIN E AND SYNTHETIC ANTIOXIDANTS
FR8705813A FR2614205A2 (en) 1978-10-11 1987-04-24 Lipoprotein complex normalising the efficacy of vitamin E and of synthetic antioxidants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7829073A FR2438481A1 (en) 1978-10-11 1978-10-11 Antiinflammatory, antidepressant and eutrophic compsns. - contg. polar lipid, lipolytic enzyme, vitamin=E or synthetic antioxidant and selenium cpd.

Publications (2)

Publication Number Publication Date
FR2438481A1 true FR2438481A1 (en) 1980-05-09
FR2438481B1 FR2438481B1 (en) 1981-05-29

Family

ID=9213628

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7829073A Granted FR2438481A1 (en) 1978-10-11 1978-10-11 Antiinflammatory, antidepressant and eutrophic compsns. - contg. polar lipid, lipolytic enzyme, vitamin=E or synthetic antioxidant and selenium cpd.

Country Status (2)

Country Link
BE (1) BE871298A (en)
FR (1) FR2438481A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0243446A1 (en) * 1985-10-15 1987-11-04 Liposome Co Inc Alpha tocopherol-based vesicles.
FR2614205A2 (en) * 1978-10-11 1988-10-28 Bugard Pierre Lipoprotein complex normalising the efficacy of vitamin E and of synthetic antioxidants
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
FR2715070A1 (en) * 1994-01-18 1995-07-21 Codif International Sa Lipolytic product isolated from algae
EA000210B1 (en) * 1996-04-08 1998-12-24 Российский Университет Дружбы Народов Compound protecting lever against virus hepatitis

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198432A (en) * 1988-01-29 1993-03-30 Center For Innovative Technology Method of preventing chlorohydrocarbon toxicity using sterol derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3277M (en) * 1963-08-07 1965-03-26 H C Burns Company Composition for the treatment of metabolic degenerations.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3277M (en) * 1963-08-07 1965-03-26 H C Burns Company Composition for the treatment of metabolic degenerations.

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2614205A2 (en) * 1978-10-11 1988-10-28 Bugard Pierre Lipoprotein complex normalising the efficacy of vitamin E and of synthetic antioxidants
EP0243446A1 (en) * 1985-10-15 1987-11-04 Liposome Co Inc Alpha tocopherol-based vesicles.
US5041278A (en) * 1985-10-15 1991-08-20 The Liposome Company, Inc. Alpha tocopherol-based vesicles
US5234634A (en) * 1985-10-15 1993-08-10 The Liposome Company, Inc. Method for preparing alpha-tocopherol vesicles
US5330689A (en) * 1985-10-15 1994-07-19 The Liposome Company, Inc. Entrapment of water-insoluble compound in alpha tocopherol-based vesicles
EP0243446B1 (en) * 1985-10-15 1995-04-19 The Liposome Company, Inc. Alpha tocopherol-based vesicles
FR2715070A1 (en) * 1994-01-18 1995-07-21 Codif International Sa Lipolytic product isolated from algae
US5612038A (en) * 1994-01-18 1997-03-18 Codif Inernational Sa Product with lipolytic activity and its method of preparation
EA000210B1 (en) * 1996-04-08 1998-12-24 Российский Университет Дружбы Народов Compound protecting lever against virus hepatitis

Also Published As

Publication number Publication date
BE871298A (en) 1979-02-15
FR2438481B1 (en) 1981-05-29

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